Yearly Archives: 2022

Mel Gonzales and Fatima-Zhara Amir a scene from 'The Showing'. Photo by Alla Ilyasova

‘Showing’

The Setauket Neighborhood House, 95 Main St., Setauket presents a workshop production of a brand new play produced by Hidden Well Theatre titled Showing on Nov. 5 at 2 p.m. and again at 6 p.m. What’s a gender reveal party without a heaping helping of disaster? Set in the hours leading up to a pregnant woman’s gender reveal party, Showing is an immersive, site-specific play about the ways we strive to make meaning in spaces where there is only chaos and cake. Tickets are $16 in advance at hidden-well-theatre.weebly.com/showing.html or $20 (cash only) at the door. For more information, email [email protected].

Arkarup Banerjee. Photo ciourtesy of CSHL

By Daniel Dunaief

Brain cells don’t always have easily discovered roles, the way various instruments do in an orchestra.

Sometimes, different cells share a function, making it possible to perform various tasks or to process information from the environment, while other times, different cells play their own part in making it possible for an organism to optimize its circuitry to act and react on the world.

So it is for the tufted and mitral cells of land based vertebrates, which are part of the olfactory system, sending signals to the brain about the odors and triggering thoughts about moving towards a desired food or away from the scent of a predator. In many studies, the names have been used interchangeably, as scientists were not sure how to separate them.

Florin Albeanu. Photo courtesy of CSHL

Researchers have spent considerable time studying mitral cells, which project into a region of the brain called the piriform cortex. These cells are nicely organized into one layer, which makes them easy to identify and are bigger in size compared to tufted cells.

Mitral cells, which have been the celebrated stars of the olfactory system, are easier to see and sort out than their nasal cousins, the tufted cells which, by contrast, are slightly smaller.

Recently, two scientists at Cold Spring Harbor Laboratory, Florin Albeanu, an Associate Professor, and Arkarup  Banerjee, an Assistant Professor, published a study that suggested there’s more than meets the eye, or, maybe, the nose, with these tufted cells.

Tufted cells, it turns out, are better at recognizing smells than mitral cells and are critical for one of two parallel neural circuit loops that help the brain process different odor features, according to a study the scientists published in the journal Neuron at the end of September.

“People had assumed mitral cells were very good at” differentiating odor, but “tufted cells are better,” Albeanu said. “How they interact with each other and what the mitral cells are computing in behaving animals remains to be seen.”

Albeanu and Arkarup, who had performed his PhD research in Albeanu’s lab before returning to CSHL in 2020, exposed mice to different odors, from fresh mint to bananas and at different concentrations. They chose these compounds because there are no known toxic effects. The scientists also screened for compounds that elicited strong responses on the dorsal surface of the olfactory bulb that they could access using optical imaging tools.

It is hard to distinguish mitral and tufted cells when doing recordings. Optical imaging, however, enabled them to see through layers and shapes, if they were recording activity in a particular type of cell.

So, Albeanu asked rhetorically, “why is this exciting?”

As it turns out, these two types of cells project to different regions of the brain. Mitral cells travel to the piriform cortex, while tufted cells travel to the anterior olfactory nucleus.

It appears at this point that tufted cells are more likely to share information with other tufted cells, while mitral cells communicate with other mitral cells, as if the olfactory system had two parallel networks. There may yet be cross interactions, Albeanu said.

Mitral cells may be part of a loop that helps enhance and predict smells that are important for an animal to learn. Tufted cells, however, appear superior to mitral cells in representing changes in odor identity and intensity. By flagging the tufted cells as sources of olfactory information, the researchers were able to suggest a different combination of cells through which animals detect smells.

“A large fraction of people in the field would expect that mitral cells and the piriform complex are representing odor identity more so than the tufted cells and the anterior olfactory nucleus, so this is the surprise,” Albeanu explained in an email. Thus far, the reaction in the research community has been positive, he added. 

Throughout the review process, the researchers encountered natural skepticism.

“It remains to be determined how the findings we put forward hold when mice are engaged in odor trigger behavior” as odors are associated with particular meaning such as a reward, an lead to specific actions,” Albeanu explained. “This is what we are currently doing.”

Albeanu added that a few different streams of information may be supported by tufted and mitral cells, depending on the needs of the moment.

Arkarup Banerjee. Photo ciourtesy of CSHL

The study that led to this work started when Banerjee was a PhD student in Albeanu’s lab. Albeanu said that a postdoctoral fellow in his lab, Honggoo Chae, provided complementary work to the efforts of Banerjee in terms of data acquisition and analysis, which is why they are both co-first authors on the study.

For Banerjee, the work with these olfactory cells was an “echo from the past,” Albeanu added. 

As for where the research goes from here, Albeanu said future questions and experiments could take numerous approaches.

Researchers are currently looking for markers or genes that are expressed specifically and differentially in mitral or tufted cells and they have found a few potential candidates. While some markers have been found, these do not sharply label all mitral only versus all tufted cells only.

One of the confounding elements to this search, however, is that these cells have subtypes, which means that not every mitral cell has the same genetic blueprint as other mitral cells.

Another option is to inject an agent like a virus into the piriform cortex and assess whether boosting or suppressing activity in that region in the midst of olfaction alters the behavioral response.

Additionally, researchers could use tools to alter the activity of neurons during behavior using optogenetic approaches, inducing or suppressing activity with cell type specificity and millisecond resolution.

Albeanu would like to test speculation about the roles of these cells in action, while a mice is sampling smells he presents.

By observing the reactions to these smells, he could determine an association between rewards and punishment and anything else he might want to include.

The upshot of this study, Albeanu said, is that an objective observer would have much less trouble extracting information about the identity and intensity of a smell from a tufted cell as compared with a mitral cell.

Tufted cells had been “slightly more mysterious” up until the current study.

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Suffolk County police car. File photo

Suffolk County Police Fourth Squad detectives are investigating following a partial building collapse that injured six people, three critically, in St. James on Nov. 3.

Six construction workers were on scaffolds dismantling the front façade of 840 Middle Country Road when the façade fell on them, knocking them off the scaffolding at approximately 1:30 p.m. The workers for Sit Back & Relax Ground Maintenance fell more than 20 feet. All six men were transported to Stony Brook University Hospital. One of the men was airlifted via Suffolk County Police helicopter.

The Occupational Safety and Health Administration (OSHA) was notified and is investigating. The Smithtown Building Inspector and Smithtown Fire Marshal responded.

Stony Brook Grist Mill. Image from WMHO

Didn’t have a chance to tour the Stony Brook Grist Mill this season? You’re in luck! The mill’s season has been extended for one more day!

Tour the Stony Brook Grist Mill, circa 1751, 100 Harbor Road, Stony Brook this Sunday, Nov. 6, between 1 p.m. and 4 p.m before it closes for the winter.

Long Island’s most completely equipped working mill, it is listed on the National and New York State Register of Historic Places. Visit the Country Store and watch the miller grind grain into flour just as it was done during the Revolutionary War.

Tickets for the tour are $4 for adults and $2 for children. Cash only.  For additional info, call 631-751-2244.

Emma S. Clark Memorial Library, 120 Main St., Setauket is currently holding a Pajamas for Those in Need Drive through Nov. 20. Library staff and volunteers will be collecting new pajamas in any size to be donated to homeless shelters. Donation boxes will be located in the Library lobby to the left of the Circulation Desk, and all are welcome to donate (residents or nonresidents) during Library hours. For more information, call 631-941-4080.

Incumbent state Sen. Anthony Palumbo and Democratic Party nominee Skyler Johnson. Photos by Raymond Janis

In the race for New York’s 1st state Senate District, incumbent Sen. Anthony Palumbo (R-New Suffolk) is competing against  Democratic Gen Z challenger Skyler Johnson of Mount Sinai.

In an office debate, these two candidates offered their perspectives on assorted topics affecting this area.

Introductions

Palumbo has served in elective office for nearly a decade, first in the state Assembly and later in the Senate, where he is completing his first term. He is also a practicing criminal defense attorney. 

Johnson currently sits on the board of Temple Beth Emeth of Mount Sinai. Before pursuing state office, he worked under Southampton Village Mayor Jesse Warren and now works for the Brentwood-based nonprofit New Hour for Women & Children – LI, a program for reentry services for formerly incarcerated women and their families. If elected, he would be the youngest person to serve in the state Legislature since Theodore Roosevelt.

LIRR electrification

Electrification of the Port Jefferson Branch line is an area of agreement for the two state Senate candidates. Johnson intends to use his office to apply direct pressure on the MTA-LIRR to get there.

“I’d like to make sure that we’re bringing home funds for the MTA, making sure that the project is properly funded, as well as making sure that there is enough transparency in the process,” he said. “I want to make sure that I’m communicating with environmental and transit advocacy groups to get them involved and make sure that from the public side, they’re also putting pressure on the MTA.”

Palumbo said cleaning up the Lawrence Aviation Superfund site is nearly completed, after which serious deliberations can occur on electrification. “I think that would really get the ball rolling, and then it really does come down to funding,” he said. “I know many people have been clamoring for it. They’ve been asking about it. … It actually is ripe to do it at this point.”

Cost of living

In communities throughout the 1st Senate District, the area is simultaneously experiencing an exodus of residents from the region while encountering difficulties attracting new families. To counteract these trends, Johnson advocated confronting the various facets of the problem in their entirety.

“As a young person trying to invest in my future, trying to invest in my community, I can say that it is very hard to afford the cost of living here,” he said. “It is very hard to find anything remotely affordable to rent, buy or live in our community.”

When discussing the issue of declining student enrollment in school districts, Johnson further pressed this point: “Our schools are not going to seem attractive if people cannot actually get to them, if people cannot afford to buy within our communities,” he said.

Palumbo, on the other hand, said keeping families in the area requires supporting small businesses, which he called the “backbone of our economy.”

“Business owners are not going to operate their business at a loss,” he said. “They’re going to do what they can. Their margins are tight enough in this state. … I think that’s where it starts and, of course, affordable housing and all of those other issues.”

Elaborating upon this position, Palumbo supported cutting taxes on businesses and offering incentives to keep them in New York, including reducing the minimum wage.

“We’ve been doing what we can to help these small businesses get started, but I feel like it’s almost at the point where we need to give [them] a leg up,” the state senator said. “We need to create huge exemptions. … How about an exception for businesses with 10 or less employees?”

Drawing a clear distinction, Johnson said keeping the area populated starts with paying workers a fair wage. “We need to pay workers fairly,” he said. “I fully support the current minimum wage, and I want to make sure that we’re doing everything that we can to expand workers wages, not reduce them, because that doesn’t help anyone.”

While much of the conversation on housing surrounds renters, Palumbo said more opportunities to support buyers need to be in place. “It’s not always about renting,” he said. “It’s about affordable housing purchases,” adding that subsidizing first-time homebuyers “is huge.”

For Johnson, the problem has gradually compounded over time. “It is really not good that people cannot afford to buy, that people cannot afford to rent and that people cannot afford to stay here long term,” he said.

Environment

Throughout the 1st District, rising sea levels, increased flooding and intensifying storms threaten waterfront properties. In Johnson’s view, the problem is twofold. It first requires action on the part of the state to reinforce natural barriers to protect coastlines. However, these issues are part of a broader effort to reduce carbon emissions and counteract climate change.

“At the end of the day, this all ties into the fight against climate change,” he said. “It is all about investing in natural energy, doing everything we can to fight the effects of sea-level rise.”

For Palumbo, policymakers can work to resolve these matters through several initiatives. “The sea level is gradually rising,” he said. “There needs to be a big plan and, unfortunately, it’s going to take [money], and the government has to be fully committed, which I think we are in New York.”

For the erosion issue at East Beach bluff in Port Jefferson, Johnson said coastal resilience efforts are a matter of shoreline hardening, but saying there is not “a one-size-fits-all approach.”

“Unfortunately, there are going to be places where we need to retreat, where there’s not much else that we can do,” he said. “At the end of the day, I’m committed to investing in environmental infrastructure, in making sure that we’re fighting erosion, making sure that we are proactively having engineers who can examine the situations.”

Palumbo agreed with Johnson, stating that shoreline resiliency depends upon the project and should be evaluated case by case.

“There’s a balance that needs to be struck, of course, between what is reasonably feasible for the particular area,” the state senator said. “The bottom line is I do think it would depend on the project.”

Marijuana

With the statewide legalization of marijuana, there will be emerging debates over the future of the substance within communities. The candidates offered similar perspectives when asked whether there should be restrictions on the number of dispensaries and whether the plant should be grown in their district.

“I’m a less-government-is-more kind of guy,” Palumbo said. “There will be a lot of comments, no question, when that’s decided, and if at all, it should always be done with public input.”

He added, “It’s farming. It clearly is farming, but obviously, the nature of it is such that it’s not just like you’re farming corn. … I think siting is very important — where it’s going to be — and I think public input is extremely important.”

Johnson favored growing marijuana in the district, saying it could bolster the local economy and assist farmers. 

“Moving forward, I think it would be beneficial to have some growth within our agriculture communities,” he said. “I think the funds that will come from that will be really important. I think that they could be used to invest into our roads, our infrastructure, into a lot of the programs that I want to see take place.”

Polarization/partisanship

Palumbo believes the problem of polarization in politics is further magnified in the age of social media. He advocates returning debates to matters of policy and removing personal attacks.

“I don’t think we need to be impolite, that we need to go after each other’s policies and not the other person,” he said. “I’ve always maintained that sort of a manner in conducting business, and I’m hopeful that we’re going to get back there, and we will.” He added, “I think that happens when we have a diversity of thought.”

Despite their differences on many policy grounds, Johnson thanked his opponent for his willingness to engage in a dialogue. 

“Senator Palumbo, we disagree on a lot of things, but you’ve always been willing to have a conversation, and I appreciate that,” Johnson said. “I think maintaining an open dialogue is really important to creating bipartisanship, to working across party lines.”

He added, “Whoever of us wins, I think we will be able to have conversations across the aisle. I hope we can return to a place of civility.”

Voters will have the final word on these two candidates for state Senate District 1 on Tuesday, Nov. 8.

Open cast call

Save the date! Theatre Three, 412 Main St., Port Jefferson, will hold open auditions for Pride@Prejudice, by Daniel Elihu Kramer, adapted from Jane Austen’s novel, on Sunday, Nov. 27 and Wednesday, Nov. 30, at 7 p.m. Seeking four versatile performers to play over two dozen characters. Performances will be held from April 7 to May 6, 2023. Bring a picture/resume. Rehearsals begin in February. For full details visit http://theatrethree.com/auditions.html.

Author Sarah S. Anker at Cedar Beach in Mount Sinai with a copy of her first children's book. Photo by Michael Toscanini

By Melissa Arnold 

Sarah S. Anker was born on a Navy base and lived all over the country before her family finally settled down in central Florida. She loved living amongst the orange groves, woodlands and even the swamps. But with time, the area began to change, giving way to urban development and the sprawling complex of Walt Disney World. Some of the ponds and lakes have evaporated. 

“You have to be careful with nature, because once you lose it, it’s really hard to get back,” said Anker. “And we’re seeing so much of that loss all over the world, not only in woodland but in wildlife.”

Anker raised three children in Suffolk County, which she’s called home for 35 years, and quickly became aware of issues impacting the environment here as well. 

Among them are the gyres — large systems of circulating ocean currents — that have become clogged with plastic waste, slowing the oceans’ circulation and speeding up climate change.

In addition to her ongoing career in the Suffolk County Legislature, Anker’s concern for the environment inspired her to write Below the Ocean: Keeping Our Sea Friends Safe. Through the perspective of a young seal named Sophia who becomes entangled in undersea garbage, kids will learn about threats facing ocean life and what they can do to make a difference. Vibrant and expressive illustrations will make this book captivating for children of all ages. 

How did you get interested in writing? 

My mother was a writer of short stories and poetry, and she always dreamed of getting published. I was a news reporter, photographer and graphic designer for a long time before I began my political career. So the desire to write was always with me.

Why did you decide to write a book for children?

I have children myself, and before that I loved reading lots of books to the children at the preschool where my mother worked while I was growing up. It’s important to influence children in a positive way and give them a greater understanding of how to take care of their world. Our future generation needs to understand how important our environment is, and their role in protecting it. We all need to do more.

What is this book about?

Below the Ocean tells the story of Sophia the seal as she learns about the ocean, how it affects people and sea life, and what she can do to help stop ocean pollution. 

When did you first get involved with environmental protection efforts?

I’ve been doing environmental work as far back as high school, helping out with beach cleanups and other activities like the Future Farmers of America. When I moved to Long Island, I joined the Sierra Club and other civic organizations looking to address pollution in the area, and around 20 years ago I founded a not-for-profit organization called the Community Health and Environment Coalition (CHEC) to address the issue of cancer and how it relates to the environment.

Why are these issues so important to you?

My grandmother passed away from breast cancer when I was pregnant with my daughter Rachel. The New York State Department of Health’s cancer map has shown increased rates of cancer in our area, and I have always believed that the environment directly impacts our health. We not only need to clean up the damage that’s been done in the past, but preserve our environment for future generations as well. 

What do you hope kids will learn from reading this book?

Each individual person, adults and children, has a part that they can play in helping the environment. We can all recycle. We can all help to clean up garbage that we see. We can all go to public meetings to contribute our ideas and find out what needs to be done to address problems. There is a lot of work to do, but all of us can do something.

What was the publication process like? Did you self-publish or use a traditional publisher?

With my background, I decided to create my own publishing company called Anker Books. I wanted to be able to work on the project at my own pace and have more freedom over what the final book would be like. There was a lot of research involved in learning how to self-publish, and I ultimately went through Kindle Direct Publishing for part of that process. They weren’t able to publish a large size, so I also published through another company called IngramSpark. 

Who is the illustrator for this book? 

The illustrator, Lily Liu, is a Chinese woman who lives in France. I found her on the website Upwork, and was amazed by her incredible talent and how rich her illustrations were — the vivid colors and emotion she was able to capture on the characters’ faces. I gave her creative freedom and she has been amazing to work with.

Is there an age recommendation for this book?

Not specifically, but I’d say that kids from ages 2 to about 10 would find something to enjoy about it. It’s a picture book with expressive animals and there’s a storyline to it, but there’s also scientific information and an educational component that older children can benefit from as well. 

What are some things we can all do to take care of the natural world?

Help clean up pollution you see around you. Go to local meetings and advocate for policies that protect our environment. Write to your elected officials about the issues that are meaningful to you. Try to focus on how you can reuse materials instead of always buying new.

Do you plan to write more books in the future?

This will be one of many books for children I hope to publish. I also hope to use Anker Books to support other authors as well. 

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Below the Ocean: Keeping Our Sea Friends Safe is available online at popular retailers including Amazon and Barnes and Noble. Join Sarah Anker for Children’s Storytime at Barnes and Noble at the Smith Haven Mall in Lake Grove on Saturday, Nov. 12 at 11 a.m. followed by a Q&A session and book signing. 

Learn more about the author’s writing and how you can help the environment at www.ankerbooks.com.

Photo from SCPD
Suffolk County Police Sixth Precinct officers are investigating an incident where a candy bar received from trick or treating was found with a razor blade inside the bar.

A 13-year-old girl was trick or treating on October 31 and then traded candy with her classmates at PJ Gelinas Junior High School over the past few days. The girl found a razor blade in a mini 3 Musketeers bar ton Nov. 3 and her mother reported it to police at approximately 7:35 p.m.

Police are asking residents to make sure adults are present when children open candy they received from trick or treating, especially in Stony Brook and Setauket.

Officers are asking anyone with information to call the Sixth Precinct Crime Section at 631-854-8626, or anonymously to Crime Stoppers at 1-800-220-TIPS.

Photo from WMHO

CHANGING OF THE WATCH

Anthony BonGiovanni, owner of Rocky Point Jewelers West, 137 Main Street in Stony Brook Village, met with Eric Baker, owner of Ecolin Jewelers, to wish him good luck as Ecolin takes over the location.

Rocky Point Jewelers will stay in business as they consolidate to their Rocky Point store. With 50 years in the jewelry industry, Ecolin Jewelers will be opening in Stony Brook Village in late-November.