Times of Huntington-Northport

The Suffolk County Vanderbilt Museum, 180 Little Neck Road, Centerport will kick off the first of a series of Thankful Thursdays on March 10 at 7 p.m. in the Reichert Planetarium. Funding is generously provided by BAE Systems.

The evenings will feature a family-friendly planetarium show. After the show, astronomy educators will invite visitors to look through telescopes at the night sky – weather permitting.

The featured show on March 10 is Stars: The Powerhouses of the Universe. This intriguing show takes the audience on a journey to the farthest reaches of the galaxy to experience both the awesome beauty and destructive power of stars. Narrated by actor Mark Hamill of Star Wars.

The event is free, but registration is required.

The Northport Tigers led by two points with 41 seconds left in the game but Half Hollow Hills East retied the game at 43 all with nine seconds left in the Suffolk County Class AA finals.

Northport senior Nick Watts got the inbound pass and let a three pointer fly that just rimmed out forcing overtime as the clock ran out. The T-Birds found their second wind in the in the final 90 seconds of the four-minute overtime period for a 56-50 victory at Smithtown East High School Mar. 5. 

Watts led his team in scoring with five field goals, a three pointer and two free throws for 17 points and teammate Brendan Carr a junior sank five 3-pointers for 15 points. 

Northport concludes their 2021-22 campaign with an impressive 21-3 record.

Jose M. Adrover and Mikala Egeblad. Photo by Lijuan Sun

By Daniel Dunaief

Cold Spring Harbor Laboratory Professor Mikala Egeblad thought she saw something familiar at the beginning of the pandemic.

Mikala Egeblad. Photo from CSHL

Egeblad has focused on the way the immune system’s defenses can exacerbate cancer and other diseases. Specifically, she studies the way a type of white blood cell produces an abundance of neutrophil extracellular traps or NETs that can break down diseased and healthy cells indiscriminately. She thought potentially high concentrations of these NETs could have been playing a role in the worst cases of COVID.

“We got the idea that NETs were involved in COVID-19 from the early reports from China and Italy” that described how the sickest patients had severe lung damage, clotting events and damage to their kidneys, which was what she’d expect from overactive NETs, Egeblad explained in an email.

Recently, she, her post doctoral researcher Jose M. Adrover and collaborators at Weill Cornell Medical College and the Icahn School of Medicine at Mt. Sinai proved that this hypothesis had merit. They showed in hamsters infected with COVID and in mice with acute lung injuries that disabling these NETs improved the health of these rodents, which strongly suggested that NETs are playing a role in COVID-19.

“It was very exciting to go from forming a hypothesis to showing it was correct in the context of a complete new disease and within a relatively short time period,” Egeblad wrote.

Egeblad, Andover and their collaborators recently published their work in the Journal of Clinical Investigation Insight.

Importantly, reducing the NETs did not alter how much virus was in the lungs of the hamsters, which suggests that reducing NETs didn’t weaken the immune system’s response to the virus.

Additional experiments would be necessary to prove this is true for people battling the worst symptoms of COVID-19, Egeblad added.

While the research is in the early stages, it advances the understanding of the importance of NETs and offers a potential approach to treating COVID-19.

An unexpected direction

Jose Adrover. Photo from CSHL

When Adrover arrived from Spain, where he had earned his PhD from the Universidad Complutense de Madrid and had conducted research as a post doctoral fellow at the Spanish Center for Cardiovascular Research in March of 2020, he expected to do immune-related cancer research.

Within weeks, however, the world changed. Like other researchers at CSHL and around the world, Egeblad and Adrover redirected their efforts towards combating COVID.

Egeblad and Andover “were thinking about the virus and what was going on and we thought about trying to do something,” Adrover said. 

Egeblad and Adrover weren’t trying to fight the virus but rather the danger from overactive NETs in the immune system.

Finding an approved drug

Even though they were searching for a way to calm an immune system responding to a new threat, Egeblad and Adrover hoped to find a drug that was already approved.

After all, the process of developing a drug, testing its safety, and getting Food and Drug Administration approval is costly and time-consuming. 

That’s where Juliane Daßler-Plenker, also a postdoctoral fellow in Egeblad’s lab, came in. Daßler-Plenker conducted a literature search and found disulfiram, a drug approved in the 1950’s to treat alcohol use disorder. Specifically, she found a preprint reporting that disulfuram can target a key molecule in macrophages, which are another immune cell. Since the researchers knew this was important for the formation of NETs, Daßler-Plenker proposed that the lab test it.

Working with Weill Cornell Medical College and the Icahn School of Medicine at Mt. Sinai, Adrover explored the effect of disulfiram, among several other possible treatments, on NET production.

Using purified neutrophils from mice and from humans, Adrover discovered that disulfiram was the most effective treatment to block the formation of NETs.

He, Assistant Professor Robert Schwartz’s staff at Weill Cornell and Professor Benjamin tenOever at Mt. Sinai tried disulfiram on hamsters infected with SARS-Cov-2. The drug blocked net production and reduced lung injury.

The two experiments were “useful in my opinion as it strengthens our results, since we blocked NETs and injury in two independent models, one of infection and the other of sterile injury,” Adrover said. “Disulfuram worked in both models.”

More work needed

While encouraged by the results, Egeblad cautioned that this work started before the availability of vaccines. The lab is currently investigating how neutrophils in vaccinated people respond to COVID-19.

Still, this research offered potential promise for additional work on NETs with some COVID patients and with people whose battles with other diseases could involve some of the same immune-triggered damage.

“Beyond COVID, we are thinking about whether it would be possible to use disulfiram for acute respiratory distress syndrome,” Egeblad said. She thinks the research community has focused more attention on NETs.

“A lot more clinicians are aware of NETs and NETs’ role in diseases, COVID-19 and beyond,” she said. Researchers have developed an “appreciation that they are an important part of the immune response and inflammatory response.”

While researchers currently have methods to test the concentration of NETs in the blood, these tests are not standardized yet for routine clinical use. Egeblad is “sensing that there is more interest in figuring out how and when to target NETs” among companies hoping to discover treatments for COVID and other diseases.

The CSHL researcher said the initial race to gather information has proven that NETs are a potentially important target. Down the road, additional research will address a wide range of questions, including what causes some patients to develop different levels of NETs in response to infections.

Town of Huntington Supervisor Ed Smyth lit Huntington Town Hall in blue and gold lights on  February 26 in support of Ukraine’s fight for freedom.

“I have directed Huntington Town Hall to be illuminated blue and gold as we stand in solidarity with the Ukrainian people fighting for their freedom,” posted Supervisor Ed Smyth on social media. “Thank you to Director of General Services Bill Musto, Town electrician Tony Beigelbeck and staff for their service around the clock.”

Photos courtesy of Town of Huntington

The Tigers of Northport, the No. 2 seed, faced the top seeded Lions of Longwood, both teams with 12-1 winning records in the Class AA final at Smithtown East High School Mar. 5. The Tigers clung to a one-point lead in the closing minutes of the third quarter holding off the Lions 43-42, but Longwood found it’s legs in the final eight minutes of play to win the game, 65-54. 

Northport senior Sophia Yearwood led her team in scoring, nailing five triples for 15 points,. Senior Allison Soule had six from the floor and a free throw for 13, and Kennedy Radziul, a sophomore, netted 11.

The win propels Longwood to the Section XI title game as the large school qualifier where they’ll face the small school winner, West Babylon, at their own home court Mar. 7.

Director of the Heart Rhythm Center at Stony Brook Heart Institute Dr. Eric Rashba is holding the new Watchman FLX device, which provides protection from strokes for people with atrial fibrillation. Photo from Stony Brook Medicine

The butterflies that color backyards are welcome companions for spring and summer. The ones that flutter towards the upper part of people’s chests can be discomforting and disconcerting.

In an effort to spread the word about the most common form of heart arrhythmia amid American Heart Month, the Stony Brook Heart Institute recently held a public discussion of Atrial fibrillation, or A-fib.

Caused by a host of factors, including diabetes, chronic high blood pressure, and advanced age, among others, A-fib can increase the risk of significant long-term health problems, including strokes.

In atrial fibrillation, the heart struggles with mechanical squeezing in the top chamber, or the atrium. Blood doesn’t leave the top part of the heart completely and it can pool and cause clots that break off and cause strokes.

Dr. Eric Rashba, who led the call and is the director of the Heart Rhythm Center at Stony Brook Heart Institute, said in an interview that A-fib is becoming increasingly prevalent.

A-fib “continues to go up rapidly as the population ages,” Rashba said. It occurs in about 10% of the population over 65. “As the population ages, we’ll see more of it.”

The Centers for Disease Control and Prevention estimates that 12.1 million people in the United States will have A-fib over the next decade.

As with many health-related issues, doctors advised residents to try to catch any signs of A-fib early, which improves the likely success of remedies like drugs and surgery.

“We prefer to intervene as early as possible in the course of A-fib,” Dr. Ibraham Almasry, cardiac electrophysiologist at the Stony Brook Heart Institute, said during a call with three other doctors. “The triggers tend to be more discreet and localized and we can target them more effectively.”

Different patients have different levels of awareness of A-fib as it’s occurring.

“Every single patient is different,” said Dr. Roger Ran, cardiac electrophysiologist at the Stony Brook Heart Institute. Some people feel an extra beat and could be “incredibly symptomatic,” while others have fatigue, shortness of breath, chest discomfort, and dizziness.

Still other patients “don’t know they are in it and could be in A-fib all the time.”

Doctors on the call described several monitoring options to test for A-fib.

Dr. Abhijeet Singh, who is also a cardiac electrophysiologist at the Stony Brook Heart Institute, described how the technology to evaluate arrhythmias has improved over the last 20 years.

“People used to wear big devices around their necks,” Singh said on the call, which included about 150 people. “Now, the technology has advanced” and patients can wear comfortable patches for up to 14 days, which record every single heartbeat and allow people to signal when they have symptoms.

Patients can also use an extended holter monitor, which allows doctors to track their heartbeat for up to 30 days, while some patients receive implantable recorders, which doctors insert under the skin during a five-minute procedure. The battery life for those is 4.5 years.

Additionally, some phones have apps that record heartbeats that patients can send by email, Singh said. “We have come a long way in a few years.”

Dr. Roger Fan, a cardiac electrophysiologist at the Stony Brook Heart Institute, added that all these technologies mean that “we are virtually guaranteed to get to the bottom” of any symptoms.

Drugs vs. surgery

Doctors offer patients with confirmed cases of A-fib two primary treatment options: drugs or surgery.

The surgical procedure is called an ablation and involves entering the body through veins in the groin and freezing or burning small areas that are interfering with the heart’s normal rhythm. The procedure breaks up the electrical signals in irregular heartbeats.

Performed under general anesthetic, the procedure generally takes two to three hours. Patients can return home the same day as the operation, Rashba said.

As with any surgery, an ablation has some risks, such as stroke or heart attack, which Rashba said are “very rare” and occur in fewer than one percent of the cases. Additionally, patients may have groin complications, although that, too, has declined as doctors have used ultrasound to visualize the blood vessels.

In extremely rare occasions, some patients also have damage to the esophagus behind the heart, said Rashba, who is also a professor of medicine.

For patients experiencing symptoms like A-fib, doctors recommended a trip to the emergency room, at least the first time.

“If it’s not going away, one, you can reassure yourself, two, you can get treatment, and three, you can get a diagnosis quickly,” said Almasry.

The Stony Brook doctors said choosing the best treatment option depends on the patient.

“Everybody has different manifestations of their A-fib,” said Fan.

Among other questions, doctors consider how dangerous the A-fib is for the patients, how severe the symptoms are, and how much they affect the quality of life.

Doctors urged residents to make the kind of healthy lifestyle choices that keep other systems functioning effectively. Almasry cited a direct correlation between obesity and A-fib.

Reducing body weight by 10%, while keeping the weight off, can reduce the likelihood of A-fib recurrence, he said.

Jae Ryong Kang

Update:  Jae Ryong Kang has been located, unharmed.

 Below is the original Silver Alert.

Suffolk County Police have issued a Silver Alert for a missing Melville man with Alzheimer’s disease.

Jae Ryong Kang, 89, was last seen leaving his home, located at 808 Altessa Blvd., at approximately 10:00 a.m.  Kang was driving a 2011 gray Mercedes Benz with NY license plate FJG-8145.

Kang is Asian,  5 feet 8 inches tall, 140 pounds, with white hair and brown eyes. He wears glasses.  He was last seen wearing a black coat, black corduroy pants and white sneakers.

Detectives are asking anyone with information on Kang’s location to call 911 or the Second Squad at 631-854-8252.

Silver Alert is a program implemented in Suffolk County that allows local law enforcement to share information with media outlets about individuals with special needs who have been reported missing.

Elected officials and community members, above, stand by a table of donations. Photo by Raymond Janis

By Raymond Janis

Last week, Long Island leaders and community members met in Huntington to announce the Long Island-Ukrainian Emergency Response Drive, a collection to address the ongoing humanitarian crisis in Ukraine.

Dr. David Buchin, right, and U. S. Rep. Tom Suozzi. Photo by Raymond Janis

The gathering was held outside the offices of Dr. David Buchin, director of bariatric surgery at Huntington Hospital, and Suffolk County Legislator Stephanie Bontempi (R-Centerport), vice chair of the Committee on Health, who both share a business address. Buchin, an immigrant from the former Soviet bloc nation Uzbekistan, says donation drives such as these will help to alleviate the sufferings of Ukrainians.

“The horrors in the Ukraine, I mean we all see it,” Buchin said. “It breaks my heart like it does for all of us. We must do something to help them all. The hospitals are full, their supplies are low, so we’ve created this Long Island-Ukrainian Emergency Response Drive. We’re calling on everyone to help, anything that can help the Ukrainian people, like blankets, sleeping bags, medical supplies and first aid.”

Rep. Tom Suozzi (D-NY3) was present for the announcement. He applauded the altruism of ordinary Americans doing their part to support Ukraine. He also emphasized the dangers of factionalism amid so much uncertainty abroad.

“Taking action like this to give people an opportunity to make a contribution is a great way to feel that we’re doing something, but we’ve all got to do more,” he said. “We have to hold together. We have to keep Democrats and Republicans holding together. We have to follow the old idea that partisanship stops at the water’s edge. We have to all hold together like we are today.”

Bontempi described growing up in Sweden, a country now endangered by the war. She fears the conflict may spill over into Swedish territory and asked for immediate support.

“My family, I speak to them every day, is very frightened,” Bontempi said. “We need to all be very, very concerned about what this madman [Russian President Vladimir Putin] is doing. I urge everyone to please talk to friends, neighbors [to] donate items. It needs to happen now — not in a week, now. People need help right now.”

Town of Huntington officials praised this public expression of solidarity and humanitarian assistance for the people of Ukraine. Town Councilman Sal Ferro (R) said he believes that Americans and Ukrainians are united under a common purpose, likening this local initiative with the cause of the Ukrainian resistance.

“Every little bit that we do can make a difference,” he said. “We can show the human side, why we live in a free country, why we live in a democracy. That’s what they’re fighting for in Ukraine: to stay free.”

Huntington Town Clerk Andy Raia (R) discussed his own Ukrainian roots. He said his relatives chose to remain in Ukraine to support the war effort and encouraged Long Islanders to do the same.

“The time to act is now,” Raia said. “It was really yesterday, but we need to do more to ensure that Europe stays stable, that democracies around the world are allowed to flourish. This is just a small token of what we need to do to ensure that the fight continues in Ukraine.”

For those seeking to donate, the Long Island-Ukrainian Emergency Response Drive is establishing repositories throughout the Island. Buchin’s and Bontempi’s offices, located at 224 Wall St in Huntington, collected items until the end of the day March 4, and the donations were delivered to the H. Lee Dennison Building in Hauppauge.

Pixabay photo

Town of Huntington Supervisor Ed Smyth is urging all who venture out on Huntington’s waterways to register for a free NYS BoatingSafety Certification Course offered under the Town’s Victoria Gaines Boating Safety Program this March and May. 

 “It is our individual responsibility to prevent avoidable tragedies on the water,” said Supervisor Ed Smyth. “Whether you’re captaining a boat, a passenger, or operate a non-motorized water craft, everyone should be prepared to enjoy Huntington waters safely.” 

 The Town of Huntington offers free Boating Safety Classes in March and May. Attendees who register, attend the full 8-hour course, and pass the test will receive a NYS Boating Safety credential issued by NYS Parks. Questions can be directed to the Harbormaster’s office at (631) 351-3255. Adults and children (ages 10 & up) are welcome to register for the course online: huntingtonny.gov/boater-safety  

 2022 COURSE DATES OFFERED: 

 Huntington Town Hall, 100 Main Street, Town Board Room, Huntington 

Monday & Tuesday, March 7 & 8, 2022 (Must attend both dates) 

5:00pm-9:00pm both nights. 8 hours of course instruction total. 

May 2022 Date to be Announced Soon 

Long Islanders gathered at Babylon Town Hall, above, to show support for Ukrainians. Photo by Carolyn Sackstein

Ukrainian and Russian émigrés, Ukrainian-Americans, local elected officials and Long Islanders of various political stripes demonstrated their support for the defense of Ukrainian sovereignty and against Russian President Vladimir Putin’s illegal war initiated in the wee hours of Feb. 24 against Ukraine. 

Suffolk County Legislator Kevin McCaffrey, below right, was on hand for the rally. Photo by Carolyn Sackstein

While some people rally together in their support for Ukraine, others find their way to church sanctuaries to offer prayers for the safety of Ukrainian soldiers and citizens, who are also taking up arms in defense of their homeland.

Anna Konny, from Vinnytsia, Ukraine, a dental hygienist and U. S. citizen, who lives in Woodmere, attended a rally in Lindenhurst at Babylon Town Hall with her aunt, Nataliya Soliternik, who lives now in Hewlett. 

Konny, draped in the Ukrainian flag, was a vocal advocate for those defending Vinnytsia, a city in west-central Ukraine. She has been able to stay in touch with family and friends who are still in Ukraine by using free calling cards provided by Verizon, T-Mobile and other major communication carriers. 

The dental hygienist showed photos of families using subway stations and basements of municipal buildings as bomb shelters. She claimed these shelters are also being used at night by saboteurs and Russian infiltrators as they hide among the patriots they seek to destroy. By day, these infiltrators use luminous paint to paint the roofs of buildings, barricades and other locations to be targeted during nighttime bombings and artillery shelling. 

Konny advocates for weapons and ammunition to be sent to those fighting from World War I-style trenches surrounding the cities and towns. Someone in the crowd asked if she feared reprisals. Konny’s answer was a firm, “No. If these photos get back to Ukraine, I want my friends and family to know that I stand with them.”

Suffolk County Legislator Kevin McCaffrey (R-Lindenhurst), presiding officer of the Legislature, saw Konny and came over to hear her pleas for aid, both military and medical first aid materials. After speaking with Konny, McCaffrey addressed the crowd to resounding applause. “It is appalling what Vladimir Putin is doing, how he is attacking a sovereign nation like Ukraine,” he said. “It makes us wonder who is next. The Ukrainian people have done nothing to incur the wrath of Vladimir Putin. All of us are encouraged by the fight of the Ukrainian people, who are standing against this aggression. I believe the U.S. should do more to stand up for the Ukrainian people.”

Janet Byler, from Huntington, has children serving in the U. S. Army based in Fort Bragg, North Carolina. She felt compelled to attend the rally to support those serving with NATO forces in Europe. Mark Czachor, of West Babylon, said, “Every American should be supporting Ukraine’s fight. As long as we don’t give up, Putin can’t win.”

On Friday, Feb. 25, the Rev. Bohdan Hedz of St. John the Baptist Ukrainian Catholic Church in Riverhead opened the sanctuary to a resident of Texas, who was born and raised in the Riverhead area. He had returned recently to care for his very elderly parents. He had missed the service which had been celebrated earlier that day but was welcomed by Bohdan to pray in the quiet and intimate sanctuary. Unafraid of reprisals, the gentleman, who wished anonymity for personal privacy reasons, spoke of marrying his Ukrainian wife in Kyiv.

“My wife would leave today to take up arms,” he said. “The world is called to speak and to act. Ukraine will fight!”

During this conversation, a woman from the congregation of St. John the Baptist R.C. Church in Wading River came in with an offering of a bouquet of red roses and a prayer. It was her way of giving support to the local Ukrainian community.

Hedz and his congregation have been raising funds and material support for Ukrainian defense since the Russian invasion of the country in 2014 that resulted in the annexation of Crimea. Hedz expressed the belief that “Putin will not stop at Ukraine.”

With this greater invasion into the whole of Ukraine, Hedz said the defenders of Ukraine need warm winter clothing, personal hygiene medications such as pain relievers, cold and flu treatments, and first aid supplies for treating wounds.

Donations can be dropped off any time at St. John the Baptist Ukrainian Catholic Church located at 820 Pond View Road, Riverhead. If the sanctuary doors are locked, one may call the reverend at 631-727-2766.