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Esther Tsai is one of four scientists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory to be selected by DOE’s Office of Science to receive significant funding through its Early Career Research Program. Photo courtesy of BNL

By Daniel Dunaief

This is part 2 of a 2-part series.

Half of this year’s crop of recipients from New York State for Early Career Awards from the Department of Energy came from Brookhaven National Laboratory.

With ideas for a range of research efforts that have the potential to enhance basic knowledge and lead to technological innovations, two of the four winners earned awards in basic energy science, while the others scored funds from high energy physics and the office of nuclear physics.

“Supporting America’s scientists and researchers early in their careers will ensure the United States remains at the forefront of scientific discovery,” Secretary of Energy Jennifer Granholm said in a statement. The funding provides resources to “find the answers to some of the most complex questions as they establish themselves as experts in their fields.”

The DOE chose the four BNL recipients based on peer review by outside scientific experts. All eligible researchers had to have earned their PhDs within the previous 12 years and had to conduct research within the scope of the Office of Science’s eight major program areas.

Last week, the TBR News Media  highlighted the work of Elizabeth Brost and Derong Xu. This week, we will feature the efforts of Esther Tsai and Joanna Zajac.

Esther Tsai

Esther Tsai is one of four scientists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory to be selected by DOE’s Office of Science to receive significant funding through its Early Career Research Program. Photo courtesy of BNL

Listening to her in-laws argue over whom Alexa, the virtual assistant, listens to more, Esther Tsai had an idea for how to help the scientists who trek to BNL for their experiments. As a member of the beamline staff at the National Synchrotron Lightsource II, Tsai knew firsthand the struggles staff and visiting scientists face during experiments.

Artificial intelligence systems, she reasoned, could help bridge the knowledge gap between different domain experts and train students and future generations of scientists, some of whom might not be familiar with the coding language of Python.

In work titled “Virtual Scientific Companion for Synchrotron Beamlines,” Tsai, who is a scientist in the Electronic Nanomaterials Group of the Center for Functional Nanomaterials, is developing a virtual scientific companion called VISION. The system, which is based on a natural language based interaction, will translate English to programming language Python. 

“VISION will allow for easy, intuitive and customized operation for instruments without programming experience or deep understanding of the control system,” said Tsai.

The system could increase the efficiency of experiments, while reducing bottlenecks at the lightsource, which is a resource that is in high demand among researchers throughout the country and the world.

Staff spend about 20 percent of user-support time on training new users, setting up operation and analysis protocols and performing data interpretation, Tsai estimated. Beamline staff often have to explain how Python works to control the instrument and analyze data.

VISION, however, can assist with or perform all of those efforts, which could increase the efficiency of scientific discoveries.

After the initial feelings of shock at receiving the award and gratitude for the support she received during the award preparation, Tsai shared the news with friends and family and then went to the beamline to support users over the weekend.

As a child, Tsai loved LEGO and jigsaw puzzles and enjoyed building objects and solving problems. Science offers the most interesting “puzzles to solve and endless possibilities for new inventions.”

Tsai appreciates the support she received from her parents, who offered encouragement throughout her study and career. Her father Tang Tsai, who is a a retired professor in Taiwan, often thought about research and scribbled equations on napkins while waiting for food in restaurants. On trips, he’d bring papers to read and shared his thoughts. Tsai’s mom Grace, a professor in management in Taiwan who plans to retire soon, also supported her daughter’s work. Both parents read press releases about Tsai’s research and shared their experience in academia.

Tsai thinks it’s exciting to make the imaginary world of Star Trek and other science fiction stories a reality through human-AI interactions.

Joanna Zajac

From left, Joanna Zajac is one of four scientists at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory to be selected by DOE’s Office of Science to receive significant funding through its Early Career Research Program. Photo courtesy of BNL

A quantum scientist in the Instrumentation Division, Joanna Zajac is developing a fundamental understanding of fast light-matter interconnects that could facilitate long distance quantum networks.

Zajac will design and build systems that use quantum dots to generate single photos in the wavelengths used for optical telecommunications.

These quantum dots could potentially generate photons that would work at telecommunication and atomic wavelengths, which could reduce the losses to almost nothing when quantum information travels through the current optical fibers network. Losses are currently around 3.5 decibels per kilometer, Zajac explained in an email.

By coupling quantum dot single photons with alkali vapors, the light-matter interconnects may operate as a basis for quantum information, making up nodes of quantum network connected by optical links.

“Within this project, we are going to develop fundamental understanding of interactions therein allowing us to develop components of long-distance quantum networks,” Zajac said in a statement. “This DOE award gives me a fantastic opportunity to explore this important topic among the vibrant scientific community in Brookhaven Lab’s Instrumentation Division and beyond.”

Zajac explained that she was excited to learn that her project had been selected for this prestigious award. “I have no doubt that we have fascinating physics to learn,” she added.

In her first year, she would like to set up her lab space to conduct these measurements. This will also include development experimental infrastructure such as microscopes and table-top optical experiments. She hopes to have some proof-of-principle experiments. 

She has served as a mentor for numerous junior scientists and calls herself “passionate” when it comes to working with students and interns.

Zajac, who received her master’s degree in physics from Southampton University and her PhD in Physics from Cardiff University, said she would like to encourage more women to enter the science, technology, engineering and mathematics fields, “as they are still underrepresented,” she said. “I would encourage them to study STEM subjects and ensure them that they will do just great.”

Million dollar bleachers?

Is the Port Jefferson School District spending unnecessarily, yet again?

The Board of Education on July 11 learned that bids to replace present high school bleachers and press booths came in much higher than the $561,000 allocated in the 2022-23 budget. According to the superintendent of schools [Jessica Schmettan] the bids indicated a cost of “just under a million dollars” for bleachers, with significantly fewer seats than the present ones. The present bleachers seat 1,000 but the replacements will seat less than 600. Doing the math, this works out to spending over $1,600 per person on a bleacher bench.

The superintendent confirmed in an email that the present bleachers are structurally safe, evident also by the fact that they remain in use. They are not, however, compliant with ADA (Americans with Disabilities Act) code.

Given this huge price tag for a total bleacher replacement, consideration should be given to modifying our present bleachers to make them ADA-compliant. Only the first row would need modification. According to posted information, describing how other school districts faced with this issue addressed it, with the addition of some ramps, guard rails and removal of enough bench area to accommodate 10 wheelchairs in just the first row, we can meet ADA standards, retain the present 1,000-person seating capacity and likely stay well below the initially budgeted amount — and certainly way below the million dollar expense for all new bleachers. Extra handrails could also be installed as an option on upper rows of bleachers for additional safety. The press booth can simply remain as is and need not be enhanced.

The Board of Education will be discussing the bleachers at their Aug. 29 meeting. Surely there are more important priorities in our school buildings than spending a million dollars on all new bleachers if the present ones just need some modifications to meet ADA code. Installing a new HVAC system in the high school could be one of them.

Port Jefferson residents are very generous in supporting their schools. Hopefully the school board will in turn show respect for the taxpayers by avoiding more unnecessary or excessive spending.

Gail Sternberg

Port Jefferson

Context for the bombings of Hiroshima and Nagasaki

A firestorm cloud hangs above the Japanese city of Hiroshima following detonation of an atomic bomb on Aug. 6, 1945. Public domain photo

I felt some discomfort after reading Myrna Gordon’s letter [“Remembering Hiroshima and Nagasaki,” Aug. 10] regarding the North Country Peace Group’s vigil around the anniversaries of the dropping of the atomic bombs. 

I think it is clear to all that war is a terrible thing, and I certainly understand the mourning of those killed in wars. My discomfort comes from the selectivity and moral attitude taken by most people I have known, or heard from, regarding these attacks. I apologize if these factors may not apply to the members of the Peace Group.

To start, the letter seems to imply that these bombings were the most devastating ever. Reports note anywhere from 129,000 to 226,000 killed from the combined attacks. Yet, prior to these attacks, the firebombing of Tokyo killed between 80,000 and 100,000 people immediately in one night alone and does not get similar attention.

My bigger concern is the general perception of such mourners that these attacks were a moral atrocity. They fail to look at the overall picture. If the war had not ended this way, we were looking at an invasion of Japan. The estimates are/were that an invasion would have resulted in the loss of over 1 million people. 

While this number alone is large, it fails to note all the descendants that would never be born because of these deaths. I take this very personally because my father likely would have been killed in that invasion and I would never have been born. Millions of people are alive today for that reason. It should also be remembered that this action was our means of ending a war that we did not start. 

Lastly, as I was thinking about this topic during the past week and deciding whether to respond, a new thought came to me. While there has been some reasonable concern about the potential use of nuclear  weapons over the last several decades, one could make a case that their existence has saved many lives and prevented major wars. Once Russia, and later China, had nuclear weapons, we have not had a direct conflict between world superpowers. 

I think this might be because of the mutually assured destruction theory that the superpowers would not launch nuclear preemptive strikes on each other because of the understanding that it would result in both countries destroying each other. Yet another unappreciated benefit.

Joseph Levine

Stony Brook

WRITE TO US … AND KEEP IT LOCAL 

We welcome your letters, especially those responding to our local coverage, replying to other letter writers’ comments and speaking mainly to local themes. Letters should be no longer than 400 words and may be edited for length, libel, style, good taste and uncivil language. They will also be published on our website. We do not publish anonymous letters. Please include an address and phone number for confirmation. Email letters to [email protected] or mail them to TBR News Media, P.O. Box 707, Setauket, NY 11733.

 

METRO photo

When we shop, we often bring our valuables, which total hundreds — if not thousands — of dollars, with us.

Cell phones, wallets, purses and credit cards represent valuable commodities. They can be stolen to score sweet profits. And throughout our community, that is happening right now.

On Aug. 8, Suffolk County Police Department 4th Precinct Inspector David Regina informed the Smithtown Town Board of a pernicious crime happening across Suffolk County retail spaces.

“Criminals and thieves take the opportunity when someone is shopping at Costco or any of these other stores, and they walk by an unsuspecting victim’s shopping cart,” he said. “What they’ll do is they’ll just take out the credit cards or the wallet.”

A criminal can be out the door with our credit cards in the few seconds we may step away from our shopping carts.

At first, victims of this kind of theft do not know they have been victimized. In the time it can take for victims to discover they were robbed and cancel their accounts, the damage has already been done. For law enforcement, Regina noted, this kind of theft is “a very hard crime to target.”

Fortunately, we can all take some simple steps to protect our possessions. We should always keep our valuables in sight and within reach when we shop.

We also encourage our readers to shop lightly, leaving their possessions inside their locked vehicles or — even better — leaving their valuables at home.

If one shops with a handbag or purse, ensure these bags have secure closures. For purse thieves, an open handbag in a public space invites theft.

At TBR News Media, we helped to pioneer the Neighborhood Watch program in Suffolk County. We now advocate for a similar crime watch program for retail centers. As the adage goes, “If you see something, say something.”

Tell a store manager or similar authority about the nefarious activities you witness. Failure to report these incidents of purse theft signals to criminals our tacit approval of these behaviors, incentivizing recidivism. If we wish to see larcenies begin to drop, we must do our part.

Aware of the risks, we can and should shop without fear. Please take care to ensure that shopping can be a safe experience.

Photo courtesy of Stony Brook Athletics

The Stony Brook women’s soccer team (1-1-1, 0-0 CAA) offense erupted to secure their first win of the season after defeating Lafayette College (2-1, 0-0 Patriot League) 3-1 on Aug. 24 at Kenneth P. LaValle Stadium.

The Seawolves wasted no time getting on the board first after sophomore Gabrielle Côté put the pressure on the Leopard defense by centering a ball into the middle of the box that was deflected into the back of the net by a Lafayette defender at the 13th minute to give Stony Brook an early 1-0 lead.

Stony Brook out-shot Lafayette 9-to-1 in the first half and junior Nicolette Pasquarella made a quick-read save at the 23rd minute to keep the 1-0 lead heading into the break.

 Following the half, the squad came out scorching on both sides of the pitch. After a stop by the Seawolves on the defensive side at the 53rd minute, Pasquarella sent a goal-kick to the middle of the field where it was headed by sophomore Luciana Setteducate and sent to senior Reilly Rich. The senior took the ball nearly 40 yards before finding the back of the net with her left foot to give Stony Brook the 2-0 advantage. 

 The Seawolves kept the pressure on by tallying another goal at the 65th minute. Côté took the ball up the right sideline before she hit a rocket into the back of the net to give Stony Brook a 3-0 lead and ultimately the 3-1 victory. 

This was the first ever meeting and victory against Lafayette. 

“I’m happy for the team that they got awarded with the win today,” Head Coach Tobias Bischof remarked postgame. “It was a great effort by everybody involved. We were defensively very stable and created some very good scoring opportunities. Scoring three goals in a game is always nice to see.”

Next up, the Seawolves hit the road for the first time this season on Sunday, Aug. 27 as they head to North Andover, Mass., to battle Merrimack University at noon. This will be the first-ever meeting between these two programs. 

Pan Seared Salmon with Cucumbers and Crème Fraîche

By Heidi Sutton

If it’s simply too hot to cook outdoors, Pan Seared Salmon with Cucumbers and Crème Fraîche offers a reprieve from the heat by putting your stovetop to work. Mix fresh cucumbers, red onion, dill and creme fraiche for a cool, creamy side then sear salmon seasoned with salt and pepper for a savory summer dish.

When you’re ready to head outside and fire up the grill, Cedar Plank Salmon with Miso Soy Glaze combines light, flaky salmon with a sweet homemade sauce to highlight the flavors of the season. Plus, it’s served right off cured cedar planks for an added touch. 

Pan Seared Salmon with Cucumbers and Crème Fraîche

Pan Seared Salmon with Cucumbers and Crème Fraîche

YIELD: Makes 4 servings

INGREDIENTS:

Cucumbers and crème fraîche:

4 cucumbers, sliced 1/8-inch thick (about 4 cups)

1 small red onion, diced

2 tablespoons sea salt

2 tablespoons rice wine vinegar

1tablespoon dill, chopped

1/4 cup crème fraîche

Pan Seared Salmon:

1 1/2 pounds salmon fillet

salt, to taste

pepper, to taste

3 tablespoons grapeseed oil

DIRECTIONS: 

To make cucumbers and crème fraîche: In medium plastic container or flat-bottomed bowl, place cucumbers in single layer then sprinkle in some red onion and some salt. Repeat 4-5 times until all cucumbers and onions are layered. Cover and refrigerate 2-8 hours. Drain water from cucumbers and onions by pressing firmly (do not rinse). Add vinegar and toss to combine. Just before serving, stir in dill and crème fraîche.

To make pan seared salmon: Debone and cut salmon into four pieces; season lightly with salt and pepper, to taste. In large saute pan, heat grapeseed oil and sear salmon. When slightly golden-brown, flip salmon and cook just long enough to sear other side. Remove from pan and place on platter with cucumbers and creme fraiche.

Cedar Plank Salmon with Miso Soy Glaze

Cedar Plank Salmon with Miso Soy Glaze

YIELD: Makes 2 servings

INGREDIENTS:

2 cedar planks

2 teaspoons honey

1 tablespoon white miso

1 tablespoon rice wine vinegar

2 teaspoons soy sauce

1 garlic clove, minced

1 pound salmon fillet, skin on, cut into two pieces

salt and pepper to taste

DIRECTIONS: 

To prepare cedar planks: Soak planks in water 1 hour. Heat oven to 375 F. Wash, oil and bake planks about 10 minutes to cure. Heat grill to medium-high heat for indirect grilling. 

In small bowl, mix honey, miso, rice vinegar, soy sauce and garlic. Cut salmon to fit planks. Season salmon with salt and pepper, to taste; spread miso mixture on flesh side. Let stand at room temperature 10-15 minutes. Lay salmon on planks skin side down. Place planks on grill adjacent to heat source and close lid. 

Cook 15-25 minutes, depending on thickness, until internal temperature reaches 125-135 F. Transfer salmon and planks to platter and serve.

Pixabay photo

By Lisa Scott

Election Day 2023 is Tuesday, November 7 — In about 10 weeks. You won’t see the president, senators, congress, or governor on your ballot so you may decide to “skip this one.” And we’re already surrounded by incessant media reports anticipating the 2024 presidential election. 

However, ignoring the candidates and issues in 2023 local elections would be a big mistake. These elections matter — they affect your daily lives. And learning about local candidates is much harder than in federal races. We’ve all stood in a voting booth with no idea whom to choose for some local races (and may have even left some parts of the ballot blank).

The Harvard Political Review reports that a Johns Hopkins University study in 2018 demonstrated that many Americans lack civic knowledge as it pertains to jurisdictional issues;  about 25% of study participants did not know whether federal or state governments were in charge of law enforcement and about 30% delete not knowing which government creates and enforces zoning laws.

Local elections have real consequences. There is no level of government that is more directly responsible for serving your community than your local elected officials. Whether it is the guarantee of having healthy drinking water or the benefits of maintained streets, infrastructure is a concern that should remain on the forefront of voters’ minds as they consider the candidates of a local election.

In Suffolk County this year, you’ll be able to vote for a new County Executive (CE); there are term limits for CE as well as all 18 Suffolk County Legislature members (who are also on your ballot in 2023). Many of Suffolk’s 10 Towns have Supervisor races, and also Town Board/Council seats and other local offices and some judges. 

Debates and interviews in the next 10 weeks should bring out important issues and allow voters to hear  candidates’ positions. One example of a critical issue is water quality, which has significantly deteriorated in recent years. 

According to Dr. Christopher J. Gobler of Stony Brook University, “Presently, more than 360,000 homes are discharging wastewater into our aquifer, and this practice has exacted a serious toll on our waters. For example, the level of nitrate in our aquifer has steadily risen to 3.8 milligrams per liter, a concentration that has been shown to be epidemiologically associated with a greater risk of gastrointestinal cancers and birth defects.”

“This level of nitrate is also 100 times greater than the amount in surface waters, and more than two decades of research has demonstrated that the discharge of this pollution has had cascading negative effects — stimulating the occurrence of harmful algae blooms that have destroyed our most prized shellfisheries, shading out seagrasses that are critical habitats for fish, and promoting fish kills.”

Our NYS Legislature (not up for election in 2023) had passed a bill as part of the state budget that would empower the voters of Suffolk County to decide whether an increase of 1/8 cent in the county sales tax should be dedicated to protecting water resources by installing sewers and clean water septic systems, while attracting and matching state and federal infrastructure funding — via a referendum on the November 2023 ballot. 

However the county legislation (IR1573) needed to place this referendum on the ballot was not moved forward on a timely basis by a majority of the Suffolk County Legislature before the required deadline for referendums and thus the future of the matching state and federal funds in unclear. The proposed Suffolk County Water Quality Restoration Act, if the proposition had been allowed to appear on the 2023 ballot, would have provided a dedicated and recurring countywide funding source to transform this plan into action. In a democracy, Suffolk voters would have been able to exercise their voice and approve or defeat this plan directly. 

So vote in our 2023 elections — by absentee ballot, early voting from Oct. 28 to Nov. 5, or on Election Day, Nov. 7. To register, check your registration, apply for an absentee ballot, find your polling place, and learn your district numbers visit https://www.elections.ny.gov/. To find out what’s on your ballot, visit Vote411.org 4 weeks before Election Day. 

Lisa Scott is president of the League of Women Voters of Suffolk County a nonprofit, nonpartisan organization that encourages the informed and active participation of citizens in government and influences public policy through education and advocacy. For more information, visit https//my.lwv.org/new-york/suffolk-county. 

Photo by Gretchen Oldrin-Mones

MASTER OF DISGUISE

While removing a downed tree on the Port Jefferson Station Greenway Trail during a Friends of the Greenway cleanup on Aug. 19, Gretchen Oldrin-Mones of Stony Brook spotted this praying mantis and snapped a photo with her iPhone. She writes, “It was almost invisible on a small brown branch, but as it moved to a green leaf it stopped and posed for this ‘portrait.’

Send your Photo of the Week to [email protected]

 

Photo from MetroCreative
Fiber plays an important role in immune system function

By David Dunaief, M.D.

Dr. David Dunaief

Autoimmune disease is an umbrella term that covers more than 80 different diseases (1). Among them are type 1 diabetes, lupus, rheumatoid arthritis (RA), psoriasis, multiple sclerosis, and inflammatory bowel disease. The common thread for all of them is that the body’s immune system is attacking organs, tissues and cells and causing chronic inflammation.

Unfortunately, autoimmune diseases tend to cluster (2). Once you have one, you are at high risk for acquiring others.

Typical medical protocols

Immunosuppressives are the “go-to” treatment for autoimmune issues. In RA, for example, a typical drug regimen includes TNF (tumor necrosis factor) alpha inhibitors, like Remicade (infliximab), and methotrexate. These therapies reduce underlying inflammation by suppressing the immune system and interfering with inflammatory factors. Disease-modifying anti-rheumatic drugs (DMARDs), a class that also includes Plaquenil (hydroxychloroquine), may slow or stop the progression of joint destruction and increase physical functioning.

There are several concerning factors with these treatments.

First, the side-effect profiles are substantial. They include risks for cancers, opportunistic infections and even death (3). Opportunistic infections include diseases like tuberculosis and invasive fungal infections.

It is no surprise that suppressing the immune system would increase the likelihood of infections. Nor is it surprising that cancer rates would increase, since the immune system helps fend off malignancies. One study showed that after 10 years of therapy, the risk of cancer increased by approximately fourfold with the use of immunosuppressives (4).

Second, these drugs were tested and approved using short-term clinical trials; however, many patients are prescribed these therapies for 20 or more years.

So, what other methods are available to treat autoimmune diseases? 

Medical nutrition therapy

Medical nutrition therapy using bioactive compounds and supplementation are being studied. Medical nutrition therapy may have immunomodulatory (immune system regulation) effects on inflammatory factors and on gene expression.

Raising the level of beta-cryptoxanthin, a carotenoid bioactive food component, by a modest amount has a substantial impact in preventing RA. Several studies have also tested dietary interventions in RA treatment (5). Included were fasting followed by a vegetarian diet; a vegan diet; and a Mediterranean diet, among others. All mentioned here showed decreases in inflammatory markers, including c-reactive protein (CRP), and improvements in joint pain and other quality of life concerns.

What are the effects of fish oil?

Fish oil helps your immune system by reducing inflammation and improving your blood chemistry, affecting as many as 1,040 genes (6). In a randomized clinical study, 1.8 grams of eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation had anti-inflammatory effects, suppressing cell signals and transcription factors (proteins involved with gene expression) that are pro-inflammatory.

In RA patients, fish oil helps suppress cartilage degradative enzymes, while also having an anti-inflammatory effect (7). A typical recommendation is to consume about 2 grams of EPA plus DHA to help regulate the immune system. Don’t take these high doses of fish oil without consulting your doctor, since fish oil can have blood-thinning effects.

Can probiotics help?

Approximately 70 percent of your immune system lives in your gut. Probiotics, by populating the gut with live beneficial microorganisms, have immune-modulating effects that decrease inflammation and thus are appropriate for autoimmune diseases. Lactobacillus salvirus and Bifidobacterium longum infantis are two strains that were shown to have positive effects (8, 9).

In a study with Crohn’s disease patients, L. casei and L. bulgaricus reduced the inflammatory factor TNF-alpha (10). To provide balance, I recommend probiotics with Lactobacillus to my patients, especially with autoimmune diseases that affect the intestines, like Crohn’s and ulcerative colitis.

Does fiber intake affect autoimmune disorders?

Fiber has been shown to modulate inflammation by reducing biomarkers, such as CRP. In two separate clinical trials, fiber either reduced or prevented high CRP in patients. In one randomized clinical trial, 30 grams, or about one ounce, of fiber daily from either dietary sources or supplements reduced CRP significantly compared to placebo (11).

In the second trial, which was observational, participants who consumed the highest amount of dietary fiber (greater than 19.5 grams) had reductions in a vast number of inflammatory factors, including CRP, interleukin-1 (IL-1), interleukin-6 (IL-6) and TNF-alpha (12).

Can diet substitute for medication?

Immune system regulation is complex and involves over 1,000 genes, as well as many biomarkers. Bioactive compounds found in high-nutrient foods and supplements can have a profound impact on your immune system’s regulation and may help reset the immune system. Even in severe cases, bioactive compounds in foods may work in tandem with medications to treat autoimmune diseases more effectively and help reduce dosing of some immunosuppressives, minimizing potential side-effects.

This is not hypothetical. I have seen these effects in my practice, where patients have been able to reduce — or even eliminate —immunosuppressives by altering their diets.

References:

(1) niaid.nih.gov. (2) J Autoimmun. 2007;29(1):1. (3) epocrates.com. (4) J Rheumatol 1999;26(8):1705-1714. (5) Front Nutr. 2017; 4: 52. (6) Am J Clin Nutr. 2009 Aug;90(2):415-424. (7) Drugs. 2003;63(9):845-853. (8) Gut. 2003 Jul;52(7):975-980. (9) Antonie Van Leeuwenhoek 1999 Jul-Nov;76(1-4):279-292. (10) Gut. 2002;51(5):659. (11) Arch Intern Med. 2007;167(5):502-506. (12) Nutr Metab (Lond). 2010 May 13;7:42.

Dr. David Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com or consult your personal physician.

Pixabay photo

By Daniel Dunaief

Daniel Dunaief

A pet peeve isn’t something you race out to the breeder, the pound or anywhere else to get because it’ll be a buddy for the rest of your life.

No, a pet peeve is some annoyance that routinely bothers you, like watching someone shake their leg in class or listening to someone blow away the four leaves that dare to fall on their driveway each day.

To that end, I’d like to share some of my own pet peeves, for no other reason than that it’s easier and, perhaps, more fun to focus on the smaller stuff than to worry about, say, global warming, the 2024 election, or the eventual burning out of the sun. Some of these are truly tiny, while others are considerably larger by comparison. If you find that annoying, add that to your own list.

—A perfect dive into a hotel or community pool: yes, it’s lovely and amazing, but people aren’t fish. We shouldn’t be able to enter the water without making a splash or a ripple. When we were teenagers, my brothers and I watched in amazement as a boy about our age perfectly pierced the water during a vacation at a pool in Quebec. Only later did we learn that he was the son of a national diving champion. He should have had his own pool and not unnerved the foolish Americans at a Holiday Inn.

— Endless, personal and vicious criticism at the end of articles: I can’t help laughing when someone writes about how stupid the idea of the article was. Often, someone else suggests that the person A. didn’t have to read the story and B. didn’t need to take the time to comment.

— The knees digging into my back on an airplane: do other passengers care that my back is on the other side of that thin fabric? Perhaps they want some attention or they are eager to share their physical discomfort with others.

— The overwhelming urge to tell me what my dog needs: one man, in particular, who seems to have moved into the neighborhood recently, tells me how my dog looks each day. Yes, it’s hot, and no, I’m not walking him so far that he’s in danger. By stopping me to share his unsolicited dog instructions, he’s extending the time my dog spends in the heat and he’s annoying me.

— The desire other parents have to tell me how to raise my children: news flash — everyone’s children aren’t the same and, oh, by the way, these aren’t your kids.

— The disconnect between the time our children spend on their phones with their friends and the difficulty in connecting by phone with them when they’re away: why are our children on their phones constantly when they’re with us, but they are unreachable by phone when we text them? They remind us that we tell them to “be where they are” when they’re not with us, but they’re not with us when they are with us.

— The people who listen so poorly that they say “oh, that’s nice” when I tell them my pet peeve died: enough said.

— People who tap me on the shoulder to get my attention while they are talking to me at a baseball game: yes, believe it or not, I can multi task. I’m capable of listening to someone else’s story and responding appropriately while watching every pitch and hoping for either a home run or a foul ball that comes my way.

— People who commit my mistakes to memory: I don’t expect perfection and readily admit that I err. If and when I share a thought about someone else’s mistakes, I sometimes receive something to the effect of, “well, you did that, too” or “what you did bothered me 17.28 years ago, too.” Okay, if it annoyed you, why didn’t you say something at the time, instead of waiting until now? Were you hoping I’d say something at some point so you could unburden yourself?

Studies suggest lifestyle approaches to improve symptoms

By David Dunaief, M.D.

Dr. David Dunaief

Irritable bowel syndrome (IBS) symptoms, such as abdominal pain, cramping, bloating, constipation and diarrhea, can directly affect your quality of life. If you are among the estimated 10 to 15 percent of the population that suffers from IBS symptoms, managing these symptoms can become all-consuming (1).

While diagnosing IBS is challenging, physicians use discrete criteria physicians to provide a diagnosis and eliminate more serious possibilities. The Rome IV criteria comprise an international effort to help diagnose and treat functional gastrointestinal disorders. Using these criteria, which include frequency of pain and discomfort over the past three months, alongside a physical exam helps provide a diagnosis.

Fortunately, there are several approaches to improving symptoms that require only modest lifestyle changes.

How is IBS affected by mental state?

The “brain-gut” connection refers to the direct connection between mental state, such as nervousness or anxiety, to gastrointestinal issues, and vice versa.

Mindfulness-based stress reduction was used in a small, but randomized, eight-week clinical trial with IBS (2). Those in the mindfulness group (treatment group) showed statistically significant results in decreased severity of symptoms compared to the control group, both immediately after training and three months post-therapy.

Those in the treatment group were instructed to do meditation, gentle yoga and “body scanning” — focusing on one area of the body for muscle tension detection. The control group attended an IBS support group once a week.

Could gluten be a factor in IBS?

Gluten sensitivity may be an important factor for some IBS patients (3). In a small randomized clinical trial, patients who were given gluten were more likely to complain of uncontrolled symptoms than those who were given a placebo, 68 percent vs. 40 percent, respectively (4). These results were highly statistically significant, and the authors concluded that nonceliac gluten intolerance may exist. 

I suggest to my patients that they might want to start avoiding gluten and then add it back into their diets slowly to see the results.

Does fructose play a role in IBS?

Some IBS patients may suffer from fructose intolerance. In a study, IBS researchers used a breath test to examine this possibility (5). The results were dose-dependent, meaning the higher the dose of fructose, the greater the effect researchers saw. When patients were given a 10 percent fructose solution, only 39 percent tested positive for fructose intolerance, but when they were given a 33 percent solution, 88 percent of patients tested positive.

The symptoms of fructose intolerance included gas, abdominal pain, bloating, belching and alternating bowel habits. The authors concluded that avoidance of fructose may reduce symptoms in some IBS patients.

According to another study, about one-third of IBS patients are fructose intolerant. When on a fructose-restricted diet, symptoms appeared to improve (6). Foods with high levels of fructose include certain fruits, like apples and pears, but not bananas.

Are lactose intolerance and IBS connected?

Another small study found that about one-quarter of patients with IBS also have lactose intolerance (7). 

Of the IBS patients who were also lactose intolerant, there was a marked improvement in symptoms at both six weeks and five years when placed on a lactose-restricted diet.

Though the trial was small, the results were statistically significant, which is impressive. Both the patient compliance and long-term effects were excellent, and visits to outpatient clinics were reduced by 75 percent. This demonstrates that it is probably worthwhile to test patients who have IBS symptoms for lactose intolerance.

Will probiotics help with IBS?

A study that analyzed 42 trials focused on treatment with probiotics shows there may be a benefit to probiotics, although the objectives, or endpoints, were different in each trial (8).

Probiotics do show promise, including the two most common strains, Lactobacilli and Bifidobacteri, which were covered in the review.

Is there a link between IBS and migraines?

A preliminary study has suggested there may be a link between IBS and migraine and tension-type headaches. The study of 320 participants, 107 with migraine, 107 with IBS, 53 with episodic tension-type headaches (ETTH), and 53 healthy individuals, identified significant occurrence crossover among those with migraine, IBS and ETTH. Researchers also found that these three groups had at least one gene that was distinct from healthy participants. Their hope is that this information will lead to more robust studies that could result in new treatment options (9).

All of these studies provide hope for IBS patients. These are treatment options that involve modest lifestyle changes. Since the causes can vary, a strong patient-doctor connection can help in selecting an approach that provides the greatest symptom reduction for each patient.

References:

(1) American College of Gastroenterology [GI.org]. (2) Am J Gastroenterol. 2011 Sep;106(9):1678-1688. (3) Am J Gastroenterol. 2011 Mar;106(3):516-518. (4) Am J Gastroenterol. 2011 Mar;106(3):508-514. (5) Am J Gastroenterol. 2003 June;98(6):1348-1353. (6) J Clin Gastroenterol. 2008 Mar;42(3):233-238. (7) Eur J Gastroenterol Hepatol. 2001 Aug;13(8):941-944. (8) Aliment Pharmacol Ther. 2012 Feb;35(4):403-413. (9) American Academy of Neurology 2016, Abstract 3367.

Dr. David Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com or consult your personal physician.