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Dr. Aleena Zahra/St. Charles Hospital

By Daniel Dunaief

Bird flu, which is a virus that has so far primarily infected animals, has affected a duck farm in Aquebogue.

Amid concerns about transmission, Crescent Duck Farm, which has operated as a family business since 1908, has had to put down close to 100,000 ducks.

At this point, health officials haven’t reported any cases of humans contracting the virus, although the farm, its workers and doctors have been looking out for signs of illness.

Local doctors suggested that the risk to humans from bird flu is limited to those people who have worked with or handled sick birds.

Dr. Adrian Popp, chair of Infection Control at Huntington Hospital/ Northwell Health. File photo

The virus “transmits easily from bird to bird, but so far transmission to humans has not occurred to my knowledge,” Dr. Adrian Popp, chair of Infection Control at Huntington Hospital/ Northwell Health and associate professor of medicine at Hofstra School of Medicine, explained in an email. “There is a theoretical possibility that this can occur, but so far, I think we are safe,” as New York State is monitoring exposed workers.

Doctors urged residents to see a healthcare worker if they have any contact with birds and they develop symptoms such as a fever, conjunctivitis (an eye infection that can include redness or watery eyes), or breathing issues.

“Monitor yourself for 10 days after exposure,” urged Dr. Aleena Zahra, infectious disease physician at St. Charles Hospital. “If you develop any symptoms, seek medical attention.”

The treatment for bird flu, which can affect people in ways that are similar to influenza, is to take tamiflu, which is more effective in the earlier stages of an infection.

“If you’re in contact with an animal that is sick, then that would be a potential risk factor,” added Zahra.

Zahra advised residents to avoid picking up a dead bird in their yard without gloves and other safety measures.

Dr. Sharon Nachmann, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital, added that the jump to humans from other animals is rarely happening.

People who have become infected are typically recovering, although one person in Louisiana died from the virus.

Despite the relatively low risk, viruses have the ability to mutate, which could make them more transmissible and more dangerous.

CDC silence

At the same time, local doctors are concerned that the Centers for Disease Control and Prevention has stopped publishing information on infectious diseases.

“This is an unprecedented attack on timely access to reports about transmission of various infectious diseases in the country and worldwide,” Popp explained. “It will lead to delayed prevention measures, poor health care, and potentially allowing infectious disease outbreaks to get out of control.”

Dr. Sharon Nachmann/Stony Brook Children’s Hospital

The CDC has created travel bans in the past, but has not closed its reporting on outbreaks, Nachmann said.

“It’s incredibly stressful,” said Nachmann.

Doctors added that they were missing the bigger picture that might offer important information about the source of an illness and the best possible treatment.

“We want to do the best for our patients. We want to tell them that this is working or that is not working and you need a different medication,” Nachmann said.

For right now, doctors are gathering information from state and local officials, said Zahra.

The CDC typically shares details about the specific type of infections in an area or region, its responsiveness to various treatments and its differential impact on any specific subgroup, such as children.

“It is sad to see how political, partisan measures are used to suppress sharing of scientific information between healthcare professionals,” Popp added.

Doctors are hoping for more and better information before too long.

“All we have now is a stop,” said Nachmann. “We don’t know what happens after the stop.”

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Ward Melville High School. File photo

By Sabrina Artusa

The New York State Education Department released data on enrollment, New York State Assessments and Regents scores. Assistant to the Superintendent and Chief Information Officer Laura Pimentel dissected the data in Three Village schools in a presentation on Jan. 22 to the Three Village Central School District.  

Enrollment has decreased to 5,433 students: 75 students less than 2024 and 1,296 students less than 2015. Elementary school enrollment has been consistent throughout the past few years while middle and high schools continue to decrease. 

Despite this, demographic data reveals an increase in English language learners and economically disadvantaged students. 

Elementary and middle school students have somewhat recovered from the post-pandemic chronic absenteeism spike. Of high school students 7.2% are chronically absent: a higher percentage than the previous four years.

If a student misses two days per month, they would be considered chronically absent. The high percentage of chronically absent students occurs concurrent with the increase in economically disadvantaged students and demand for mental health services, Scanlon noted. 

“People look at Three Village and think of a North Shore district doing very well academically. We do have this component that has really created some needs budgetarily and from what we put in the supports,” Superintendent Kevin Scanlon said. 

“We aren’t data-driven because of the opt-out movement and we have to put things in place that are going to give us that data so we can make some decision about our instructional program,” Assistant Superintendent for Educational Services Brian Biscari said. 

NYS assessments

NYS assessments are offered to students from grades 3 through 8, but amid the opt-out movement that has swept Long Island school districts in recent years, no meaningful analysis can be surmised from the data. 

“These assessments help us evaluate the effectiveness of our instructional programs against the state standards, which is something we haven’t been able to do in a quote some time at the elementary and junior high school level,” Pimentel said. 

Of students who opted out,36.4% were from the English assessments, 35.2% from math and 34.3% from science. This contrasts with the federal government requirement that 95% of students take the test. The percentage of student participation is over 20% below the state average in both math and English Language Arts.

The assessments are no longer representative of teacher performance and have no impact on students’ grades. 

“In the absence of that we had to put in other benchmarks…about how we are able to compare students to one another in their grade level and from cohort to cohort as they are coming through, so that is another increase in the district because we have to supplement for what parents aren’t taking that is free with what the state offers,” Scanlon said. “The data is important to us as we try to place students appropriately and give them services appropriately.”

Bond referendum

Jeffery Carlson, interim deputy superintendent and head of the business department discussed funding for district expenses. The district is considering a bond proposal to pay for the $125 million in construction expenses and projects. 

The list of construction projects is aspirational, not realistic. Carlson said that while all the project will be listed, they do not intend to complete them all. 

“Sixty-six percent of the cost comes back to us in building aid. Whatever the cost of the project is, the state is paying two-thirds of the cost. And it isn’t only on the construction cost, it is on the interest as well,” Carlson said.

The bond would mean a $284 tax increase every year for 15 years, which would be the length of the bond. Scanlon said that safety and security projects — “things we must get done” — would be the priority while other projects like air conditioning for elementary school gyms and cafeterias could wait. 

Armed guards

Following a presentation Jan. 8 reviewing the past security measures and future options by Scanlon, the board discussed the possibility of arming guards. The district could arm guards outside the schools or inside the schools. 

Before 2012, secondary schools within the district only had one guard. Since the Sandy Hook shooting, the district added over 500 security cameras, vestibules, sign-in procedures, license readers, employee background checks and a head of security with a background in law enforcement. 

This year, the board also added an AI weapons detection technology called Zero Eyes. Scanlon noted that the district adds cameras every year, so the new tech does not impact the number of cameras added in a year. 

Since many security guards possess the background and clearance to be armed, the district could easily arm guards without having to undergo significant staff changes. 

“I would like to poll parents and students. As a board member who bears no risk whatsoever, I feel that I personally should have very little say in this,” said trustee David McKinnon. “I am happy to follow the lead of the major stakeholders here.”

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By Sabrina Artusa

A science teacher at R.C. Murphy Jr. High School in theThree Village Central School District is now on leave after posting an incendiary political post on Facebook.

The teacher, Pamila Pahuja, wrote in the post, “To all Trump supporters – hope the next time you take a drink it doesn’t swallow right and you go get help but no one is there and you slowly wither away while struggling to gasp and you suffer long.”

The post has sparked outrage from some parents. Others feel Pahuja did nothing wrong.

“I always like to put the shoe on the other foot,” former teacher and Hauppauge resident Dan Simon said, noting that teachers still have the freedom of speech. He added, however, that what she posted was a mistake.  “Should she be doing that? Probably not.”

A father of a middle-school child, Doug said, “Just saying that about another person – it’s not right.” His child does not go to a district school. 

He said that middle-schoolers are still learning right from wrong, and to “say stuff like that, you are kind of brainwashing them. It gets them thinking differently.”

Litigator Andrew Lieb said that there is a case to be made under labor law 201-d, which protects against discrimination for participating in certain activities including political activities outside of working hours and off the employer’s premises. Lieb has worked on similar cases pertaining to teachers.

“That is a hyperbole that wasn’t a specific threat,” Lieb said. “As long as she was off working hours off working premises, she is allowed to do this stuff. She is working for the government and the government can’t block speech.”

“Imagine all these teachers wanting to speak and not being able to have a voice,” he said. “That’s what this does and that’s why these laws are so important. 

Pahuja also wrote, “To all my friends and their families worried, stay safe. America is no longer the land of the free – we are prisoners of the governments. Only a matter of time before they come for all women. Welcome to gilead, it’s on the way.” 

On Jan. 26, the district released a letter to parents notifying them of Pahuja’s absence. 

“Please be assured that we have taken steps to ensure a smooth transition and continued high-quality instruction in science. A qualified and certified science teacher will be assigned to your child’s class in her absence,” the letter, signed by Principal Michael Jantzen, reads.

The Three Village BOE and the Three Village Teachers Association would not comment on matters of personnel.

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File photo by Raymond Janis

First Amendment rights cannot be stopped

Legislator Steve Englebright (D-Setauket) believes that constituents can be controlled and silenced by offering candy as if they were 5 year olds. It’s insulting and degrading that grown adults who speak out against injustices and understand how to use their First Amendment rights to free speech are being silenced. 

No, Steve, a Life Saver isn’t going to make me stop speaking out against the draconian rules that [Suffolk] County passes that harm the public’s general welfare by turning the county police department against the Latino population. The presiding officer infringed and trampled on my First Amendment rights because he didn’t like what I said. 

Let’s face it, the appearance of senior women speaking at public meetings exercising a constitutional protection of free speech surrounded by fully armed sheriff’s officers is bad public relations for the legislative body in a democracy. 

Lisa Sevimli, Patchogue 

We do not need another freight station

I wholeheartedly agree with Frank Konop [Smithtown freight yard is a threat to our community,  [TBR News Media, Jan. 23] that the proposed Townline Rail Terminal will do more harm than good to residents of Smithtown township.  However, his attempt to link it to the wildfires in southern California is way off base.

This has nothing to do with “social justice policies.”  Regarding the California fires, it’s false that they were related in any way to redirecting reservoir water to save fish.  State reservoirs storing water for southern California are at or near record highs.

The elephant in the room is global warming.  Although it’s impossible to narrowly tie it directly to a particular disaster, it’s foolish to deny its role in the increasing prevalence of wildfires, droughts, floods and freak weather.  In March 2024 the Smokehouse Creek fire burned over one million acres in the Texas Panhandle, compared with more than 40,000 acres burned in California thru January 2025.  In October 2024 in Valencia, Spain, 232 people were killed by a year’s worth of rain falling in a few hours.  Right here in Smithtown we were hit by a “rain bomb” last August that destroyed Stony Brook Pond and Stump Pond and flooded town hall.  The Main Branch of Smithtown Library is still closed.

Getting back to the TRT, there are lots of questions.  This facility will be used not only to ship incinerator ash as well as construction and demolition debris off Long Island, but also to transport construction materials, vehicles and other undefined goods and commodities onto Long Island.  What limitations are there?  Will propane, heating oil or hazardous materials be among these commodities?  We don’t know.  What need is there for two transfer buildings, track to accommodate 161 freight cars and a fleet of 50 trucks if this facility will run only one 27-car train in and out per day as its sponsor claims?  Will the tracks become a magnet for illegal dumping, attracting rats and mosquitos?  TRT will undoubtedly have impacts beyond wrecking the Kings Park residential community it’s adjacent to, including the pollution emitted by the 1970s era diesel locomotives pulling all those freight cars. 

The culprit behind this misbegotten proposal is not “social justice policies” or the “Green New Deal,” but our own Smithtown Town Board, which unanimously railroaded it through (pun intended) every step of the way.  It’s now proposing to change town zoning code to add a new use called “rail freight terminal” to districts zoned Light Industrial, of which there are many, including Flowerfield, around town.  Flowerfield was once a Long Island Rail Road station with its own siding track. Could this rezoning affect the disposition of Flowerfield?  The Smithtown Town Board is supposed to protect the interests of Smithtown residents.  But apparently, they’re so sure of being reelected due to their party affiliation that they presume it’s safe to ignore overwhelming opposition to TRT from the community.  And who’s to say they’re wrong?

David Friedman, St. James

Presidency of Dr. Shirley Strum Kenny and Dr. Jack Marburger

As the former president of the Three Village/Stony Brook Soccer Club from 1990 to 2002 and 2010 to 2017, I read with great interest your article on the presidency of Dr. Shirley Strum Kenny and her impact upon the Three Village community. While Dr. Kenny’s support for the local community and especially our local soccer club was second to none, I do not want the article to give the impression, as I think it does, that her predecessor, Dr. Jack Marburger, was not interested in the local community and was only interested in the science aspect of the university. Nothing could be further from the truth, especially as it related to the development of the soccer complex next to the P lot at [Stony Brook] University.

Prior to our request to be able to develop the unused land for a variety of soccer fields, our local soccer club played all of their games at our local schools, forcing our children and families to go from one site to another, or be forced to miss their games. Upon our request to Dr. Marburger to be able to develop the fields, he played a major role in giving us permission to develop the property and ensuring our success even in the face of considerable opposition from the local neighbors and others. Knowing that such a complex would be of great benefit to the larger community, Dr. Marburger made sure that we received a permit from his office and in fact only charged the soccer club $1 a year for the use of the property. I think it is fair to say that without his support and understanding of what such a use would mean to the thousands of children and families in our community there would have been no soccer fields for our community to use on the university campus.

Upon her acceptance of her position, Dr. Kenny continued her support for the decision of Dr. Marburger with regard to the soccer fields, allowing the permit to continue for $1 a year and allowing the soccer club to build a multi-use building which contained both “real bathrooms” for our families as well as a concession stand. In addition she allowed for the soccer club to hold various outdoor and indoor tournaments on the campus, at no charge, including the major tournament on Long Island at that time, the Long Island Junior Soccer League championships. She was a frequent visitor to the fields on Sundays when over two thousand of our children played during the day. She made sure her staff was always supportive of our efforts to improve the complex and supported our efforts to gain a state grant which we did with the support of former State Senator Jim Lack and former State Assemblyman Steve Englebright.

Both Dr. Marburger and Dr. Kenny understood that Stony Brook University is more than just buildings and research. It is a community asset of the Three Villages and as such must be engaged with the local community in more ways that just selling tickets to various events. Unfortunately, neither of their two successors understood how a state university and a larger community must be engaged with each other, to the point where the soccer complex was taken over by the recreation department and charged the local soccer club over $100,000 each year for the ability of our local children to play soccer on land which had been developed by the local soccer club. Unfortunately they looked at the soccer fields solely as a money maker and not as a community benefit, to the point where they now charge for almost everything, significantly reduced the amount of time allotted for games and practices and have closed the building which was built for the benefit of our families.

While one may think that this is all history, it is not, especially as Stony Brook University engages once again in the selection of a new president. The selection committee and the SUNY Board of Trustees must understand that Stony Brook University must be part of the community, as promoted by both Dr. Kenny and Dr. Marburger, and not merely located in our community as made clear by their successors who gratefully have gone on to other places far from here. One would hope that the new president will understand and promote a concept of togetherness and mutual commitment to each other and not just what is good for the university. We hope that the history of what Dr. Kenny and Dr. Marburger accomplished will be the type of history which the new president will provide and not the type of history which their successors failed to provide. Our community is a better place to live when the university understands that it is part of the community and not just located here.

Mitchell H. Pally, Former President

Three Village Soccer Club

1992-2002; 2010-2017

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METRO photo

Stony Brook Medicine (SBM) is partnering with the Suffolk Academy of Medicine to host a Galentine’s Women’s Health Fair aimed at empowering women in Suffolk County with valuable health resources and information. The free, community-focused event will take place on Wednesday, February 12 from 6:30 p.m. to 9:30 p.m. at the Long Island Aquarium, 431 East Main Street in Riverhead.

“Stony Brook Medicine is proud to support the well-being of women in our community and provide them with the resources they need to thrive,” says Carol Gomes, chief executive officer of Stony Brook University Hospital. “Initiatives like this —whether aimed at prevention, education, or care—strengthen the foundation of healthier families and a healthier future.”

“We are thrilled to bring this resource to the women of our community,” said Nicole Gerberg, Executive Director of Suffolk Academy of Medicine. “Women play a pivotal role in shaping healthy families and communities, and this event is a way to give back and support their well-being.”

The fair is open to all Suffolk County residents, 16 years and older and will feature:

  • Educational wellness demonstrations
  • Talks with Stony Brook Medicine health professionals, as well as other medical institutions, including experts in breast cancer, breast imaging, radiology, massage therapy, nutrition, exercise physiology and LGBTQ* healthcare services
  • Sweet treats in honor of Valentine’s Day
  • Raffles
  • A cash bar
  • And more!

*To attend the Valentine’s Women’s Health Fair, the public must RSVP. The form can be found at this link.

About Stony Brook Medicine:

Stony Brook Medicine integrates and elevates all of Stony Brook University’s health-related initiatives: education, research and patient care. It includes five Health Sciences schools — Renaissance School of Medicine, School of Dental Medicine, School of Health Professions, School of Nursing and School of Social Welfare — as well as Stony Brook University Hospital, Stony Brook Southampton Hospital, Stony Brook Eastern Long Island Hospital, Stony Brook Children’s Hospital and more than 200 community-based healthcare settings throughout Suffolk County. To learn more, visit www.stonybrookmedicine.edu.

About Suffolk Academy of Medicine:

The Suffolk Academy of Medicine is dedicated to promoting the health and wellness of Suffolk County residents by providing education, resources, and community outreach.

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METRO photo

By Daniel Dunaief

Daniel Dunaief

A few years ago, a friend of mine called the night before a major operation.

I could tell he was nervous. His usual, unflappable voice was weaker and unsteady, as if he weren’t sure how things would go and was reaching out for encouragement.

“There’s pretty much nothing you can do at this point,” I said. “You really don’t need to be sharp or focused or even attentive tomorrow. You better hope the doctor is getting plenty of rest and is at his best.”

“That’s true,” he laughed. “Maybe I should send over a good dinner or encourage him to go to bed early tonight.”

Doctors, like so many other people in other professions, deal with activities and routines that are unimaginable for the rest of us.

As a child, I watched my father slowly and carefully remove glass from the eyes of a construction worker who had been in an accident. I also sat in horror as he ate a steak just hours after being in surgery for most of the day to reconstruct the eye of a local patient who had suffered extensive trauma.

The medical world’s ability to get past the “ick” factor is pretty incredible. These professionals, on whom we rely for our overall health and for the health of our specific organs and systems, improve and extend our lives, offering the best of modern medicine to counteract the effect of bad habits, hidden genetic problems that can complicate and threaten our lives, and pathogens that cause damage and destruction.

Recently, I visited a urologist. If you’ve been reading this column long enough, you might recall that I’ve had kidney stones. These are exceptionally unpleasant, causing pain and vomiting, among other discomforts.

Long ago, I shuffled into an emergency room, bent over double from the pain. After I told the admitting nurse what was wrong, she didn’t even bother with paperwork or with taking my blood pressure. She immediately took me to a room, where another nurse almost instantly provided a painkiller. I am still grateful to them years later.

So, you see, I feel the need to monitor the health of this system to reduce the risk of future such episodes.

This year, I was meeting with a new urologist. I tried not to think about the parts that are unpleasant but that are much less problematic than a kidney stone.

He knocked politely on the door, as if he might have been delivering a dish of salmon with steamed vegetables and couscous.

Who is it? I was tempted to ask in a falsetto voice. What difference did it make? Anyone who knocked was coming in regardless of what I said.

He washed his hands – thankfully – sat down and asked me to tell him about myself.

“My health history?” I wondered.

“No, I mean, are you married, do you have kids, what do you do for a living?”

Well, I write about weird meetings like this. But enough about me, how do you do what you do? I wondered. No, I didn’t say that. I smiled and offered the 20 second tour of my life. 

We even chatted about the Yankees losing Juan Soto to the Mets. Would they be better or worse this year?

After he asked me about my health history, he told me to lower my pants and underwear and put my elbows on the examining table.

“You’re going to feel some pressure as I examine your prostate,” he said.

I thought of my dog, whose head is often in my lap or near my face when they probe parts of his body he’d just as soon no human ever touched. He makes a face I imagine was similar to mine at that moment. Shocked expressions transcend species.

Afterwards, the urologist smiled at me, gave me a quick assessment and told me he wished me and the Yankees well this year.

Later, I tried to imagine sitting at a meal with him, chatting in an airport waiting room, or standing outside the backstop of a softball field as we waited for the chance to hit.

I couldn’t do it. Routine as his work might be for him and necessary as it might be for me, I struggle to disconnect from an exam that is a routine part of his work.

But, hey, I’m not anticipating that either of us will call the other on our birthdays this year. I’m glad he’s there, doing his thing and hope not to need additional services.

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METRO photo

By Leah S. Dunaief

Leah Dunaief,
Publisher

The articles I’ve read recently call it “financial infidelity” and blame it on some percentage of all couples, but especially on Generation Z. “It” refers to hiding money from each other, or if not exactly hiding, then not sharing either the money itself or its existence. And since money seems to be the primary issue couples argue about over the long term, the question of how much to share is highly relevant to any relationship.

A survey by consumer financial services firm Bankrate indicated that 67 percent of 18 to 28- year-olds hide money information from each other in committed relationships. That drops to 54 percent of millennials, 33 percent of Gen Xers and 30 percent of baby boomers, according to Newsweek. For some reason, older than baby boomers aren’t in the survey. I can try to offer that perspective since I am in the older group.

“Hidden debts, undisclosed spending, or secret accounts can, as well as undermining a partner’s trust, disrupt shared financial plans, such as saving for a home, retirement or children’s education, causing long-term financial strain,” according to the article.

Some 40 percent of couples in the United States have kept secrets from each other about money, according to the study involving 2217 adults. These secrets may include spending more than a partner would approve of (33 percent), keeping hidden debt (23 percent), having a secret credit card (12 percent), a secret savings account (15 percent), or a secret checking account (13 percent).

Yet these figures exist despite 45 percent of those surveyed disapproving of what is termed financial infidelity and even equating it with actual unfaithfulness. If a secret financial situation is discovered, it tends to disrupt the trust that relationships are built upon and perhaps cause speculation over what else might be hidden 

One senior industry analyst, Ted Rossman, maintains, “Money secrets can undermine a relationship. It’s hard enough to meet your financial goals when you are pulling in the same direction. It’s almost impossible when you’re pulling in opposite directions.” 

Rossman goes on to say that being open about your finances doesn’t mean you need to combine all your money. A yours-mine-ours is a possible arrangement for those who feel more comfortable that way.

Despite the importance of money in a marriage or committed relationship, half a century ago, when I was married, money was the last thing on our minds. We were entirely caught up in the romance and didn’t consider the business aspect of lifetime coupling. So when the time came to buy a house, my husband and I counted our pennies and came up a little short for the down payment on the mortgage.

“I’ll take a loan from the bank, using my stocks as collateral,” I said.

“Stocks?” he responded with surprise.

“Yes, I think I have just enough to bridge the difference between our savings and what we need,” I said. “I have been buying a couple of shares of stocks each year with my allowance since I was a child,” I explained. 

It had never occurred to me to tell my husband. Needless to say, he was delighted to discover this mysterious side of me. Marriage arrangements were traditional at that time. The husband was the breadwinner, the wife the homemaker. The husband’s paychecks went into a joint bank account and  both drew from that account for expenses. 

Husbands may have laughed at the saying, “What’s mine is hers and what’s hers is hers,” but they subscribed to it. What we brought to the marriage financially was of little concern since we were young and generally without any serious assets, and we didn’t think of pooling those. We wives were advised then, in women’s magazines for example, to keep a little stash on the side for personal expenditures that needn’t be discussed.

Many couples are older now when they marry, and both work, thus the landscape is different. So I don’t know what to advise. Maybe that’s why we elders weren’t polled.

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Do you recognize this man? Photo from SCPD

Suffolk County Crime Stoppers and Suffolk County Police Sixth Precinct Crime Section officers are seeking the public’s help to identify and locate a man who allegedly stole from an East Setauket store in January.

A man allegedly stole a mixer from Kohl’s, located at 5000 Nesconset Highway, at approximately 10:20 a.m. on January 12. The merchandise was valued at approximately $500.

Suffolk County Crime Stoppers offers a cash reward for information that leads to an arrest. Anyone with information about these incidents can contact Suffolk County Crime Stoppers to submit an anonymous tip by calling 1-800-220-TIPS, utilizing a mobile app which can be downloaded through the App Store or Google Play by searching P3 Tips, or online at www.P3Tips.com. All calls, text messages and emails will be kept confidential.

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Drs. Iwao Ojima, left, and Martin Kaczocha in a Stony Brook University laboratory. Photo by John Griffin, Stony Brook University

A non-opioid investigational drug with promising pre-clinical results in treating neuropathic pain has passed an important hurdle after the study’s safety review committee (SRC) reviewed the data from initial volunteers and recommended to progress into the next dose level in a first-in-human clinical trial.The drug, ART26.12, is being developed by Artelo Biosciences, Inc, based in Solana Beach, Calif.

The compound was discovered and initially developed by Stony Brook University’s Iwao Ojima, PhD, and Martin Kaczocha, PhD. The technology is based on a class of fatty acid binding proteins (FABPs) inhibitors, including what is now ART26.12, and was licensed to Artelo in 2018 by the Research Foundation for the State University of New York.

Neuropathic pain is estimated to affect about eight percent of the U.S. population, which translates to approximately 20 million people. ART26.12 is being developed specifically for chemotherapy-induced peripheral neuropathy, which remains a serious adverse problem for patients during cancer therapy and post therapy.

Dr. Ojima and colleagues selected FABPs as drug targets of the body’s endocannabinoid system to modulate lipids within the cell for a potentially promising way to treat pain, inflammation and cancer. According to Artelo, ART26.12 is the lead compound in Artelo’s proprietary FABP platform and is believed to be the first-ever selective FABP5 inhibitor (5 indicates a specific protein) to enter clinical trials.

The SRC completed its initial clinical safety review of ART26.12 in early January for the first cohort of eight volunteers. With that, the phase 1 clinical trial of this drug will advance to the next step, which will include more subjects and an evaluation of higher doses of the investigational drug. 

Artelo says that other potential indications with the lead compound and other FABP5s in development include treatments related to cancer, osteoarthritis, psoriasis and anxiety.

Dr. Ojima, SUNY Distinguished Professor in the Department of Chemistry at Stony Brook University, and Director of the Institute of Chemical Biology and Drug Discovery, and Dr. Kaczocha, Associate Professor in the Department of Anesthesia in the Renaissance School of Medicine, led the Stony Brook team in its work developing inhibitors to various FABPs.

They continue to consult with Artelo regarding the advancement of these compounds in clinical trials.

For more about the FABP inhibitor story, see this 2024 press release. For more about Artelo’s successful completion of the first cohort in the phase 1 study of ART26.12, see this press release.

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Craig Knapp Photo courtesy of LIMEHOF
Presentation event on Feb. 1 to honor music teacher Craig Knapp

The Long Island Music and Entertainment Hall of Fame (LIMEOHF) recently announced Rocky Point Elementary Music Teacher and Department Chairperson Craig Knapp as its 2024 ‘Educator of Note’ winner. 

“The Long Island Music & Entertainment Hall of Fame is thrilled to honor Craig Knapp with the ‘Educator of Note’ Award and to recognize his extraordinary dedication, innovation, and profound impact on countless students and on music education in our community,” said LIMEHOF Vice Chairman Tom Needham, who manages LIMEHOF’s education programs.

With an impressive career that spans 27 years on Long Island, Knapp is the 18th music teacher to be recognized by LIMEHOF since the ‘Educator of Note’ Award was established in 2007. This award recognizes exceptional teachers who demonstrate a commitment to music education, play an active role in the community, and have a significant influence on the lives of music students of all backgrounds and abilities.

“I am absolutely honored to be inducted into the Long Island Music & Entertainment Hall of Fame as the 2024 recipient of their ‘Educator of Note,’” said Knapp. “To be included on the list of past honorees—many of whom I have worked with collaboratively in a variety of music education organizations, committees, conferences, and initiatives—is both gratifying and humbling. I am very proud that I carved out a successful career in a rather unconventional and unique way.”

Knapp is the director of the Nassau and Suffolk Treble Choirs of the Metropolitan Youth Orchestra of New York, Elementary Classroom Music Specialist and Choral Director in the Rocky Point Public School District, former Adjunct Assistant Professor at Hofstra University, former Director of the Early Childhood Community Music Program at Stony Brook University, music educator, guest conductor, clinician, folk dance leader and author. He says of all his accomplishments, the most significant honor to him is the lasting influence he has had on his students.

“I have the luckiest job in the world as I get to wake up every Monday morning and make music with incredible children,” Knapp said. “Of all that I have achieved—more important than any accolades I could receive, books I could publish, guest conducting opportunities I could receive, invitations to present at professional development conferences, or performances I direct—my greatest accomplishment, and what I’m most proud of, is that students still come to visit me decades later to tell me that I was their favorite teacher and to thank me for the positive impact I had on their life. What could be better than that?”

Knapp will accept the award at a special presentation ceremony on Saturday, Feb. 1st at the LIMEHOF, 97 Main St., Stony Brook at 2 p.m. The event will feature a performance and visual presentation. The public is invited to attend. Tickets are $29.50 per person at www.limusichalloffame.org and at the door. 

For more information, please call 631-689-5888.

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