Stony Brook University

Vanessa Aleksander and Ignacy Liss in a scene from March ‘68. Photo courtesy of Staller Center

Stony Brook University’s Staller Center  for the Arts turns into a movie lover’s mecca when new independent films screen at the Stony Brook Film Festival on evenings and weekends from Thursday, July 20 to Saturday, July 29. The popular festival, now in its 28th year, will become a hub for some of the best filmmakers working today, a meeting ground for favorite actors and rising stars, and a showcase of new masterpieces as it pairs memorable short films with an array of features you won’t see anywhere else.

Presented by Island Federal, this year’s lineup offers 36 films from over 26 countries. The Festival kicks off with the U.S. premiere of the Dutch film Sea of Time. Led by Sallie Harmensen (SkyTV’s Devils), Reinout Scholten van Aschat, and of Danish stage and screen fame Elsie De Brauw, the harrowing, heartbreaking, and ultimately hopeful film is anchored by the powerhouse performances that examine enduring love in times of hardship.

Many international films in this year’s Festival are threaded by this theme of love overcoming life’s difficulties. Whether it is the blossoming young love against all odds in the Polish period drama March ’68, the touching Japanese film Trapped Balloon (starring Toko Miura of the 2022 Oscar-winning film Drive My Car), the gorgeous and romantic love story of My Sailor, My Love with Scottish film icon James Cosmo (Game of Thrones, His Dark Materials) and Tony-Award Winner Bríd Brennan (Dancing at Lughnasa), or the hilarious, music-infused road trip feature Grandpa Goes South from Slovenia.

Continuing on this shared theme of overcoming is Martha, a film that tells the true story of Martha Liebermann, wife to famed painter Max Liebermann, as she faces the Third Reich on own her terms. 

At the same time, the powerful documentary Radioactive, directed by Stony Brook University professor Heidi Hutner, recounts the saga about four housewives from Three Mile Island facing down the nuclear industry Goliath for over forty years, and The Grandson tells the story of a man’s refusal to allow heartless scammers to get the best of his grandfather in this tight Hungarian thriller.

There is no shortage of independent cinema in this year’s lineup, including the Serbian puzzle piece Where the Road Takes You, which takes the Western trope of the stranger in town who saves the girl and flips it on its head. From Canada comes the quirky comedy I Like Movies about the reformation of a crabby, awkward teenage cinephile. 

Also providing comic relief is the scenic and quietly riotous American indy Friends From Home, shot on the cheap during Covid, and from Italy, the strangely compelling Amanda, about a young woman who suddenly decides that an acquaintance from her very young childhood is now her best friend.

Rounding out a host of stellar independent offerings is the wild Yes, Repeat, No, set in a studio where three actors are all auditioning for the same role. This courageous and unforgettable film zeroes in on questions of conflicting identity while managing to surprise at every turn.

Some recognizable faces also show up in this year’s lineup, including Richard Kind, Karen Allen, and Peter Reigert in Hit Man: Secrets of Lies and the wickedly hilarious Two Chairs, Not One, starring Caitlin Reilly (HBO’s Hacks), whose wildly popular TikTok account has amassed hundreds of millions of views.

The closing night feature tells an extraordinary tale of overcoming. Divertimento shares the true story of sisters Zahia and Fettouma Ziouani, a conductor and a cellist, who, despite being Algerian immigrants from the wrong part of Paris, managed to create a world-class professional orchestra with little more than respect, determination, and sheer talent. Opening and closing with the insistent rhythm of Ravel’s Bolero, the film makes its hopeful message equally insistent: family and community can make the impossible possible.

“We are very excited to have filmmakers from all over the world join us for their premiere screenings. Our audiences can gather in a huge theater with Long Island’s largest screen, to see movies the way they were meant to be seen,” says Festival Director Alan Inkles. 

“Not only are these films not available on any streaming format, but you also get to hear directly from the filmmakers themselves, ask them a question at our live Q&A, and even vote for your favorite,” he said.

Additional sponsors for the Stony Brook Film Festival include Campolo, Middleton & McCormick, LLP; Suffolk County; Altice Media; and WLIW/PBS.

FILM SCHEDULE

OPENING NIGHT

Thursday, July 20 at 8 p.m.

Feature: Sea of Time

Short: The Red Suitcase

Friday, July 21 at 7 p.m.

Feature: Exodus

Short: Hit Friends

Friday, July 21 at 9:30 p.m.

Feature: I Like Movies

Short: Chipper

Saturday, July 22 at 7 p.m.

Feature: My Sailor, My Love

Short: The Countryman

Saturday, July 22 at 9:30 p.m.

Feature: Grandpa Goes South

Short: Two Chairs, Not One

Sunday, July 23 at 7 p.m.

Feature: Martha

Short: Stuck

Sunday, July 23 at 9:30 p.m.

Feature: Friends From Home.

Short: At A Glance

Monday, July 24 at 7 p.m.

Feature: Trapped Balloon

Short: Healer

Monday, July 24 at 9:30 p.m.

Feature: A Fleeting Encounter

Short: Winter’s Passing

Tuesday, July 25 at 7 p.m.

Feature: Elik & Jimmy

Short: The Third Defector

Tuesday, July 25 at 9:30 p.m.

Feature: Amanda

Short: Mahogany Drive

Wednesday, July 26 at 7 p.m.

Feature: Radioactive: The Women of Three Mile Island

Short: Queen Moorea

Wednesday, July 26 at 9:30 p.m.

Feature: Where the Road Leads

Short: Hit Man: Secrets of Lies

Thursday, July 27 at 7 p.m.

Feature: March ‘68

Short: The Father, The Son and The Rav Kalmenson

Thursday, July 27 at 9:30 p.m.

Feature: Yes Repeat No

Short: Demon Box

Friday, July 28 at 7 p.m.

Feature: The Grandson

Short: Death By Puppies

Friday, July 28 at 9:30 p.m.

Feature: First Snow of Summer

Short: Voices

CLOSING NIGHT

Saturday, July 29 at 8 p.m.

Feature: Divertimento

Short: The Basics of Love

CLOSING NIGHT AWARDS

10:30 p.m. Presented on stage.

——————————————-

Ticket information

All screenings are held at Stony Brook University’s Staller Center for the Arts, 100 Nicolls Road, Stony Brook in the 1,000-seat Main Stage theater. 

Festival goers can choose from a Gold Pass “VIP” ($250), Regular Pass ($100), new! Flex Pass ($75), or Individual Pass of $15, $13.50 seniors. To learn about the different membership levels and their benefits, call 631-632-2787 or visit www.stonybrookfilmfestival.com.

This article first appeared in Summer Times, a seasonal guide supplement by TBR News Media.

By Melissa Arnold

Spending any amount of time in a hospital setting is bound to be taxing, not just physically but emotionally. Sometimes, a little reminder that you’re being thought of and supported can make all the difference. 

Since 2008, the Stony Brook Stitchers have volunteered their time and skill to knit, crochet and sew gifts for patients that could use a pick-me-up.

Melissa Shampine

In the neonatal intensive care unit (NICU), families might receive a cute knit cap for their little one. In difficult situations where a baby passes away, a special wrap for the baby can be used to take treasured photos, and parents are given a memory pouch to hold mementos like a lock of hair. Patients in other departments, such as the cancer center or pediatric hospital, might curl up with an afghan, lap blanket or prayer shawl during their stay. Residents at the nearby Long Island State Veterans Home receive donations as well.

The project is a grassroots effort that began with hospital staff who wanted to brighten patients’ days.

Stitchers co-director Melissa Shampine grew up attending a small parochial school in Manhattan, where the boys were taught chess and the girls learned to crochet. 

“Even though it was mandatory, I found that I actually liked it, and eventually learned to knit as well,” she recalled. “I really enjoyed being creative in that way.”

Shampine now works as a teaching hospital staff assistant at Stony Brook University Hospital. One of her former coworkers, Shakeera Thomas, was also a knitter, and together they began to brainstorm ways they could use their talents to benefit patients.

The idea spread through word of mouth, first among hospital staff, then across the street to the university. Nurse directors and health care providers identified patients who might want a gift. Students and employees from both campuses began donating yarn and got to work. Their numbers grew, and over time, even the surrounding communities got involved.

Jan Tassie

While the project is united under the Stitchers title, there are no official members or meetings. Some people work together at their churches, libraries or other small group settings, but countless others simply knit at home when they have the time. 

In 2015, Jan Tassie responded to an email from Shakeera Thomas, inviting hospital employees to learn to crochet. 

“I always wanted to learn to crochet, and someone tried to teach me years ago when I was pregnant with my first son, but it didn’t work out,” said Tassie, who recently retired from the university’s Office of Financial Aid and Scholarship Services. “When I met Shakeera, she promised that when she was done with me, I’d be able to crochet. And at the end of one day, I could.”

Thomas relocated shortly thereafter, and Tassie stepped into the role as co-director for the Stitchers.

“In the hospital and university settings, you always have people who come and go, so the numbers wax and wane. But Jan is motivated — she is the kind of person who will chat up people in the yarn aisle at craft stores, or through networking, so there are always hands to help. Our website is a labor of love for her, too. She’s done so much,” Shampine said.

The Stitchers come from all walks of life and skill levels. Some have been knitting for decades, while others learned recently with the intent of supporting the project.

Among them is Jack Domaleski, a 24-year-old from New Suffolk who took up knitting during the pandemic quarantine.

Jack Domaleski with two knitted baby hats.

“During COVID, I taught myself to knit by watching videos on YouTube because I was bored and looking for something to do. It was easy to learn,” said Domaleski, who works in the restaurant industry. “My mom did it when I was younger, and it’s nice to end up with a finished product that you can share with others. I thought that it would be nice to donate to the hospital in some way, and when I wrote to them, they told me about the Stitchers.”

He was also inspired to knit by his own story. Domaleski was born several months premature, and spent nearly 90 days at Stony Brook’s NICU before he was strong enough to go home.

Today, he knits baby hats while thinking of other families going through similar circumstances.

“It helps me to feel connected to my own story, and anything you take the time to make is especially meaningful for the people that receive it,” he said. 

For information about volunteering or donating yarn or handmade items to the Stony Brook Stitchers, visit www.stonybrookstitchers.com or send an email to Jan Tassie at [email protected].

From left, Allison McLarty, MD, Marc Goldschmidt, MD, Hal Skopicki, MD, PhD. Photo from Stony Brook Medicine

In 2010, Stony Brook Heart Institute’s Ventricular Assist Device (VAD) Program was established on Long Island to implant this life saving device. A VAD, also often called a left ventricular assist device or LVAD, is a surgically implanted, battery powered pump that, by supporting the lower left ventricle (the heart’s main pumping chamber), helps a failing heart to do its job more efficiently. The VAD can be used as an intermediary step before heart transplantation or, in patients who, due to advanced age or medical condition are not transplant candidates, as a long-term “destination” device. 

VAD patient Joseph Cerqueira and his wife.

Now 10+ years later, patients, their families and medical staff from the Heart Institute gathered on June 15, to celebrate the anniversary of this life saving heart device and program. (The 10-year event was postponed in 2020 due to Covid-19.) 

“Nobody knew when we began putting in heart pumps 13 years ago that they would be this durable and reliable,” says Allison McLarty, MD, Surgical Director of the VAD program. “This amazing device has revolutionized the management of advanced heart failure.”  

“For the VAD team, there is the immense reward of seeing these extraordinary individuals return to their homes and families with a much better quality of life,” added Marc Goldschmidt, MD, Director, Heart Failure and Cardiomyopathy Center and Medical Director, Ventricular Device Program.

“A VAD program at Stony Brook Heart Institute has been a tremendous asset for both the community and the hospital. Patients with the most complex heart conditions have access right here, close to home, to all the state-of-the-art services they need,” said Hal Skopicki, MD, PhD, Co-Director, Stony Brook Heart Institute and Chief of Cardiology.  

Among the patients who attended today’s event was Joseph Cerqueira, 63, who received a VAD in 2017 and a heart transplant the following year. Following his surgery, Joseph returned to his work as a corporate chef. 

“Everybody went the extra mile to make me comfortable and knowledgeable on how to adapt to every aspect of life with a VAD,” said Cerqueira. “Now my quality of life is perfect. I still get tired and I know my limitations, but besides that I do whatever has to be done.”

To learn more about the Ventricular Assist Device Program, visit https://heart.stonybrookmedicine.edu/services/vad.

Benjamin Martin. Photo by Jeanne Neville/Stony Brook Medicine

Benjamin Martin, PhD, Associate Professor in the Department of Biochemistry and Cell Biology at Stony Brook University, and member of the Stony Brook University Cancer Center, has received a $2 million grant from the National Institutes of Health’s National Institute of General Medical Sciences (NIGMS) to conduct research to understand the molecular and cell biology of neuromesodermal progenitors. The grant term, effective June 1, 2023, is five years.

The Martin Lab uses zebrafish embryos as a model system. The grant enables Martin and colleagues to carry out research designed to more clearly define and observe neuromesodermal progenitors, stem cells that contribute to spinal cord or skeletal muscle development. The overall goal of the lab is to advance an understanding of the vertebrate body plan via the zebrafish embryos and provide insights to understand stem cell biology and mechanisms of cancer metastasis.

This image captured by the Martin lab shows three different time points of a developing zebrafish to demonstrate how differentiated neurons and muscle expand as the embryos grow. The image shows the zebrafish reporter transgenes that label skeletal muscle (magenta color) and neurons (green color). Image from Benjamin martin

Martin and colleagues observe zebrafish to demonstrate how differentiated neurons and muscle expand as embryos grow. Neuromesodermal progenitors exist in all vertebrate embryos, so zebrafish are used as a common model to these cells’ development to better define how the embryonic body plan is formed and how spinal cord and skeletal muscle are induced from this population.

Martin’s NIGMS grant is called the Maximizing Investigators’ Research Award (MIRA), under the category of supporting established scientific investigators. This distinction recognizes the importance of the lab’s research, and reinforces their efforts to reach a breakthrough in this area of cell biology.

NIGMS supports fundamental studies that shed light on biological processes and catalyze advancements in the diagnosis, treatment and prevention of diseases. It also leads efforts to train the next generation of scientists, promote diversity in the workforce, and expand research capacity nationwide.

 

 

From left, Dr. Richard Rugen, Chairman, WMHO; Gloria Rocchio, President, WMHO; Chris Richey, Trustee, WMHO; Dr. Taylor Evans, Stony Brook University School of Marine and Atmospheric Sciences; Kathleen Mich, Trustee, WMHO; Deborah Boudreau, Education Director, WMHO; Charles Napoli, Trustee, WMHO. In attendance virtually: Jamie Parker, The Fullwood Foundation; Nicole Sarno, Business Manager Director, Business Banking, Webster Bank; Jon Dilley, President, Mill River Wetland Committee. Not pictured: The Frey Family Foundation. Photo from WMHO

The Ward Melville Heritage Organization (WMHO) hosted its third Long  Island Sound Connections Summit last week. This virtual, hands-on collaborative learning program connects  students across Long Island Sound and allows them to conduct their own research to better understand the water  systems in their environment.  

Long Island Sound Connections is the first program to connect both shores with students from New York and  Connecticut — with virtual class check-ins, “summits” where students present their findings, an ongoing collection of  data, and an analysis on that information. The Long Island Sound Connections program was designed to help  students learn about the Long Island Sound and to inspire them to become ‘citizen scientists’ and protect their  environment. The program is offered via distance learning from the WMHO’s Erwin J. Ernst Marine Conservation  Center (EMCC), where students have front row seats to one of the most pristine natural resources in New York  State.  

Dr. Taylor Evans and WMHO Education Director Deborah Boudreau sharing information with classes about different species (such as horse shoe crabs) that have survived in the Long Island Sound, some for over 445 million years. Photo from WMHO.

WMHO collaborated with Stony Brook University’s Ecology and Evolution Distinguished Professor Jeffrey  Levinton, and Dr. Taylor Evans of Stony Brook University’s School of Marine and Atmospheric Sciences to  develop a system of data collection parameters for monitoring and analyzing West Meadow Creek’s water quality  and species counts. 

Professor Levinton and Dr. Evans will continue to support WMHO in developing this  multipronged project that seeks to educate the public by providing data representing the creek’s health over time to  the public and researchers. They will also assist participating classes to in continuing to learn about the Long Island  Sound environment on an ongoing basis.  

The third “summit” of classes in this program was between Ms. Michelle Miller and Ms. Doreen Barry’s 6th grade  Science class from Selden Middle School and Ms. Jess Castoro’s 6th grade Science class from Achievement First  Bridgeport Academy Middle School, who worked in collaboration with Mill River Wetland Committee. 

The 2023  “summit” participants have been researching the Sound for six months, and with assistance from professionals in the  field, have learned the environmental impact of industrialization, recent achievements on mitigating the effects, and  how to utilize their data in the future by monitoring the Sound. 

Each class created specialized newscasts to showcase  their findings on the relationships between water quality, animal and plant species, and even with human impact. In  this cross sectional study of the Sound, students compared and contrasted their two environments (suburban and  urban) and presented it to their partner class. 

In addition, the study is longitudinal and seeks to track changes over  time. Data will be added into the WMHOs software to create a data map and timeline to assist environmental  researchers of all ages to understand and appreciate similarities and differences across the Long Island Sound.  

With grants provided by the Fullwood Foundation, the Frey Family Foundation and Webster Bank, this program  was offered to participating classes free of charge. All costs associated with the program were sponsored by these  organizations.  

For more information about the WMHO, on the Long Island Sound Connection program, other historic,  environmental and scientific programs that the WMHO offers, please call 631-751-2244 or visit wmho.org. 

Ali Khosronejad in front of the Santa Maria Cathedral, which is considered the first modern cathedral in Madrid.

By Daniel Dunaief

An approaching weather front brings heavy rains and a storm surge, threatening to inundate homes and businesses with dangerous water and potentially undermining critical infrastructure like bridges.

Once officials figure out the amount of water that will affect an area, they can either send out inspectors to survey the exact damage or they can use models that take time to process and analyze the likely damage.

Ali Khosronejad

Ali Khosronejad, Associate Professor in the Department of Civil Engineering at Stony Brook University, hopes to use artificial intelligence to change that.

Khosronejad recently received $550,000 from the National Science Foundation (NSF) for four years to create a high-fidelity model using artificial intelligence that will predict the flood impact on infrastructure.

The funds, which will be available starting on June 20, will support two PhD students who will work to provide an artificial intelligence-based program that can work on a single laptop at a “fraction of the cost of more advanced modeling approaches,” Khosronejad said during an interview in Madrid, Spain, where he is on sabbatical leave under a Fulbright U.S Senior Scholar Award. He is doing his Fulbright research at Universidad Carlos III de Madrid.

Stony Brook University will also provide some funding for these students, which will help defray the cost of expenses related to traveling and attending conferences and publishing papers.

In the past, Stony Brook has been “quite generous when it comes to supporting graduate students working on federally funded projects,” Khosronejad explained and he hopes that continues with this research.

Khosronejad and his students will work with about 50 different flooding and terrain scenarios, which will cover about 95 percent of extreme flooding. These 50 possibilities will cover a range of waterways, infrastructure, topography, and coastal areas. The researchers will feed data into their high fidelity supercomputing cluster simulations to train artificial intelligence to assess the likely damage from a flood.

As they build the model, Khosronejad explained that they will collect data from floods, feed them into the computer and test how well the computer predicts the kind of flooding that has can cause damage or threaten the stability of structures like bridges. Over the next four years, the team will collect data from the Departments of Transportation in California, Minnesota and New York.

Nearly six years ago, his team attempted to use algorithms available in ChatGPT for some of his AI development. Those algorithms, however, didn’t predict flood flow prediction. He tried to develop new algorithms based on convolutional neural networks. Working with CNN, he attempted to improve its capabilities by including some physics-based constraints.

“We are very enthusiastic about this,” Khosronejad said. “We do think that this opportunity can help us to open up the use of AI for other applications in fluid mechanics” in fields such as renewable energy, contaminant transport predictions in urban areas and biological flow predictions, among others.

Planners working with groups such as the California Department of Transportation could use such a program to emphasize which infrastructure might be endangered.

This analysis could highlight effective mitigation strategies. Artificial intelligence can “provide [planners and strategists] with a tool that is not that expensive, can run on a single laptop, can reproduce lots of scenarios with flooding, to figure out which infrastructure is really in danger,” Khosronejad said.

Specifically, this tool could evaluate the impact of extreme floods on bridge foundations. Floods can remove soil from around the foundation of a bridge, which can cause it to collapse. Civil engineers can strengthen bridge foundations and mitigate the effect of future floods by using riprap, which is a layer of large stones.

This kind of program can reduce the reliance on surveying after a flood, which is expensive and sometimes “logistically impossible and unsafe” to monitor areas like the foundations of bridges, Khosronejad said. He plans to build into the AI program an awareness of the changing climate, so that predictions using it in three or five years can provide an accurate reflection of future conditions.

“Floods are getting more and more extreme” he said. “We realize that floods we feed into the program during training will be different” from the ones that will cause damage in subsequent years.

Floods that had a return period of every 100 years are now happening much more frequently. In one or two decades, such a flood might occur every 10 years.

Adding updated data can allow practitioners to make adjustments to the AI program a decade down the road, he suggested. He and his team will add data every year, which will create a more versatile model.

What it can’t do

While the AI programs will predict the damage to infrastructure from floods, they will not address storm or flood predictions.

“Those are different models, based on the movement of clouds” and other variables, Khosronejad said. “This doesn’t do that: if you give the program a range of flood magnitudes, it will tell you what will happen.”

High fidelity models currently exist that can do what Khosronejad is proposing, although those models require hundreds of CPUs to run for five months. Khosronejad has developed his own in house high fidelity model that is capable of making similar predictions. He has tested it to examine various infrastructures and used it to study various flooding events. These models are expensive, which is why he’s trying to replace them with AI to reduce the cost while maintaining fidelity.

AI, on the other hand, can run on a single CPU and may be able to provide the same result, which will allow people to plan ahead before it happens. The NSF approved the single principal investigator concept two months ago.

Khosronejad has worked with Fotis Sotiropoulos, former Dean of the College of Engineering and Applied Sciences at Stony Brook and current Provost at Virginia Commonwealth University, on this and other projects.

The two have bi-weekly discussions over the weekend to discuss various projects.

Sotiropoulos was “very happy” when Khosronejad told him he received the funds. Although he’s not a part of the project, Sotiropoulos will “provide inputs.”

Sotiropoulos has “deep insights” into fluid mechanics. “When you have him on your side, it always pays off,” Khosronejad said.

Dr. Justice Achonu. Photo by Jeanne Neville/ Stony Brook Medicine

Justice Achonu, MD, an orthopaedic surgery resident at Stony Brook Medicine, is one of four orthopaedic surgeons in the U.S. to be selected for the American Board of Orthopaedic Surgery’s (ABOS) Resident Advisory Panel. Responsible for providing insight into the resident experience, the panel collaborates with multiple other committees within the ABOS to support the interests of residents throughout the country. His two-year term on the panel begins July 1, 2023.

According to the ABOS, each applicant to the panel is reviewed by at least two ABOS Board members who are all accomplished leaders in their field. Applicants practice in all regions of the country. Dr. Achonu’s panel cohort is the third ever selected by the ABOS. Every year, the panel is tasked with identifying and completing a project that will benefit orthopaedic residents across more than 200 accredited training programs nationwide.

Panelists are encouraged to provide the ABOS with recommendations, several of which have been adopted by the Board, including an official Residency to Retirement Roadmap.

Dr. Achonu received a B.S. in neuroscience from the University of Pittsburgh in 2015 and graduated from the Renaissance School of Medicine at Stony Brook University in 2020. He resides in Holbrook.

Stony Brook’s Department of Orthopaedics provides full-service patient care and sub-specialty resident and faculty training in all areas of Orthopaedics. The department includes a comprehensive Orthopaedic Research Program featuring clinical and laboratory facilities and resources for investigation of molecular, biologic, and biomechanical research topics.

Speakers at the “Africa: The Human Cradle" International Conference paying Tribute to Richard E. Leakey” on June 5. Photo by John Griffin/Stony Brook University

By Daniel Dunaief

Combative, loyal, determined, consequential, energetic and courageous. These are just a few of the many traits paleoanthropologists and others shared to describe the late Richard Leakey at the “Africa: The Human Cradle” memorial conference at Stony Brook University this week.

The founder of the Turkana Basin Institute in Kenya, Leakey, who partnered with SBU and received 34 grants from National Geographic over the course of his decades in science, was a part of nearly every presentation and discussion on the first day of the week-long event which closes tomorrow, June 9.

From left, Stony Brook University President Maurie McInnis with Louise Leakey on June 5. Photo by John Griffin/Stony Brook University

Held at the Charles B. Wang Center on the main campus, the conference brought together luminaries in the field who interlaced stories about their science in Africa with anecdotes — many of them humorous — about Leakey. Marilyn and Jim Simons, whose Simons Foundation announced last week that it was donating $500 million to the university, attended the entire slate of speakers on the first day.

Leakey was “one of the most important paleoanthropologists of our time,” Maurie McInnis, President of Stony Brook, said in opening remarks. His impact “can be felt across our campus and across the world.”

In an interview, former Stony Brook President Shirley Kenney, who helped bring Leakey to the university, suggested that he “put us into the elite of that whole research field.”

Leakey stubbornly entered his parents Mary and Louis’s chosen fields when he dropped out of high school, eager to make discoveries on his own and to contribute to his native Kenya.

In 1968, during a meeting at the National Geographic headquarters, Leakey “lobbied the committee to divert funding from his father’s money” to his own research, Jill Tiefenthaler, National Geographic CEO, said during her presentation.

‘Sitting on a knife edge’

Like Leakey, however, these scientists looked deep into the past to understand the lives of early humans, our distant ancestors and other organisms while looking for lessons that might help with the present and the future.

Dino Martins, Chief Executive Officer of the Turkana Basin Institute and Lecturer in the Department of Ecology & Evolutionary Biology, suggested that Leakey was driven by a sense of “childlike wonder” and a need to know “where we are, where we’re coming from and where we’re going.”

Leakey suggested that the extremely hot climate in Kenya was a potential model to understand how ancestral humans survived in hotter conditions, which are becoming increasingly prevalent amid global warming.

“There are many parallels in the past” in terms of extreme environments, Louise Leakey, director of public education and outreach for the Turkana Basin Institute and Richard and Meave Leakey’s daughter, said in an interview. “We’re sitting on this knife edge of really dramatic change now.” 

In addition to encouraging science in Africa, Leakey also believed in engaging with students and researchers from a range of backgrounds and experiences. He wanted to ensure that people from every continent had an opportunity to join the ranks of scientists.

When presenting his research on Homo naledi, an extinct human with a brain a third the size of modern humans from South Africa who created burial sites and left behind etchings on a cave wall, Lee Berger, National Geographic Explorer in Residence, explained that he wished Leakey “had seen this and I think he would have been really angry with me.”

Words from a devoted daughter

In the final presentation of the first day, Louise Leakey shared memories of her upbringing and her father.

Among many pictures of her father and his discoveries over the years, Louise shared one in which she highlighted a pipe in the corner of the photo.  She believed her father “rarely smoked it” but liked to pose with it in photos.

Louise Leakey speaks at the memorial conference for her father on June 5. Photo by John Griffin/Stony Brook University

Louise Leakey recalled how one of her father’s partners, Kamoya Kimeu, proved a valuable partner in the search for fossils. When Kimeu died soon after Richard Leakey, Kimeu’s daughter Jennifer reached out to Louise to raise money for his funeral.

Louise Leakey has since learned that Jennifer never saw her father searching for fossils in the field. Rather, she learned all about his exploits when her mother read his letters each night to her before she went to bed.

A second generation of the two families is working together, as Jennifer has joined Louise in some of her fossil hunting work. The two daughters are also creating a comic strip, in many languages, that depicts the two of them hunting for fossils.

Leakey believes Jennifer Kimeu will serve as an inspiration to other Kenyans.

On the east side of Lake Turkana, Leakey and her team recently discovered the new head of a fossil. Before his death, her father said it was “time you found new skull.” Richard Leakey was right.

Chengfeng Yang Photo by Zhishan Wang

By Daniel Dunaief

This is part two of a two-part series.

As Erin Brockovich (the real life version and the one played by Julia Roberts in the eponymous movie) discovered, some metals, such as hexavalent chromium can cause cancer in humans.

Chengfeng Yang and Zishan Wang

Environmental exposure to a range of chemicals, such as hexavalent chromium, benzo(a)pyrene, arsenic, and others, individually and in combination, can lead to health problems, including cancer.

In March, Stony Brook University hired Chengfeng Yang and Zhishan Wang, a husband and wife team to join the Cancer Center and the Pathology Departments from Case Western Reserve University.

The duo, who have their own labs and share equipment, resources and sometimes researchers, are seeking to understand the epigenetic effect exposure to chemicals has on the body. Yang focuses primarily on hexavalent chromium, while Wang works on the mechanism of mixed exposures.

Last week, the TBR News Media highlighted the work of Wang. This week, we feature the work of Yang.

————————————–

When he was young, Chengfeng Yang was using a knife to make a toy for his younger brother. He slipped, cutting his finger so dramatically that he almost lost it. Doctors saved his finger, impressing him with their heroic talent and inspiring him to follow in their footsteps.

Indeed, Yang, who earned an MD and a PhD from Tongji Medical University, is focused not only on answering questions related to cancer, which claimed the life of his mother and other relatives, but also in searching for ways to develop new treatments.

A Professor in the Department of Pathology at the Renaissance School of Medicine at Stony Brook University and a member of the Stony Brook Cancer Center, Yang has his sights set on combatting cancer.

“Our research always has a significant clinical element,” said Yang. “This is related to our medical background.”

He is interested in studying the mechanism of cancer initiation and progression and would like to develop new strategies for treatment.

Yang and his wife Zhishan Wang recently joined the university from Case Western after a career that included research posts at the University of Pennsylvania, Michigan State University, and the University of Kentucky.

The tandem, who share lab resources and whose research staffs collaborate but also work independently, are focused specifically on the ways exposures to carcinogens in the environment cause epigenetic changes that lead to cancer.

Specifically, Yang is studying how hexavalent chromium, a metal commonly found in the environment in welding, electroplating and even on the double yellow lines in the middle of roads, triggers cancer. It is also commonly used as a pigment to stain animal leather products.

Yang is focused mainly on how long cancer develops after exposure to hexavalent chromium.

People can become exposed to hexavalent chromium, which is also known as chromium 6, through contaminated drinking water, cigarette smoking, car emissions, living near superfund sites and through occupational exposure.

Yang has made important findings in the epigenetic effect of metal exposure. His studies showed that chronic low-level chromium six exposure changed long non-coding RNA expression levels, which contributed to carcinogenesis. Moreover, his studies also showed that chronic low level exposure increased methylation, in which a CH3 group is added to RNA, which also contributed significantly to chromium 6 carcinogenesis.

“It is now clear that metal carcinogens not only modify DNA, but also modify RNA,” Yang explained. Metal carcinogen modification of RNAs is an “exciting and new mechanism” for understanding metal carcinogenesis.

By studying modifications in RNA, researchers may be able to find a biomarker for the disease before cancer develops.

Yang is trying to find some specific epigenetic changes that might occur in response to different pollutants.

Stony Brook attraction

Yang was impressed with the dedication of Stony Brook Pathology Chair Ken Shroyer, whom he described as a “really great physician scientist. His passion in research and leadership in supporting research” helped distinguish Stony Brook, Yang said.

Yang is confident that Stony Brook has the resources he and Wang need to be successful, including core facilities and collaborative opportunities. “This is a very great opportunity for us, with strong support at the university level,” he said.“We plan to be here and stay forever.”

Yang is in the process of setting up his lab, which includes purchasing new equipment and actively recruiting scientists to join his effort.

“We need to reestablish our team,” he said. “Right now, we are trying to finish our current research project.”

He hopes to get new funding for the university in the next two to three years as well. After he establishes his lab at Stony Brook, Yang also plans to seek out collaborative opportunities at Cold Spring Harbor Laboratory, which is “very strong in RNA biology,” he added.

A return home

Returning to the Empire State brings Yang full circle, back to where his research experience in the United States started. About 23 years ago, his first professional position in the United States was at New York University.

Outside of work, Yang likes to hike and jog. He is looking forward to going to some of Long Island’s many beaches.

He and Wang live in an apartment in South Setauket and are hoping to buy a house in the area. The couple discusses science regularly, including during their jogs.

Working in the same area provides a “huge opportunity” for personal and professional growth, he said.

Yang suggested that his wife usually spends more time training new personnel and solving lab members’ technical issues. He spends more time in the lab with general administrative management and support. Wang has “much stronger molecular biology skills than I have,” Yang explained in an email, whereas he has a solid background in toxicology.

Growing up, Yang said he had an aptitude in math and had dreamed of becoming a software engineer. When he applied to college, he received admission to medical school, which changed his original career path.

Once he started running his own experiments as a researcher, he felt he wanted to improve human health.“Once humans develop disease, in many cases, it’s very expensive to treat and [help] people recover,” he said. “Prevention could be a more cost effective way to improve health.”

Stony Brook University: Entrance sign

The Simons Foundation’s contribution is the largest unrestricted endowment gift to a higher education institution in American history

The Simons Foundation, a philanthropy working to advance the frontiers of research in mathematics and the basic sciences, today announced a historic $500 million endowment gift to Stony Brook University during a news conference at the foundation’s Manhattan headquarters. This monumental gift — the combined largesse of the Simons Foundation and Simons Foundation International — is the largest unrestricted donation to an institution of higher education in U.S. history.

The extraordinary gift is also expected to grow by up to $1 billion in contributions for Stony Brook University’s endowment by capitalizing on New York State’s 1:2 endowment matching program and other philanthropy inspired by this gift. This transformative donation will cement Stony Brook’s place as New York’s flagship research institution and provide the means to invest in areas most urgent and necessary to help sustain the university’s commitment to educational excellence, research innovation and community support.

Investments stemming from this gift will have a direct and positive impact on perpetual funding for student scholarships, endowed professorships, innovative research, and excellent clinical care.

“The Simons Foundation mission is to advance the frontiers of research in mathematics and the basic sciences,” Foundation President David Spergel said. “For more than a decade, we have been proud to give to an institution that is at the forefront of educational excellence in the sciences. It is our sincere hope that this large unrestricted gift will build upon our previous support to Stony Brook, giving students and faculty the ability to dream big and engage in transformative research.”

“A world-class, public education has the ability to transform the lives of New Yorkers, which is why in this year’s budget we created the first-ever matching fund for endowment contributions for SUNY’s university centers,” Governor Kathy Hochul said. “Time and again, Stony Brook University forges a bold path forward, from innovation happening at Brookhaven Lab to the economic development throughout Long Island. With this remarkable contribution from the Simons Foundation, Stony Brook will continue to excel as an internationally recognized research institution and give students the tools they need to succeed.”

“We are eternally grateful to Jim and Marilyn Simons and Simons Foundation President David Spergel for their unparalleled support of Stony Brook University. In 1960, we were given a mandate by the State Board of Regents to become a university that would ‘stand with the finest in the country,’” University President Maurie McInnis said. “Thanks in large part to the generosity of the Simons Foundation, we have done just that, and we have no intention of slowing down. We take seriously our commitment to our students, our faculty and our broader community to advance knowledge and contribute to the most significant challenges facing our society. We are so proud of all that we have accomplished as an institution and our best days are ahead of us.”

“I joined Stony Brook University in 1968 as Chair of their Department of Mathematics,” Simons Foundation Co-Founder Jim Simons said. “I knew then it was a top intellectual center with a serious commitment to research and innovation. But Stony Brook also gave me a chance to lead — and so it has been deeply rewarding to watch the university grow and flourish even more. Marilyn and I are proud to support this outstanding public university that has given us so much.”

“As a Stony Brook graduate, I know firsthand the role that a quality education plays in the trajectory of one’s life,” said Marilyn Simons ’74, PhD ’84, Simons Foundation Co-Founder. “I am proud of the education I received there. Jim and I want to ensure that Stony Brook continues to serve its students with the highest level of educational excellence and with world-class resources. The foundation’s gift will also help give those from underserved communities the opportunity to reach their full potential. We look forward to seeing this institution continue to thrive.”

Since Jim and Marilyn made their first gift of $750 in 1983, they and the Simons Foundation have committed more than $1.2 billion to Stony Brook, while also inspiring over 2,100 other donors to give to the university. Their transformational support has led to growth impacting every corner of the Stony Brook campus and beyond, from the Renaissance School of Medicine and the Simons Center for Geometry and Physics to Stony Brook’s Simons STEM Scholars program, nine endowed chairs and professorships in economics, and more.

In addition to this historic gift and previous gifts to Stony Brook University, last month, following Stony Brook’s successful bid to serve as the anchor institution of the The New York Climate Exchange, the Simons Foundation committed $100 million to the project’s expected $700 million budget. These funds will help establish this climate research, education and green-economy training hub, set to transform how the world responds to the climate crisis and pioneer investigation into environmental, community and health outcomes and impacts.

The Simons’ own personal involvement in Stony Brook community life over the past 55 years has been life-changing for generations of students’ and scholars’ past, present and future. They have provided countless hours of counsel and leadership to advance important initiatives. For example, Marilyn Simons’ work with the  Stony Brook Women’s Leadership Council mentoring program has been a launchpad for the careers of many undergraduates from all over campus.

“Jim and Marilyn have a long history of generously supporting the sciences, education, and the health and well-being of New Yorkers,” said Michael R. Bloomberg, founder of Bloomberg LP and Bloomberg Philanthropies, and 108th Mayor of New York City. “This new gift is an extraordinary example of that, and it will help Stony Brook University make critical investments that will empower more students to reach their full potential.” 

“The generosity of Jim and Marilyn Simons and the Simons Foundation has already changed the lives of millions of New Yorkers, and this historic contribution to Stony Brook University will impact our students and our state for generations to come,” said SUNY Chancellor John B. King Jr. “Today’s announcement will benefit SUNY students through scholarship, academic programs, and research opportunities, and it will enhance Stony Brook’s prominence as a world-class leader of higher education. The Simons donation illustrates the power of Governor Hochul’s Endowment Fund Match program to multiply the support of generous donors to expand research and scholarship across SUNY.”

“It is my true honor to know Jim and Marilyn and to have had the privilege to work alongside them for more than 30 years,” said Stony Brook Foundation Board of Trustees Chair Richard Gelfond ‘76. “Both as an alumnus of Stony Brook and as Board chair, I am grateful for their generous philanthropic support, their leadership, and their friendship. They have made an indelible impact on the future of the University.”

# # #

About Stony Brook University

Stony Brook is New York’s top ranked public university and a part of the State University of New York (SUNY) system, an internationally recognized research institution and center of academic excellence dedicated to addressing pressing global challenges. SBU serves as the anchor institution for the New York Climate Exchange on Governors Island, the nation’s first climate research, education and green-sector-job-training hub set to transform how our global response to the climate crisis. As one of only eight American universities with a role in running a national laboratory, Stony Brook is also the joint managing partner of the Brookhaven National Laboratory for the U.S. Department of Energy.  The university’s distinguished faculty have earned esteemed awards such as the Nobel Prize, Pulitzer Prize, Indianapolis Prize for animal conservation, Abel Prize and the inaugural Breakthrough Prize in Mathematics.

 

About Simons Foundation

Co-founded in 1994 in New York City by Jim and Marilyn Simons, the Simons Foundation’s mission is to support basic scientific research in pursuit of understanding the phenomena of our world. The Simons Foundation provides grants to individual researchers and to scientific collaborations and institutions, work in mathematics and physical sciences, life sciences, neuroscience, and autism science. The Simons Foundation also conducts computational research in basic sciences in-house at its Flatiron Institute.