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By Michael Christodoulou

Michael Christodoulou
Michael Christodoulou

As you know, 2021 was full of challenges. We were still feeling the effects of the COVID-19 pandemic when supply chains shut down and inflation heated up. So, if you’re like many people, you might not be sorry to see the year come to a close. But now it’s time to look ahead to 2022. And on a personal level, you may want to set some New Year’s resolutions. You might resolve to improve your health and diet, and possibly learn some new skills, but why not make some financial resolutions, too?

Here are a few ideas to consider:

Prepare for the unexpected. If you haven’t already created an emergency fund, now may be a good time to start. Ideally, you’d like to have three to six months’ worth of living expenses in this fund, with the money kept in a low-risk, liquid account. (If you’re retired, you may want your emergency fund to contain up to a year’s worth of living expenses.) Once you’ve got this fund established, you may be able to avoid dipping into long-term investments to pay for short-term needs, such as costly home or auto repairs or large medical bills.

Boost your retirement savings. The pandemic caused many us to reevaluate our ability to eventually enjoy the retirement lifestyles we’ve envisioned. In fact, 33% of those planning to retire soon said they started to contribute even more to their retirement savings during the pandemic, according to a study from Age Wave and Edward Jones. This year, if you can afford it, increase your contributions to your IRA and your 401(k) or other employer-sponsored retirement plan.

Reduce your debt load. The less debt you carry, the more money you’ll have available to support your lifestyle today and save and invest for tomorrow. So, this year, resolve to cut down on your existing debts and avoid taking on new ones whenever possible. You can motivate yourself by measuring your progress – at the beginning of 2022, record your total debts and then compare this figure to your debt load at the start of 2023. If the numbers have dropped, you’ll know you were making the right moves.

Don’t overreact to the headlines. A lot can happen during a year. Consider inflation – it shot up in 2021, but it may well subside in 2022. If you changed your investment strategy last year to accommodate the rise in inflation, would you then have to modify it again when prices fall? And inflation is just one event. What about changes in interest rates? How about new legislation coming out of Washington? And don’t forget extreme weather events, such as wildfires and floods. 

Any or all of these occurrences can affect the financial markets in the short term, but it just doesn’t make sense for you to keep changing the way you invest in response to the news of the day. Instead, stick with a strategy that’s appropriate for your goals, risk tolerance and time horizon. You may need to adjust this strategy over time, in response to changes in your own life, but don’t let your decisions be dictated by external events. 

These aren’t the only financial resolutions you can make – but following them may help you develop positive habits that can help you face the future with confidence.

Michael Christodoulou, ChFC®, AAMS®, CRPC®, CRPS® is a Financial Advisor for Edward Jones in Stony Brook. Member SIPC.

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By Nancy Burner, Esq.

Nancy Burner, Esq.

Whether your trust requires its own EIN depends on the type of trust that you have. An Employer Identification Number (“EIN”) is a nine-digit number that the Internal Revenue Service (“IRS”) assigns to identify an entity for tax reporting purposes. An EIN, also known as a federal tax ID number, functions like a social security number.

Generally, revocable trusts do not need an EIN as they are grantor trusts and the trust’s income is reported on the tax return of the trust creator. If you have created a revocable trust, you may revoke the trust at any time and “regain” possession of the trust assets. Accordingly, a revocable trust is an extension of the grantor who created the trust. The grantor pays the income taxes generated by the revocable trust and uses the social security number of its grantor as its tax ID. Couples with a joint revocable trust both hold the power to revoke the trust, either person’s social security number can be used. A separate tax ID is necessary if they do not file taxes jointly.

A revocable trust becomes irrevocable at the grantor’s death. At that time, the trust requires an EIN, as the trust can no longer be associated with the deceased grantor’s social security number. The trust must file its own taxes.

Some lifetime irrevocable trusts are also grantor trusts and therefore taxed to the grantor just like a revocable trust. While it is not required for these trusts to maintain a separate tax ID, it is sometimes a good idea to assign same. We usually assign a federal tax ID when we do Medicaid Asset Protection Trusts. If an irrevocable trust is not classified as a grantor trust, an EIN is required as the trust is considered a “separate entity” from the grantor.

If your trust requires an EIN, an application is submitted to the IRS as soon as possible. The application contains information from the grantor and the trust to answer a series of questions for the IRS. A trustee can either apply online, or mail/fax IRS Form SS-4. If a trustee applies online, the EIN is available in a matter of minutes. If the application is completed by fax or mail, it may take a few weeks to receive the EIN.

Discuss any questions relating to the need of a separate tax ID for your trust with an experienced estate planning attorney or tax advisor. Since the income tax rate for a trust is usually so much higher than that for an individual, the question of how your trust is taxed is an crucial consideration when considering trusts.

Nancy Burner, Esq. practices elder law and estate planning from her East Setauket office. Visit www.burnerlaw.com.

By Cayla Rosenhagen

Cayla Rosenhagen

What do you get when you combine a fun, learning experience full of incredible creatures with a festive, homemade craft fair? Magic and fun for the whole family!

The festival took place at Sweetbriar Nature Center in Smithtown on December 4. I arrived with my family a little after dusk, eager to see the rescue animals and browse the tents full of artwork and handicrafts. Vendors’ booths were spread out across the lawn, sparkling with colorful fairy lights and candles, and decked with festive garlands. 

Smiling festival-goers walked around sipping hot chocolate, visiting the shops, and meeting the ambassador animals, accompanied by friendly and knowledgeable Sweetbriar volunteers. The upbeat music of local ska and pop-punk cover band Crisis Crayons contributed to the cheerful atmosphere.

Many of the vendors I met with sold nature-related goods and artwork. For instance, Audra Donroe is an art teacher and creator from Northport. Her vibrant and stunning display of work ranged from original artwork and prints to postcards and ornaments utilizing natural imagery such as owls and plant life. She grew up coming to Sweetbriar and has been vending for 4 years. “Any chance I have to bring awareness and support to Sweetbriar, I gladly do it,” she says.

I also visited a booth selling organic, homemade elderberry syrup. It was run by the business’s founders, Connor and Tommy, aged 7 and 9, and their parents. I spoke with their mother, Michelle Biddle, who explained that elderberry is a natural remedy for cold and allergy symptoms.  

Other vendors included Once Upon A Favor, who were selling irresistibly aromatic bath bombs, soaps, and candles, and Beast Makers, who sold one-of-a-kind jewelry and occult items made out of ethically sourced animal bones and antlers.

Throughout the event, volunteers from the Center gave presentations about some of the animals who are permanent residents there. Guests met Opal the Virginia Opossum, Seven of Nine the Barred Owl, Stitch the Red-tailed Hawk, Nebula the Barn Owl, and more. Sweetbriar provides care for over 100 animals.  For many of them, Sweetbriar is their forever home as they cannot be released back into the wild due to their injuries.

According to Sweetbriar’s program coordinator, Veronica Sayers, the Holiday Party is an annual event that has taken place for around 40 years. Veronica explained that vendors pay a fee to take part in the event, and the proceeds go towards food and other vital resources for the animals Sweetbriar rehabilitates and cares for.

The event itself was free for visitors, although donations were appreciated. If you are interested in donating to help support the Center’s work and the animals in their care, please see their website for more details on how to do so. Other ways to show your support include spreading the word about Sweetbriar and attending their upcoming events. These include the Owl Prowl on December 9, weekly yoga classes, and the Superheroes of the Sky raptor event on January 1st.

Come visit Sweetbriar and be mesmerized by the incredible animals yourself! The Nature Center and Preserve at 62 Eckernkamp Drive in Smithtown are open daily from 9 a.m. to 4:30 p.m. For more information, please call 631-979-6344 or visit sweetbriarnc.org.

Cayla Rosenhagen is a local high school student who enjoys capturing the unique charm of the community through photography and journalism. She serves on the board of directors for the Four Harbors Audubon Society and Brookhaven’s Youth Board, and is the founder and coordinator of Beach Bucket Brigade, a community outreach program dedicated to environmental awareness, engagement, and education. She is also an avid birder, hiker, and artist who is concurrently enrolled in college, pursuing a degree in teaching.

Whisper

MEET WHISPER!

Whisper

This week’s shelter pet is Whisper, a 7 to 8-month-old medium haired bundle of fur currently up for adoption at the Smithtown Animal Shelter.

At first, Whisper seems like a shy cat, but once she trusts you, she is affectionate and sweet. She would do well in a quiet and calm home. This sweetheart spends most of her day hiding, but when she interacts with people and cats, she is friendly. She would likely also do well with a calm and gentle dog.

If you would like to meet Whisper, please call ahead to schedule an hour to properly interact with them in a domestic setting.

The Smithtown Animal & Adoption Shelter is located at 410 Middle Country Road, Smithtown. Shelter operating hours are currently Monday to Saturday from 10 a.m. to 3 p.m. (Sundays and Wednesday evenings by appointment only). Call 631-360-7575 or visit www.smithtownanimalshelter.com.  

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By Barbara Beltrami

The candy cane, that red and white Christmas phenomenon, as emblematic of the holiday as Santa and his reindeer or bauble-festooned evergreens, is one of my favorite ingredients when creating holiday confections. Its cool peppermint flavor echoes the air outside and its  sweetness appeals to kids and grownups alike. Candy cane meringue kisses and fingerprint cookies make lovely treats for wrapping up as gifts or swapping at cookie exchanges while a candy cane cheesecake with a chocolate crust combines three winning flavors in one beautiful dessert. So go ahead, swipe a few candy canes from the tree and start baking.

Candy Cane Meringue Kisses

Candy Cane Meringue Cookies

YIELD: Makes about 3 dozen

INGREDIENTS: 

2 large egg whites at room temperature

1/8 teaspoon cream of tartar

1/8 teaspoon fine salt

1/2 cup sugar

2 candy canes, finely crushed

DIRECTIONS: 

Preheat oven to 225 F. Line baking sheets with parchment. Put egg whites in large bowl and add cream of tartar and salt; beat until foamy. Add sugar, one tablespoon at a time, beating on high after each addition; continue beating until stiff, glossy peaks form. Transfer mixture to piping bag and pipe 1 1/2” cookies 2 “ apart onto parchment; sprinkle evenly with crushed candy canes and bake 1 1/2 to 2 hours until firm but not brown; transfer to wire racks to cool; store in airtight container.  Serve with peppermint tea or hot chocolate.

Candy Cane Fingerprint Cookies

Stock photo

YIELD: Makes about 4 dozen

INGREDIENTS: 

48 candy cane kisses

4 – 5 candy canes, finely crushed

1 cup unsalted butter, at room temperature

1 cup sugar

1 large egg at room temperature

1 tablespoon milk

1 teaspoon vanilla extract

3 cups flour

2 teaspoons baking powder

1/4 teaspoon salt

DIRECTIONS: Place candy kisses in a covered container and freeze for at least one hour. Preheat oven to 350 F. Line baking sheets with parchment. In a large bowl cream butter and sugar until light and fluffy; beat in egg, milk and vanilla. In another large bowl sift together flour, baking powder and salt; gradually beat into other mixture. Shape into one-inch balls and roll each one in crushed candy canes; place two inches apart on parchment and bake 10 to 12 minutes, until bottoms are golden brown. Remove from oven and immediately make an indentation with your finger and press a candy cane kiss into center of each cookie. Transfer to wire racks. Serve with egg nog or Irish coffee.

Candy Cane Cheesecake

YIELD: Makes 12 to 16 servings

INGREDIENTS: 

2 1/2 cups crumbled chocolate wafers

1/3 cup unsalted butter, melted

Six 8-ounce packages cream cheese, softened

1 1/3 cups sugar

1 cup sour cream

3 tablespoons flour

1 tablespoon vanilla extract

1 teaspoon peppermint extract

3 large eggs, lightly beaten

10 ounces chocolate chips

12 ounces heavy cream, whipped

4 candy canes, crushed

DIRECTIONS: 

Preheat oven to 325 F. Grease a 9” springform pan, then tightly wrap the outside with two layers of aluminum foil. In a small bowl combine chocolate wafers and melted butter and press mixture into bottom and one inch up sides of pan; set on a rimmed baking sheet and bake 12 to 15 minutes, until set; cool on wire rack.  

In a large bowl beat 5 of the packages of cream cheese with one cup of the sugar until smooth; beat in sour cream, flour and extracts; add eggs and beat on low speed just until combined; fold in chocolate chips, then pour mixture into chocolate crust. Place pan in roasting pan to which one inch hot water has been added. Bake 1 1/4 to 1 1/2 hours, until center is set and top is no longer shiny. Cool on wire rack 30 minutes; run knife around edge to loosen cake, then cool one hour longer; refrigerate overnight, then remove sides of pan. 

For the topping, beat together remaining 8 ounces cream cheese and one-third cup sugar until smooth; fold in whipped cream and 3/4 of the crushed candy canes.  Spread mixture over top of cake; sprinkle remaining candy canes on top.  Refrigerate until ready to serve. Serve with peppermint schnapps.

By Daniel Dunaief

Daniel Dunaief

Before each game, the Stony Brook University women’s basketball team meditates.

The pre-game ritual, among other changes and additions first-year Coach Ashley Langford instituted, has worked, as the team has a 7-1 record and sits first in the America East division.

Meditating “calms us and helps us visualize what we want to see in a game,” said India Pagan, a starter for Stony Brook and a graduate student with an extra year of eligibility because of the COVID pandemic.

A standout guard for Tulane University who finished her college career first in assists, Langford appreciates how hard the team has worked and how well they’ve come together.

“Our chemistry has been really good early on, to the point where, sometimes, [I wonder] is it November or is it March?” she said.

With five players averaging double digits in scoring, Stony Brook becomes harder to guard.

“On any given night, we’re moving and sharing the ball,” Langford said. “They are selfless. They don’t care who has the most points.”

While earning a spot in March Madness this year for just the second time in the program’s history would be rewarding, Langford focuses on each game.

“I’m a person that stays in the moment,” Langford said. “As long as we’re getting better, that puts us in a position to win the next game.

To that end, Langford would like the team to continue to improve in its transition defense.

She would like to see the team, which includes starters Earlette Scott, Gigi Gonzalez, Leighah-Amori Wool, Anastasia Warren and Pagan, continue to collect more offensive rebounds.

Langford’s assistant coaches, which includes recruiting coordinator Shireyll Moore, have been searching for players who might join the program as student-athletes.

“We’re in the position we are today because we have pretty good players,” Langford said. “My staff does a lot of this. They are more actively involved in the recruiting” each day.

Stony Brook has signed three current high school seniors and is focusing on juniors.

Before each game, Langford’s assistant coaches watch film of their opponents. They give her a cheat sheet before she watches film as well.

While Langford plans to stick to the team’s strengths, she will add a few wrinkles depending on the insights she gains about her opponents.

In the team’s first loss, Pagan and Warren were unavailable to play for medical reasons.

The team could have gone to Fordham feeling defeated, but the players fought to the end in a game they lost, 71-59.

“They don’t like losing, we don’t like losing,” Langford said. “They have responded well this week.”

The start of a season as head coach has taught Langford several lessons, including pacing herself and, in particular, protecting her voice. She drinks tea all day long and tells her staff to remind her not to yell in practice, because she shouts over the band at games.

In practice, Langford grabs a ball periodically to demonstrate what she’d like to see from her players.

As for her activity during the game, Langford sits only for about the first 30 seconds and then works the sidelines.

Pagan appreciates the work Langford puts in and the way her new coach has improved her game. While she used to get three or four rebounds a game, she’s often snagging 10 or more.

Pagan also sees herself hustling more, particularly after Langford created a drill where the players dive for loose balls.

“Before, I wouldn’t think of diving for a ball. Now, it’s ingrained into my head,” Pagan said. “The hustle doesn’t stop until the whistle blows. You play until you can’t play any more.”

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By Leah S. Dunaief

Leah Dunaief

Among the many preparations we made for our family Thanksgiving gathering this year, was carefully considering how to prevent any intrusion by COVID-19, a most unwelcome guest. The children and grandchildren were coming from six different states, so the potential exposure was widespread.

We agreed that everyone would have the appropriate vaccinations, two and a booster if possible. Each member also bought an Abbott BinaxNOW antigen self test result that they took before starting out on their trips. Everyone tested negative, so we were full steam ahead.

Thanksgiving Day was filled with hugs, laughter and love. We had not been all together in almost two years, and much conversation resulted, including how the youngest one had grown. After the traditional sumptuous dinner, we went around the table and spoke about what we were most grateful for in the past year. This is of special value to me, in addition to the lovely feelings of gratitude evoked, because it gives me a chance to catch up on their various activities.

The next day, Friday, we talked, walked, played games and ate some more. I almost didn’t register when one of my grandsons came to the dinner table a little late because he was feeling “achy.” But when he asked for an Advil the next morning, I got out the At-Home rapid test, and in 15 minutes we knew he was positive. Thinking it might be a false positive, we drove him to Stony Brook University Hospital, where he was given a PCR test, the gold standard, and in four hours we had the result.

Somehow, in spite of our careful efforts, the pathogen had found us. We then went to the next step and self-quarantined, but we are still trying to figure out where the hole in our defenses lies. As nearly as we can conclude, a negative test does not check for viruses in low numbers that are just beginning their infection in the nose, for example, and are still too few to register. With no symptoms, there is no way to detect their presence. It typically takes at least three days before the alarm goes off. So even weekly testing, which is so often done by institutions and employers, is not foolproof, especially if the patient is asymptomatic.

Fortunately, because my grandson was doubly vaccinated, the illness was of short duration, although he did lose his sense of taste and smell for a bit. The rest of the family members are fine. But what does that mean for all of us? The potential for infection is there, still with us despite how much we would like to leave it behind and despite all precautions. Gatherings of almost any size carry some risk, especially when we remove our masks to eat together, and we cannot be mindless of the threat.

There may be some good news, however. Omicron, the latest variant to be identified, seems to cause a milder version of the disease, at least so the early evidence indicates. And there are now two different pills that appear to hold back the most harmful effects of the virus if taken within five days of onset. One is from Merck and Ridgeback Biotherapeutics, called molnupiravir, that reduces the risk of hospitalization and death by 30%. It should be receiving FDA approval soon, even though it can cause serious side effects. The other is Paxlovid from Pfizer and so far appears to be 85% effective, perhaps to be authorized by year’s end. Made of a different formulation, it probably would not cause the same side effects as Merck’s but could cause others. Both pills could turn out to be a stop gap if the vaccines prove ineffective against new variants. And both may be more powerful if given together, as research against the virus that caused AIDS proved at that time. According to Dr. Fauci, the government’s top infectious disease expert, who oversaw combination therapy for HIV years ago, such a clinical trial could be quickly done.

From left, Daniele Rosado and Ullas Pedmale examine a sample of the model plant Arabidopsis. Photo courtesy of Ullas Pedmale

By Daniel Dunaief

Many plants are in an arms race akin to the developers of skyscrapers eager to get the most light for their prized penthouse apartments. Only, instead of trying to collect rent from well-heeled humans, these plants are trying to get the most sun, from which they create energy through photosynthesis.

Plants are so eager to get to the coveted sunlight that the part growing towards the light sends a distress signal to the roots when they are in the shade. While that might help an individual plant in the short term, it can create such shallow and ineffective roots that the plant becomes vulnerable to unfavorable weather. They also can’t get as many nutrients and water from the ground.

This is problematic for farmers, who want plants that grow in the sun, but that don’t sacrifice the development of their roots in the shade. Ullas Pedmale, Assistant Professor at Cold Spring Harbor Laboratory, is working to lend a hand.

Pedmale, who recently published research in the journal Plant Physiology, is studying the signals the shoots, or the parts of the plants either in the sunlight or the shade, send to the roots.

Pedmale and postdoctoral researcher Daniele Rosado, who is the first author on the recent paper, explored the genes that turned on in the roots of the model plant Arabidopsis and tomato plants when these plants were in the shade.

When plants are in the shade, they “prioritize shoot growth and try to outcompete the neighboring plants,” said Rosado. “That’s when root development is compromised.”

Among the genes that are active when plants are in the shade is a family of genes called WRKYs, which affect gene expression and cause stunted growth in the roots.

WRKY genes respond to stress. Keeping WRKY genes on all the time, even when a plant is in the sun, caused stunted growth of the roots. WRKY proteins turn on or off other genes.

This can be problematic for farmers, who tend to try to increase yield by putting more plants in an area. At that point, the plants shade each other, which is “bad for the root system. If we can find a way to get the roots to grow normally, we can potentially increase yield,” Rosado said.

This could also remove more carbon dioxide from the air and store it in the developing roots, helping to mitigate the effect of global warming. “Our study can give a roadmap on how to make longer, deeper roots,” Pedmale said.

At this point, researchers still don’t know how the plant transfers information about the amount of sunlight it receives in the green chloroplasts where photosynthesis occurs to the WRKY genes, which are in the nucleus.

Researchers have been studying the shade response in the shoots of plants for over five decades. They have not, however, focused as much attention on the effect of less sunlight on the roots.

“We want to tackle this problem,” Pedmale said.

WRKY genes are a generalized stress signal, which is not just involved when a plant isn’t getting enough light. They are also turned on during pathogen attacks, stress and amid developmental signals.

Indeed, plants in the shade that have turned on these signals are especially vulnerable to attacks. Caterpillars, for example, can eat most of a shaded plant because the plant is so focused on growing its shoot that its defenses are down.

When that same plant is in the sunlight, it is more effective at defending itself against caterpillars.

At this point, Pedmale doesn’t know whether these genes and signals occur across a broad species of plants beyond tomatoes and Arabidopsis. He and others are hoping to look for these genes in grasses and grains.

Pedmale is also searching for other signals between the shoot and the root. “Plants are masters of adaptation,” he said. “They might have redundant systems” that signal for roots to slow their growth while the shoots tap into the available energy to grow.

Plants may also have natural molecules that serve as brakes for the WRKY signal, preventing the shoot from taking all the available energy and rendering the plant structurally fragile.

A scientist at CSHL for five years, Pedmale came to the lab because of the talent of his colleagues, the reputation and opportunity at CSHL and the location.

Born and raised in Bangalore, India, Pedmale enjoys reading fiction and autobiographies and wood working when he’s not in the lab. He recently made a book shelf, which provides him with a chance to “switch off” from science, which, he said, is a 24-hour job. He has taken wood pieces from his workshop and brought them to PhD classes at CSHL, where he can show them plant biology and genetics at work.

Pedmale and his wife Priya Sridevi, who also works at CSHL, have a mini golden doodle named Henry.

A native of São Paulo, Brazil, Rosado is married to plant biologist Paula Elbl, who is the co-founder of a start up called GALY, which is trying to produce cotton in a lab instead of in a field.

Rosado is the first in her family to attend a public university. She has been working in Pedmale’s lab for two years and plans to continue her research on Long Island for at least another year.

Rosado knew Pedmale had worked as a post doctoral researcher in the lab of celebrated plant biologist Joanne Chory at the Salk Institute for Biological Studies. She met Pedmale at a plant conference, where she expressed an interest in his research.

Longer term, Rosado hopes her research has a broader impact.

“If I’m lucky, I’ll be able to see the fruits of my work being applied to make a difference and help feed people,” she said.

As for his work, Pedmale is eager to understand and use the signals from one part of a plant to another, given that the plant lacks a nervous system. “Once we can understand their language,” he said, “we can manipulate it to increase yield.”

File photo by Kyle Barr/2019

By Allan Varela

Welcome to Dickens in December! The 25th annual Charles Dickens Festival has been gently extended with activities on Saturday, Dec. 11 and 18. The Village will present two concerts per day, one in the Masonic Lodge and one in the Village Center’s Skip Jack room. The not-to-be-missed Festival of Trees will delight all those who visit the Village Center’s second floor and the streets will once again play host to a host of Dickens street characters.

Saturday the 11th features Dave K at the Masonic Lodge at 1 p.m. and Sweet Melody Music Studio with the Blue Music Company and Sterling Sax at the Village Center at 3 p.m. Saturday the 18th features the Dorian Consort string trio at the Masonic Lodge at 1 p.m. with Songs of the Season returning at 3 p.m. in the Village Center. The concerts are free and masking up is highly recommended.

Come on down to say ‘happy holidays’ to our beloved Chimney Sweeps and hear caroling groups perform throughout the Village. The restaurants have all prepared a holiday repast, while the stores are ready to fulfill those special holiday gift requests. So, come one, come all — a splendid time is in store for everyone.

Allan Varela serves as chair for the Greater Port Jefferson-Northern Brookhaven Arts Council which hosts the Port Jefferson Charles Dickens Festival.

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Which diet has better cardiovascular outcomes?

By David Dunaief, M.D.

Dr. David Dunaief

Despite the great strides we have made in the fight against heart disease, it is still the number one cause of death in the United States. Can we alter this course, or is it our destiny?

A study involving the Paleo-type diet and other ancient diets suggests that there is a significant genetic component to cardiovascular disease, while another study looking at the Mediterranean-type diet implies that we may be able to reduce our risk factors with lifestyle adjustments.

 Most of the risk factors for heart disease, such as high blood pressure, high cholesterol, sedentary lifestyle, diabetes, smoking and obesity are modifiable (1). Let’s look at the evidence.

Do our genes matter?

Researchers used computed tomography scans to look at 137 mummies from ancient times across the world, including Egypt, Peru, the Aleutian Islands and Southwestern America (2). The cultures were diverse, including hunter-gatherers (consumers of a Paleo-type diet), farmer-gatherers and solely farmers. Their diets were not vegetarian; they involved significant amounts of animal protein, such as fish and cattle.

Researchers found that one-third of these mummies had atherosclerosis (plaques in the arteries), which is a precursor to heart disease. The ratio should sound familiar. It seems to coordinate with modern times.

The authors concluded that atherosclerosis could be part of the aging process in humans. In other words, it may be a result of our genes. Being human, we all have a genetic propensity toward atherosclerosis and heart disease, some more than others, but many of us can reduce our risk factors significantly.

I am not saying that the Paleo-type diet specifically is not beneficial compared to the standard American diet. Rather, that this study does not support that. However, other studies demonstrate that we can reduce our chances of getting heart disease with lifestyle changes, potentially by following a plant-rich diet, such as a Mediterranean-type diet.

Can we improve our genetic response with diet?

The New England Journal of Medicine published a study about the Mediterranean-type diet and its potential impact on cardiovascular disease risk (3). Here, two variations on the Mediterranean-type diet were compared to a low-fat diet. People were randomly assigned to three different groups. The two Mediterranean-type diet groups both showed about a 30 percent reduction in the risk of cardiovascular disease, compared to the low-fat diet. Study end points included heart attacks, strokes and mortality. Interestingly, the risk profile improvement occurred even though there was no significant weight loss.

The Mediterranean-type diets both consisted of significant amounts of fruits, vegetables, nuts, beans, fish, olive oil and wine. I call them “Mediterranean diets with opulence” because both groups consuming this diet had either significant amounts of nuts or olive oil and/or wine. If the participants in the Mediterranean diet groups drank wine, they were encouraged to drink at least one glass a day.

The study included three groups: a Mediterranean diet supplemented with mixed nuts (almonds, hazelnuts or walnuts), a Mediterranean diet supplemented with extra virgin olive oil (at least four tablespoons a day), and a low-fat control diet. The patient population included over 7,000 participants in Spain at high risk for cardiovascular disease.

The strength of this study, beyond its high-risk population and its large size, was that it was a randomized clinical trial, the gold standard of trials. However, there was a significant flaw, and the results need to be tempered. The group assigned to the low-fat diet was not, in fact, able to maintain this diet throughout the study. Therefore, it really became a comparison between variations on the Mediterranean diet and a standard diet.

What do the leaders in the field of cardiovascular disease and integrative medicine think of the Mediterranean diet study? Interestingly there are two diametrically opposed opinions, split by field. You may be surprised by which group liked it and which did not. Cardiologists, including well-known physicians Henry Black, M.D., who specializes in high blood pressure, and Eric Topol, M.D., former chairman of cardiovascular medicine at Cleveland Clinic, hailed the study as a great achievement. This group of physicians emphasized that now there is a large, randomized trial measuring clinical outcomes, such as heart attacks, stroke and death. 

On the other hand, the integrative medicine physicians, Caldwell Esselstyn, M.D., and Dean Ornish, M.D., both of whom stress a plant-rich diet that may be significantly more nutrient dense than the Mediterranean diet in the study, expressed disappointment with the results. They feel that heart disease and its risk factors can be reversed, not just reduced. Both clinicians have published small, well-designed studies showing significant benefits from plant-based diets (4, 5). Ornish actually showed a reversal of atherosclerosis in one of his studies (6).

So, who is correct about the Mediterranean diet? Each opinion has its merits. The cardiologists’ enthusiasm is warranted, because a Mediterranean diet, even one of “opulence,” will appeal to more participants, who will then realize the benefits. However, those who follow a more focused diet, with greater amounts of nutrient-dense foods, will potentially see a reversal in heart disease, minimizing risk — and not just reducing it.

Ultimately, even with a genetic proclivity toward cardiovascular disease, we have confirmation that we can alter our cardiovascular destinies. The degree depends on the willingness of the participants.

References:

(1) www.uptodate.com. (2) BMJ 2013;346:f1591. (3) N Engl J Med 2018; 378:e34. (4) J Fam Pract. 1995;41(6):560-568. (5) Am J Cardiol. 2011;108:498-507. (6) JAMA. 1998 Dec 16;280(23):2001-2007.

Dr. David Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com.