Arts & Entertainment

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Glenn Close and Amy Adams star in film adaptation of best-selling memoir by J.D. Vance. Photo courtesy of Netflix

Reviewed by Jeffrey Sanzel

In 2016, J.D. Vance published Hillbilly Elegy: A Memoir of a Family and Culture in Crisis. In it Vance examined his family’s Appalachian roots and values and how they affected their lives in Middletown, Ohio. He highlighted the contrast of loyalty and love of country with a history of violence and abuse. The book was an immediate but controversial bestseller.

So overwhelming was the response to his view on what were perceived as myths about poverty, the book Appalachian Reckoning: A Region Responds to Hillbilly Elegy was brought out in 2019.  This collection of essays criticizes Vance’s opinions and generalizations. Over the years, Vance has become a vocal social conservative.

From left, Haley Bennett, Gabriel Basso and Amy Adams in a scene from the film. Photo courtesy of Netflix

Netflix now offers a film adaptation that basically eschews the more direct political elements of the autobiography and instead focuses on his struggle both as a teenager and a student at Yale. With an engaging if narrow screenplay by Vanessa Taylor and focused direction by Ron Howard, they have chosen to tell a personal story that will still raise many of the questions and complaints resulting from the book.

The film alternates between 1997 and 2011, with the teenage Vance struggling with his home situation and the older Vance working three jobs while attending Yale and attempting to land a summer internship with a law firm in Washington. What ensues over the next two hours is the unwinding of his childhood history along with his present struggles as Vance returns home to once again deal with his volatile mother. In some ways, the film is a blending of the traditional coming-of-age story with the well-trodden dysfunctional family saga.

The film’s strength lies in its performances. Gabriel Basso plays the older Vance with a mix of stoicism and vexation as he tries to navigate his familial responsibility while trying to go advanced his life and career. He believably conveys the battle between past and future. Owen Asztalos, as the younger Vance, is the right mix of hope and disappointment. Both actors appear to be playing the same person which does not always happen in film.

Haley Bennett, as Vance’s sister, shows her love and commitment that is overwhelmed by a sense of weariness. Freida Pinto is fine with the rather unexplored and undeveloped Usha, Vance’s Yale girlfriend (and later wife).

But the film belongs to two compelling performances. Amy Adams is raw and fearless as Vance’s drug-addicted, mercurial mother, a nurse with both substance abuse and mental issues. She alternates between expressions of unconditional love and brutal physical and emotional attacks. It is unlike anything Adams has done prior, with truly visceral pain and rage. (If it all seems a bit too much, that responsibility should be attributed to Taylor and Howard.)

Glenn Close is a gifted actor with technical skills rivaled by very few (Meryl Streep, being one of them). Her performances are usually complete but sometimes there is a sense of the mechanics behind them. In this case, she has completely subsumed herself in the role of Vance’s grandmother. She is unrecognizable as the calculating matriarch with an ugly history (that is only alluded to once) and a presence focused on her grandson’s survival and growth, most importantly through education. In this cold and disconnected woman, Close has found a strange warmth. In stillness and action, when she is on screen, the film is hers.

Many will take exception to Vance’s —and hence the film’s — point-of-view and its simplistic and dubious portrayal of the causes and results of poverty. This is a valid and legitimate concern. However, Hillbilly Elegy is worth watching for the performances of two great American actors.

Rated R, Hillbilly Elegy is currently streaming on Netflix.

Gurwin Jewish Nursing & Rehabilitation Center, 68 Hauppauge Road, Commack will host a holiday-themed Festival of Lights drive-thru light display on its campus on Monday, Dec. 14 and Tuesday, Dec. 15, from 5:30 to 8:30 p.m.

The display will feature thousands of blue, gold and white lights arranged in a variety of scenes and include inflatable menorahs, dreidels and other holiday fun. Guests will be able to tune their car radio to a special FM station (107.7 FM) for a musical accompaniment to the visual experience.

“The pandemic has taken a toll on everyone, and we wanted to provide some cheer and a thank you to the communities that have helped our residents and honored our healthcare heroes this year,” said Stuart B. Almer, President & CEO of Gurwin Healthcare System.

Guests are urged to brighten the season for nursing home residents by bringing donations of unwrapped gifts  including puzzle books and pens, fuzzy holiday socks and other personal gifts.

The event is made possible by the generosity of sponsors, including Ambulnz (Presenting Sponsor), Advantage Title Agency, Inc., Gensler Cona Elder Law, Huntington Hospital Northwell Health, Setton International Farms, Unidine, Austin Williams and Jackson Lewis, PC.

The display is free of charge and no reservations are needed. For more information call 631-715-2563. Posts on social media can use the hashtag #GurwinLights.

Stock photo
With vitamin D supplementation, more is not necessarily better.

By David Dunaief, M.D.

Dr. David Dunaief

Here in the Northeast, we are quickly approaching the point in the year when we have the least daylight hours. This is the point at which many reach for vitamin D, one of the most important supplements, to compensate for a lack of vitamin D from the sun. Let’s explore what we know about vitamin D supplementation.

There is no question that, if you have low levels of vitamin D, replacing it is important. Previous studies have shown that it may be effective in a wide swath of chronic diseases, both in prevention and as part of the treatment paradigm. However, many questions remain. As more data come in, their meaning for vitamin D becomes murkier. For instance, is the sun the best source of vitamin D?

At the 70th annual American Academy of Dermatology meeting in 2012, Dr. Richard Gallo, who was involved with the Institute of Medicine recommendations, spoke about how, in most geographic locations, sun exposure will not correct vitamin D deficiencies. Interestingly, he emphasized getting more vitamin D from nutrition. Dietary sources include cold-water fatty fish, such as salmon, sardines and tuna.

We know its importance for bone health, but as of yet, we only have encouraging — but not yet definitive — data for other diseases. These include cardiovascular and autoimmune diseases and cancer.

There is no consensus on the ideal blood level for vitamin D. For adults, the Institute of Medicine recommends between 20 ng/ml and 50 ng/ml, and The Endocrine Society recommends at least 30 ng/ml.

Cardiovascular mixed results

Several observational studies have shown benefits of vitamin D supplements with cardiovascular disease. For example, the Framingham Offspring Study showed that those patients with deficient levels were at increased risk of cardiovascular disease (1).

However, a small randomized controlled trial (RCT), the gold standard of studies, called the cardioprotective effects of vitamin D into question (2). This study of postmenopausal women, using biomarkers such as endothelial function, inflammation or vascular stiffness, showed no difference between vitamin D treatment and placebo. The authors concluded there is no reason to give vitamin D for prevention of cardiovascular disease.

The vitamin D dose given to the treatment group was 2,500 IUs. Thus, one couldn’t argue that this dose was too low. Some of the weaknesses of the study were a very short duration of four months, its size — 114 participants — and the fact that cardiovascular events or deaths were not used as study end points.

Most trials relating to vitamin D are observational, which provides associations, but not links. However, the VITAL study was a large, five-year RCT looking at the effects of vitamin D and omega-3s on cardiovascular disease and cancer (3). Study results were disappointing, finding that daily vitamin D3 supplementation at 2000 IUs did not reduce the incidence of cancers (prostate, breast or colorectal) or of major cardiovascular events.

Mortality decreased

In a meta-analysis of a group of eight studies, vitamin D with calcium reduced the mortality rate in the elderly, whereas vitamin D alone did not (5). The difference between the groups was statistically important, but clinically small: nine percent reduction with vitamin D plus calcium and seven percent with vitamin D alone.

One of the weaknesses of this analysis was that vitamin D in two of the studies was given in large amounts of 300,000 to 500,000 IUs once a year, rather than taken daily. This has different effects.

Weight benefit

There is good news, but not great news, on the weight front. It appears that vitamin D plays a role in reducing the amount of weight gain in women 65 years and older whose blood levels are more than 30 ng/ml, compared to those below this level, in the Study of Osteoporotic Fractures (4).

This association held true at baseline and after 4.5 years of observation. If the women dropped below 30 ng/ml in this time period, they were more likely to gain more weight, and they gained less if they kept levels above the target. There were 4,659 participants in the study. Unfortunately, vitamin D did not show statistical significance with weight loss.

USPSTF recommendations

The U.S. Preventive Services Task Force recommends against giving “healthy” postmenopausal women vitamin D, calcium or the combination of vitamin D 400 IUs plus calcium 1,000 mg to prevent fractures, and it found inadequate evidence of fracture prevention at higher levels (6). The supplement combination does not seem to reduce fractures, but does increase the risk of kidney stones. There is also not enough data to recommend for or against vitamin D with or without calcium for cancer prevention. But as I mentioned previously, the VITAL study did not show any benefit for cancer prevention.

When to supplement?

It is important to supplement to optimal levels, especially since most of us living in the Northeast have insufficient to deficient levels. While vitamin D may not be a cure-all, it may play an integral role with many disorders. But it is also important not to raise the levels too high. The range that I tell my patients is between 32 and 50 ng/ml, depending on their health circumstances.

References:

(1) Circulation. 2008 Jan 29;117(4):503-511. (2) PLoS One. 2012;7(5):e36617. (3) NEJM. 2018 published online Nov. 10, 2018. (4) J Women’s Health (Larchmt). 2012 Jun 25. (5) J Clin Endocrinol Metabol. online May 17, 2012. (6) JAMA. 2018;319(15):1592-1599.

Dr. David Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com.

Photo by Tom Caruso

AUTUMN FAWN

Tom Caruso snapped this photo of a young whitetail deer in a meadow at Caleb Smith State Park Preserve in his hometown of Smithtown on Dec. 6. He writes, ‘I followed a small herd of deer for a while and was amazed by how comfortable they were with my presence. I snapped this picture of the smallest deer as it took a break from grazing to check me out. It was a great experience getting so close to them.’

Send your Photo of the Week to leisure@tbrnewspapers.com

Dennis Plenker Photo by Bob Giglione, 2020/ CSHL

By Daniel Dunaief

If the job is too easy, Dennis Plenker isn’t interested.

He’s found the right place, as the research investigator in Cold Spring Harbor Laboratory Cancer Center Director Dave Tuveson’s lab is tackling pancreatic cancer, one of the more intractable forms of cancer.

Plenker joined Tuveson’s lab in 2017 and is the technical manager of a new organoid facility.

Organoids offer hope for a type of cancer that often carries a poor prognosis. Researchers can use them to find better and more effective treatments or to develop molecular signatures that can be used as a biomarker towards a specific treatment.

Scientists can take cells from an organoid, put them in miniature dishes and treat them with a range of drugs to see how they respond.

The drugs that work on the organoids offer potential promise for patients. When some of these treatments don’t work, doctors and researchers can continue to search for other medical solutions without running the risk of making patients ill from potentially unnecessary side effects.

“Challenges are important and there is a sweet spot to step out of my comfort zone,” Plenker explained in an email.

Dennis Plenker Photo by Bob Giglione, 2020/ CSHL

In an email, Tuveson described Plenker as a “pioneer” who “likes seemingly impossible challenges and we are all counting on him to make breakthroughs.”

Specifically, Tuveson would like Plenker to develop a one-week organoid test, where tissue is processed into organoids and tested in this time frame.

Organoids present a cutting edge way to take the modern approach to personalized medicine into the realm of cancer treatments designed to offer specific guidance to doctors and researchers about the likely effectiveness of remedies before patients try them.

Plenker and others in Tuveson’s lab have trained researchers from more than 50 institutions worldwide on how to produce and use organoids.

“It’s complicated compared to conventional tissue culture,” said Plenker, who indicated that considerably more experience, resource and time is involved in organoid work. “We put a lot of effort into training people.”

Tuveson explained that the current focus with organoids is on cancer, but that they may be useful for other conditions including neurological and infectious diseases.

The way organoids are created, scientists such as Plenker receive a biopsy or a surgical specimen. These researchers digest the cells with enzymes into singular cells or clumps of single cells and are embedded. Once inside the matrix, they form organoids.

When they “have enough cells, we can break these down and put them into multi-well plates,” Plenker explained. In these plates, the scientists test different concentrations and types of drugs for the same patient.

It’s a version of trial and error, deploying a range of potential medical solutions against cells to see what weakens or kills cells.

“If you do that exercise 100 times, you can see how many times compound A scores vs. C, E and F. You get a sense of what the options are versus what is not working,” Plenker said.

While scientists like Plenker and Tuveson use targeted drugs to weaken, cripple or kill cancer, they recognize that cancer cells themselves represent something of a molecular moving target.

“There is a very dynamic shift that can happen between these subtypes” of cancer, Plenker said. “That can happen during treatment. If you start with what’s considered a good prognosis, you can end up with a higher fraction of basal cancer cells” which are more problematic and have a worse prognosis. “We and others have shown that you have a mixture of cell types in your tumor all the time.”

Part of what Plenker hopes to discover as the director of the organoid center is the best combination of ingredients to foster the growth of these versatile and useful out-of-body cancer models.

The gel that helps the cells grow is something Plenker can buy that is an extracellular matrix rich matter that is of murine, or rodent, origin. He hopes to develop a better understanding of some of these proprietary products so he can modify protocols to boost the efficiency of the experiments.

Plenker is “trying to innovate the organoids, and so he may need to adjust conditions and that would include inventing his own recipes,” Tuveson explained.

The facility, which received support from the Lustgarten Foundation, will engage in future clinical trials.

The type of treatments for pancreatic cancer patients typically fall into two arenas. In the first, a patient who is doing well would get an aggressive dose of chemotherapy. In the second, a patient who is already sick would get a milder dose. Determining which regimen is based on the current diagnostic techniques.

Plenker and his wife Juliane Dassler-Plenker, who works as a post-doctoral fellow in the lab of Mikala Egeblad at Cold Spring Harbor Laboratory, live in Huntington. The pair met in Germany and moved to the United States together.

Plenker calls himself a “foodie” and appreciates the hard work that goes into creating specific dishes.

In his career, Plenker always “wanted to help people.” He has appreciated the latest technology and has disassembled and put back together devices to understand how they work.

Prior to the pandemic, Plenker had gone on short trips to Germany to visit with friends and relatives. He is grateful for that time, especially now that he is much more limited in where he can go. He appreciates his landlord and a second American family which helps the couple feel welcomed and grateful.

In 2017, Plenker recalls attending a talk Tuveson gave in Washington, D.C. in which he invited anyone in the audience who wanted to improve a test to come and talk to him after the presentation.

“I was the only one in that regard who talked to him” after that lecture, Plenker said.

By Julianne Mosher

It’s not located on Gumdrop Lane, but you can spot it on North Huron Street in Ronkonkoma.

On the right-hand side of the dead-end street is a real-life gingerbread house. Adorned with nearly a thousand decorations across its front lawn, it’s like a miniature Disney World hidden in a Suffolk County suburb.

But although the property is not huge, it has drawn thousands of people each year, said Peter Tomasello, owner of the home .

“This is more of an amusement park,” he said. “We’re probably one of the only fully interactive displays in North America — it’s very unique, especially to Long Island.”

Tomasello’s love for Christmas began when he was a child. His grandmother would bring him to different houses around Long Island to look and admire their decorations.

“I was just blown away,” he said. “And I kind of wanted to be that house.”

So, from then on, he’d use his birthday and Christmas money to raid the stores selling discounted holiday decorations instead of buying games and G.I. Joes. He would decorate his childhood home every year on Shelter Road in Ronkonkoma before establishing his own place on the other side of town.

“I started to accumulate anything that I could at that point,” he said. “And then obviously, when I started to work and things like that, all bets were off. Now that I have my own house, it’s pretty much just go-time.”

When he and his husband, Drew Jordan, purchased their home at 135 North Huron St., Tomasello said his one condition was that they’d buy a gingerbread house. Soon enough, he found this location, and with a little extra paint, it has maintained its name as the Ronkonkoma Gingerbread House ever since.

“I’ve just always loved Christmas,” he said. “I’ve always loved happiness, and I love making other people happy and just giving them a magical kind of experience.”

Before COVID-19, Tomasello said between 500 to 1,000 people would visit his house per night. However, due to new regulations, he’s monitoring how many people can come and go to appreciate the lights, music and dancing stations in a safe, socially-distanced, way.

He said that starting around July, people were messaging his home’s Facebook page asking him if the light shows were still on this year. Being a staple in the community and knowing that other holiday traditions were being cancelled, he knew they had to open it up.

With COVID, the couple implemented some new rules, like mask-wearing and a cap on the number of people on the property at one time. There is a hand sanitizing station (with peppermint-scented sanitizer) for people not wearing gloves or mittens, and some stations have been changed so there is less contact.

Compared to other heavily decorated homes, the Gingerbread House has a light show with 12 stations where, when a button is pressed, a show begins with animatronics of elves baking cupcakes, Santa Claus and his wife preparing gifts, and Nutcrackers — who crack jokes.

Penguins play ice hockey across from Comet, the talking reindeer who reminds those stopping by to maintain social distancing. Lucy, from the Peanuts gang, gives advice on one side of the lawn, while Elsa and Anna sing “Let it Go” for families and lights blink along with the music.

“Every item here has its own story,” explained Tomasello.

The Frozen scene is in memory of his close friend’s daughter, who passed away just before her third birthday, and who loved the movie. And that family is also the reason the couple accepts donations upon arrival, with funds going directly to the Nassau/Suffolk Autism Society of America (NSASA). The little girl’s brother is autistic.

“It was really devastating for us because he didn’t even understand what was going on when his sister passed,” he said. “So that’s why we do the donation box for the Autism Society.”

While every year the front lawn looks different with new or returning scenes, the Frozen stage always comes back to remember her.

“We’re always going to have it,” he said. “That’s the heart of this place — being able to have the Frozen scenes.”

While they don’t charge for entry, the donations to NSASA are their way to give back.

“This is simply our philanthropy,” said Tomasello. “This is our way of giving back to the community in general, and obviously making whatever donations people want to bring to go to a good cause.”

He said that while seeing the smiling faces of the kids is great, he loves seeing the reactions of the parents and grandparents.

“You’re always going to please the kids, they’re always going to love it. But when you can make a 70-year-old feel like they’re seven, that’s cool … that’s really cool.”

The Gingerbread House, 135 N. Huron St., Ronkonkoma will be open daily through Jan. 1. Hours are Sunday through Thursday from 5:30 p.m. to 10 p.m., and Friday and Saturday from 5:30 p.m. to 11 p.m.

All photos by Julianne Mosher

Cookie

MEET COOKIE!

This week’s shelter pet is Cookie, a loving and happy 9-year-old pit bull mix. She adores every human she meets, can play for hours and gives the BEST snuggles.

Cookie

Cookie is very healthy and athletic. She needs a big yard where she can play fetch with her family. Sadly she has been in the shelter for over a year and doesn’t understand why she is overlooked time and time again. Do not be fooled by her age — Cookie has a young heart, mind and body and lives to please everyone she meets. She would be good with kids 8 and up, but must be the only pet in the home. She comes spayed, microchipped and is up to date on her vaccines.

If you are interested in meeting Cookie, please call ahead to schedule an hour to properly interact with her in the shelter’s Meet and Greet Room.

The Smithtown Animal & Adoption Shelter is located at 410 Middle Country Road, Smithtown. Shelter operating hours are 8 a.m. to 5 p.m. during the week, 8 a.m. to 4:30 p.m. on the weekend. For more information, please call 631-360-7575 or visit www.smithtownanimalshelter.com.

METRO photo

By Linda Toga, Esq.

Linda Toga, Esq.

THE FACTS:

My aunt Mary died recently. She was widowed and had no children. My father, her only sibling, died a few years ago. In her will Mary named me as the executrix of her estate and the sole beneficiary. The attorney who drafted the will expected to be retained to handle Mary’s estate but I have worked with a different attorney and want to work with him in connection with the probate of Mary’s estate. The drafting attorney has the original will and has refused to give it to me.

THE QUESTIONS:

Must I retain the drafting attorney to handle the probate of my aunt’s will? If not, must he turn the will over to me or my attorney?

THE ANSWER:

The short answer to your first question is an emphatic “NO”! Although many attorneys assume and likely hope that the families of their estate planning clients will retain them to handle the estates of those clients when they die, there is absolutely no legal basis for the drafting attorney to insist that he/she be retained by the named executor to assist with the probate of the estate. If your aunt wanted the drafting attorney to handle her estate, she certainly could have named him as executor. Since she named you, you are free to retain any attorney you want to assist you with the probate process.

As for whether the drafting attorney must provide you or your attorney with the original will, it would clearly be better if the drafting attorney simply agreed to turn the will over to you or your attorney. However, if that does happen, all is not lost since New York law provides a mechanism for compelling a person who is holding an original will of a decedent to file that will with the surrogate’s court.

If polite requests for the will are ignored, your attorney can commence a proceeding in the surrogate’s court to compel the drafting attorney to produce the will. If the court determines that the drafting attorney did not have good cause to withhold the will, the court may not only order the attorney to file the original will with the court but, can also order the drafting attorney to reimburse you for the attorney’s fees you paid in connection with the proceeding.

Obviously, unless there is a good reason why the drafting attorney will not provide you or your attorney with the will, it is in his/her best interest to simply turn it over without the need for court intervention.

Linda M. Toga, Esq provides legal services in the areas of estate planning and administration, real estate, small business services and litigation. She is available for email and phone consultations. Call 631-444-5605 or email Ms. Toga at [email protected].

THE SECOND SPIRIT Andrew Lenahan stars as the Ghost of Christmas Present in Theatre Three’s virtual production of ‘A Carol for Christmas.’ The show premieres on Dec. 12. Photo by Eric J. Hughes

Theatre Three in Port Jefferson will premiere A Carol for This Christmas, a virtual performance adapted from Charles Dickens’ A Christmas Carol, on Dec. 12.

For over thirty-five years, Theatre Three has been presenting its acclaimed production of A Christmas Carol to thousands of Long Island theatergoers.  To continue this tradition, the theater has produced a virtual production that will be accessible through the theatre’s website and Facebook page on the Vimeo platform.

This new take on the holiday classic features six actors playing the many roles in the holiday classic, filmed socially distanced, with actors both onstage and in the theatre’s auditorium.  Jeffrey Sanzel has played Scrooge nearly 1,500 times and will once again play the miser who is redeemed by the ghosts of Christmases Past, Present, and Future.  He is joined by Theatre Three Christmas Carol veterans Andrew Lenahan, Michelle LaBozzetta, Linda May, Douglas J. Quattrock, and Steven Uihlein.

Sanzel has adapted and directed the 40-minute presentation, adhering closely to the heart and spirit of the 177 year-old novel.  Melissa Troxler is the Director of Photography.

As a gift to the Long Island community, the presentation will be offered for free at www.theatrethree.com. Donations to Theatre Three are greatly appreciated.

A Carol for This Christmas is made possible by the sponsorship of Andrew Markowitz.