Authors Posts by Daniel Dunaief

Daniel Dunaief

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As children return to school this fall, doctors in Suffolk County expect COVID-19 cases to rise. Photo by Ronny Sefria from Pixabay

People may think COVID-19 is out of sight and out of mind, but the virus, which is still around and is making people sick, doesn’t care. 

The new variant of COVID, EG.5, or “Eris,” is making people sick in the area, with hospital admissions and visits creeping up over the last few weeks.

Left, Dr. Gregson Pigott, commissioner of the Suffolk County Department of Health Services. Right, Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital. Left file photo; right file photo from Stony Brook Medicine

As of Aug. 9, 105 patients were hospitalized with COVID across the entire Northwell system, including 82 people on Long Island. That compares with 63 hospitalized patients on July 9, with 46 on Long Island exactly a month earlier.

That’s also the case for other area hospitals, doctors said.

“The numbers are definitely going up,” said Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital. “That’s probably a snapshot of what we expect in the fall and the winter.”

Dr. Gregson Pigott, commissioner of the Suffolk County Department of Health Services, explained that COVID-19 is “no longer an emergency” but is “still with us and we continue to see new variants.”

In an email, Pigott explained that the county has seen a “slight uptick in hospitalizations” that is still low in comparison to the earlier days of the pandemic.

He urged those at high risk to take precautions that could include avoiding crowded places, wearing a mask and meeting people at outdoor venues rather than indoors.

While the numbers of people sick with COVID are substantially lower than they were during the worst of the pandemic in 2020, health care professionals suggested that the fall and winter could be challenging for families, particularly as children return to school.

“The first two weeks of school, every kid is sick,” said Nachman. “Come November-ish, that’s when we see” that increase.

Dr. Bruce Hirsch, attending physician in Infectious Disease at Northwell Health, also anticipates a rise in COVID-19 cases coming this fall and early winter.

“I think there’s a very good chance that a lot of people will be having COVID,” he said.

Hirsch added that the symptoms for those people who don’t have underlying medical conditions, such as cardiac or lung-related problems, are likely to be considerably milder than they had been in the early stages of the disease, when no one had resistance.

“The sickness will not have the severity and mortality except in those of us who are unfortunate to have weak immune systems, other health problems or who are elderly or frail,” Hirsch said.

Pigott added that Eris, which is a subvariant of omicron, is not a variant of interest or concern, according to the World Health Organization.

Vaccine options

Doctors urged people to consider getting vaccines for COVID, the flu and respiratory syncytial virus for this coming fall.

The Centers for Disease Control and Prevention and the U.S. Food and Drug Administration are expected to approve the latest booster for COVID in late September or early October.

The newest booster, which should be available from Pfizer, Novavax and Moderna, should include protection against the latest COVID strain.

“The new booster formulation is much more similar and much more protective [against] the current strains,” Hirsch said. “The booster available now is protective against a couple of strains ago.”

Pigott urged people to get the new vaccines in the fall when they become available and before the holidays.

The vaccination may not prevent infection or all symptoms, but doctors suggested it would make illnesses shorter and less severe and could make the virus less infectious.

That could be particularly helpful for those who might otherwise develop more significant symptoms as their bodies attempt to fight off the virus.

Health care professionals suggested residents could receive several vaccines at the same time, enabling their immune systems to build resistance to a host of potential health threats.

“Our immune systems can chew gum and walk at the same time,” said Hirsch. “They are miraculous at reacting to all kinds of things every day anyway. The immune system is more than up to the challenge of handling two [shots] at the same time.”

Receiving several shots at once could give people a sore arm and a short-term fever that will likely respond to Tylenol, Nachman said.

“The science has shown that if you give a bunch of vaccines, you get a great response to everything,” Nachman added.

People who would prefer to get the vaccines in separate doses should space them out over several weeks, rather than getting one after another on consecutive days, she said.

Warning to pregnant women

Apart from viral infections, doctors warned pregnant women and those who might get pregnant  this winter about the ongoing shortage of a form of penicillin to treat syphilis.

Penicillin G benzathine, or Bicillin, is expected to be in short supply through the start of the summer of 2024.

The medicine is not only the only treatment recommended for pregnant people with syphilis, but is also the only one recommended for infants.

“We are prioritizing that medicine specifically only for that vulnerable population,” said Nachman.

The dangers of syphilis in pregnant women are significant, with the CDC estimating that about 40% of babies born to women with untreated syphilis can be stillborn or die from the infection.

Other dangers from syphilis include bone damage, anemia, enlarged liver and spleen, jaundice, nerve problems causing blindness or deafness, meningitis and skin rashes.

With cases of congenital syphilis more than tripling in recent years, the demand for Bicillin has exceeded the supply.

“It has been a concern for those in our Bureau of Sexually Transmitted Diseases,” Pigott explained. “They have been in consultation with the state. We defer to the state regarding supply.”

Locally, hospitals have been exploring other options without much success.

“We are looking for alternatives” to Bicillin, said Nachman, but “we are not necessarily finding them.”

Doctors urged pregnant women who think they might have syphilis to get tested to protect themselves and their unborn children.

By Daniel Dunaief

A problematic atmospheric greenhouse gases, methane comes from natural gas, agriculture, and swamps. 

John Mak

Recently, John E. Mak, a Professor in the School of Marine and Atmospheric Sciences at Stony Brook University worked with an international group of scientists to demonstrate a process that removes methane from the atmosphere.

A mixture of dust from the Sahara and sea spray reacts with methane to form carbon monoxide and a small amount of hydrochloric acid.

In a recent paper published in the prestigious journal Proceedings of the National Academy of Sciences, Mak, corresponding author Matthew Johnson, who is a Professor in the Department of Chemistry at the University of Copenhagen, and others showed how a novel process removes 5 percent, plus or minus 2 or 3 percent, of the methane from the atmosphere in specific areas.

“What we are showing is that some methane in the middle of the tropical Atlantic Ocean region may be removed” through this process, Mak said from the Gordon Research Conference on Atmospheric Chemistry in Sunday River, Maine.

The research validates a mechanism Mak had proposed in the late 1990’s, when he conducted studies funded by the National Science Foundation in Barbados. “When I first made the observations, I proposed that what we were seeing was a chlorine mediated removal of methane,” Mak explained.

At that time, he didn’t have the ability to make those measurements. The technology, however, has evolved over the years and researchers can now measure chlorine radical precursors such as Cl2 and other chlorine compounds.

Indeed, Maarten van Herpen, first author on the study and a member of Acacia Impact Innovation, approached Mak with a new theory and a new mechanism that he thought could explain Mak’s results from decades earlier.

“They were excited to hear that no one had solved the problem,” said Mak.

By working together through this international team, the group was able to take new measurements and utilize advances in their understanding of atmospheric processes.

‘New, but old’

Mak had conducted his studies towards the beginning of his time at Stony Brook University in the late 1990’s as a part of one of his first federally funded projects. 

“It’s a little unusual for people to make use of observations so far in the past,” said Mak. “It opens up a new, but old avenue of research.”

Mak, who is conducting studies in other areas including a recent project in New York to investigate air quality and air chemistry mechanisms specific to the greater New York City region, believes the research on this PNAS paper takes him almost full circle back to this earlier work.

“There’s a feeling of satisfaction that good measurements are useful for a longer period of time,” he said. 

In this study, Mak helped interpret some of the data his collaborators generated.

The reactions

The process of removing methane starts with sea spray, which is aerosolized by bubbles bursting at the contact point between the ocean and the air. The chlorine comes from that sea spray, while iron comes from the continental crust.

Saharan dust can traverse the globe, but scientists are not sure of the spatial extent of this process. They believe it could be throughout the tropical Atlantic, but it could be in other dust laden ocean regions in the Indian and Pacific Oceans as well.

That process creates what is described as a reactive chlorine species, which is on the hunt for a positively charged particle, such as one of the four hydrogen atoms attached to carbon in methane.

Once the chlorine removes a hydrogen, it creates a methyl group, or CH3, and an incredibly small amount of hydrochloric acid, or HCl, at about one part per quadrillion.

The acid, in fact, is so low that it doesn’t cause any acidification of the oceans. Ocean acidification primarily comes from the absorption of carbon dioxide gas, which reacts with seawater and eventually increases the amount of positively charged hydrogen atoms, decreasing the ocean’s pH.

Meanwhile in the atmosphere, the remaining methyl group is oxidized to carbon monoxide, which eventually becomes carbon dioxide. That is also a greenhouse gas, but is not as potent at trapping heat in the atmosphere as methane.

Now that the group has explored this process, Mak explained that the next step will involve proposing a field campaign in the tropical Atlantic with state of the art instruments.

Mak believes the journal PNAS likely found the subject matter compelling on a broader scale, particularly because this process affects weather and climate.

Outside work

When he’s not working, Mak enjoys boating and fishing. A native of Southern California, Mak is a commercial pilot, who also does some flying as a part of his research studies.

As for climate change, Mak suggested that the weather extremes from this year, which include record high temperatures in the ocean near the Florida Keys and high temperatures in areas in Arizona, are a part of a pattern that will continue.

“What we have been and will continue to observe are changes to the broad equilibrium of energy balance of the Earth ocean atmosphere system,” he explained. “There’s a lot of inertia in the system. But when you change the input by changing the forcing, you upset that equilibrium.” That, he explained, could alter the weather, which is generated as a response to differences in energy from one place to another.

The Pediatric Infectious Diseases Group at Stony Brook Medicine’s new regional tick-borne disease center, located in the Hampton Bays Atrium. From left, Dr. Andrew Handel, Dr. Dalia Eid, Dr. Christy Beneri and Dr. Sharon Nachman. Photo from Stony Brook Medicine

Stony Brook University is planning to open the first and only dedicated tick clinic in the northeast on Monday.

Supported by doctors from Stony Brook Medicine’s Meeting House Lane Medical Practice and Stony Brook Children’s Hospital, the new regional tick-borne disease center, which is located in the Hampton Bays Atrium, will provide by-appointment treatment for children and adults for tick bites and diagnose tick-borne illnesses.

The timing could be especially important for people with tick bites, as the previous warm winter allowed more ticks and their eggs to survive.

“They are out there, happily laying eggs and the eggs will hatch,” said Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital.

Brian Kelly of East End Tick and Mosquito Control donated the center’s suite which includes a reception area, two exam rooms, two private offices for consults and a nurse’s station, for 10 years.

“Between the beautiful weather in the winter and the nice weather in the summer, ticks are outside,” Nachman said. “I’m thrilled we’re doing it now. There’s no time like the present to move forward and work with the community to get this done.”

Tick checks

Health care providers urged parents, caregivers and anyone who spends quality time in nature to do regular tick checks.

Ticks can be so small that they look like a little freckle. These ticks can harbor diseases beyond the dreaded and oft-discussed Lyme Disease. Other diseases include babesiosis, ehrlichiosis and anaplasmosis.

In general, Nachman urged patients not to send ticks they pulled off themselves into the center.

“It’s the tick that they didn’t see that’s also putting them at risk,” she said. The clinic will determine the type of tests to run based on the symptoms.

For tick bites, as with many other health challenges, time is of the essence.

A tick that’s attached itself to a human for fewer than 48 hours likely won’t lead to an infection. Someone with a tick bite for about 48 hours might get a single dose of an antibiotic. People who had a tick bite for over that period might develop a rash or even facial palsy, in which one side of the face droops for an extended period of time.

Doctors work with patients to try to hone in on the date of a possible tick bite.

“We do pretty good guessing,” said Nachman. “We don’t need to be perfect: we need to be pretty close.”

Ticks are present throughout Suffolk County.

Health care workers urge people to spray their clothing with DEET. While ticks aren’t always easy to see, people can find them by feeling a new lump or bump on their skin.

Removing ticks

Nachman advised people to wipe an area with a tick down with alcohol before trying to remove an embedded insect.

Using a flat edged tweezer, the tick removers should grasp the insect and slowly back it out.

“Don’t grab the tick and yank,” Nachman cautioned. The mouth parts of the tick have an adhesive, which can leave some of the parts inside the infected person.

Nachman, who will be at the center on Mondays, also urged people not to use petroleum jelly or match sticks.

The hours at the center will adjust to the demand. In the winter, when ticks are less prevalent, the center may have more limited appointment times.

One of the advantages of the center is that the health care providers can track patients over time who have been infected.

Doctors can also sign patients up to become a part of a registry. By tracking people who have tick-borne infections, doctors might also address questions that are part of the science of diseases like Lyme.

“There may be better treatments or better tests” down the road, Nachman added.

A scene from 'Oppenheimer'

By Daniel Dunaief

Daniel Dunaief

My wife and I are wildly out of practice at an activity we used to do on dates.

Hey, I’m talking about going to movies. What did you think I meant? Never mind.

Anyway, after three and a half years, we finally ventured out to see a movie. No streaming at home, not taking a long walk through the neighborhood to see all the usual other walkers, and no hanging out in the backyard to look up at stars whose light was sent to us years ago.

I don’t think the light we can see was sent to us when dinosaurs were roaming the Earth.

We had purchased tickets online, with the customary and annoying convenience fee surcharge for something that couldn’t possibly be easier for the movie theater, and were excited to see a movie on the big screen.

Previews have always appealed to us, as has the satisfaction of seeing the entire movie from the start. When both of us were young, we found ourselves in movie theaters after the film began.

We’d sit in our seats and wait for the next showing, when we’d catch up to the point when we entered and, often with our respective families, head to the exits to piece together the narrative.

On a recent Sunday night, we drove through a packed parking lot. Clearly, the Barbenheimer phenomenon – the combination of hits “Barbie” and “Oppenheimer” – has brought the crowds back to the theaters that somehow survived the pandemic.

With almost no line, we breezed through the entrance and got on the short line for popcorn. Ah, movie popcorn. Yes, it’s much more expensive than it needs to be, and yet, we splurged for it many times as we prepared to suspend disbelief and enter the altered and captivating reality of a movie.

The concession didn’t sell bottled water, which we could fill with any beverage of our choice. We reluctantly agreed to buy the expensive cup and added ice cold water to our movie-time meal.

The days of waiting in line for the free-for-all of finding the best middle seats are long gone. We walked up to our wide, comfortable seats. When we didn’t immediately find the recliner button, the woman to my wife’s right showed us where it was.

Back in the early days of our children’s lives, when we were incredibly sleep deprived, those seats would have been a welcome opportunity for a solid nap.

Not this time. We were locked in and ready for the film. As is our wont, we quickly finished the first bucket of popcorn before the previews. I raced back for a refill and returned just in time for the start of several coming attractions.

Most of those previews looked somewhere between awful and horrific. If those were the best scenes from coming films, it may be a while before we feel the urge to return to the world of overpriced popcorn and comfortable chairs.

So, after all this time, are you wondering what we saw?

Well, we got sucked into the Barbenheimer vortex, opting for the World War II film instead of the late 50’s iconic toy.

With gripping subject matter and extraordinary acting from a cast ready to personify critically important figures from a turbulent time in 20th century history, the movie was compelling.

I can see why it received rave reviews. As a film watcher – okay, well, as a former passionate devotee of the silver screen – I wasn’t completely moved by the broad story telling.

As a science writer, which is the other hat I wear with privilege regularly for these papers, I was hoping there had been a greater description about the discoveries Oppenheimer and his collaborators had to make to complete the Manhattan Project.

At one point during the movie, I realized that we were watching the film on the 78th anniversary of the bombing of Hiroshima. The eery overlap brought home the complicated legacy of a talented scientist and effective leader.

JoAnne Hewett leads her first staff meeting as the new lab director at Brookhaven National Laboratory Tuesday, Aug. 8. Photo from BNL

In her first week on the job, JoAnne Hewett has been taking walks around campus — and she likes what she sees.

The first woman to lead the 76-year old Brookhaven National Laboratory, Hewett has explored a facility primarily funded by the Department of Energy that conducts groundbreaking research in Energy & Photon Sciences, Environment, Biology, Nuclear Science & Nonproliferation, Computational Sciences, Nuclear & Particle Physics and Advanced Technology Research.

The walks Hewett has taken have been “my way of learning where all the buildings are,” said Hewett in an exclusive interview with TBR News Media. “I truly love stumbling across things I didn’t know BNL had.”

One night, Hewett walked to an enormous greenhouse, which, as a gardener who enjoys growing tomatoes, chili peppers and citrus, intrigued her.

In meeting people at these facilities, Hewett has been “impressed” at “how dedicated they are to the mission and to the science that can be done here.”

Most recently the associate lab director for fundamental physics and chief research officer at SLAC National Accelerator Laboratory, Hewett brings extensive experience in theoretical physics to BNL and Stony Brook University, where she serves as Professor in the Department of Physics and Astronomy and Professor at the C.N. Yang Institute for Theoretical Physics.

Throughout her career, Hewett has been the first woman to serve in a host of roles. That includes as the first woman faculty member at SLAC in 1994, the first woman associate lab director and the first woman chief research officer.

“The best way to serve as a role model is to just do a good job at whatever it is you’re doing,” Hewett said.

In her many roles, Hewett has received numerous emails from students eager to meet her.

“Don’t get discouraged,” she tells them. “You’re going to get more roadblocks than others, potentially [but] hopefully not. Don’t get discouraged. Just keep working. If you love science and want to do science, if it’s the passion in your belly, just do it.”

Hewett has been successful in her career in part because she describes herself as “stubborn by nature.”

Cultural priorities

In her tenure as lab director for a facility with over 2,760 staff members, Hewett plans to emphasize the importance of creating a respectful work environment.

“It should be number one for everybody, everywhere to foster a respectful workplace environment, so that each person that comes into work in the morning or whenever they start their shift can do the very best that they can,” she said.

Additionally, she will stress the importance of safety at the Upton-based lab, where seven projects have led to Nobel Prizes.

“A good safety culture also promotes a good workplace environment,” said Hewett. “If you don’t do your work safely, you can’t do your work.”

Science vs. management

While research and management require the use of different parts of the brain, Hewett suggested her professional and administrative goals have overlapping approaches.

“In both cases, you need to be very strategic about your thinking,” she said. “When you’re doing research, you need to think about the best way to spend your time.”

She had a “ton” of ideas in theoretical physics and needed to be strategic about how she spent her time. As a manager, she also needs to be strategic about the programs she supports to ensure they are advancing.

In addition to creating a respectful and safe workplace, Hewett would like to delve into the beautification of the campus.

“I want to involve the staff” in that effort, she said.

Hewett served as a mentor from 2008 to 2011 for Rouven Essig when he was a postdoctoral researcher at SLAC.

In an email, Essig, who is now Professor of Physics at the C.N. Yang Institute for Theoretical Physics, described her as “an exceptional leader” who is “friendly and approachable” with a “clear vision.”

Essig lauded Hewett’s vision for recognizing the value of funding small-scale experiments in particle physics, which are low-cost but can enable “major discoveries,” he added. “I think this approach is having a big impact in particle physics research in the U.S. and elsewhere.”

Essig is “excited to see how she will further strengthen BNL and the connections to Stony Brook.”

Hewett has had “numerous important contributions to our understanding of physics beyond the Standard Model and how it can be discovered with experiments,” Essig added.

In her career, Hewett found it “terrifically exciting to discover something” in which she was the “only person in the world for that instant of time that knows something,” she said.

For her, that moment occurred when she was developing work on a particular theory of extra spacetime dimensions.

Collider appeal

Hewett came to BNL in part because of the ongoing construction of the Electron Ion Collider, which will study quarks and gluons in the nucleus and the strongest forces in nature.

“I did a lot of studies of potential future colliders,” said Hewett. “I’m excited to be at a lab where a collider will be built.”

Dr. Anthony Szema, director of the International Center of Excellence in Deployment Health and Medical Geosciences, Northwell Health Foundation. Photo courtesy Northwell Health

Wednesday, Aug. 9, is an important deadline for veterans who were exposed to burn pits.

That is the cutoff point when veterans can file claims for health issues that date back to the passage of the PACT Act in August 2022. If they file paperwork by Wednesday, they can get retroactive benefits.

“It’s very important” that veterans who might have health-related problems file for these benefits before that deadline, said Dr. Anthony Szema, director of the International Center of Excellence in Deployment Health and Medical Geosciences, Northwell Health Foundation. 

A veteran filing after Aug. 9 may only qualify for prospective medical care.

“The sooner you apply, the more benefits you may be eligible for,” explained Fernando X. Burgos Ortiz, Public Affairs Officer at the Northport VA Medical Center.
If veterans apply for PACT-related benefits on or before August 9, their benefits may be backdated to August 10, 2022.

People who are not ready to submit a full claim by then can also submit a quick “intent to file” and still receive the effective date, explained Burgos Ortiz. Veterans and survivors can visit va.gov/PACT to apply or submit their intent to file through the link: Your intent to file a VA claim | Veterans Affairs.

Veterans who apply after Aug. 10 may still be eligible to have their benefits backdated by one year, if they would have been eligible for PACT benefits on Aug. 10, 2022. A veteran who applied in December 2025 could have their benefits, if granted, backdated to December 2024. In that case, however, they would miss out on the earliest possible effective date of Aug. 10, 2022, which would mean they would miss out on a couple of years of benefits, Burgos Ortiz wrote.

‘You got exposed to a ticking time bomb, and we need to defuse it now so it never becomes a problem.’ — Dr. Anthony Szema

With support from numerous veteran advocates, including comedian John Stewart, Burn Pits 360 and others, Congress passed the PACT Act last August to ensure that veterans exposed to toxins from particles aerosolized by burn pits received ongoing medical support.

Szema, who specializes in asthma and lung fibrosis, urged all veterans who might qualify for these benefits to call their local VA and ask how to file for PACT Act benefits.

Through its offices on 3771 Nesconset Highway in Suite 105 in South Setauket, Northwell Health provides special testing to confirm the potential health effects of this exposure.

Last week, two veterans had such evaluations, while three signed up for Tuesday.

Conditions covered on the list include a wide range of health issues, including brain cancer, any type of gastrointestinal cancer, glioblastoma, head cancer, kidney cancer, lymphoma of any type, melanoma, neck cancer of any type, pancreatic cancer, reproductive cancer and respiratory cancer.

Covered conditions also include asthma, chronic bronchitis, COPD, emphysema, granulomatous disease, interstitial lung disease, pleuritis, pulmonary fibrosis and sarcoidosis.

Around the country, 2.5 million vets could receive benefits, including 8,000 in the greater New York Metropolitan area, Szema said.

“Thousands of vets are unaware” of the deadline, he added.

Prior to the PACT Act, Szema said the VA denied about 80% of claims. Now, presumptive conditions are covered rather than on a case-by-case basis.

Szema suggested that many veterans who breathed the air around burn pits and were living in dusty environments in Iraq and Afghanistan could be asymptomatic today, but might already be headed toward future health crises.

“If you believe [people who lived near the] World Trade Center have disease, this is worse, because you live 300 yards away from trash being burned with jet fuel in open air,” he said.

Szema said the tests Northwell conducts provide a more accurate reading of potential breathing or allergic problems in a shorter time. Northwell uses pulmoscan impulse oscillometry, in addition to respiratory muscle strength and multi test percutaneous allergy testing with plastic, which doesn’t involve needles.

Northwell has 10 remote patient monitoring systems from Bodimetrics that allows them to monitor continuous oxygen saturation and heart rate variability of veterans. The information also goes to the smart phones of veterans and to a remote modeling team with a nurse and to a cardio thoracic surgeon in Kansas.

Northwell is in discussions to obtain more of these systems.

Szema recently published a paper indicating that 29% of veterans exposed to burn pits reported seeing blood in their urine. Exposure to benzene and naphthalene in JP-8 jet fuel poses a risk of bladder cancer.

“It is never normal to have blood in the urine, even if it is kidney stones,” Szema wrote in an email. “Since these veterans were exposed to carcinogens, a thorough evaluation is paramount.”

Szema added that soldiers who answered the call of duty may not have symptoms but could develop them in the coming years.

“You got exposed to a ticking time bomb, and we need to defuse it now so it never becomes a problem,” he said.

Developing awareness

Szema was chief of the allergy section of Veterans Affairs Medical Center at Northport between 1998 and 2015. Between 1998 and 2004, his patients were primarily 80-year old Caucasian men who were in wheelchairs and needed oxygen.

All of a sudden, in September 2004, he and a medical student and “everybody was 20 years old in uniform” with patients who were brown, African American, black, hispanic, Southeastern Asian and Native American, reflecting the “entire diversity of Long Island.”

An index case of an all-state football player raised his level of concern, as the athlete didn’t smoke, vape or smoke marijuana but had shortness of breath. 

At first, Szema thought his physical problems came from inhaling dust from storms. That prompted him to initiate his first study reporting asthma among veterans returning from deployment to Iraq and Afghanistan near burn pits.

Szema testified before the United States Senate Policy Committee in Washington, D.C. in 2009.

He urged veterans who think they might qualify for these benefits to reach out to Three Village Asthma in South Setauket at 631-675-6474. The office is across the street from Jefferson Ferry.

“Now is the time,” Szema said. “At least if you get diagnosed with a condition related to your exposure, you can receive timely treatment.”

Maurizio Del Poeta. File photo from SBU

By Daniel Dunaief

Maurizio Del Poeta is taking another approach to battling fungal infections that can be deadly, particularly for people who are immunocompromised.

Maurizio Del Poeta. Photo from SBU

A Distinguished Professor at Stony Brook University in the Department of Microbiology and Immunology at the Renaissance School of Medicine at Stony Brook University, Del Poeta has made progress in animal models of various fungal infections in working on treatments and vaccines.

After receiving an additional $3.8 million from the National Institutes of Health for five years, Del Poeta is expanding on some findings that may lead to a greater understanding of the mechanism that makes some fungal infections problematic.

The Stony Brook Distinguished Professor is studying “what makes people susceptible to fungal infections,” he said. “It’s something I’m really passionate about.”

Del Poeta explained that researchers and medical professionals often focus on the people who get sick. Understanding those people who are not developing an infection or battling against a fungus can provide insights into ways to understand what makes one population vulnerable or susceptible and another more resistant.

Expanding such an approach outside the realm of fungal infections could also provide key insights for a range of infections in the future.

Indeed, the awareness of specific signals for other infections could help protect specific populations, beyond those who had general categories like underlying medical conditions, who might be more vulnerable amid any kind of outbreak.

“It’s possible that the study we are doing now with fungi could stimulate interest” in other areas of infectious disease, Del Poeta said.

He suggested that this was “pioneering work” in terms of fungal infections. At this point, his lab has produced “strong preliminary data.”

An important drug treatment side effect as a signal

This investigation arises out of work Del Poeta had done to understand why some people with multiple sclerosis who took a specific drug, called fingolimid, developed fungal infections during their drug treatment.

Del Poeta observed that the drug inhibits a type of immunity that involves the movement of lymphocytes from organs into the bloodstream.

Fingolimid mimics a natural lipid, called a sphingolipid. Del Poeta showed that this sphingolipid is important to contain the fungus Cryptococcus neoformans in the lung. When its level decreases, the fungus can move from the lung to the brain.

Indeed, Fingolimid mimics sphingosin-1-phosphate (S1P) and binds to several S1P receptors.

Del Poeta believes that the pathway between S1P and its receptor regulates the immunity against Cryptococcus. Blocking a specific receptor is detrimental for the host and may lead to reactivation of the fungus.

Putting a team together

Nathália Fidelis Vieira de Sá. Photo by Futura Convites studio

Del Poeta has been working with Iwao Ojima, a Distinguished Professor and the Director of the Institute of Chemical Biology and Drug Discovery in the Department of Chemistry at Stony Brook, to create compounds that energize, instead of block, the target of fingolimid.

Del Poeta has recruited two scientists to join his lab in this effort, each of whom has educational experience in nursing.

Nathália Fidelis Vieira de Sá, who is a registered nurse at the Federal University of Minas Gerais and a chemistry technician at Funec- Contagem City, will join the lab as a technician in the second week of September.

Fidelis Vieira de Sá, who currently lives in her native Brazil, is an “expert on collecting and analyzing organs for mice,” explained Del Poeta in an email.

For her part, Fidelis Vieira de Sá is thrilled to join Del Poeta’s lab at Stony Brook. “I’m very excited,” she said in an email. She is eager to get started because the research is “of such great relevance to public health” and is occurring at such a “renowned institution.”

Fidelis Vieira de Sá believes this is a public health issue that could have a positive impact on people with immunodeficiency conditions who need effective treatment so they live a better, longer life. When she was a peritoneal dialysis nurse, she had a few patients who had fungal infections.

“This is very serious and challenging, detection is difficult, and the life expectancy of these patients drops dramatically with each episode of infection,” she explained. 

Fidelis Vieira de Sá, who has never lived outside Brazil, is eager for new experiences, including visiting Central Park, the Statue of Liberty, Times Square, and the One World Trade Center Memorial.

As for the work, she hopes that, in the near future, Del Poeta will “be able to explain this mechanism deeply and to develop new drugs that will act on this receptor.”

Dr. Marinaldo Pacífico Cavalcanti Neto

Dr. Marinaldo Pacífico Cavalcanti Neto, who is an Assistant Professor at Federal University of Rio de Janeiro, will be arriving at Stony Brook University on August 6. Dr. Neto earned his bachelor of science in nursing and has a PhD in biochemistry from the Medical School of Ribeirão Preto at the University of São Paulo.

Del Poeta described Dr. Neto as an “expert on animal handling and genotyping,”

Dr. Neto recognizes the burden of fungal infections around the world and hoped to work with someone with Del Poeta’s credentials and experience in immunology and infection.

Understanding how cells eliminate infection, how cells might have a lower capacity to control an infection, and looking for how cells respond to treatments such as fingolimid could be a “great strategy to understand why these are so susceptible,” he said.

While Dr. Neto’s background is in immunology, he hopes to learn more about molecular biology.

Unlike Fidelis Vieira de Sá, Dr. Neto, who will live in Centereach, has worked previously in the United States. He has experience at the National Institutes of Health and at the University of California at San Diego and has been attending Del Poeta’s lab meetings from a distance for about a month.

Dr. Neto, whose interest in science increased while he watched the TV show Beakman’s World while he was growing up, is eager to work in an area where he can apply his research.

He appreciates that his work may one day “be used in the generation of protocols in a clinic.

Giancarlo Stanton. Photo from Facebook

By Daniel Dunaief

Daniel Dunaief

The outlook wasn’t brilliant for the Bronx Bombers that day

The score stood five to zero, with one inning more to play

Then when Higgy died at first, Bader raised up hopes with a double,

Judge was up next, which could have caused some trouble.

With four hits against a Rays team with spring in their gate

Yankee fans were ready for yet another cruel twist of fate.

They thought, “If only Stanton could but get a whack at that-

We’d put up even money now, with Stanton at the bat.”

But Judge flew out to left and the game was almost done

some fans took to the exits, with few having much fun

So upon that stricken multitude a grim melancholy sat,

for there seemed but little chance of Stanton getting to the bat.

But Torres drove a double, to the wonderment of all

and Rizzo singled, creating a lift upon the pall.

And when the dust had lifted, and men saw what occurred,

there was Rizzo at first, with Torres standing on third.

DJ came up next and tapped a ball towards third base

he raced to first with a determined look upon his face.

The throw from Paredes was low, allowing Torres to score.

With Rizzo at third and DJ at second, the team wanted more.

Then from the few thousand throats and more there rose a lusty yell:

it rumbled through the city, it rattled in the dell.

It pounded on the bleachers and recoiled upon the flat,

for Stanton, mighty Stanton, was advancing to the bat.

There was grit in Stanton’s manner as he stepped into his place;

there was pride in his huge bearing without a smile on his fierce face.

And when, responding to cheers, he ignored all the sound.

no stranger in the crowd could doubt ’twas Stanton who would pound.

Ten thousand eyes were on him as he twitched in the batter’s box;

five thousand tongues applauded when he rattled in his socks.

Then when the new pitcher, whose name we won’t repeat

reared back for a pitch, he planted his foot, he dug in his cleat.

And now the leather covered sphere came hurtling through the air,

and that opener was a ball, which created a chance for prayer.

The next one was low, and Stanton took a hack

The only thing moving was that behemoth’s huge back.

The next one came in high and Stanton offered at the pitch

and yet again, he missed, causing angsty fans to twitch.

With but one more to go, the mighty Stanton stood ready

would he change the script, bringing dreams of confetti?

The pitch came down the middle, in Stanton’s favorite spot

he had his chance to tie this ugly game into a knot.

The pitch was 98 and as it bore down on the plate

Mighty Stanton took a swing, that would seal his team’s fate.

For on this night in the Bronx, as a wind blew threw the stands

Fans would not be cheering or clapping their defeated hands.

No, in a season filled with losses and offensive woes galore

the beloved home team would leave them wanting more.

And so, as the days blur one into another

die hards are left with a chance to mutter.

“Our team isn’t good, they don’t score to meet their needs

they turned a glorious Cole season into a footnote in the weeds.”

One day the Bombers will be back and get those needed hits

they will crush balls to corners; they will give pitchers fits.

But for now, my friends, as the team goes gently into good nights

we can picture better games from future boys in future fights.

From left, graduate students Thomas Reilly and Hanxiao Wu with Weisen Shen. Wu and Shen are holding two of the 183 sensors they will place in the Antarctic. The team is shipping the sensors in the black container, which will travel through Port Hueneme, California and New Zealand before reaching the South Pole. Photo by Maeve McCarthy/ Angela Gruo

By Daniel Dunaief

While it’s easy to see and study materials in valleys or on the tops of bare mountains, it’s much more difficult to know what’s beneath 2.7 kilometers of ice. Turns out, that kind of question is much more than academic or hypothetical.

At the South Pole, glaciers sit on top of land that never sees the light of day, but that is relevant for the future of cities like Manhattan and Boston.

The solid land beneath glaciers has a strong effect on the movement of the ice sheet, which can impact the melting rate of the ice and sea level change.

Weisen Shen, Assistant Professor in the Department of Geosciences at Stony Brook University, recently received over $625,000 over the course of five years from the National Science Foundation to study the unexplored land beneath the East Antarctic Ice Sheet at the South Pole.

The subglacial water and hydrosystems, together with geology such as sediment or hard rocks, affect the dynamics and contribute to the movement speed of the ice sheet.

Once Shen provides a better understanding of the material beneath the ice, including glacial water, he can follow that up with other researchers to interpret the implications of ice sheet dynamics.

“We can predict better what’s the contribution of the Antarctic ice sheet to the sea level change” which will offer modelers a way to gauge the likely impact of global warming in future decades, he said.

Using seismic data

Starting this November, Shen and graduate students Siyuan Sui, Thomas Reilly and Hanxiao Wu will venture for two months to the South Pole with seismic monitors.

By placing 183 seismic nodes and installing an additional eight broad-band seismic stations, Shen and his team will quantify the seismic properties and, eventually, use them to infer the composition, density and temperature structure of the crust and the uppermost mantle.

The temperature when they place these monitors will be 10 to 30 degrees below 0 degrees Fahrenheit. They will need to do some digging as they deploy these sensors near the surface.

While the South Pole is believed to be geologically stable, signs of sub-glacial melting suggest the crust may bear a higher concentration of highly radioactive elements such as uranium, thorium and potassium.

Those natural elements “produce heat all the time,” said Shen. 

The process and analysis of seismic waves works in the same way it would for the study of a prism. Looking at the refraction of light that enters and leaves the prism from various angles can help researchers differentiate light with different frequencies, revealing clues about the structure and composition of the prism.

Earth materials, meanwhile will also cause a differentiation in the speed of surface waves according to their frequencies. The differentiation in speeds is called “dispersion,” which Shen and his team will use to quantify the seismic properties. The area has enough natural waves that Shen won’t need to generate any man-made energy waves.

“We are carefully monitoring how fast [the seismic energy] travels” to determine the temperature, density and rock type, Shen said.

The water beneath the glacier can act like a slip ’n slide, making it easier for the glacier to move.

Some large lakes in Antarctica, such as Lake Vostok, have been mapped. The depth and contours of sub glacier lakes near the South Pole, however, are still unclear.

“We have to utilize a lot of different methods to study that,” said Shen.

The Stony Brook researcher will collaborate with colleagues to combine his seismic results with other types of data, such as radar, to cross examine the sub ice structures.

The work will involve three years of gathering field data and two years of analysis.

Educational component

In addition to gathering and analyzing data, Shen has added a significant educational component to the study. For the first time, he is bringing along Brentwood High School science teacher Dr. Rebecca Grella, A PhD graduate from Stony Brook University’s Ecology and Evolutionary Biology program, Grella will provide lectures and classes remotely from the field.

In addition to bringing a high school teacher, Shen will fund graduate students at Stony Brook who can help Brentwood students prepare for the Earth Science regents exam.

Shen is working with Kamazima Lwiza, Associate Professor in the School of Marine and Atmospheric Sciences at Stony Brook, to bring Earth Science, including polar science, to schools in New York City and on Long Island with a bus equipped with mobile labs.

Lwiza, who is the Principal Investigator on the EarthBUS project, will work together with Shen to build a course module that includes a 45-minute lecture and exhibition.

Shen feels that the project will help him prepare to better educate students in graduate school, college, and K-12 in the community.

He feels a strong need to help K-12 students in particular with Earth Science.

As for students outside Brentwood, Shen said he has an open door policy in which the lab is receptive to high school and undergraduate students who would like to participate in his research all year long.

Once he collects the first batch of data from the upcoming trip to the South Pole, he will have to do considerable data processing, analysis and interpretation.

While Shen is looking forward to the upcoming field season, he knows he will miss time in his Stony Brook home with his wife Jiayi Xie, and his four-and-a-half year old son Luke and his 1.5 year old son Kai.

“It’s a huge burden for my wife,” Shen said, whose wife is working full time. When he returns, he “hopes to make it up to them.”

Shen believes, however, that the work he is doing is important in the bigger picture, including for his children.

Record high temperatures, which are occurring in the United States and elsewhere this summer, will “definitely have an impact on the dynamics of the ice sheet.” At the same time, the Antarctic ice sheet is at a record low.

“This is concerning and makes [it] more urgent to finish our work there,” he added.

METRO photo

By Daniel Dunaief

Daniel Dunaief

They found me.

After several decades without my civil service responsibilities cropping up, I recently received a summons to appear for jury duty.

The summons brought back memories of a jury I served on years ago. While I was sitting in the courtroom waiting as a court officer chose names of potential jurors for a criminal case, a woman sitting next to me asked my name. When I told her, she said I’d be picked for that jury.

I smirked because there were 200 of us in the room.

Two names later, they called me. I looked back quizzically at the woman, who smiled and walked out of the room with the others who weren’t called.

I served on that jury. It was a buy and bust drug case. I listened carefully as the defense attorney questioned the under cover police officer who tried to buy drugs from the defendant.

When the defense attorney asked how many such operations the policeman had been on, the number was high enough to raise questions about how well he remembered this defendant.

The officer said he made notes, which the defense attorney asked him to read. Going through the notes, he described someone who was about the same build and age as the defendant. He also described a leather jacket with a specific insignia. That was not the defense attorney’s finest moment, as the defendant was wearing that exact same jacket to court. Whoops!

The rest of the trial wasn’t particularly memorable. On closing, the defense attorney suggested that the defendant became addicted to drugs when he served in Vietnam. The judge asked us to focus only on whether the defendant broke the law and not on how he might have gotten addicted to drugs.

After the judge sent us to deliberate, the foreman suggested that we take a vote. Who thought the man had drugs in his possession?

Every hand shot up.

Who thought he intended to sell those drugs?

Everyone but one person agreed.

We asked her about her concerns. She said she had ordered lunch and wanted her hamburger and fries. We told her we’d be happy to pitch in and give her money for a lunch if that was the only reason she wasn’t voting to convict.

Was that, we wondered, paying her for a verdict?

It didn’t matter. She wanted to wait. When lunch came, we ate quietly, waiting for the moment we could take another vote. The holdout said the burger wasn’t good and the fries were soggy.

Gnashing our teeth, we voted again. This time, we all voted to convict. One of the other jurors asked her if she had any other concerns or questions. She shook her head.

When we knocked on the door to let the officer know we were ready, he told us to wait. We spent another three hours in that room.

We returned to the courtroom, where the foreman announced our verdict. The defense attorney polled us all on both counts.

Once we were out in the hallway, I asked the prosecutor why we had to wait so long. She said the judge had held them in the courtroom, figuring that we’d have a verdict before lunch. When he heard we broke for lunch, he told everyone to leave and return in an hour.

Everyone but the defendant came back. The defense attorney spent the next few hours calling his relatives and trying to bring him back.

“What’s going to happen?” I asked.

The police would go to his residence and there would be a warrant for his arrest. He would also enter a database. How hard, I wondered, would the police search for him?

She suggested they would look, but that he was more likely to be caught committing another crime.

“He’s out because someone wanted a soggy burger?” I asked.

She shrugged.

With cell phones and an electronic footprint, the system today may work better than it did then.