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Stony Brook University

SBU graduate student and grand niece of world renowned anthropologist Richard Leakey, Acacia Leakey, draws a sketch of huts in the village of Ambodiaviavy, Madagascar as the children look on. Photo from Mickie Nagel

By Daniel Dunaief

 

Mickie Nagel recently returned from the island nation of Madagascar, and she’s filled with ideas, inspiration, observations and opportunities. One of the three founders of a new nongovernmental organization called BeLocal, the Laurel Hollow resident spent several weeks with Stony Brook University graduate students Leila Esmailzada and Acacia Leakey taking videos and gathering information about life in Madagascar.

The goal of the new organization is to share this footage and insight with undergraduate engineers at SBU, who might come up with innovations that could enhance the quality of life for the Malagasy people.

In one village, a man showed her a three-inch lump on his shoulder, which he got by dragging a long stick with bunches of bananas that weigh over 100 pounds along a clay footpath out of the forest. People also carry rice that weighs over 150 pounds on their heads, while many others haul buckets of water from rivers and streams to their homes while walking barefoot.

In addition to transportation, Nagel also found that villagers around Centre ValBio, a Stony Brook research station, had basic food and water needs. Over 17 years ago, another group had installed four water pumps in a village to provide access to water. Only one pump now works.

SBU graduate student Leila Esmailzada helps villagers in Ambodiaviavy, Madagascar, clean rice. The job is usually delegated to the children who pound the rice for 30 minutes. Photo by Mickie Nagel

As for food, some villagers in Madagascar spend hours preparing rice, including beating off the husks and drying the rice. They store this hard-earned food in huts that are often infiltrated with rats, who consume their rice and leave their feces, which spreads disease.

Traveling with Esmailzada and Leakey, Nagel not only helped document life in these villages but also searched for information about available resources to drive engineering innovations, while Leakey gathered information about an invasive species of guava.

“Ideally, if any projects require wood, then they should incorporate guava sticks into their design, as opposed to planks from forest trees,” explained Leakey in an email sent from Madagascar. The graduate student, who recently earned her bachelor’s degree at Stony Brook, will be recording the average thickness of the stems, the average length of a straight piece and the load capacity of the branches. Leakey plans to return from the African continent in the beginning of August.

Leakey also visited metalworkers to explore the local capacity. The raw materials come from scrap metal dealers, who often get them from old car parts.

Nagel started BeLocal with her husband Jeff Nagel and a classmate of his from their days as undergraduates at Carnegie Mellon University, Eric Bergerson. Indeed, BeLocal fulfills a long-standing goal of Jeff Nagel’s. Before freshman year in college, Nagel told Bergerson that he wanted to do something that had a positive impact on the world.

While the founders have contributed through their work, their jobs and their families, they found that partnering with Stony Brook University and Distinguished Professor Patricia Wright in Madagascar presented a chance to have a meaningful impact on life on the island nation.

Nagel, whose background is in marketing, visited Madagascar over two years ago, where she traveled for over a hundred hours on a bus through the country. “You just see people living below the poverty line and you see how that plays out in normal day-to-day activities,” she said. “You see a young mom carrying a child on her back and one on her front, with heavy produce on her head and you just think, ‘Wow, there has to be an easier way for some of this.’”

Mickie Nagel, far right, on an earlier trip to Central ValBio with her daughters Gabrielle, far left, and Lauren, center. when they first visited Centre ValBio. Photo by Heidi Hutner

When Nagel returned from her initial trip to Madagascar with her daughters Gabrielle, 18, and Lauren, 17, she and her husband thought people around the world would likely want to help but that not everyone could afford to travel that far.

Nagel recalls Bergerson, who is the director of research at the social data intelligence company Tickertags, telling her that they “don’t have to travel there. You can videotape the daily challenges and crowd source” innovations.

That’s exactly what Leakey and Esmailzada did for the last few weeks. Leakey said she is looking forward to working with senior design students as they go through their projects at Stony Brook and is eager to see how they understand the situation “through the footage and pictures we collect.”

The BeLocal approach isn’t limited to Madagascar, the BeLocal founders suggested. Indeed, given the distance to an island famous for its lemurs, animated movies and an Imax film that features primates with personality, BeLocal could have started in a Central American country like Belize.

Mickie Nagel, however, urged them to start at a location where they would immediately have the trust of local residents. That, she suggested, came from the over quarter of a century of work from Wright, an award-winning scientist who has not only helped preserve Ranomafana [National Park in Madagascar] but has also helped bring health care and education to the villages around the CVB research station. Wright and the Malagasy people have a “mutual respect for each other,” Nagel said.

“People have been exceptionally warm and welcoming,” Leakey said. Getting people accustomed to the presence of cameras hasn’t been straightforward, as people sometimes stop what they are doing, but the guides have helped make the villagers more comfortable.

Jeff Nagel, who works at a private equity firm in New York City, explained that Madagascar is the first step for BeLocal. This effort “can be expanded to other countries or other areas,” Nagel said. “It doesn’t have to be engineers and universities,” but can be instituted by creative people everywhere.

At this point, BeLocal is not looking for any additional funding but might consider expanding the effort at this time next year. Nagel said this fall, they will look for professional engineers to advise on projects. “We would like people who are interested in participating or just keeping up with developments to come and register on our website, www.BeLocalgrp.com,” she suggested.

The site, which the group is upgrading, is up and running. Bergerson explained that they have a “lot of infrastructure to build on” to create the crowd sourcing platform.

Jeff Nagel suggested that this effort is designed to use technology constructively. “Technology’s job, first and foremost, is to help humanity,” he said. “This is a chance to use it in a way that matters to people.”

Staff members of WUSB-FM Radio gather in the Media Suite in the Student Activity Center at Stony Brook University for a photo. Image courtesy of WUSB

By Norman Prusslin

Long Island radio listeners scanning the FM dial 40 years ago this coming Tuesday were surprised to hear musical stirrings on the 90.1 frequency that had previously offered static or sounds of distant stations. It was on Monday, June 27, 1977, at 5:30 p.m. that the Stony Brook University radio station joined the community of Long Island radio stations. I had the honor of coordinating the team that brought the station to the air that day and then went on to serve as the station’s general manager for 28 years.

Norman Prusslin

Looking back on that first day of broadcasting, it is fascinating to think about how much the media landscape has changed over the past 40 years.  In 1977, FM radio audience listening was just about ready to overtake the decades-old primacy of AM radio. Cable television on Long Island was in its formative years … CNN and MTV were still three and four years away, respectively. Music-oriented radio stations played vinyl on turntables while public service announcements aired on tape cartridges, and long-form public affairs programming was recorded on cassette and reel-to-reel audiotape.

How times have changed!

Through the compact disc and personal computer revolutions of the early 1980s to the web, streaming and digital download innovations of the 1990s to today’s multiple music distribution systems, WUSB has been at the forefront of marrying new technology with public service mission and responsibility.

The station was put to the test and earned its community service stripes eight months after sign on. Longtime North Shore residents will remember the crippling ice and snowstorms of February 1978. The Stony Brook campus was closed for a week. This was a time before wide cellphone use and way before the internet brought information to us, at a moment’s notice, anytime and anywhere.

WUSB was the main outlet in our area for getting critical safety information out to the community. Students and community volunteers slept in the studio to make sure the station provided a 24-hour service.

It was a crash course in local, person-to-person community radio programming. A lesson plan that has been used by the hundreds of student, staff, faculty, alumni and community volunteers who have sat in the on-air chair for 40 years.

Students covered the Shoreham nuclear power plant protests of the late 1970s live from the site. A radio play, “Shadow Over Long Island,” followed the template of “War of the Worlds” in focusing attention on the issue of nuclear power on Long Island while at the same time giving students a history lesson in producing “old time radio drama.”

WUSB received national attention (Time magazine and NBC News) when student staff produced and hosted the 1984 Alternative Presidential Convention on campus. While the two major party candidates, incumbent President Ronald Reagan and Walter Mondale did not attend, over 30 “legally qualified candidates” did providing the campus and local community with a day-long “teach in” of debate, conversation and organizing.

In the music industry, the late 1970s have been recognized as the time when the influence of college radio stations to introduce new and developing genres to radio listeners took hold. In the years before music video, satellite radio, Facebook, YouTube, iTunes, Pandora and Spotify, college radio was THE broadcast outpost for new music.

WUSB was the Long Island radio home for artists of all musical stripes. The music of major label and independent artists from the worlds of rock, folk, blues, classical, hip-hop, dance, traditional and more was being heard, often for the first time, by Long Islanders over 90.1 FM.

I am perhaps most proud of the role WUSB has had in developing an active local music scene and community. From hosting the first Long Island Contemporary Music Conference in the early 1980s to developing collaborative partnerships with area nonprofit music and arts organizations and concert clubs and venues of all sizes, WUSB’s status as a key player in the Long Island music community has brought recognition and honors to the university. It is therefore no surprise that the first meetings that led to the creation of the Long Island Music Hall of Fame in 2003 were held on campus.

This coming week, we celebrate 40 years of 24 hours/day noncommercial radio programming created by a volunteer staff of students, faculty, alumni and community members varied in background and political persuasion and perspective. It’s a time to recognize volunteers coming together for the common mission and purpose of presenting intelligent and thought-provoking dialogue, music from all corners of the globe and campus-focused programming via live sports coverage, academic colloquia and event announcements and coverage.

Now is no time to rest on past laurels. Earlier this year, the station moved into new studios in the West Side Dining Complex and added a second broadcast signal at 107.3 FM to better increase service coverage to North Shore communities.  On June 27, 1977, at 5:30 p.m., founding members of the WUSB station staff coined the expression “….the experiment continues.”

40 years on, it still does!

Norman Prusslin is director of the media arts minor at Stony Brook University. He is WUSB-FM’s founding general manager serving in that position until 2006 and continues his association with the station as its faculty adviser.

By Bill Landon

A late Long Island-hit drew a penalty, leaving New York City with an even bigger advantage with two seconds left on the clock in the 22nd annual Empire Challenge football game. Monsignor Farrell kicker Paul Inzerillo tried to draw Long Island offsides without success, but just ahead of a delay of game flag, sent the ball flying as the clock ran down to zero, and nailed the 32-yard field goal attempt to snatch a second straight NYC victory, 37-35, from Long Island. The June 21 loss marks the second year in a row Long Island lost in dramatic fashion at Hofstra University’s James M. Shuart Stadium.

“That penalty hurt us,” Elwood John Glenn wide receiver Damien Caffrey said. “But to play in this game is a dream come true.”

“That penalty hurt us, but to play in this game is a dream come true.

—Damian Caffrey

A Long Island interception led to NYC’s first touchdown of the game, with four minutes left in the opening quarter. But Ward Melville senior John Corpac received a pass from Long Island quarterback Aaron Ruthman, of Elmont, and bolted down the right sideline for the touchdown. Christian Carrick added the extra point to tie the game, 7-7.

NYC took the lead with the team’s second touchdown of the game, but the kick failed, and left Long Island with a chance to pull ahead. Ward Melville wide receiver Dominic Pryor, already looking comfortable on his new field, where he will instead though play lacrosse next year, was found twice for big yardage. The first connection was for 18 yards to NYC’s 40-yard line and the second, was for 28 yards to the 5. Two plays later, Farmingdale running back Jordan McLune took advantage of that opportunity by capping of a six-play, 58-yard drive, and Carrick’s kick gave Long Island the lead, 14-13, with 7:14 left in the first half.

Unfortunately, the lead was short-lived as NYC scored another touchdown, put the 2-point conversion play failed.

“It’s tough to come out and play football in June, but I was so motivated to come out here and play with such great athletes, and play my hardest,” Pryor said. “[NYC is] just a hard-nose team with great athletes.”

It looked like a Ward Melville football game from there on out though, as Pryor, who caught give passes for 89 and two touchdowns, scored his first on a 24-yard pass from Elmont quarterback Aaron Rutgman on fourth-and-seven.

Pryor got the call again on the next score, as the Ruthman-Pryor tag-team connected on a 17-yard pass. Carrick’s kick lifted Long Island to a 28-19 advantage.

“[This game] it’s just something that I’m blessed to be in,” Pryor said. “It’s a great event with everything that it stands for, and I’m glad to be a part of it.” Prior to Wednesday’s game, no Patriots had played in the Empire Challenge. With cornerback Eddie Munoz also on the field, it put not two, but three Patriots in the Empire Challenge for the first time.

“[This game] it’s just something that I’m blessed to be in. It’s a great event with everything that it stands for.”

—Dominic Pryor

But New York, held to 17 yards in the second half until midway through the fourth quarter, exploded for a five-play, 75-yard drive that was capped by a 45-yard touchdown from Christian Anderson to Seba Nekhet. The PAT made it 28-26 with seven minutes left in regulation. NYC’s defense forced Long Island to punt from deep in its own end and the city took advantage of the favorable field position to score on Siddiq Muhamad’s 12-yard run that made it 34-26. The special teams completed a 2-point conversion that brought the score to 36-28.

Corpac continued the strong Ward Melville showing as he handled another punt return 83 yards, going coast-to-coast to tie the game.

“I was telling my teammates on the sidelines: ‘I gotta take this one back,’” Corpac said. “’I got to do it.’ And sure enough, I saw the hole and I took it.”

Carrick, who was perfect on the evening, put Long Island ahead with 2:44 left in the final quarter.

NYC threw the ball out of bounds to stop the clock, and got a gift when Long Island was flagged for a late hit. The 15-yard penalty brought NYC to Long Island’s 22-yard line.

“I was scared leading by a point with eight seconds left,” Caffrey said. “It was pretty crazy, because their offense is really good. They brought it to a whole new level.”

Corpac, who is bound for Stony Brook University’s football team in the fall, echoed his longtime teammate-s sentiment of the significance of the Empire Challenge.

“[To play in this game] — it’s a great honor,” he said. “It’s the best way I could ask to end my high school football career.”

Republicans Phil Boyle and Larry Zacarese and Democrat Dan Caroleo are running for Suffolk County sheriff. Photos from left, from Phil Boyle, Larry Zacarese and Suffolk Democratic Chairman Richard Schaffer

Three candidates are currently in the race to become Suffolk County sheriff this November. State Sen. Phil Boyle (R-East Islip), career law enforcer Larry Zacarese (R), Boyle’s Republican primary challenger, and retired New York City police officer Dan Caroleo (D) are each hoping to inherit the position held for 12 years by Vincent DeMarco (R), who announced in May his decision not to seek a fourth term. He declined to comment on his decision.

Boyle, 55, of Bay Shore, who was elected to the New York Senate in November 2012 after serving 16 years as a state assemblyman, was endorsed for sheriff by the Suffolk Conservative Party in March and was backed by both the Republican and Independent parties soon after.

If elected, Boyle, a stepfather of two, said he wants to run the sheriff’s office in the most cost-effective manner possible, promote people based on merit rather than politics and halt the rise of drug overdoses and gang violence. He recently co-sponsored a bill to ban the sale of machetes to minors, the weapon of choice for MS-13 gang members.

The senator, who chaired and helped create the state Senate’s Joint Task Force on Heroin and Opioid Addiction in 2013 to stamp out the growing drug problem, pointed to his active involvement pushing law enforcement issues in Albany as significant qualifiers.

Under the task force, 18 hearings were held across the state, which led to 11 prevention, treatment and enforcement measures passed by the Legislature and signed into law by Gov. Andrew Cuomo (D).

When it comes to immigration issues, Boyle said he disagrees with how DeMarco has run the jail.

“I work closely with federal immigration agents to make sure any individuals housed in the Suffolk County jail that agents may want to interact with due to immigration status have access to that,” Boyle said. “DeMarco, for a while, made the jail a sanctuary jail, in my opinion, and I’m definitely not going to allow that to happen.”

Zacarese, 43, of Kings Park, who is currently the assistant chief of  the Stony Brook University police, said he’s looking forward to the primary. Zacarese and his “army of volunteers” are currently gathering 2,000 signatures in order to run. Confident he’s not just another choice, but the better choice, for the top law enforcement job, Zacarese outlined his 25-year law enforcement career.

He started as a Holbrook volunteer fireman at 17, went to paramedic school, then began to work in the NYPD as a patrol officer, canine handler and tactical paramedic. He became a sergeant, then deputy chief fire instructor at the Suffolk County Fire Academy and an adjunct lecturer at John Jay College of Criminal Justice and Stony Brook University.

For four years, while working at Stony Brook by day, Zacarese pursued his shelved passion, attending law school by night. He is currently admitted to practice law in the state.

“My wife tells me I’m the biggest underachiever she knows,” the father of four said, laughing. “I’ve worked really hard rounding out all of the areas that are pertinent to the office of sheriff, which is much more than just the person who oversees the correctional facilities.”

He said, if elected, his main priority is the opioid crisis.

“We really need to take a better look at the prevention and collaboration between addiction programs and not-for-profits, as well as how we can influence treatment while people are being incarcerated,” he said. “It’s about [providing] help while they’re in jail so when they return to their communities, they have started on the path to recovery.”

Suffolk County Democratic Committee Chairman Richard Schaffer, campaign manager for Caroleo, 62, of North Babylon, who was unavailable for comment, said the former New York City police officer, director of security at the North Babylon School District and current member of the district’s school board has, “a wealth of experience, he’s well-rounded and I think he can work cooperatively with, and continue, what County Executive Steve Bellone (D), Suffolk County Police Commissioner Tim Sini, and DeMarco have laid out — making sure we continue to drive down jail population.”

According to Schaffer, “Caroleo feels he has a great deal of public safety experience” that he could bring to the sheriff’s department.

Three Village Chamber of Commerce executive director, David Woods, has been a member of the organization for nearly 10 years. Photo from David Woods

By Jenna Lennon

During his time with the Three Village Chamber of Commerce, executive director David Woods is most proud of the new signs welcoming people to the Three Villages and Stony Brook University, placed around the community and  along Nicolls Road.

“Before they went up, I can remember, for example, one of the former directors of the university hospital was talking at one of the chamber meetings, and he said that it had taken him an hour and a half to get from the airport to the university,” Woods said in a phone interview.

The former university hospital director flew into the airport in Islip, just twenty or so minutes from Stony Brook, but he drove around for another hour trying to find the university and its community, according to Woods.

“One of the things that I never would have thought of is putting up a sign like that because in the days where I first came to the community to work for the university, there was a sort of invisible fence between the campus and the community,” Woods said. “There would have been opposition. And those beautiful signs have helped a lot.”

Now after nearly 10 years with the chamber, Woods is retiring on June 30 at the end of the organization’s fiscal year.

Charles Lefkowitz, vice president of the Three Village Chamber of Commerce, worked with Woods nearly his entire time with the chamber.

Woods has “a unique style and passion to bring the business community together. He was never afraid to try something new or even borderline what would be deemed outrageous,” Lefkowitz said.

Woods started with the chamber after retiring from the “regular work world” and having just finished his novel “Buffalo Snow Day” — “a sort of comic novel about Buffalo turning into Aspen.”

Woods spent 17 years as assistant to the president at Stony Brook University. For 20 years after that, he worked in Manhattan “in marketing communications as secretary of the New York City Press Club, the Deadline Club, doing things like introducing the hit board game Pictionary and then an unknown new radio talk show host, now for better or worse a household name, Rush Limbaugh.”

When the chamber needed a manager, they called Woods.

“It was, still is, a great job because we were sitting here like ships passing in the night, our historic community on one side of the railroad tracks, Stony Brook University making new history on the other side and convergence clearly needed,” Woods said. “Since then, leaders on both sides of the tracks have been bringing our two worlds together and doing a lot of it at the monthly chamber meetings.”

Andy Polan, chamber president alongside Woods for the last four years said Woods’ “historical knowledge of the community is pretty amazing from the university to the local history.”

Polan is looking to fill the vacancy with someone who is outgoing, social media-savvy and “interested in developing the chamber to grow to our next level.”

Woods and his wife, Desiree, are taking some time off to go upstate to his hometown of Dunkirk on Lake Erie with their daughter and granddaughter for a family reunion.

Woods will keep in contact with the chamber and continue to support the new director for the upcoming 18th annual chamber beach barbecue, a networking event in July.

For now, Lefkowitz will miss Woods’ “smile and grin at the other side of the table.”

Interested applicants for the executive director position with the Three Village Chamber of Commerce should send their resumes to [email protected].

Dr. Jennifer Arnold leads the Parade of Survivors. Photo by Cindy Swanson

By Heidi Sutton

On Sunday, June 4, hundreds of thousands of people gathered in various locations across the country for National Cancer Survivors Day, a celebration of life for anyone who has been touched by cancer. Locally, the Stony Brook Cancer Center hosted its 13th annual event, made possible by sponsorship from the Stony Brook School of Medicine and Stony Brook University.

The weather cooperated as attendees participated in a variety of outdoor activities, such as the popular dunk-a-doc, bedpan golf, chemo bag toss and face painting, as well as musical entertainment. The day culminated with the Parade of Survivors to the tune of Journey’s “Don’t Stop Believing.”

Dr. Yusuf Hannun

“There is really no activity that I look forward to more every year than what we are doing here today, to celebrate you and to celebrate survivorship,” said Dr. Yusuf Hannun, director of the Stony Brook Cancer Center, to a crowd of survivors, doctors, nurses, family members and friends. “Looking around … I am really humbled to see how this event has been growing exponentially, from very modest beginnings of a handful of dedicated volunteers and determined survivors, to today with over 1,300 [attendees], 300 of them survivors,” he said.

Hannun also took the opportunity to speak about the new 245,000 square-foot, state-of-the-art Medical and Research Translation (MART) building, which served as the backdrop to the event and is scheduled to open by the end of this year. The director stated the new facility “will allow us to serve twice as many patients and their families … and allow us to continue to push back against cancer at all times. We are very excited to move into that building.”

The keynote speaker of the day was Dr. Jennifer Arnold, who is featured on TLC’s docudrama, “The Little Couple” along with her husband, Bill, who is originally from Port Jefferson Station, and their beautiful children, Will and Zoey. The show has served as an invaluable way to break down barriers and educate the public about people with disabilities.

Dr. Jennifer Arnold

Standing at just 3 feet and 2 inches, Arnold was born with a rare type of dwarfism called spondyloepiphyseal dysplasia, Strudwick type and has undergone over 30 surgeries in her lifetime. In 2013 she was diagnosed with stage 3 choriocarcinoma, a rare cancer that developed after a non-viable pregnancy. She graciously chose to share her fight with viewers of her show.

Now a three-year cancer survivor, Arnold shared her journey and personal lessons learned at Sunday’s event with a dynamic, motivational and inspirational presentation titled Surviving with Grace and received several standing ovations.

“Although I had a lot of life lessons [growing up], nothing taught me more than going through cancer,” said Arnold. “Sometimes life throws a wrench into the middle of your world and you have to be ready for that because life is short, no pun intended.”

“Going through chemotherapy changes you a lot, physically, emotionally, mentally…,” she said. After chemo, “I didn’t go back to normal, but I did go back to life. Truly it takes a village to go through your treatment and survivorship. It’s okay to accept that help.”

Arnold continued, “This is a wonderful life that we have and I am so blessed to be alive and to be able to share my story and I know that many of you in the audience feel the same way. … Whether it’s the fact that you’ve undergone treatment for cancer or whether you’ve had other obstacles in life, I hope that you too can overcome those obstacles and that you can survive with grace.”

Gabor Balazsi in his lab. Photo by Aleksandrs Nasonovs

By Daniel Dunaief

It started with a bang. When he was young and living with his parents, Gabor Balazsi’s curiosity sometimes got the better of him, at the expense of his parents’ house.

The future Henry Laufer associate professor of physical and quantitative biology at Stony Brook University was holding bare wires in his native home in Transylvania when he plugged in an appliance. The current surged through his body, preventing him from releasing the wires. Fortunately, his mother came in and “unplugged me.”

These days, Balazsi, is much more focused on the kinds of behavior that turns the instructions for a cell into something more dangerous, like cancer or a drug-resistant strain of a disease.

Balazsi recently received a $1.8 million, five-year grant from the National Institutes of Health to study how gene networks change, often to the detriment of human health, as is the case when they are active in cancer or when they are resisting treatment. The grant is called Maximizing Investigators’ Research Award.

“Cancer cells often don’t look the same in a matter of months and drug-resistant microbes may look the same in a matter of days,” Balazsi said. He would like to know “what causes them to change and how can we prevent them from changing to their advantage and our disadvantage?”

In a way, Balazsi is trying to figure out a code that is akin to the popular 1970s game Simon in which a player has to repeat a growing number of flashing lights and sounds. With each turn, the game increases the number of flashing lights and sounds, going from a single red, to red, green, yellow and green until the player can no longer recall the entire code.

He is looking for a similar key to a sequence of events that transforms a cell, except that in the cancer, there are millions of interacting lights, many of which are invisible. The cancer biologist tries to reconstruct the sequence in which some of these lights turned on by observing visible lights that are currently on.

He is exploring the “pattern that leads to the outcome” through changes of networks in yeast cells, he said. He is also hoping to explore pathogenic fungi. The pattern, he said, will change depending on the circumstances, which include the environment and initial mutations.

Scientists who have collaborated with Balazsi suggested his understanding of several scientific disciplines enables him to conduct innovative research.

“He bridges two fields, biology and biophysics, allowing him not only to describe biological processes but also to model them and make predictions that can then be tested,” Marsha Rosner, the Charles B. Huggins professor at the University of Chicago, wrote in an email.

While Balazsi doesn’t treat patients, he is focused on understanding and controlling the processes that lead a cell or group of cells to change from a uniform function and task to a heterogeneous one, where the cells may follow a different path using a previously inactive network of genes.

By understanding what causes these changes, he hopes to find ways to slow their progress or prevent the kind of deviations that lead to combinations that are destructive to humans, such as when the cellular machinery copies itself uncontrollably.

Balazsi and Rosner collaborated on one paper and are continuing to work together. “Our work demonstrates one mechanism by which cells move from a homogeneous population to a more complex population that contains cells that promote cancer,” Rosner explained. “This mechanism is not based on mutations in genes, but rather on changes in the way that genes interact with each other in cells.”

On a fundamental level, Balazsi explained that researchers have developed considerable understanding, but still not enough, of what happens in normal conditions. He is seeking to discover the logic cells use to survive under stressful conditions.

Balazsi would like to determine if there is “anything we can do to decrease the tendency of cells to deviate from normality,” he said.

Balazsi welcomes this new funding, which will give him the freedom to pursue research questions at a basic level. Instead of supporting a single project, this financial support contributes to multiple projects.

The next step in funding his lab will be to approach the National Cancer Institute. Without much experience in applying for cancer grants, Balazsi plans to attend a think tank workshop in June in Seattle. Attendance at this meeting, which is hosted by Sage Bionetworks and the NCI, required an application and selection of participants.

To some degree, Balazsi may be able to relate to the heterogeneity that he hopes to study in cells. A physicist by training, Balazsi explained that he “wandered into biology.” He would like to steer away from major trends that mobilize many researchers. If many people are working on something, he does not want to be enriching big crowds but would prefer to try new things and test new ideas.

A resident of East Setauket, Balazsi lives with his wife Erika and their daughter Julianna, who is 6. Julianna is already doing some experiments at home and is exploring the yard.

When Balazsi was young, his parents tried to encourage him to become a doctor, which didn’t work because he didn’t like blood or hospitals as a child. In addition to his unexpected electric shock, Balazsi also explored how ethanol burns while flowing, which caused some additional damage to his house. “My parents,” he recalled, “weren’t happy.”

As for his work, Balazsi would like his work with these first steps, in understanding cellular processes, will have a translational element for people some time down the road.

“Whatever we do, hopefully, they can be implemented in actual cancer cells that are coming from patients one day,” he said, or they could have some relevance for people who are attempting to fight off “pathogenic microbes.”

Fan Ye. Photo from SBU

By Daniel Dunaief

Fan Ye has a vision for the future filled with high service and efficiency that doesn’t involve butlers or personal attendants. The assistant professor of electrical and computer engineering in the College of Engineering and Applied Sciences at Stony Brook University is focused on creating smart environments in which window blinds open as people pull into their driveways, lights turn off in unoccupied rooms and the building guides a new student turn by turn through complex floors and hallways from entrance to the registrar’s office.

“The physical environment would be like a caring mother,” said Ye. It would sense and figure out people’s needs and “take care of the occupants inside the building.”

In Ye’s vision, which he estimates is about one year to decades away from a reality, objects that rely on people to turn them on or off, reposition them or alter their settings would have chips embedded in them, working together to create an environment that anticipates and learns in response to the need around it.

“With sensors, [a smart environment] can sense both physical conditions and human activities and adjust the environment in manners that create/improve comfort, safety, convenience” and the productivity of the occupant, he explained in an email.

Ye recently received a $450,000 award over the next five years from the National Science Foundation for early-career faculty for his study of smart environments. The prestigious award is the highest honor given by the government to scientists and engineers beginning their independent careers.

Initially, Ye is developing and testing a security system with the Stony Brook University Police Department and the Center of Excellence in Wireless and Information Technology that grants specific access to buildings or facilities depending on the specifications of an administrator.

Many of the buildings on campus have electric locks, which someone can open with a badge where there’s a badge reader. A badge, however “isn’t that flexible,” Ye said. If an administrator would like to grant someone one-time access to open a door that doesn’t provide ongoing access, that is difficult to do with a badge system.

“What’s lacking in this closed proprietary system is flexible access control, which can determine who has what access based on context factors,” he said. Ye, his team, the police department and the CEWIT are building a system that can enable greater flexibility that allows someone to open an office door for five minutes during a specific hour. “If any of these context factors is not satisfied, they don’t have access,” he said.

Ultimately, he would like to construct a system using modern mobile technology, like smartphones, instead of physical badges. The system would include embedded security that employs modern cryptography so a hacker or attacker can’t trick the system.

By using software and hardware security, Ye is hoping to develop a system that prevents the most common attacks at a reasonable cost, which he hopes would prevent someone from gaining access.

Ye is building real systems and testing them. The cost-benefit of these systems depends on the object. A motor to open and close a window would cost money to manufacture, install and operate. As with any technological innovation, he said, “the question comes down to, How do you invest versus how much do you get in return?”

Looking at the historical trend for computation resources, Ye said computing and storage costs are falling at an exponential rate, while the price for radio and sensing is also falling rapidly, although not at the same pace.

“I believe this trend will continue, especially for a lot of these objects that need small embedded systems” that can be manufactured at a scale with low cost, he continued. The process of turning the environment into an efficient, high-service system isn’t an all-or-nothing proposition. Consumers might decide to focus on the air-conditioning or heat use in their homes.

Other researchers are developing ways to harness the vibrational energy of movement or sound, which, conceivably, could power some of these electronics without requiring the delivery and consumption of more energy.

Ye recognizes that these parts can and will break down and require repair, just as dishwashers sometimes stop working and iPhones can lose a list of contacts. So many small electronic parts in a smart environment could seem like an invitation to malfunctions.

He likens the repair process to cloud computing, which allows small to medium-sized companies to rent computing resources from larger companies. “A smart environment, especially for public buildings like a university or office, could potentially run in a similar model,” he said. Individuals might rely on IT support from dedicated personnel who, like a superintendent in a building, could be responsible for a host of smart products.

A native of Hubei Province in China, Ye, who now lives in Setauket, loves to hike in national parks. His favorite is Canyonlands in Utah. Ye had worked at IBM for about 10 years before joining Stony Brook almost three years ago. While he was there, Ye worked on numerous projects, including distributed stream processing, cloud-based queueing and wide-area dependable messaging. “I learned tremendously at IBM,” he said.

Ye is “”well known and respected in the mobile and wireless computing research community,” Hui Lei, an IBM distinguished engineer, wrote in an email. “He conducted pioneering work on scalable message delivery, robust coverage and security in wireless sensor networks, which are well received and highly cited and closely related to the smart environment work he is doing now.”

Lei suggested that Ye’s experience and accomplishments provide him with a solid track record and he is “confident that [Ye] will be able to come up with innovative solutions in this area.”

 

Elected officials, religious leaders, volunteers and residents gathered at the Long Island State Veterans Home on the campus of Stony Brook University May 26 to give thanks to a roomful of United States military veterans. The annual ceremony, which includes a color guard, firing detail and wreath laying, honors the brave men and women who made the ultimate sacrifice for their country — whose brothers and sisters in arms reside at the home on campus.

The Long Island State Veterans Home is dedicated to serving the more than 250,000 veterans who live on Long Island. Opened 26 years ago, the facility’s relationship with Stony Brook University’s medical department has been a winning combination for the care of veterans — providing skilled nursing services that many veterans wouldn’t otherwise have access to.

Veterans who fought in Vietnam, Korea and even World War II sat together in the home’s Multipurpose Room, some of them tearful as singer Lee Ann Brill performed moving renditions of “Amazing Grace” and Bette Midler’s “Wind Beneath My Wings.”

Marine Corps veteran Edward Kiernan read “In Flanders Fields,” a famous war memorial poem written during World War I. Korean War veteran Richard Seybold was honorary bearer of the wreath.

“Every minute, of every hour, of every day, Americans enjoy the blessings of a peace-loving nation — blessings protected by the selfless service of men and women in uniform,” Fred Sganga, executive director of the veterans home, said to the crowd. “The America we know would not be the same were it not for the men and women we honor on Memorial Day … a single day during which we honor the spirit of all those who died in service to our nation, but whom we continue to remember and honor in our hearts.”

Stressing the holiday means much more than a three-day weekend, Sganga recognized the collective shift in thinking when it comes to Memorial Day.

“In recent years,” he said, “a new awareness of the sacrifices our military members are making is emerging, becoming an ingrained part of our American experience.”

U.S. State Sen. Ken LaValle (R-Port Jefferson), who delivered the keynote address, read excerpts from President Ronald Reagan’s (R) 1984 address commemorating the 40th anniversary of D-Day. LaValle prefaced by saying, “Whether you served in the second World War, Korean War, Vietnam War or Gulf War, these words apply to you.”

“President Reagan said, ‘Forty summers have passed since the battle that you fought here … you were young the day you took these cliffs, some of you were hardly more than boys, with the deepest joys of life before you. Yet, you risked everything here. Why? What impelled you to put aside the instinct for self-preservation and risk your lives to take these cliffs? … It was faith and belief; it was loyalty and love. All of you loved liberty, all of you were willing to fight tyranny, and you knew people of your countries were behind you.’”

LaValle ended his address by thanking the veterans in attendance for their service.

“On behalf of the Senate and majority leader John Flanagan (R-East Northport), we really appreciate what you do and we try each and every day to make sure this veterans home is everything that you would want it to be,” LaValle said. “We all say thank you.”

To learn more about the Long Island State Veterans Home, visit www.listateveteranshome.org.

Sen. Kenneth LaValle, wearing hat, sits with Brookhaven National Laboratory beamline scientist Dieter Schneider. Looking on from left, BNL Director Doon Gibbs; vice president for development at Cold Spring Harbor Laboratory, Charles Prizzi; NSLS-II director John Hill; and Stony Brook University associate vice president for Brookhaven affairs, Richard Reeder. Photo from Brookhaven National Laboratory

Thanks to the persistent support of state Sen. Ken LaValle (R-Port Jefferson), Brookhaven National Laboratory secured $15 million from New York State to add a state-of-the-art microscope that could contribute to advances in basic science and medicine.

The national laboratory will purchase a new cryo-electron microscope and will use the funds to create a building attached to its National Synchrotron Light Source II.

“Cryo-electron microscopy is an advanced imaging technology that will significantly accelerate scientists’ understanding of molecular structures and processes generally, including many impacts in understanding disease and in aiding drug discovery,” Doon Gibbs, the laboratory director of BNL, said in an email.

BNL will use the funds to purchase the first of what they hope will be four such new microscopes. The lab is finalizing a bid, which is due by June 30 for funds from the National Institutes of Health for three additional microscopes.

“There is an exponentially increasing demand for the type of bio-structural information that such machines provide, and so we are competing to become an East Coast based national facility to serve this rapidly growing community,” James Misewich, the associate director for energy and photon sciences at BNL said in an email.

Having a suite of microscopes would enable BNL to have a spectrum of capabilities to serve the needs of its scientists and of researchers from around the world who flock to the Upton-based lab to conduct their research.

The new facility will create jobs associated with running the cryo-EM, Misewich said. If BNL wins the NIH proposal to become a national cryo-EM facility, it would also employ additional scientists, engineers, technicians and administrators to run the user program.

Misewich said he hopes scientists at nearby Stony Brook University and Cold Spring Harbor Laboratory will benefit from the opportunity to use a combination of its X-ray and electron microscope probes.

Senior members of the BNL team credit LaValle for helping to secure the funds.

“The $15 million in New York State funding is the culmination of a two-year effort led by the senator to bring a cryo-EM to Brookhaven and jump-start this important effort,” Gibbs said.

LaValle suggested that the funds were well worth the investment.

“It is critically important for government to embrace and support the work of the organizations that make life-altering discoveries and better our lives, health and environment,” LaValle said in an email. “This investment will further establish world-leading prominence in the field of medical research, and position the region for additional major investments by the National Institutes of Health and the U.S. Department of Energy.”

Misewich envisions configuring one of the microscopes to allow for electron tomography, which will generate three-dimensional images of cells.

“The approach will be complementary to the X-ray imaging work we can undertake with the NSLS-II beamlines,” Misewich said.

Gibbs explained that the cryo-EM is complementary to X-ray crystallography, which is the traditional method for determining structures, which scientists already do at BNL.

“Few prescription drugs have been approved by the [Food and Drug Administration] for use in the U.S. in the last 20 years without a crystallographic study of their structure by X-rays,” Gibbs continued.

Misewich expects the new microscope could lead to new methods of detection, diagnosis and treatment for diseases like cancer or for medical challenges like antibiotic resistance.

Combining the technological tools of the new cryo-EM with the insights from the NSLS II and the nine-year-old Center for Functional Nanomaterials will enable researchers to “provide much more rapid bio-structure determination in response to needs like the ability to rapidly characterize a virus,” Misewich said.

LaValle sited this effort as a part of his ongoing commitment to build Long Island’s new high-tech economy.

The combination of BNL, SBU and CSHL “will provide a significant boost to the competitiveness of the biosciences and biotechnology communities across Long Island,” LaValle said.