Stony Brook University

Director of the Heart Rhythm Center at Stony Brook Heart Institute Dr. Eric Rashba is holding the new Watchman FLX device, which provides protection from strokes for people with atrial fibrillation. Photo from Stony Brook Medicine

The butterflies that color backyards are welcome companions for spring and summer. The ones that flutter towards the upper part of people’s chests can be discomforting and disconcerting.

In an effort to spread the word about the most common form of heart arrhythmia amid American Heart Month, the Stony Brook Heart Institute recently held a public discussion of Atrial fibrillation, or A-fib.

Caused by a host of factors, including diabetes, chronic high blood pressure, and advanced age, among others, A-fib can increase the risk of significant long-term health problems, including strokes.

In atrial fibrillation, the heart struggles with mechanical squeezing in the top chamber, or the atrium. Blood doesn’t leave the top part of the heart completely and it can pool and cause clots that break off and cause strokes.

Dr. Eric Rashba, who led the call and is the director of the Heart Rhythm Center at Stony Brook Heart Institute, said in an interview that A-fib is becoming increasingly prevalent.

A-fib “continues to go up rapidly as the population ages,” Rashba said. It occurs in about 10% of the population over 65. “As the population ages, we’ll see more of it.”

The Centers for Disease Control and Prevention estimates that 12.1 million people in the United States will have A-fib over the next decade.

As with many health-related issues, doctors advised residents to try to catch any signs of A-fib early, which improves the likely success of remedies like drugs and surgery.

“We prefer to intervene as early as possible in the course of A-fib,” Dr. Ibraham Almasry, cardiac electrophysiologist at the Stony Brook Heart Institute, said during a call with three other doctors. “The triggers tend to be more discreet and localized and we can target them more effectively.”

Different patients have different levels of awareness of A-fib as it’s occurring.

“Every single patient is different,” said Dr. Roger Ran, cardiac electrophysiologist at the Stony Brook Heart Institute. Some people feel an extra beat and could be “incredibly symptomatic,” while others have fatigue, shortness of breath, chest discomfort, and dizziness.

Still other patients “don’t know they are in it and could be in A-fib all the time.”

Doctors on the call described several monitoring options to test for A-fib.

Dr. Abhijeet Singh, who is also a cardiac electrophysiologist at the Stony Brook Heart Institute, described how the technology to evaluate arrhythmias has improved over the last 20 years.

“People used to wear big devices around their necks,” Singh said on the call, which included about 150 people. “Now, the technology has advanced” and patients can wear comfortable patches for up to 14 days, which record every single heartbeat and allow people to signal when they have symptoms.

Patients can also use an extended holter monitor, which allows doctors to track their heartbeat for up to 30 days, while some patients receive implantable recorders, which doctors insert under the skin during a five-minute procedure. The battery life for those is 4.5 years.

Additionally, some phones have apps that record heartbeats that patients can send by email, Singh said. “We have come a long way in a few years.”

Dr. Roger Fan, a cardiac electrophysiologist at the Stony Brook Heart Institute, added that all these technologies mean that “we are virtually guaranteed to get to the bottom” of any symptoms.

Drugs vs. surgery

Doctors offer patients with confirmed cases of A-fib two primary treatment options: drugs or surgery.

The surgical procedure is called an ablation and involves entering the body through veins in the groin and freezing or burning small areas that are interfering with the heart’s normal rhythm. The procedure breaks up the electrical signals in irregular heartbeats.

Performed under general anesthetic, the procedure generally takes two to three hours. Patients can return home the same day as the operation, Rashba said.

As with any surgery, an ablation has some risks, such as stroke or heart attack, which Rashba said are “very rare” and occur in fewer than one percent of the cases. Additionally, patients may have groin complications, although that, too, has declined as doctors have used ultrasound to visualize the blood vessels.

In extremely rare occasions, some patients also have damage to the esophagus behind the heart, said Rashba, who is also a professor of medicine.

For patients experiencing symptoms like A-fib, doctors recommended a trip to the emergency room, at least the first time.

“If it’s not going away, one, you can reassure yourself, two, you can get treatment, and three, you can get a diagnosis quickly,” said Almasry.

The Stony Brook doctors said choosing the best treatment option depends on the patient.

“Everybody has different manifestations of their A-fib,” said Fan.

Among other questions, doctors consider how dangerous the A-fib is for the patients, how severe the symptoms are, and how much they affect the quality of life.

Doctors urged residents to make the kind of healthy lifestyle choices that keep other systems functioning effectively. Almasry cited a direct correlation between obesity and A-fib.

Reducing body weight by 10%, while keeping the weight off, can reduce the likelihood of A-fib recurrence, he said.

Photo courtesy of SBU Athletics

Defend the Island is a motto that the Stony Brook University men’s lacrosse team preaches, and the Seawolves lived up to that mantra last weekend as they successfully captured the first-ever Long Island Cup with a 10-6 victory over LIU. Stony Brook used a gritty defensive effort to limit the Sharks to just six goals en route to picking up its fourth-straight win on Feb. 27.

The Seawolves improved to 4-0 on the young season and are off to their best start since they began the 2017 season with the same 4-0 record. The six goals allowed are the fewest in a game since they held Hartford to six goals on April 3, 2021.

Stony Brook took a commanding 4-0 lead in the first quarter and was fueled by early goals from senior midfielder Matt Anderson, sophomore attack Dylan Pallonetti, and sophomore attack Noah Armitage. Pallonetti scored a pair of goals in the opening frame as the Seawolves took the four-goal advantage into the second quarter. 

The teams traded goals in the third quarter and Stony Brook took a 5-1 lead into the halftime break. The Seawolves’ early advantage was too much for the Sharks to overcome as Stony Brook held on to win by the final score of 10-6.

 Stony Brook’s defense held the Sharks’ top two goal scorers in check. LIU’s leading scorer Blake Behlen was limited to two goals and its second-leading scorer entering the game Jake Gillis was held scoreless. Seawolves’ senior goalie Anthony Palma stood on his head as he made 11 saves and only allowed the six goals.

 The Seawolves’ offense was led by Pallonetti who recorded a game-high five points (two goals, three assists). Armitage recorded his second hat trick of the season, while Anderson and graduate midfield Mike McCannell each scored a pair of goals.

“It’s exciting. The guys came out and competed in a great event against a good team. I am really excited about our effort – that’s the best defense that we played in probably three years that we have been here at Stony Brook. I couldn’t be prouder of those guys flying around out there,” said head coach Anthony Gilardi.

Next up, the team returns to LaValle Stadium to host Rutgers on March 5 at noon.

Photo courtesy of SBU Athletics

Starting the day with the first six goals, the Stony Brook women’s lacrosse team quickly made its presence felt on Feb. 27 against Ivy League foe Dartmouth.

Siobhan Rafferty had a first-quarter hat trick as part of her five-goal day, and the No. 4 Seawolves were off and running en route to their 20-3 victory in front of 1,040 fans at Kenneth P. LaValle Stadium.

Rafferty and Kailyn Hart went back to back inside of 20 seconds to get the offense up and running, and then three goals in a 90 second span, two from Rafferty, made it 6-0 in the first quarter. After Dartmouth got one back a woman up, the Seawolves rattled off five in a row, three of which coming from Hart, to go up 11-1 at the 10:48 mark of the second quarter. Hart also finished the day with a five-spot in the goal column.

Stony Brook pitched a second-half shutout, scoring all eight in the final 30 minutes of action. Molly LaForge and Alexandra Fusco each recorded their first collegiate tallies, with Fusco scoring both in the final frame for the Seawolves. With the win, the Seawolves find a groove ahead of a pair of Top 10 matchups ahead in the next two weeks.

An overhead view of flooding at the Ranomafana area in Madagascar, above. Photo by Dina Andrianoely

Stony Brook University distinguished professor and award-winning scientist Patricia Wright has been traveling back and forth to Madagascar for over 34 years to study the charismatic lemurs on the island nation off the southeastern coast of Africa.

A damage to a road in Madagascar. Photo by Dina Andrianoely

Recently, Wright was in Madagascar when Tropical Cyclone Emnati struck the nation, tearing roofs from homes, destroying crops and polluting drinking water.

“The actual howling of the wind was very eerie,” said Wright in an interview a few days after returning from Madagascar. “The river is right beneath the station and it was scary to watch it go from white water rapids, into roiling coffee-colored water. Every 15 minutes, you could notice a difference” in the flooded waters.

Wright, her daughter Amanda Wright Poston, who is a project manager with the Woodwell Climate Research Center, and PhD candidate Amanda Rowe are seeking donations through WISE Tropics.

Created in 2020, WISE Tropics, which stands for Wright’s Institute for Science & Environment, has numerous goals, including saving lemurs, planting new rainforests and helping people in Madagascar and other tropical countries that have high biodiversity and high poverty.

In response to Tropical Cyclone Emnati, which is the fourth cyclone to hit Madagascar this year, WISE Tropics is trying to raise $20,000 from donors to provide food for people whose crops were destroyed by
the storm.

“People are displaced from their homes and they are really hungry,” Wright said. “The crops are gone: they are washed away.”

Wright said she hoped to buy as many as 100 bags of 50 kilograms of rice, plus beans, sugar and salt that could support communities around Ranomofana National Park, which provides the nearby setting for research through Stony Brook’s Centre ValBio.

She hopes to raise enough money that she can provide additional food every two weeks for the next two months.

A week after Emnati, residents of Madagascar were also struggling with contaminated drinking water, which was causing diarrhea. 

Wright said she hasn’t seen this level of devastation to Madagascar in about a decade.

An overhead view of flooding at the Ranomafana area in Madagascar, above. Photo by Dina Andrianoely

She hopes Long Islanders support those struggling after a spate of storms disrupted their lives and threatened their futures.

“Long Islanders are very generous when it comes to donating for disasters,” Wright said. “We had Sandy ourselves. We can make this island to island connection.”

Wildlife on Madagascar, like endangered lemurs, are often able to survive during natural disasters.

Lemurs move close to the center of trees and lower down to avoid the strong winds, Wright described. While she has seen lemurs who died amid storms, many survive by finding natural protection.

Wright recognizes that the number of crisis points in the world has grown, with refugees and survivors leaving their homes in Ukraine amid Russia’s armed attack and amid flooding in parts of Australia.

One of the lessons she’s learned from working with people in Madagascar amid past disasters is that donations sometimes meet the immediate need but don’t always provide enough sustained support.

Origins of WISE

Amanda Poston said they established WISE Tropics to give donors who wanted to give 100% of their gifts directly to specific efforts.

“We created this so we could really have them participate in these on-the-ground projects,” Poston said.

Before the cyclones hit, donors had contributed to reforestation efforts and lemur research, which is at the heart of what Patricia Wright studies.

“People who are interested in Ranomofana and have a connection to Madagascar are able to help” through these donations, Poston said.

WISE Tropics has almost no overhead, which means that donations go directly to the intended recipients.

At this point, the need to help the Malagasy people get food and shelter is high, as the island nation recovers from storms that have closed off roads and demolished bridges.

Poston, who spent a good part of her childhood in Madagascar, said the Malagasy “respect [her mother] and are amazed at her continuous contributions to their country.”

Esther Takeuchi

Esther S. Takeuchi, PhD, Distinguished Professor and the William and Jane Knapp Chair at Stony Brook University is being honored by the National Academy of Sciences (NAS) and will receive the Award in Chemical Sciences. This award is in recognition of her breakthrough contributions in the understanding of electrochemical energy storage.  

Takeuchi, who holds a joint appointment at Department of Energy’s (DOE) Brookhaven National Laboratory, is an internationally recognized inventor, researcher, and educator in the fields of materials science, chemistry and renewable energy. She will be honored in a ceremony during the NAS 159th annual meeting on May 1 and will receive a medal and prize of $15,000 sponsored by the Merck Company Foundation.

The award cites Takeuchi’s contributions “to the materials and mechanistic understanding relevant to electrochemical energy storage, using chemical insight to address issues of critical importance.”

“I am sincerely honored to receive the National Academy of Science Award for Chemical Sciences,” said Takeuchi, also the Knapp Chair Professor of Energy and the Environment in the Department of Materials Science and Chemical Engineering “The fundamental chemistry of electrochemical energy storage is complex and the subsequent development of viable energy storage devices is made even more challenging by the unique demands of each application.”

Takeuchi’s research has been instrumental in energy storage improvements that meet societal needs and can be applied to electric vehicles, medical devices, and batteries that back up the power grid. Among her numerous and notable inventions is a compact lithium/silver vanadium oxide battery that increased the lifespan of implantable cardiac defibrillators, a solution that reduced the number of surgeries patients needed to undergo to replace the devices that detect and correct irregular, potentially fatal, heart rhythms.

Takeuchi was recently elected a member of the American Academy of Arts and Sciences. She has also been inducted into the National Academy of Engineering and selected as a Fellow of the American Institute for Medical and Biological Engineering and the American Association for the Advancement of Science. She was selected as the 2013 recipient of the E.V. Murphree Award in Industrial and Engineering Chemistry from the American Chemical Society. She was inducted into the National Inventors Hall of Fame in 2011. In 2009, President Obama presented Takeuchi with the National Medal of Technology and Innovation, the highest honor possible for technological achievement in the United States.

#51 Matt Anderson and #4 Kevin Mack celebrate their team's victory during Sunday's game. Photo from Stony Brook Athletics

The Stony Brook University men’s lacrosse team (2-0) used a second half surge to power past Robert Morris University Colonials (0-3), 18-14, to pick up its second consecutive win on Feb. 19. The 18 goals were the most that the Seawolves scored in a game since it found the back of the net 22 times in a win over Binghamton on April 16, 2021.

Stony Brook was paced by 10 different goal scorers and standout play from senior goalie Anthony Palma who made a career-high 17 saves en route to the victory. Sophomore attack Noah Armitage, sophomore attack Dylan Pallonetti, and graduate midfield Mike McCannell each finished the game with a hat trick.

Five Seawolves recorded multi-goal performances and six finished with multi-point games. Pallonetti (three goals, three assists) and graduate attack Kevin Mack (two goals, four assists) tied for the game-high with six points apiece. Junior face-off specialist Renz Conlon set the tone on offense as he won 20-of-34 face-offs and started the game 6-of-7.

Stony Brook jumped out to an early 7-0 lead in the first quarter as senior midfield Matt Anderson led the attack with a pair of goals out of the gate. Robert Morris mounted a comeback and went on a 9-2 run and the teams were tied up at 9-9 after the first half of play.

The Seawolves pulled away from the Colonials in the third quarter as they outscored them, 6-1, in the frame to take a 15-10 advantage into the fourth quarter. Stony Brook sealed the game in the fourth quarter as it received goals from McCannell, graduate midfield Wayne White, and Pallonetti to ice the game.

“I thought it was a battle. We knew going in that this was going to be a physical, up and down, high-scoring game — and it was. I am proud of the guys for finding a way to win. There were some mental mistakes that I think being two games in its something that we need to continue to work through, but the guys battled and that’s what we were hoping for,” said head coach Anthony Gilardi.

#15 Anthony Roberts takes a shot at last Sunday's game. Photo from Stony Brook Athletics

In a scoring performance not seen since Jameel Warney’s 2016 America East Championship output, Anthony Roberts lit up the scoreboard to help the Seawolves to a second consecutive win on Feb. 13 in Bangor, Maine.

He hit nine 3-pointers, the most by any player in Seawolves program history, as Stony Brook cruised to an 85-74 victory at the Cross Insurance Center. He finished the day with 40 points, the seventh time that milestone has been hit by a men’s basketball player.

A 10-3 run in the first half help the Seawolves seize the lead, with Tykei Greene chipping in half during that stretch. Maine would pull ahead as much as four in that stanza at 26-22, but the Seawolves responded again with a 13-3 run, during which 11 of the points came from Roberts, to take the lead for good.

The Seawolves were able to gradually extend their lead as large as 16 in the second half, keeping Maine at bay with the lead being double figures for the majority of the final ten minutes.

“It was a big road win for us. I’m really proud of our guys for rallying shorthanded and with all of the stuff they’ve been forced to deal with. It has been a very difficult couple of weeks for us. Tykei was able to play a really nice game for us and Anthony Roberts played at an extremely high level,” said head coach Geno Ford.

The team headed from the northern-most league opponent to the southern-most, heading to UMBC on Wednesday night in Baltimore, Md. Results were not available as of press time.

Head coach Ashley Langford celebrates her team's victory during last Monday's game. Photo from Stony Brook Athletics

The Stony Brook women’s basketball team bounced back after a tough loss to Maine to defeat UMBC, 64-48, on Feb. 14 in Baltimore, Md. The Seawolves improve to 21-3, 12-2 America East on the season.

Graduate forward Leighah-Amori Wool lit up the scoreboard for Stony Brook leading all scorers with a season-high 23 points. Wool is the latest player to knock down 20+ points since graduate forward India Pagan finished with 21 against Binghamton on Jan. 19.

Senior guard Anastasia Warren and Pagan followed behind Wool also finishing in double-figures on the night. Pagan finished with 14 points and added 10 rebounds to secure her fifth career double-double and second on the season. Warren filled the stat sheet for the Seawolves chipping in 12 points and grabbing a season-high nine rebounds.

 Stony Brook came out strong with an early lead, but the Retrievers would eventually take a 28-22 lead off a 9-0 scoring run in the second quarter. The Seawolves were able to gain momentum in the second half and come out on top after a layup from Wool to 9:38 to go in the third quarter. Stony Brook would not trail for the remainder of the contest.

The team was back in action Feb. 16 when they took on UMBC back home at The Island. Results were not available as of press time. 

A paper published this week in Immunity, a leading research journal highlighting discoveries in immunology by Cell Press, lays the groundwork to better understand and treat Crohn’s disease, a type of Inflammatory Bowel Disease (IBD). Beneficial interactions among intestinal cell types limit the harmful effects of a dysregulated gut microbiota, which is comprised of trillions of bacteria, viruses, and other microorganisms. These cell-cell interactions are essential to maintain a healthy gut and dysregulation of this cellular “crosstalk” can predispose the development of IBD.

Pawan Kumar

Led by Pawan Kumar, BVSc, PhD, of the Renaissance School of Medicine at Stony Brook University, the research identified a new role for Interleukin-17A (IL-17A), an immune cell-derived cytokine, in promoting selective epithelial cell development as well as limiting inflammation during colitis.Although drugs that target IL-17A are highly effective against psoriasis, an autoimmune condition, the same drugs result in adverse effects when used to treat the inflammatory responses of Crohn’s. While targeting IL-17A may reduce the pathogenesis of certain inflammatory responses, it is unclear why these treatments had opposing effects in Crohn’s patients. The research team has addressed this underlying question.

“We identified a new role for IL-17A in the intestinal inflammatory process by regulating a type of stem cell (Lgr5+) and progenitor cell function,” said Kumar, Senior Author and an Assistant Professor in the Department of Microbiology and Immunology. “We found that IL-17A acts on intestinal stem cells to promote secretory cell lineage commitment. In addition, impaired IL-17A signaling to secretory cells (ATOH1+) exacerbates colitis.

The research team tested their findings in different murine models. Upon collaborating with Ken Cadwell of New York University, they confirmed their results in human organoids. They found that IL-17A stimulated secretory cell differentiation in cystic human intestinal organoids.“Our data suggest that there is a ‘cross talk’ between immune cells and stem cells that regulates secretory cell lineage commitment and the integrity of the mucosa,” summarizes Kumar.

The authors believe their findings will help further research and lay the groundwork for future clinical studies that investigate the therapeutic potential of IL-17A and/or its downstream effector proteins.This research is supported in part by the National Institute of Diabetes and Digestive and Kidney Diseases, the Crohn’s and Colitis Foundation, the SUNY Research Foundation and a National Science Foundation Graduate Research Fellowship.

Photo from Stony Brook Athletics

The Stony Brook University men’s track and field team competed in the Bruce Lehane Scarlet and White Invitational on Feb. 5 at Boston University.

Coach Andy Ronan with Robert Becker.
Photo from Stony Brook Athletics

Senior Robert Becker has been breaking records ever since he got to Stony Brook. He took it to the next level by becoming the first student-athlete to run a sub-4-minute mile in program history. Becker clocked in at 3:58.98 in the mile run setting a new personal best and breaking the previous mile record (4:02.45) that was also set by himself in 2020 at the ECAC/IC4A Indoor Championships. Becker’s record-breaking time also qualifies the senior for the IC4A Championships.

“Robert Becker made history today at the Bruce Lehane Scarlet and White Invitational by becoming the first Stony Brook student-athlete to break the 4-minute mile. Rob ran 3:58.98 to achieve this great moment in his career. It is truly a landmark performance, one that many chase but never attain – Rob has joined an exclusive club. There were many super performances today, career bests, and IC4A/ECAC qualifiers were the nature of the day,” said head coach Andrew Ronan. 

“Considering the news that we received earlier this week about being ineligible for the conference championships, we had a great meet. This group of athletes pulled themselves together, got focused, and showed the kind of quality performances that could have been on display at the conference championship meet,” he added.

The Seawolves are back in action on Feb. 11 when they compete in the Fast Track National Invite on Staten Island.