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About 70% of people with Parkinson’s experience a tremor at some point in the disease. Stock photo
Much new research focuses on dietary approaches

By David Dunaief

Dr. David Dunaief

Parkinson’s disease is a neurodegenerative disease, most often associated with a movement disorder, or tremors. According to the Parkinson’s Foundation, roughly 60,000 Americans are diagnosed with Parkinson’s disease (PD) each year, and approximately one million Americans are living with PD (1).

Patients with PD suffer from a collection of symptoms caused by the breakdown of brain neurons. In medicine, we know the most common symptoms by the mnemonic TRAP: tremors while resting, rigidity, akinesia/bradykinesia (inability/difficulty to move or slow movements) and postural instability or balance issues. It can also result in a masked face, one that has become expressionless, and potentially dementia.

There are several different subtypes of PD; the diffuse/malignant phenotype has the highest propensity toward cognitive decline (2).

There’s a lot we still don’t know about the causes of PD; however, risk factors may include head trauma, reduced vitamin D, milk intake, well water, being overweight, high levels of dietary iron, and migraine with aura in middle age.

The part of the brain most affected is the basal ganglia, and the prime culprit is dopamine deficiency that occurs in this brain region (3). Adding back dopamine has been the mainstay of medical treatment, but eventually the neurons themselves break down, and the medication becomes less effective. Is there hope? Yes, in the form of medications and deep brain stimulatory surgery, but also with lifestyle modifications. Lifestyle factors include iron, vitamin D and CoQ10. The research, unfortunately, is not conclusive, though it is intriguing.

Reducing iron in the brain

This heavy metal is potentially harmful for neurodegenerative diseases such as Alzheimer’s disease, macular degeneration, multiple sclerosis and, yes, Parkinson’s disease. The problem is that this heavy metal can cause oxidative damage.

In a small, yet well-designed, randomized controlled trial (RCT), researchers used a chelator to remove iron from the substantia nigra, a specific part of the brain where iron breakdown may be dysfunctional. An iron chelator is a drug that removes the iron. Here, deferiprone (DFP) was used at a modest dose of 30 mg/kg/d (4). This drug was mostly well-tolerated.

The chelator reduced the risk of disease progression significantly on the Unified Parkinson Disease Rating Scale (UPDRS) during the 12-month study. Participants who were treated sooner had lower levels of iron compared to a group that used the chelator six months later. A specialized MRI was used to measure levels of iron in the brain.

The iron chelator does not affect, nor should it affect, systemic levels of iron, only those in the brain specifically focused on the substantia nigra region. The chelator may work by preventing degradation of the dopamine-containing neurons. It also may be recommended to consume foods that contain less iron.

Does CoQ10 slow progression?

When we typically think of using CoQ10, a coenzyme found in over-the-counter supplements, it is to compensate for depletion from statin drugs or due to heart failure. Typical doses range from 100 to 300 mg. However, there is evidence that CoQ10 may be beneficial in Parkinson’s at much higher doses.

In an RCT, results showed that those given 1,200 mg of CoQ10 daily reduced the progression of the disease significantly based on UPDRS changes, compared to the placebo group (5). Other doses of 300 and 600 mg showed trends toward benefit, but were not significant. This was a 16-month trial in a small population of 80 patients. Unfortunately, results for other CoQ10 studies have been mixed. In this study, CoQ10 was well-tolerated at even the highest dose. Thus, there may be no downside to trying CoQ10 in those with PD.

Is Vitamin D part of the puzzle?

In a prospective study, results show that vitamin D levels measured in the highest quartile reduced the risk of developing Parkinson’s disease by 65 percent, compared to the lowest quartile (6). This is quite impressive, especially since the highest quartile patients had vitamin D levels that were what we would qualify as insufficient, with blood levels of 20 ng/ml, while those in the lowest quartile had deficient blood levels of 10 ng/ml or less. There were over 3,000 patients involved in this study with an age range of 50 to 79.

While many times we are deficient in vitamin D and have a disease, replacing the vitamin does nothing to help the disease. Here, it does. Vitamin D may play dual roles of both reducing the risk of Parkinson’s disease and slowing its progression.

In an RCT, results showed that 1,200 IU of vitamin D taken daily may have reduced the progression of Parkinson’s disease significantly on the UPDRS compared to a placebo over a 12-month duration (7). Also, this amount of vitamin D increased the blood levels by almost two times from 22.5 to 41.7 ng/ml. There were 121 patients involved in this study with a mean age of 72.

So, what have we learned? Though medication with dopamine agonists is the gold standard for the treatment of Parkinson’s disease, lifestyle modifications can have a significant impact on both prevention and treatment of this disease. Each lifestyle change in isolation may have modest effects, but cumulatively their impact could be significant. The most exciting part is that lifestyle modifications have the potential to slow the disease progression and thus have a protective effect.

References:

(1) parkinson.org. (2) JAMA Neurol. 2015;72:863-873. (3) uptodate.com. (4) Antioxid Redox Signal. 2014;10;21(2):195-210. (5) Arch Neurol. 2002;59(10):1541-1550. (6) Arch Neurol. 2010;67(7):808-811. (7) Am J Clin Nutr. 2013;97(5):1004-1013.

Dr. David Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com. 

Attendees at a conference at CSHL, an in-person tradition started in 1933. These conferences were suspended from 1943 to 1945 during WWII and were virtual during the pandemic in 2020 and for most of 2021. Photo by Miriam Chuai/CSHL

By Daniel Dunaief

For scientists, meetings and conferences aren’t just a chance to catch up on the latest research, gossip and see old friends: they can also provide an intellectual spark that enhances their careers and leads to new collaborations.

Amid the pandemic, almost all of those in-person conferences stopped, including the annual courses and meetings that Cold Spring Harbor Laboratory hosts. The internationally renowned lab has run meetings since 1933, with a few years off between 1943 and 1945 during World War II.

CSHL’s David Stewart. Photo by Gina Motisi/CSHL

While scientists made progress on everything from basic to translational research, including in laboratories that pivoted towards work on the SARS-CoV-2 virus, which causes COVID-19, they missed out on the kinds of opportunities that come from in-person interactions.

Assuming COVID infection rates are low enough this fall, CSHL is hoping to restart in-person conferences and courses, with the first conference that will address fifty years of the enzyme reverse transcriptase scheduled for Oct. 20th through the 23rd. That event was originally scheduled for October of 2020.

One of the planned guest speakers for that conference, David Baltimore, who discovered the enzyme that enables RNA to transfer information to DNA and is involved in retroviruses like HIV, won the Nobel Prize.

“I am hoping that there will be significant participation by many eminent scientists, so that is in itself somewhat [of] a ceremonial start,” wrote David Stewart, Executive Director of meetings and courses at Cold Spring Harbor Laboratory.

To attend any of the seven in-person meetings on the calendar before the end of the year, participants need to have vaccinations from either Pfizer, Moderna, Johnson & Johnson or AstraZeneca.

Attendees will have to complete an online form and bring a vaccination card or certificate. Scientists who don’t provide that information “will not be admitted and will not get a key to their room or be able to attend the event,” Stewart said.

CSHL also plans to maintain the thorough and deep cleaning procedures the lab developed. 

Stewart hopes that 75 to 80 percent or more of the talks presented will be live, with a virtual audience that could be larger than the in-person attendance.

“It is important to have a critical mass of presenters and audience in-person, but there’s no real limit on how large the virtual audience could be,” he explained.

Typically, the courses attract participants from over 50 countries. Even this year, especially with travel restrictions for some countries still in place, Stewart expects that the majority of participants will travel from locations within the United States.

The Executive Director explained that CSHL was planning to introduce a carbon offset program for all travel to conferences and courses that the facility reimburses starting in 2020. After evaluating several options, they plan to purchase carbon offsets from Cool Effect and will encourage participants paying their own way to do the same or through a similar program.

The courses, meanwhile, will begin on October 4th, with macromolecular crystallography and programming for biology. CSHL hopes to run six of these courses before the end of the year, including a scientific writing retreat.

“We are looking to 100 percent enrollment for our courses, so likely this year that will largely be domestic,” Stewart explained.

The courses, which normally have 16 participants, may have 12 students, as the lab tries to run these training opportunities safely without masks or social distancing.

From March of 2020 through the end of last year, the lab had planned 25 meetings and 25 courses. As the pandemic spread, the lab pivoted to virtual meetings. “I felt like a car salesman trying to sell virtual conferences,” Stewart recalled. For the most part, the lab was able to keep to its original schedule of conferences, albeit through a virtual format.

In addition to the scheduled meetings, CSHL decided to add meetings to discuss the latest scientific information related to COVID research. 

Stewart approached Hung Fan, a retired virologist at the University of California at Irvine, to help put together these COVID exchanges. Those meetings occurred in June, July, August, October, and January. The sixth one recently concluded.

The meetings addressed “everything around the science of the virus,” Stewart said, which included the biology, the origin, the genomics, the immune response, vaccines, therapeutics and diagnostics, among other scientific issues.

“There was a lot of excellent work being done around SARS-CoV-2,” Stewart said. “We were trying to identify that early on. It was helpful to have people who knew the field well.”

Fan said he combed through preprints like the CSHL-based bioRxiv and related medRxiv every day for important updates on the disease.

Fan described the scientific focus and effort of the research community as being akin to the Manhattan Project which built the atomic bomb during World War II, where “everybody said, ‘We have a common enemy and we want to apply all our capabilities to combating that.”

While Fan is pleased with the productive and valuable exchanges that occurred amid the virtual conferences, he recognized the benefit of sharing a room and a drink with scientific colleagues.

“A lot of the productive interactions at meetings take place in a social setting, at the bar, over dinner” and in other unstructured gatherings, he said. “People are relaxed and can share their scientific thoughts.”

After presentations, Fan described how researchers discuss the work presented and compare that to their own efforts. It’s easier to talk with people in person “as opposed to making a formalized approach through letters and emails.”

Blueberry-Pecan Bread. Photo from Unsplash

By Barbara Beltrami

Blueberries! Blueberry pie, blueberry fool, blueberry buckle, blueberry crisp, blueberry crumble, blueberry muffins, blueberry pancakes, blueberry tarts and cakes, smoothies, coolers, and just plain blueberries that leave stains on your teeth and fingers. What recipes shall I choose? I can’t decide! So I’m going to share with you some spin-offs on a few of them and hope you like them as much as the traditional ones.

Blueberry-Pecan Bread

YIELD: Makes one loaf

INGREDIENTS:

2 cups flour

1/4 teaspoon salt

1 tablespoon baking powder

1 cup sugar

1 cup blueberries

1/2 cup chopped pecans

2 eggs well-beaten

1 cup milk

3 tablespoons vegetable oil

DIRECTIONS:

Preheat oven to 350 F. Line a 9 x 5 x 3” loaf pan with waxed paper. In a large bowl, sift together the flour, salt, baking powder and sugar; add berries and nuts and stir to combine. In a medium bowl, whisk together the eggs, milk and oil; add to dry mixture and stir just enough to moisten; pour into prepared loaf pan and let sit about 20 minutes. Bake one hour or until cake tester inserted in center comes out clean.  Serve with iced coffee or iced tea.

Blueberry Skillet Pancake

YIELD: Makes 4 servings

INGREDIENTS:

1 cup flour

1 tablespoon + 1 teaspoon sugar

1 1/2 teaspoons baking powder

1/2 teaspoon kosher salt

3/4 cup half and half

1 large egg at room temperature

3 tablespoons unsalted butter, melted

1/2 pint blueberries

Confectioners sugar

DIRECTIONS:

Place oven rack in upper third of oven; preheat oven to 375 F. Place 10” cast iron skillet in oven. In large bowl combine flour, 3 tablespoons of the sugar, the baking powder and salt. In a medium bowl whisk together the half and half, egg and two tablespoons of the butter. Stir wet mixture into dry mixture until just moistened. With a potholder carefully remove skillet from oven; swirl remaining tablespoon of butter to coat bottom and sides of pan; pour batter in pan and smooth top; sprinkle evenly with blueberries and remaining teaspoon sugar. Bake 20 to 30 minutes until cooked through and golden on top; sprinkle with confectioners’ sugar. Serve with blueberry syrup, fresh blueberries and whipped cream.

Blueberry Custard Tart

YIELD: Makes 6 to 8 servings

INGREDIENTS:

4 large eggs, well beaten

2/3 cup sugar

1/2 teaspoon salt

1/2 teaspoon nutmeg

2 2/3 cups milk

1 teaspoon vanilla extract

1 unbaked 9” pie shell

1 cup blueberries

2 tablespoons orange juice

3 tablespoons confectioners’ sugar

DIRECTIONS:

Preheat oven to 425 F. In a medium bowl combine eggs, sugar, salt, milk, nutmeg and vanilla; stir until smooth; pour mixture into pie shell and bake 15 minutes, then reduce temperature to 350 F and bake 30 minutes more, until knife inserted about one inch from edge of pastry shell comes out clean. Remove from oven and let cool; refrigerate if not serving immediately. In a medium bowl toss the blueberries, orange juice and confectioners’ sugar; spoon over cream filling just before serving. 

Stock photo

By Nancy Marr

Americans have become aware that our system of family care is disjointed and sometimes inaccessible. The pandemic particularly highlighted the problem of childcare, as essential workers had to leave their jobs because their child care resources had closed. The American Rescue Plan (ARP), passed by Congress in 2021, helped day care centers, home and family childcare providers stay open or reopen and provide protective and sanitizing equipment.  

The League of Women Voters of the United States since 1988 has supported programs at all levels of government to expand the supply of affordable, quality childcare for all who need it. The League also participates in the Pre-K Coalition in New York State, advocating for investing in children’s early years to lay the foundation for reading, writing, and math skills. Many Pre-K programs are funded through school districts, open free to parents through a lottery, but frequently for only half a day. 

The Coalition on Human Needs (www.chn.org, July 19) reported that, even before the pandemic, childcare was unaffordable for many families. In many parts of the country, families pay more than $10,000 a year per child for child care. That’s 16% of the median household income, but far more for many families.

New York State has just announced that it will use the funding of $25 million it has received from the federal government for child care scholarships for essential workers, whose income is less than $79,500 for a family of four. Additional federal funding of $105 million granted to New York State in 2021 will be used to expand Pre-K programs; on Long Island, $31.9 million dollars will make it possible to seat 5,200 four year olds, mostly for full-day care. 

This July, through the Child Tax Credit program (which has existed since the 1990’s), parents with joint incomes of $150,000, head of household filers with incomes of $112,500 and single filers with incomes of $75,000 have received the first monthly payment of $300 for each child younger than 6, and $250 for each child between 6 and 17. Parents with incomes up to $170,000 will receive payments but they will be less. The American Rescue Act recently increased the amount of credit and made it possible for families to receive payment each month, beginning in July 2021 with the remaining funds granted at the end of the year with the tax filing.   

Separately, the Earned Income Tax Credit, or the EITC, is a refundable tax credit for low-wage workers that was expanded through the American Rescue Act. For taxable year 2020, parents “earned” between $1,502 to $6,728 depending on their tax-filing status, and the income they earned that year.

President Biden has proposed the American Families Plan and hopes to have it passed. His proposal would pay for universal Pre-K and free community college, an investment in child care of $225 billion over 10 years to federally supported child care providers and $200 billion for free pre-school programs for 3 and 4 year olds, and a cap on child care costs at 7 percent of a family’s earnings. 

The proposal also calls for a national paid family and medical leave. Should ARP not be refunded, the benefit amounts of the child tax credit and the Earned Income Credit will go back to their original amounts. To support the enhanced amounts and monthly distribution, contact your Congressperson. Also write to support the efforts of New York State Senator Todd Kaminsky (D Long Beach) for his support of child care funding.

Nancy Marr is vice-president of the League of Women Voters of Suffolk County, a nonprofit, nonpartisan organization that encourages the informed and active participation of citizens in government and influences public policy through education and advocacy. For more information, visit www.lwv-suffolkcounty.org, email [email protected] or call 631-862-6860.

Pixabay photo

We thought that the end was near with the coronavirus, but unfortunately the new Delta variant has people across the country concerned. 

While many people — 68% of New Yorkers ages 18 and older — have been fully vaccinated, Gov. Andrew Cuomo (D) said this week that 21 Long Island zip codes have low vaccination rates. The state will spend $15 million to target these communities in an effort to get more people vaccinated. 

During his press conference on Monday, Cuomo said that new daily cases have been jumping due to the highly contagious Delta variant of the virus. 

Cuomo added that about 75% of adults in the state have received at least one dose of the vaccine, but 25% have not — which is a total of 3.5 million people. Only 0.15% of people in the state who are vaccinated have become infected with the virus.

While things have opened up again, and life seems to be back to normal, the Delta variant can change that quickly. In areas that Cuomo named, which included parts of Rocky Point, Miller Place, Selden, Port Jefferson Station and Lake Grove, the $15 million funding from the state budget will be used to strengthen communication, expand public education and enhance ongoing outreach efforts throughout diverse communities.

But that isn’t enough. 

The fact that so many people are choosing not to get vaccinated, and who are not being careful in doing so, is concerning. We understand that there are people who have extreme health issues that prevent them from getting the jab, and we respect that. We understand that everyone has the right to choose to be vaccinated, but when there is a public health crisis that has taken the lives of so many innocent people, how could one not choose to get the shot? 

There is a lot of false information out there, and it’s sad to see that no one trusts science anymore. What happened to March 2020 when everyone was in this together? Why did something like a shot to prevent getting sick become so polarizing? Why are people fighting in supermarkets if they choose to wear a mask for protection, and someone who is anti-mask disagrees? 

Of all the new and recent COVID-19 cases statewide, 72% come from the Delta variant. Don’t we want to get back to normal? Weddings are finally allowed to include more than 50 people. Meetings are in-person again. We have a lot to look forward to, and it would be so disappointing to fall back to where we were last year because of fear or misinformation. 

Protect yourself. Protect your friends and family. This can be prevented.

Kitten season is in full swing and the Smithtown Animal Shelter has several kittens available ranging from 10 to 16 weeks old. All kittens adopted from the shelter are spayed/neutered, parasite tested, microchipped, tested for Feline Leukemia and FIV and started on their kitten vaccine series. 

If you are interested in meeting a kitten, please call ahead to schedule an hour to properly interact with him or her in a domestic setting, which includes a Meet and Greet Room.  

The Smithtown Animal & Adoption Shelter is located at 410 Middle Country Road, Smithtown. Shelter operating hours are currently Monday to Saturday from 10 a.m. to 3 p.m. (Sundays and Wednesday evenings by appointment only). For more information, call 631-360-7575 or visit www.smithtownanimalshelter.com.

Stock photo

By Elof Axel Carlson

Elof Axel Carlson

The IQ or intelligence quotient was introduced early in the 20th century to measure learning abilities in school children. It spread from Germany to the United States where it was enthusiastically adopted in K-12 schools.  

I took the test four times. The first score I got, 116, was in first or second grade. The second score, about 3 years later, was 130. The third test in junior high school (PS210) was 149. The last score was in my freshman orientation week at NYU and it was 160. How do I know my scores? I was a teacher’s pet throughout my education and in high school, one of my volunteer activities was filing the report cards of students after teacher’s made their entries. 

In the process of filing I looked at my own record card (and my friends) and saw my scores for K-12. I saw my NYU score while being counseled in the Freshman week follow up. My test scores for various aptitude tests were on the sheet of paper my counselor was reading. She said I was talented but very insecure.  

The IQ score is usually interpreted in 30-point intervals with normal 100 (86-115); bright 130 (116- 145); and genius (146 and up) for the more intelligent students. 

A more damning score exists for categories of students classified as slow learners, with a terminology no longer used, morons 70 ( 56-85); imbeciles 40 (26-55); and idiots (25 and below). Those with less than normal IQ scores are sometimes classified collectively as retarded, feebleminded, or regarded or euphemistically as exceptional children.  

High IQ was widely admired and accepted as the basis for success in  school and in life. Lewis Terman’s Genetic Studies of Genius used the IQ test about 1910 to identify 1000 gifted children in California (mean IQ = 140). They were followed at Stanford University for more than 50 years.  They became college educated successful lawyers, MDs, professors, CEOs and other middle-class professionals with numerous publications and comfortable incomes.  

In contrast George and Muriel Goertzel’s Cradles of Eminence used a different approach. They selected 300 Americans who lived in the 20th century who had two or more books written about them. Their mean IQ was 127. Instead of comfortable middle-class upbringings that were characteristic of Terman’s high IQ children, the Goertzel’s biographies revealed about two-thirds had troubled homes growing up with a parent who was a business failure, psychotic, idiosyncratic, alcoholic, or physically handicapped. 

The Goertzel’s argued that IQ was insufficient for eminence. Eminence required what they called “a neural itch” that stimulated children to focus more intensely on their work, to exercise their imagination and creativity, and to generate the energy to complete tasks and compensate (sublimate in Freudian terminology) for the stress they encountered growing up. 

Not a single one of the 1000 Terman high IQ children ended up with a biography written about him or her. If being the subject of a biography is a measure of eminence, IQ is a poor predictor. IQ is more aptly an academic quotient and not an intelligence quotient. It measures the ability to take tests not the capacity to be innovative or driven to greatness.  

Elof Axel Carlson is a distinguished teaching professor emeritus in the Department of Biochemistry and Cell Biology at Stony Brook University.

METRO photo

By Daniel Dunaief

Daniel Dunaief

One day, you wake up and your kids who called noodles “noonies” are getting ready for college.

No, not exactly. It’s a long journey filled with skinned knees, ripped tee shirts — don’t ask — eye rolling and muttering between clenched teeth. Still, here we are, as our kids prepare to move on from the educational minor leagues. Along the way, we went through numerous milestones. Please find below a few of the phases in our journey.

— Deer in the headlights. I’ve seen deer in my headlights. The only difference between them and us when we first brought our children home is that the deer’s eyes are open much wider. We almost instantly became sleep-deprived. Other than that, we had that frozen not-sure-where-to-move feeling, knowing we had to do something, but not exactly sure what or in what order to take care of those needs.

— Hating everyone. People meant well back in the days when our children were young and cried. Numerous people, who didn’t live with or even know our needy infants, offered unsolicited advice about what this scream or that scream meant. Strangers would tell us how our daughter’s cry meant she had gas, was hungry, needed her diaper changed, or was hot or cold. Yes, thanks, those are the options. Thanks for the help!

— Cooking the plastics. Yup, back in the early days, I was so sleep deprived that I put plastic bottles in a pot of boiling water to sterilize them and fell asleep. It wasn’t until I smelled the burning plastic that I realized how long I’d been out.

— Carrying everything: We couldn’t go four blocks without a diaper bag filled with everything, including the special toy each of them needed, diapers, wipes, ointment, sunscreen, bug spray, rain jackets, boots, and extra clothing.

— Straining our backs: Picking the kids up and playing with them was fun when they were under 20 pounds. When they reached 50 and above, holding them the entire length of a ski slope became impossible.

— Crazy sports parents: This phase lasted much longer than it should have. It was only when the kids reached late middle school that I appreciated the fresh air, the sparkling sunlight and the excitement of the moment. Exercise and making friends are the goal. Everything else, including winning, is gravy.

— Giving them space (aka, it’s not about us). As they reached adolescence, our children needed to make their own decisions. Tempting as it was to jump in and redirect them or even to kiss them before they left the car for middle school, we bit our tongues as often as we could, leaving us feeling lonely and nostalgic in our cars as they joined their friends.

— Beautiful naps: Giving them space allowed us to do what we wanted. After years of living our lives while monitoring and helping theirs, we had a chance to do exactly what we wanted, which started with restorative naps.

— Sending them into space. We aren’t putting them in a Jeff Bezos rocket ship or sending them to the International Space Station, but we are preparing to give them an opportunity to explore the world outside our house.

— Looking at the calendar differently. With both of them on the way to their futures, we can choose places to visit that didn’t interest them. We can visit these places when school is in session, which should mean lower costs for us.

— Telling other people how to take care of their kids: With our free time, we see parents struggling with young children. We, of course, know better. Or maybe not.

METRO photo

By Leah S. Dunaief

Leah Dunaief

At this time of renewed attention to COVID-19, I recommend escapism. I have managed it, and this is how I did it. I immersed myself in two books, one after the other. They weren’t great classics, just hand-me-downs from a person whose reading tastes I respect. He gave me both books, and like a magic carpet ride, they took me to a different time and place with interesting characters for travel companions.

I enjoy historical fiction, and interestingly enough, both books use the siege of Leningrad by the Nazis during World War II as a critical context for their plots. Although we are being laid siege today by a malevolent virus, that act of war almost exactly 80 years ago was far different. Hitler wanted to bomb the city into oblivion, believing that Eastern Europeans were worthless, and survivors were to be starved to death. The German army was under orders not to accept any truce offer that might be extended to them by the city leadership. The siege began on Sept. 8, 1941, and ended, after 872 days of torment, on Jan. 27, 1944. The pre-war population of about two and a half million was reduced at the end to about 800,000 by extreme famine, disease and artillery strikes, one of the most destructive blockades in history. To make matters even worse, that first winter saw temperatures plummet as low as – 40 degrees. The dead piled up in the streets. There were even instances of cannibalism. The survivors were marked forever.

This is a major catalyst of the first book, “Winter Garden,” by best-selling author, Kristin Hannah. It is the story of the relationship between a mother and her two daughters, and between the daughters themselves, that bears the aftereffects of what has been termed by historians as attempted genocide in Leningrad. Anya is a cold and disapproving mother to her children, and they feel cast out to survive emotionally, each in their own way as they grow up. The glue that holds the family together is the father, and when he becomes terminally ill, the dysfunction of the women is clearly revealed. The writing is dramatic and manages to sustain a heart-rending pathos as the plot builds. I tried to keep a dry eye as I read, but in vain. Each continuing episode tugged at my heart and my tears flowed anew with just about every chapter. The surprise ending is a stunner.

Having barely recovered from Hannah’s epic story, I plowed into “City of Thieves,” by David Benioff. Unlike “Winter Garden,” in which the siege of Leningrad is considered for its profound and intergenerational consequences half a century later, Benioff’s main characters deal with the horror as it is unfolding. Seventeen-year-old Lev and 20-year-old Kolya somehow manage to make this into a coming-of-age story, with some laugh-out-loud dialogue even as they are fighting to survive. But don’t be misled. This account of the tragedy of Leningrad is, if anything, more brutal for its contemporaneous setting. 

The two young men, through a bit of incredible yet somehow acceptable events, are sent off by a Soviet colonel amidst a starving city in search of a dozen eggs. It might as well be the holy grail for Arthurian medieval knights. In the course of the quest, they see and sometimes experience some of the individual terrors of the siege in what Benioff claims is historically accurate fashion. Benioff has delineated the plot according to specifics in Harrison Salisbury’s book, “The 900 Days,” and Curzio Malaparte’s “Kaputt.” 

The latter, a novel published in 1946 by an Italian war correspondent, is about the descent of European civilization on the Eastern Front during World War II, and the former, written in 1969, is by the respected American journalist detailing the definitive story of the prolonged battle. Benioff cites them as sources for his novel.

They were hardly light reading, these two books my friend gave me, but they certainly kept my attention. They also taught me a bit, as good books do.