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Stony Brook University

A baby gelada foraging in Simien Mountains National Park in Ethiopia. Their early-life gut microbiome, from infancy through first years of life, are shown to be influenced by bacteria likely passed down from mom. Photo by Sharmi Sen

The bacteria that reside in the human gut (“the gut microbiome”) are known to play beneficial and harmful roles in human health. Because these bacteria are transmitted through milk, mothers can directly impact the composition of bacteria that their offspring harbor, potentially giving moms another pathway to influence their infant’s future development and health. A study of wild geladas (a non-human primate that lives in Ethiopia) provides the first evidence of clear and significant maternal effects on the gut microbiome both before and after weaning in a wild mammal. This finding, published in Current Biology, suggests the impact of mothers on the offspring gut microbiome community extends far beyond when the infant has stopped nursing.

A research team co-led by Stony Brook University anthropologist Dr. Amy Lu, and biologists Dr. Alice Baniel and Dr. Noah Snyder-Mackler at Arizona State University, came to this conclusion by analyzing one of the largest datasets on gut microbiome  development in a wild mammal.

“Early life gut microbial development is known to have a large impact on later life health in humans and other model organisms,” said Lu, Associate Professor in the Department of Anthropology in the College of Arts and Sciences at Stony Brook University. “Now we have solid evidence that mothers can influence this process, both before and weaning. Although we’re not 100% certain how mothers do this, one possible explanation is that they transfer specific bacteria to their offspring.”

The research team used high throughput DNA sequencing to identify and characterize the bacteria residing in the guts of young geladas, and identified 3,784 different genetic strains of bacteria belonging to 19 phyla and 76 families. However, this diversity was not equally distributed across the developmental spectrum: similar to what is seen in humans, younger infants had the least diverse microbial communities that gradually became more diverse as they got older. These changes reflected what the infant was eating, specifically when they switched from consuming milk to consuming more solid foods. These diet-focused bacteria actually help infants process foods – for instance, milk glycans, which cannot be digested without the help of bacteria.

However, it was the team’s findings of strong maternal effects on the infant gut microbiome both before and after weaning that was the most groundbreaking.

“Infants of first-time moms showed slower development of their gut microbiota, meaning that their guts were specialized toward milk digestion for longer compared to kids from other moms. This may put offspring of newer moms at a slight developmental disadvantage,” said Baniel. “In addition, even after infants were weaned, their microbiome community was more similar to mom’s than to other adult females in the population, suggesting that mom’s may be sharing microbes with their offspring.”

According to Snyder-Mackler, “these early life changes might have far-reaching consequences–impacting the health and survival of these offspring once they become adults.”

Future work from this research team will focus on examining how differences in the gut microbiome during infancy influence other aspects of development, such as growth, the maturation of the immune system, or the pace of reproductive maturation. Because they are continuing to study the same infants as they age, they expect to eventually be able to link the infant gut microbiome and the early-life maternal effects to health, reproduction, and survival in adulthood.

The research was funded by several grants from the National Science Foundation, the National Geographic Society, the Leakey Foundation, and from the University of Michigan, Stony Brook University, and Arizona State University.

OLLI members during a tour of SBU on Aug. 31. Photo from OLLI

Joining children and college students across the Island going back to school to study, adult learners also returned to a local campus on Sept. 6.

OLLI members returned to in-person workshops on Sept. 6. Photo from OLLI

After five semesters, Osher Lifelong Learning Institute’s members have returned to the Stony Brook University campus. The program, better known as OLLI, offers a variety of noncredit workshops designed to appeal to people over 50. During the spring semester of 2020, OLLI switched to virtual workshops via Zoom due to COVID-19 shutdowns. The program this fall will once again offer in-person workshops, as well as virtual and hybrid options.

Breanne Delligatti, OLLI at SBU program director, said members had the opportunity to attend an orientation on Aug. 31. More than 100 people were in attendance. This semester there will be more than 600 learners with over 100 courses, lectures and events planned.

Jane Cash, curriculum committee co-chair and workshop leader, described the orientation as extraordinary. A recently retired nurse, she joined OLLI during the pandemic and has only attended via Zoom.

“To see more than people’s heads and shoulders, and to meet them in person, it was really lovely,” Cash said.

Ella Nyc, executive council president, said it was also exciting to see people return who decided not to participate via Zoom either due to lack of technical savviness or proper equipment. 

“They’re still coming back and returning and so excited to be back on campus again,” Nyc said.

While it was good to see each other in person again, Karen DiPaola, curriculum committee co-chair and workshop leader, a member since 2017, said it was amazing how the workshops were quickly made available on Zoom in 2020 considering it was something that couldn’t be anticipated. She took several workshops via the platform.

“It was almost like having them in your room, and now to see them again in person at the orientation was just a delight,” DiPaola said.

Delligatti said they were one of the first Osher institutes to be fully operational with virtual learning. Before the pandemic, virtual workshops were not offered.

OLLI members attend an orientation at SBU on Aug. 31. Photo from OLLI

“Within two weeks of leaving the campus, we had over 50 workshops converted to virtual on Zoom, and that remained and increased every semester for the subsequent five semesters that came,” Delligatti said.

After the Aug. 31 orientation, held in the theater at the univesity’s Charles B. Wang Center, SBU students led the OLLI members on a tour of the more popular spots on campus and where workshops will take place. They also showed the adult learners where they could relax between their workshops.

Delligatti said the members then headed to the computer lab at Research & Development Park where OLLI learners will have access to new computers. The SBU students helped OLLI members set up their credentials to get on Wi-Fi, something members may need if they decide to participate in a virtual workshop while on campus.

Nyc said she is looking forward to members interacting in person again, especially in discussion workshops.

“It’s difficult to have a discussion when you have to wait to be recognized in the waiting room, it’s going to be so much better,” she said. “It’s more impromptu, it’s more fun.”

DiPaola said there were some workshops they could not do remotely, such as ones about board games. She added she enjoys walking between workshops and getting a bite at the cafeteria on campus.

“I also love about OLLI that it’s a place on a college campus, and it’s very energizing to see all of the young students,” DiPaola said.

Cash said it’s interesting meeting people who you have not met otherwise.

“You pass people in the supermarket, and you don’t know anything about them except how they look, but when you get to know them as people and see them as people with great experience and expertise and charming also, I think that’s the beauty of OLLI.”

According to Delligatti, OLLI members raised more than $50,000 over the last couple of years which enabled the program to outfit two classrooms at SBU with new equipment for the members to use.

Image from Stony Brook Athletics
Gift from inaugural football team member to support comprehensive excellence within Department of Athletics

Stony Brook University President Maurie McInnis and Director of Athletics Shawn Heilbron announced that the University has received a $3 million gift from the Kehoe Family Foundation to support comprehensive excellence within the Stony Brook Department of Athletics.
 
The gift was made by the Kehoe Family Foundation which is comprised of Stony Brook football alumnus Kevin Kehoe ’77; his wife Lorraine; brothers Brian, Tim, Michael, and Jeremy; sister Deirdre Chanis; and daughter Julia.
 
“I really enjoyed my years at Stony Brook and playing on the original club football team. I’ve been fortunate in my career to build a couple of businesses which has given me the opportunity to start the Kehoe Family Foundation.
 
You can’t help but take enormous pride in seeing how far Stony Brook Athletics – and the football program specifically – have come. When I looked at where the program is now and where it can be in the future, I saw a great opportunity to make a difference. I’m happy to be even a small part of what will be an amazing journey,” said Kevin Kehoe as he reflected on what Stony Brook means to him and why he was compelled to have his foundation make this gift.  
 
The gift from the Kehoe Family Foundation is the third-largest in department history. The foundation’s donation will fund the replacement of both the north end zone video board and south end zone scoreboard in Kenneth P. LaValle Stadium, launch an Athletics facilities master planning project, support the renovation of the football locker room, and provide operational support to Athletics Career Development & Leadership programming.
 
Through these priorities, the Kehoes’ gift will directly support the department’s vision to positively transform the life of each student-athlete and its mission to elevate the national profile of the University by winning championships; inspiring school pride; and fostering transformational experiences for student-athletes, alumni, and the Long Island community.
 
“I have been inspired to learn about the Kehoe Family Foundation’s approach to generational giving, and Stony Brook University is incredibly grateful for their generosity,” said President McInnis. “The growth of Stony Brook Athletics over the past six decades has been breathtaking, and I’d like to thank Kevin and his family for this meaningful gift, for this wonderful demonstration of team spirit, and for proving, as we like to say at Stony Brook…once a Seawolf, always a Seawolf.” 
 
In recognition of the Kehoe family’s generosity, we are proud to submit to the Stony Brook Council and SUNY Board of Trustees the recommendation that the Kehoe name be displayed within Stony Brook Athletics’ facilities where we plan to name the entryway of Island Federal Arena as the “Kehoe Family Atrium” and the south end zone scoreboard in LaValle Stadium as the “Kehoe Family Scoreboard.”
 
“This is a time of tremendous optimism and opportunity for Stony Brook Athletics, and I’m exceedingly grateful to the Kehoe family for their generous commitment at a time when investment is so critical. This gift addresses several vital needs for our department while providing significant momentum as we enter our first year as an all-sport member of the CAA. As a student-athlete when Stony Brook’s football program was in its infancy, Kevin is now graciously contributing to its continued elevation. I am indebted to him and his entire family for their trust and belief in what we are building,” said Director of Athletics Shawn Heilbron.
 
“We are grateful for the vision and generosity of Kevin Kehoe and the Kehoe Family Foundation. Not only are they strengthening the foundation of Stony Brook Athletics, but as an alumnus and former student-athlete, Kevin’s leadership will go a long way toward inspiring the next generation of Stony Brook students and alumni,” said Vice President for Advancement and Executive Director of the Stony Brook Foundation Justin Fincher. “We look forward to the family’s continued partnership as our Athletics program begins this exciting new phase in its evolution.”
 
Kehoe earned his bachelor’s degree at Stony Brook in 1977 and was a founding member of the university’s football team. As members of the inaugural football team at Stony Brook, Kevin and his teammates were pioneers who laid the foundation for what the program has become 45 years later.  
 
Kehoe was born in New York City but lived much of his life in Southern California, with stops in Florida and Texas. He began his business and consulting career with Coopers & Lybrand in 1984. Nearly a decade later in 1993, he launched his own consulting firm, Kehoe & Co., where he worked until he founded The Aspire Software Company in 2014. In 2021, he sold Aspire to Service Titan, where he retains a position as a consultant.
 
In addition to his successful business career, Kevin is a published author of his memoir, One Hit Wonder: The Real-Life Adventures of an Average Guy and the Lessons He Learned Along the Way.
 
Today, Kevin and his wife of 20 years, Lorraine, live in Arizona.
 
About Stony Brook Athletics:
Stony Brook University’s Athletics Department sponsors 18 varsity intercollegiate athletic programs that compete at the NCAA Division I level. Their world-class facilities include the 12,300-seat Kenneth P. LaValle Stadium, and a sports complex housing the 4,000-seat Island Federal Arena, which opened in the Fall of 2014. All of Stony Brook’s men’s and women’s programs offer athletic scholarships. For more information about the Stony Brook Seawolves, visit stonybrookathletics.com.

Coach Ashley Langford. Photo from SBU

By Daniel Dunaief

Daniel Dunaief

Parents, coaches and teachers offer words of wisdom, guidance and advice.

At the same time, however, they also have opportunities to learn, particularly after the end of one year and the start of another.

And so it is for Stony Brook University women’s basketball coach Ashley Langford.

A year after she took her first head coaching job at Stony Brook, Langford took stock of her experience, while contemplating the next steps.

“I’m still high energy and enthusiastic,” Langford said at 3 p.m. .on the first day of school from her car as she headed to a late lunch. “I’m still excited to be head coach.”

A self-described “high achiever” who “wants to be the best,” Langford acknowledges that she may be an over achiever as well.

“Even when I reach my goal, for me, you’re supposed to,” she said. “There were times [last year] when we would win and I wouldn’t be happy. I want us to be our best.”

Langford, however, recognizes that emphasizing ways to improve, even after winning a game, was not ideal for her players.

“They are 18- to 23-year-olds,” she said. “They need to enjoy that win, regardless of how it looked. They need to be praised right in the moment.”

That doesn’t mean teaching and improving ends after a win. The next day, she said she felt more comfortable talking about how to avoid the possibility of letting a game slip away.

In her second year, Langford hopes she, her coaches and the team become more visible to the community, particularly because the team plays a “fun brand of basketball.”

Her debut season involved ongoing restrictions related to the pandemic, preventing her from connecting with the community.

“I need to be more visible,” Langford said. “It’s important that Long Island knows who we are.”

She is eager to go into schools and engage with members of the community.

“Community service is a huge piece of that,” Langford said. “It’s us going to schools and reading” or interacting in other ways with residents.

This summer, the basketball program ran an elite camp for players who were not at a recruitable age. Participants in the camp can come back to games for free, which, Langford hopes, can encourage other spectators to join them.

“Maybe they’ll bring a friend or two,” she said.

The Seawolves coach is excited for the opportunity to compete in the Colonial Athletic Conference. After participating in the America East conference since 2001, the Stony Brook Athletic Department decided to move to the CAA starting this season.

Langford will rely on some of her knowledge of her competition. Prior to arriving at SBU, Langford spent four years at James Madison University, which is a member of the CAA.

“I know the DNA of certain teams,” Langford said. She recognizes, however, that teams change, which means that the Seawolves have to be “ready to pivot.”

As she prepares the team, which includes four transfer students, for the upcoming season, she believes Stony Brook will be competitive in a demanding conference.

“We’re not in a league where you can have an off night and think you’re gong to win,” she said. “We’ve got to be ready to give our best.”

Thoughts from a former player and her father

Former fifth-year player India Pagan, who is preparing to play professional basketball in Germany this winter (see story in Arts and Lifestyles), remains connected to her former team.

“I’m really proud that we made it to another league,” she said. “We have to elevate our level, our intensity. I say, ‘We,’ like I’m still on the team.” Pagan said she still feels committed to a team she helped lead to consecutive conference championships.

Thinking back to the beginning of his daughter’s college basketball experience, India’s father Moises Pagan cited Stony Brook’s eagerness to recruit her.

“The fact that they put this powerpoint together, it blew us away,” Pagan said. “We walked away saying, ‘Stony Brook really wants our daughter.’”

Arjun Venkatesan is testing an enhanced coagulation approach to treat contaminated water. Photo by John Griffin/Stony Brook University

By Daniel Dunaief

One person’s toilet flush is another’s pool of information.

Arjun Venkatesan, Associate Director for the New York State Center for Clean Water Technology at Stony Brook University, has gathered information from wastewater plants to search for traces of opioids and other chemicals.

Such monitoring is a “great tool” and relies on the sensitivity of the method, Venkatesan said.

Indeed, other scientists, including Professor Christopher Gobler, Endowed Chair of Coastal Ecology and Conservation at the School of Marine and Atmospheric Sciences at Stony Brook, have used wastewater monitoring to collect information about the prevalence of Covid-19 in a community.

Gobler explained that such monitoring has proven to be an “ideal way to track community infections. Through early to mid 2022, positive test rates and wastewater virus levels tracked perfectly. Since then, people began home testing and now, wastewater epidemiology is probably our best sign of community infection rates.”

In a joint effort through the Center for Cleanwater Technology, Venkatesan’s team monitors for chemicals, including opioids and other drugs. Such tracking, which college campuses and local governments have done, does not involve gathering information from any specific home. Instead, the scientists take anonymous samples from a larger dorm or a neighborhood, hoping to track changes in the presence of chemicals or a virus to enable health care mitigation efforts.

Venkatesan has been looking at common over-the-counter drugs and anti-viral treatments that residents used to treat Covid-19 infection, particularly before the development and distribution of several vaccines. He noticed an increase in over the counter use that matched the increase of Covid cases, which suggested that the infected people took these pain medicines for their symptoms first.

Venkatesan’s group monitored the use of these drugs over the last two years to confirm the trends. This baseline allowed him to “see increasing trends” in usage, he said. The increase “clearly indicates something more than what the drugs are regularly used for.”

Opioids

Venkatesan’s group has been working with the Department of Health to develop standard protocols to measure drugs at these sewage treatment plants. The testing needs to be updated to account for changes in consumption of new drugs that are being synthesized.

Each sample Venkatesan and his colleagues collect typically has hundreds of thousands of people in it, because the treatment plants process sewage for a large collection of communities. “This keeps anonymity,” he said. “We don’t want to dig up [information] from a single family home.”

The method is also cost effective when a single sample represents a larger population. This kind of information, however, could help public health professionals monitor the presence of drugs broadly in a community, providing them with a way to track the prevalence of addictive and potentially harmful drugs.

Venkatesan is developing methods to track fentanyl, a highly addictive drug linked to numerous deaths throughout the country and the world. Studies in other regions have demonstrated elevated levels of this drug.

Venkatesan said New York State responded to the pandemic by developing surveillance over the last few years. The approach was not well known and was limited mostly to illicit drugs. The pandemic made a significant impact, which helped officials appreciate the value of such a tool.

The state could also theoretically monitor for any chemicals that are stable enough in sewage.

While Venkatesan hasn’t measured traces of alcohol at sewage treatment plants, researchers and public health officials could create a screen to measure it. He was involved in a study that monitored for alcohol and nicotine consumption in many cities. “We could get interesting trends and understand community and population health in a better way,” he said. The pandemic has “helped establish the importance of this network.”

Surveys in which people call and ask about the consumption of drugs or alcohol can contain self-reporting error, as respondents may not know exactly how much they drink or may be reluctant to share those details.

Wastewater monitoring could capture trends, including whether communities have a spike in the use of drugs or alcohol on Friday nights or on weekends.

The Centers for Disease Control and Prevention created standardized methods for monitoring Covid-19 in the wastewater of cities and states.

Wastewater monitoring techniques are different for detecting viruses compared to chemicals. Venkatesan’s group is developing different method to screen for opioids. “We are excited about it,” he said. “Hopefully, next year, we should be able to monitor communities.”

As long as the sampling doesn’t cross any predetermined ethical line, monitoring could provide an effective way of looking at the trends and data, he said.

With so much water flowing through pipes and treatment plants, one of the biggest challenges in these efforts is to understand variables that affect what the scientists are monitoring.

The time between when a toilet is flushed in an apartment to the time when it reaches a plant can vary, depending on numerous variables, which creates uncertainty in the data.

To reduce this variability, scientists could do some sampling in manholes, between treatment plants.

Scientific roots

Venkatesan took an elective at the end of college in environmental science when he attended Anna University in Chennai, India. It was the first time he observed a wastewater treatment plant.

Fascinated by the process, he earned a Master’s in Environmental Engineering at the University of Nevada, Las Vegas and then went on to get a PhD at Arizona State. He also did his post doctoral research in Arizona.

Stony Brook was looking for a scientist to screen for contaminants in drinking water, including PFAS chemicals, which is a group of chemicals that are stable, hard to break down and are linked to thyroid cancer, among others.

PFAS chemicals are used in cleaners, textiles, fire-fighting foam and other applications.

Venkatesan leads drinking water efforts, while waste water epidemiology remains an ongoing project of interest.

Gobler hired Venkatesan five years ago to help run and then to exclusively run the drinking water initiative at Stony Brook.

Through the process, Venkatesan has “brought new insights and research programs related to wastewater epidemiology, bisolids and many other topics,” Gobler explained. Venkatesan has “exceeded expectations,” as he transitioned from a postdoctoral researcher to become Associate Director for Drinking Water Initiatives.”

Gobler called his colleague a “complete professional” who is “very positive and a good person to work with.”

In his research, Venkatesan develops technologies to remove these PFAS chemicals, while monitoring is also a part of that effort. Activated carbon filters can remove these chemicals from groundwater. These filters, however, require frequent replacement. Venkatesan is exploring ways to improve the life of the carbon filter.

PFAS chemicals make rain water unsafe to drink. Removing PFAS chemicals is an “important research topic locally and globally.”

India Pagan at Stony Brook University with her parents at graduation.

By Daniel Dunaief

With sneakers on her feet and a ball in her hand, India Pagan will circle the globe in a landmark year.

India Pagan
Photo from tStony Brook University

First, she earned a Master’s Degree in coaching at Stony Brook University, completing a five-year stint in which she also received her Bachelor of Arts in Sociology. After a brief journey home to New London, Connecticut to visit with her family and celebrate, she and her family took a long-awaited cruise to Honduras and Mexico. 

Now, the 6-foot,1-inch power forward, who completed a distinguished basketball career at Stony Brook, is practicing with the Puerto Rican National team, with whom she also traveled to the Olympics last year in Tokyo. Pagan and the team will travel to Serbia for a scrimmage and then to Australia to play in the World Cup.

But that’s not the end of her journey. After the World Cup, Pagan, 23, will fulfill a professional goal, as she signed a one-year contract to play professional basketball in Germany with the BC Pharmaserv Dolphins in Marburg, Germany. North of Frankfurt and east of Dusseldorf, Marburg is home to the Marburger Schloss (Marburg castle) and numerous medieval churches.

“It’s always been my dream to play overseas, so it’s a dream come true,” said Pagan, who is listed as a starter for the Division 1 German team. “To get paid to do what I love is really cool.”

The reality of becoming a professional basketball player started to sink in after she told family members she had signed a contract. When she shared the news with her mother Carmen Pagan, her mom “flipped out,” Pagan recalled. Her sisters Melody and Taina and family friends were similarly excited and “freaked out” about Pagan becoming a professional basketball player.

Reaching such a dream requires familial “teamwork,” said Carmen Pagan. “Any family member that is part of that group, everybody has to be committed to be there and support the child in different ways,” including emotionally, financially and academically.

When Pagan started playing basketball at the age of 11, the family made a “huge commitment” that included missing a “lot of birthdays, and a lot of family functions. We were always on the road, traveling throughout the United States” said India’s father Moises Pagan, who credits his daughter’s willingness to seize any opportunity to play as a catalyst for her basketball career.

One Friday night years ago, India received a call about a high school showcase in Queens. Despite heavy rush hour traffic and a five-hour commitment, she “didn’t even twitch,” he recalled. She said, “Dad, I want to go.” That’s where Stony Brook’s previous basketball head coach Caroline McCombs, who led the team from 2014 to 2021, saw her play.

Pagan is one of a few former Seawolf women to become a professional basketball player, joining Kaela Hilaire and Shania “Shorty” Johnson, who have also played in Europe.

Professional connection

After a solid showcase following her season, Pagan received numerous offers from agents to represent her. Choosing an agent was “like picking a school all over again,” she said. “I just had to see who was the right fit.”

Pagan selected Stephanie Stanley, president and founder of Merit Management Group who also represents one of Pagan’s favorite WNBA players, Washington Mystics Guard Natasha Cloud. That, however, was only one of several reasons she chose Stanley. The down-to-Earth Pagan thought Stanley was “like an old auntie. She had me laughing.”

Stanley, whose clients sometimes call “Momma Steph,” said she appreciated Pagan because she “likes players who hustle, play hard and look like they’re having fun out there on the court.”

Stanley also offered advice about the kinds of things to be prepared for when playing overseas. A team told one of Stanley’s clients they would provide transportation. When the player arrived, the team gave her a bicycle. “Lesson learned,” laughed Stanley. The player, however, realized that everyone used bicycles to get around in the country and appreciated the chance to lose a few pounds by pedaling back and forth to practice.

Another client had a choice of prepared meals or a financial allowance for food. The player sent Stanley pictures of food neither of them could identify. Stanley said these rookie contracts cover the cost of living and playing basketball. Rookies are “going to learn how to budget,” she said.

In the bigger picture, Stanley said the overseas market, particularly with Americans no longer comfortable playing in Russia amid the imprisonment and nine-year sentence of Brittney Griner, is having a “rough year.” Players who might have played for a top tier Russian team are heading to Turkey, Italy, Spain or France. The dislocation is affecting leagues around the world at every level. “Any player that signed now is impressive,” Stanley said. “It’s a rough year.”

Stanley added that rookies typically sign for one year in any league as players look to advance to more competitive leagues where they might also earn more money.

Pagan, who will be sharing an apartment with three other players when she arrives in Germany a day or so before the team’s first game, is excited for the opportunity and feels like the team and coach Patrick Unger, who lived in the United States for a year, support her. Unger has reached out to her on FaceTime. 

At the same time, the team, which consists of several German players, includes players who speak English. The team pays for utilities, housing and transportation and is providing money for groceries.

While Pagan is excited to get on the floor and start playing with her new teammates, she knows she needs to contribute. “I have to prove myself,” she said.

SBU contributions

India Pagan
Photo from the Pagan family

If Pagan finds the same kind of success in professional basketball that she had at the college level, she could be starting a promising career. She ranks eighth on the all-time scoring list at Stony Brook University, second in career field goal percentage and eighth in total rebounds.

Ashley Langford, head coach of a Seawolves team that won the America East conference championship last year in her debut season, was pleased for Pagan. “It’s awesome,” Langford said. “It’s what she’s been striving for her whole career.”

Langford appreciated the contributions on and off the court that Pagan made and the work her former basketball stand out put into enhancing her game. On the court, Pagan was “always really skilled,” said Langford. In the last year, she asserted herself more physically, moving closer to the basket and drawing contact from defenders, Langford said. She enjoyed watching Pagan show emotion on the court, flexing after she created contact and heading to the free throw line for a chance at a conventional three pointer.

Off the court, Langford admired the leadership role Pagan took in welcoming newer teammates, showing them around campus, offering advice about college athletics and helping them feel like a part of the Seawolves family and basketball program.  “That’s not me or anyone else telling her, ‘You need to connect with freshman.’ That’s her doing it on her own. That’s who she is. She wants everyone to do well,” said Langford.

Pagan encouraged her new teammates to snack because players don’t always have time for a structured meal and encouraged them to “use academic advisors wisely,” she said. “They’re there for a reason.”

While Pagan is excited about the next stage in her life, she is grateful for the time and opportunities she had at Stony Brook. “Eventually, that chapter had to end,” she said. The Stony Brook team will “always be a family.”

Growing fame

Pagan, who joined the Puerto Rican women’s team at the delayed 2020 Olympics last year in Tokyo, has started to develop an international fan following. Recently, she was at a WalMart in Puerto Rico and someone walked up to her and asked to take a picture with her. While Pagan was born and raised in Connecticut, she plays for Puerto Rico because both her parents are from Puerto Rico.

She  was also recently eating at a Chili’s restaurant with her teammates when an interview she did appeared on TV screens around the restaurant. “The waiter was like, ‘Oh my God, that’s you,’” Pagan said. Her teammates enjoyed the excitement.

Pagan has also received and responded to messages in German on social media. Once her professional season starts in Germany, Pagan will be far from home, where her parents can’t take the Bridgeport or Orient Point ferry to come see her the way they did at Stony Brook, a place the entire family still feels at home.

Indeed, one of the more emotionally challenging moments during her world-traveling basketball journey occurred when she played in Chile for three weeks. At 17, Pagan found it difficult to be so far from family, Moises Pagan recalled. That experience prepared her for her current plan to travel to Germany. “It makes the transition [to Germany] so much easier,” he said. FaceTime and a commitment to basketball have allowed Pagan to focus on her sport. “She just wants to make everyone proud, playing the game she loves,” he added

The Center for Italian Studies at Stony Brook University, 100 Nicolls Road, Stony Brook offers Italian classes for the community from October, 2022 to April, 2023. The informal studies program for adults is designed to expose participants to the Italian language and culture.  On-line courses using video conferencing and distance learning technologies are offered in Beginner, Elementary, Intermediate, and Advanced Italian; each level offered in a 22-2 hour series of classes  (44 hours of instruction). Cost per course is $300.  For additional information/registration form, class dates, times and schedule view www.stonybrook.edu/italianstudies or call 631-632-7444.

This rendered image of the brain via a technique called diffusion tractography reveals parts of the brain’s white matter in a compilation of WTC responders experiencing cognitive impairment (CT). These areas depicted by various colors illustrate where the brain is more vulnerable to neurodegenerative processes. The different colors represent differences in the heath of various parts of the brain including the limbic system. Credit: Chuan Huang
Stony Brook-led imaging study sheds light on PTSD-associated mental decline

A study that assessed the brains of 99 World Trade Center (WTC) responders by using diffusion tractography, a 3-D imaging technique, showed that WTC responders with cognitive impairment (CI), a possible sign of dementia, and post-traumatic stress disorder (PTSD), have a different presentation of the white matter in their brains compared to responders with CI without PTSD. Led by researchers at Stony Brook University affiliated with the Stony Brook WTC Health and Wellness Program, the study suggests a specific form of dementia could be affecting WTC responders who also have PTSD. The findings are published early online in the Journal of Alzheimer’s Disease.

According to the authors, this is the first study to examine white matter alterations using connectometry in a sample of WTC responders in mid-life (average age: 56) with and without concurrent PTSD. The goal of the study was to examine and elucidate the extent to which white matter tract integrity might be impaired in WTC responders with CI and/or PTSD. Previously, the researchers had identified changes in white matter diffusivity in small numbers of responder patients.

“Our findings are by no means conclusive in terms of defining CI or dementia in WTC responders, and if this study provides evidence of a new form of dementia emerging,” says Sean Clouston, PhD, lead author and Associate Professor in the Program in Public Health, and in the Department of Family, Population, and Preventive Medicine at Stony Brook University.

“Overall, the study supports the view that responders with CI have neurological changes consistent with neurodegenerative disease, but they are inconclusive as to the type of disease,” he adds. “Our findings do show that dementia due to PTSD is clearly different from non-PTSD dementia in this responder population.”

Subjects in the study were matched by age, gender, occupation, race and education. Cognitive status was determined by using the Montreal Cognitive Assessment, and PTSD status was determined by using the Diagnostics and Statistics Manual-IV. The researchers used diffusion tensor imaging via a mMR scanner, and they used connectometry to examine whole-brain tract level differences in white matter integrity as reflected by fractional anistrophy (FA) values.

In summary, the team found that FA was negatively correlated with CI and PTSD status in the fornix, cingulum, forceps minor of the corpus callosum, and the right uncinate fasciculus. Additionally, FA was negatively correlated with PTSD status, regardless of the CI status in the superior thalamic radiation and the cerebellum.

The authors conclude that the brain imaging results “suggest that WTC responders with early-onset CI may be experiencing an early neurodegenerative process characterized by decreased FA in white matter tracts.”

The technique and other findings

Clouston and colleagues used the imaging technique diffusion tractography to examine how healthy axons are in the brain’s white matter. The technique helped to determine that responders with CI had signatures in their white matter that did not match patterns seen in old-age Alzheimer’s disease and other related dementias.

By using the imaging technique, they also compared responders with PTSD and dementia to those with dementia but without PTSD. The imaging revealed a lot of similarities between the groups but also showed a remarkable difference in the white matter of those with PTSD and dementia – showing evidence of cerebellar atrophy, a finding that is inconsistent with other studies of dementia.

The research for the study was supported in part by the National Institutes of Health’s National Institute on Aging (grant # R01AG049953), and the Centers for Disease Control and Prevention (grant # U010H011314) and the National Institute for Occupational Safety and Health, NIOSH, (grant # 200-2011-39361).

 

Jim and Jacqueline Olsen

By Daniel Dunaief

When Jacqueline Olsen learned the day before her birthday last November that she needed surgery for lung cancer, she felt anxious about a procedure she knew could be painful and could involve a lengthy recovery.

“It’s not only my birthday, it’s Thanksgiving,” said Olsen, who is a resident of St. James and is an agent for personal insurance such as home, auto and umbrella insurance. “Everybody was real tense. It was not a pleasant holiday.”

Olsen’s father, William Leonard, and father-in-law, James Olsen, had died of lung cancer after having open chest surgeries. The pain of what her father went through 48 years ago and father-in-law over 20 years ago was fresh in her mind as she readied herself for her own procedure.

Dr. Ankit Dhamija

Speaking with doctors at Stony Brook University Hospital, Olsen heard about newer, better options.

Dr. Ankit Dhamija, Cardiothoracic Surgeon and Director of Thoracic Robotic Surgery at Stony Brook Medicine, suggested to Olsen that she was a candidate for a robot-assist surgery called the da Vinci Surgical System. 

Olsen and her family gathered considerable information about the procedure.

“I did some research on it and it said it would be a faster recovery and I would be up and back to my normal self pretty soon afterward,” said Olsen. “It seemed like a less invasive surgery.”

The robotic surgery does not involve turning over the procedure to a machine, Dr. Dhamija explained.

Instead, the process involves making considerably smaller incisions and guiding the robot through the body to remove the cancerous tissue.

“The robot is a machine that is an extension of our hands,” said Dr. Dhamija, who has performed about 500 such procedures with the help of a robot, including around 70 since he arrived at Stony Brook.

The robotic system allows surgeons like Dr. Dhamija and Dr. Henry Tannous, Cardiothoracic Surgeon and Chief of the Cardiothoracic Surgery Division at Stony Brook Medicine, among others, to sit in the operating room with the patient while the robot enters through an incision. The robot provides a three dimensional view of the inside of the body, magnifying cells by ten times.

The robot assist can also improve the ability of surgeons to perform fine operations.

The system “does have a machine algorithm associated with it that actually is known to reduce tremors in surgeons that have tremors,” said Dr. Dhamija. “Someone that may not be able to do a certain portion of the operation due to their technical limitations can subsequently do it with the robot.”

Dr. Henry Tannous

In the procedure, the surgeon can see and maneuver through the body effectively, searching for the specific cells to remove.

An interventional radiologist can inject a dye which under CT guidance allows the surgeon to “see where the lesion is and to verify that you have adequate margins” or the border between cancerous and non-cancerous cells, Dr. Dhamija said. “Having the dye in there to identify [the cancer] is helpful,” he added.

By using the robot instead of creating a large incision, doctors can reduce the time patients spend in a hospital down to as little as one to three days from the four to eight days after an open chest lobectomy.

“There’s so much to be said about someone [recovering] in their own home,” said Dr. Dhamija. They “get to sleep properly, their bowel habits are more normal, and they get to reengage in their daily life functions sooner. I’m a big proponent of a patient taking charge of their own postoperative care.”

Indeed, Stony Brook doctors have become so confident and comfortable with the robot assist that it has become the main platform for thoracic oncology patients at Stony Brook Medicine, explained Dr. Tannous. Tannous estimates that 90 percent of the lobectomies will be performed robotically in 2022, up from 10 to 20 percent in 2021.

In an email, Dr. Tannous wrote that other specialties that have adopted the robotic platform include gynecology, urology, colorectal, bariatrics, and general surgery.

Stony Brook is also expanding robotic surgery to include cardiac procedures in 2023.

Dr. Tannous said robotic procedures that cut down on recovery time means less risk of hospital-acquired infections, lower extremities blood clots, and numerous other benefits.

Some day, theoretically, the robot may enable remote procedures, with surgeons operating the robot with the help of an on-site local medical team. That could be helpful for astronauts who develop a medical problem far from home where they need emergency surgery.

An important caveat with that, Dr. Dhamija said, is that the staff on site would need to be able to complete a procedure if an open chest surgery became necessary.

Olsen, who was out of the hospital less than 24 hours after she had surgery in late May, has become a fan of the technology and of the team at Stony Brook.

Olsen, who has three scars on her back and two on her side, felt pain for about a week. As she recovered, she never felt the need to fill a prescription for a stronger painkiller, choosing to treat the pain with Motrin. She plans to continue to take blood tests every three months and to get CAT scans every six months.

Olsen was thrilled with the quality of care she received and is pleased she can look forward to sharing quality summer time during the family’s annual beach trip. “It’s heaven to me,” she said, where she can “spoil my grandchildren.

As for a perspective on her surgery, she said the difference between 20 years ago and now is “unbelievable. It was such an awful experience” for her father and father in law. “This was a million times better.”

Image from Stony Brook University

Amid the sound and fury signifying nothing, to borrow from William Shakespeare, Stony Brook University’s School of Communication and Journalism has joined a national solutions journalism program.

Stony Brook, NY; Stony Brook University: School of Journalism’s Dean Laura Lindenfeld

That means the journalism school will teach its students how to do much more than complain or highlight issues or problems.

Instead, the school will teach developing journalists how to use data, tell compelling stories and search for answers to problems that are as broad and challenging as climate change and institutional racism, among others.

The solutions journalism hub is “going to help attract people to the field [and provide] a sense of learning from each other,” said Laura Lindenfeld, dean of the Journalism School. “I’m really proud that we’re the hub in the northeast.”

The other journalism hubs include the University of Georgia, Northwestern University and Arizona State University.

“These new hub universities are showing a serious commitment to leading this important work in their regions and nationally,” Francine Huff, Solutions Journalism Network’s director of journalism school partnerships, said in a statement. These four journalism schools have an amazing wealth of talent and resources, and the Solutions Journalism Network is excited to partner with them.”

While SJN provides no monetary gain to the schools, Lindenfeld would like to pursue fundraising around this designation.

Being a part of the solutions journalism network “signals to the community of journalism and foundations about what we care about and what we are about,” Lindenfeld said. “A tighter focus and mission is advantageous and genuine.”

Lindenfeld plans to have ongoing interactions with the other three hubs as a part of a learning community.

To be sure, the concept of using data and sharing compelling stories as a part of a solutions driven journalism effort isn’t new to SBU’s journalism effort.

“We were already doing a chunk of this,” Lindenfeld said. The designation ensures the school is more specifically focused on this, even as Stony Brook will still teach other forms of journalism. “It marks a commitment to making sure we are doing deep, rich storytelling that’s data driven and is looking at a response to problems, rather than just pointing them out.”

Solutions journalism can help drive the focus of stories in an increasingly complex and contentious world, the SBU dean continued.

SBU doesn’t plan to replace balance and professionalism with solutions.

“We are not talking about advocacy journalism or advocacy communications,” Lindenfeld said. “We are talking about the highest standard of ethical journalism that seeks fair, balanced perspectives.”

Lindenfeld urges students to figure out if the data supports or refutes any hypothesis they have about a story.

“You’ve got to always be open to the idea that you could be wrong,” she said. “Trust but verify.”

Solutions journalism includes an understanding of history and context.

Stony Brook has integrated a data analysis and storytelling class into the undergraduate curriculum, where the school helps students dig deeper into how to analyze and tell stories about data.

Solutions journalism will become a cornerstone of the master’s program, Lindenfeld said.

Lindenfeld believes this approach to journalism and communication, regardless of the eventual field graduates enter, should help alumni secure jobs.

“How can it hurt to have a better understanding of data analysis?” Lindenfeld asked.

Down the road, she would like to have an endowed chair in solutions journalism at Stony Brook.