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Stony Brook University

Escobar-Hoyos, center, holds her recent award, with Kenneth Shroyer, the chairman of the Department of Pathology at Stony Brook on the left and Steven Leach, the director of the David M. Rubenstein Center for Pancreatic Cancer Research on the right. Photo by Cindy Leiton

By Daniel Dunaief

While winter storm Niko in February closed schools and businesses and brought considerable precipitation to the region, it also coincided with great news for Luisa Escobar-Hoyos, who earned her doctorate from Stony Brook University.

Escobar-Hoyos, who is a part-time research assistant professor in the Department of Pathology at Stony Brook University and a postdoctoral fellow at Memorial Sloan Kettering Cancer Center, received word that she was the sole researcher selected in the country to receive the prestigious $600,000 Pancreatic Cancer Action Network–American Association for Cancer Research Pathway to Leadership Award.

When she heard the news, Escobar-Hoyos said she was “filled with excitement.” After she spoke with her husband Nicolas Hernandez and her current mentor at MSKCC, Steven Leach, the director of the David M. Rubenstein Center for Pancreatic Cancer Research, she called her parents in her native Colombia.

Her mother, Luz Hoyos, understood her excitement not only as a parent but as a cancer researcher herself. “My interest in cancer research started because of my mom,” Escobar-Hoyos said. Observing her example and “the excitement and the impact she has on her students and young scientists working with her, I could see myself” following in her footsteps.

The researcher said her joy at winning the award has blended with “a sense of responsibility” to the growing community of patients and their families who have developed a deadly disease that is projected to become the second leading cause of cancer-related death by 2020, according to the Pancreatic Cancer Action Network, moving past colorectal cancer.

The Pancreatic Cancer Action Network has awarded $35 million in funding to 142 scientists across the country from 2003 to 2016, many of whom have continued to improve an understanding of this insidious form of cancer.

David Tuveson, the current director of the Cancer Center at Cold Spring Harbor Laboratory, received funds from PanCan to develop the first genetically engineered mouse model that mimics human disease. Jiyoung Ahn, the associate director of the NYU Cancer Institute, used the funds to discover that two species of oral bacteria are associated with an over 50 percent increased risk of pancreatic cancer.

Over the first decade since PanCan started awarding these grants, the recipients have been able to convert each dollar granted into $8.28 in further pancreatic cancer research funding.

In her research, Escobar-Hoyos suggests that alternative splicing, or splitting up messenger RNA at different locations to create different versions of the same protein, plays an important part in the start and progress of pancreatic cancer. “Her preliminary data suggest that alternative splicing could be associated with poorer survival and resistance to treatment,” Lynn Matrisian, the chief science officer at PanCan, explained in an email. “The completion of her project will enhance our understanding of this molecular modification and how it impacts pancreatic cancer cell growth, survival and the progression to more advanced stages of this disease.”

Escobar-Hoyos explained that she will evaluate how mutations in transcriptional regulators and mRNA splicing factors influence gene expression and alternative splicing of mRNAs to promote the disease and aggression of the most common form of pancreatic cancer. Later, she will evaluate how splicing regulators and alternatively spliced genes enriched in pancreatic ductal adenocarcinoma contribute to tumor maintenance and resistance to therapy.

Escobar-Hoyos will receive $75,000 in each of the first two years of the award to pay for a salary or a technician, during a mentored phase of the award. After those two years, she will receive $150,000 for three years, when PanCan expects her to be in an independent research position.

Escobar-Hoyos said her graduate research at Stony Brook focused on ways to understand the biological differences between patients diagnosed with the same cancer type. She helped discover the way a keratin protein called K17 entered the nucleus and brought another protein into the cytoplasm, making one type of tumor more aggressive.

While Escobar-Hoyos works full time at Memorial Sloan Kettering, she continues to play an active role in Kenneth Shroyer’s lab, where she conducted experiments for her doctorate. She is the co-director of the Pathology Translational Research Laboratory, leading studies that are focused on pancreatic cancer biomarkers. The chair in the Department of Pathology, Shroyer extended an offer for her to continue to address the research questions her work addressed after she started her postdoctoral fellowship.

“When you do research projects and you develop them from the beginning, they are like babies and you really want to see how they evolve,” Escobar-Hoyos said. Numerous projects are devoted to different aspects of K17, she said.

Shroyer said Escobar-Hoyos had already been the first author on two landmark studies related to the discovery and validation of K17 even before her work with pancreatic cancer. “She has also conducted highly significant new research” that she is currently developing “that I believe will transform the field of pancreatic cancer research,” Shroyer wrote in an email.

Shroyer hopes to recruit Escobar-Hoyos to return to Stony Brook when she completes her fellowship to a full-time position as a tenure track assistant professor. “Based on her achievements in basic research and her passion to translate her findings to improve the care of patients with pancreatic cancer, I have no doubt she is one of the most promising young pancreatic cancer research scientists of her generation,” he continued.

Yusuf Hannun, the director of the Stony Brook Cancer Center, said Escobar-Hoyos’s work provided a new and important angle with considerable promise in understanding pancreatic cancer. “She is a tremendous example of success for junior investigators,” Hannun wrote in an email.

Escobar-Hoyos said she is hoping, a year or two from now, to transition to becoming an independent scientist and principal investigator, ideally at an academic institution. “Because of my strong ties with Stony Brook and all the effort the institution is investing in pancreatic research” SBU is currently her first choice.

Escobar-Hoyos is pleased that she was able to give back to the Pancreatic Cancer Action Network when she and a team of other friends and family helped raise about $4,000 as a part of a PurpleStride 5K walk in Prospect Park earlier this month.“I was paying forward what this foundation has done for me in my career,” she said.

Matrisian said dedicated scientists offer hope to patients and their families. “Researchers like Escobar-Hoyos spark scientific breakthroughs that may create treatments and ultimately, improve the lives of patients,” she suggested.

It was a rainy afternoon April 22, but that didn’t stop local residents along with Stony Brook University students and faculty members from participating in a March for Science rally at the school. Similar marches took place across the country as Americans joined together to show their support for federal funding for science, as well as to remind President Donald Trump (R) and his appointees how important science is, especially when it comes to researching climate change issues.

Pamela Block, of Setauket, and professor of disabilities studies at Stony Brook University, organized the march with Jenn Solomon, a bilingual speech language pathologist. During a phone interview, Block said approximately 500 people participated, and the marchers ranged in age from young children to senior citizens. Block said the organizations Moms Demand Action for Gun Sense in America, the Audubon Society, the United University Professions and others had representatives on hand.

Block said she and Solomon were talking to a group of local activists including Shoshanna Hershkowitz of Suffolk Progressives and Cindy Morris of Time2Care Long Island, when they decided to organize the April 22 march.

“This is my first time really doing this kind of activist organizing,” Block said. “It feels pretty good.”

The Setauket resident said because she lives in the area and works at the university, the event was a personal one for her. Her mission was to focus on the important part the university plays in the community, as well as in the world of science.

“It was awesome to see the strong turnout, and to be surrounded by thoughtful people who care deeply about the environment and understand the importance of science for our survival and our humanity.”

— Jenn Solomon

“It was a circle of support for Stony Brook in gratitude for the work that it does in the areas of science — medical science, engineering science, environmental science, physics,” she said. “It does some really important work, and I wanted to acknowledge that.”

Solomon credited Block with leading the effort, but like Block, she was excited to be part of the event.

“It was awesome to see the strong turnout, and to be surrounded by thoughtful people who care deeply about the environment and understand the importance of science for our survival and our humanity,” Solomon said.

Morris, who lives in Stony Brook, said a coalition of community groups joined forces a few months ago to reach out in progressive ways to U.S. Rep. Lee Zeldin (R-Shirley) regarding various issues, and the groups have been planning local events to raise awareness about other current issues.

“This march in particular, we felt at the national level we were seeing the March for Science, but we needed to make sure there was accessibility so local people could also participate without going all the way into New York City or all the way to Washington D.C.,” Morris said.

She said it felt great to take part in the rally, and noted the attendees were different from those who normally come out to protest at similar rallies.

“There were enormous numbers of families who were there to talk about clean water and clean air,” she said. “It was a community that really had the opportunity to speak knowledgeably about this issue, and from that perspective, it was empowering to be among people who really understand the importance and really take it to heart.”

Block said rally participants contributed in many ways, even if they were unable to walk the three-mile route along the Circle Road bike path at the university. Many set up stations to cheer marchers on or were available to drive if anyone fell behind in the marching due to physical demands or having children with them.

“As Stony Brook faculty and a Three Village resident, I am proud of how our community is standing up for science.”

— Shoshanna Hershkowitz

Hershkowitz was just one of the participants who attended the march with her family, which includes her four children.

“As Stony Brook faculty and a Three Village resident, I am proud of how our community is standing up for science,” Hershkowitz said. “Given that our area is a major research hub between Stony Brook University and Brookhaven National Lab, we’re in a unique position to speak to this issue. I attended with my children and with another family, because I think it’s important that my kids see activism modeled, and that they know it is part of our duty as citizens to speak truth to power. While bringing kids to events like these isn’t easy, it’s an important lesson that I want to impress upon my kids as a parent.”

Genna Tudda, who has advanced degrees in the sciences and is a 2012 graduate of SBU, said the march hit home for her. While she originally was planning to attend the New York City march, she said, as a Long Island native, it was important for her to show “that people out in the suburbs care just as much about these issues as people in larger cities.”

“Scientific research and environmental issues seem to have been put on the back burner in this new administration,” Tudda said. “Seeing this many people show up to a local event was extremely empowering. I feel hopeful that with these numbers it may be possible to persuade our politicians in the right direction.”

Christopher Forella, standing, third from left, and Dhaval Shah, standing, third from right, with fellow members of Pi Lambda Phi at the Open Door Exchange. Photo from the Open Door Exchange

One fraternity at Stony Brook University has opened the door to a new volunteer adventure that benefits families in need.

When Christopher Forella, a member of the fraternity Pi Lambda Phi at Stony Brook University, was searching the school’s Handshake database for volunteer opportunities, he came across the Open Door Exchange furniture bank. The fraternity’s vice president of programming and risk management said he knew it would be the perfect place for his fraternity brothers to volunteer at this spring semester.

Pi Lambda Phi members from Stony Brook help with the Open Door Exchange. Photo from Open Door Exchange

“I really liked their mission — getting furniture and donating it to people who need it, helping people in need who really can’t afford it,” Forella said in a phone interview.

The Open Door Exchange is an outreach program that allows the underprivileged to shop for furniture free of charge at their Port Jefferson Station warehouse. Kate Jones Calone, a Presbyterian minister affiliated with the Setauket Presbyterian Church, manages the organization. When she heard the fraternity brothers were willing to volunteer at the warehouse, she said she was thrilled.

“It’s especially exciting for us to be able to connect with the university,” Calone said. “The Open Door Exchange really is a community-based project, and the university is such an important part of our community. To be able to work together with students on something that benefits the whole community is a really nice gift for us.”

For Sanjay Jonnavithula, a senior at SBU and a member of the fraternity since it was founded in 2014, the experience of helping those in need to acquire furniture for free has been a rewarding one.

“Furniture is often overlooked as a vital ingredient for a stable household, so it makes me feel incredible that our fraternity is able to aid this great organization in the work that they do,” Jonnavithula said.

The senior said the experience is one that will stay with him even after graduating from SBU, and he believes it has made a positive impact on his fraternity brothers as well.

“I’m sure I speak for all graduating seniors in Pi Lambda Phi when I say that the amount of different community service projects we’ve been a part of, especially Open Door Exchange, has tremendously influenced our lives,” he said. “We are all diverging on our separate paths next year, but we will continue to aid our local communities and get involved with the local charitable organizations in whatever way we possibly can.”

Dhaval Shah, junior at the university and fraternity president, said this type of volunteer work is different from the beach cleanups and assisting at a Head Start preschool like the group has done in the past.

“Something like Open Door Exchange, we see results right away,” Shah said. “We see people coming in and taking the furniture, and the impact on their lives.”

“Furniture is often overlooked as a vital ingredient for a stable household, so it makes me feel incredible that our fraternity is able to aid this great organization in the work that they do.”

— Sanjay Jonnavithula

Forella said the fraternity has 46 members, and when it comes to volunteering every other week at the warehouse for three to four hours, they usually will have about a dozen members working together depending on their schedules. Most of the students help to unload furniture from trucks, but some go out with the loading trucks to pick up donations.

“It’s really making good use of my time to be out helping people who can definitely use the help,” Forella said.

Calone said the other volunteers with Open Door Exchange have enjoyed working with the college students, and they have brought a lot of energy and enthusiasm to the project.

“They’ve extended our capacity to do what we do in a really meaningful way,” the minister said. “It has a real big impact on what we’re able to do.

Calone is even more appreciative of the time the fraternity brothers have given the organization because she understands how valuable free time is to college students.

“They’re taking time out of their weekend, and it’s precious time for students,” she said. “And giving back to the community, that’s something just really nice for all of us to see what the university brings and how it benefits all of us. These students — the way they are giving back — is just really nice for the community as a whole.”

At the first meeting of the HiTOP consortium. Kotov is in the center. Photo from HiTOP consortium.

By Daniel Dunaief

Instead of lamenting the shortcomings of a system they felt didn’t work as well as it should, Roman Kotov and a growing group of collaborators whose numbers now exceed 50 decided to do something about it. An associate professor of psychiatry at Stony Brook University, Kotov and his collaborators are building their own mental health tool, which, they hope, will offer specific diagnoses for everything from anxiety to schizophrenia.

Roman Kotov. Photo from SBU School of Medicine

The current resource psychologists and psychiatrists use is called the “Diagnostic and Statistical Manual of Mental Disorders 5,” which came out in 2013. The latest version of the DSM, as the manual that offers psychologists and psychiatrists a way to link a collection of symptoms to a diagnosis is called, “felt far too limited,” Kotov said. “Once we started discussing [an alternative], almost everyone was interested in the scientific community. They thought it was a good and necessary idea.”

Called the Hierarchical Taxonomy of Psychopathology, or HiTOP, the developing classification system uses scientific evidence, illness symptoms and impaired functioning in its diagnoses. Another HiTOP co-creator, David Watson, the Andrew J. McKenna Family professor of psychology at the University of Notre Dame, recognized Kotov’s important early work on the project.

Kotov “deserves sole credit for the idea of putting all of our data together to provide the basis for an alternative model,” Watson explained in an email. “He did some preliminary work along these lines, which convinced us that this was a great idea that was worth pursuing.” Watson, who served as Kotov’s graduate adviser at the University of Iowa, said that his former student leads meetings and conference calls for the HiTOP group.

The HiTOP system, which was recently described in the Journal of Abnormal Psychology, views mental disorders along a spectra, while also using empirical evidence to understand overlap among disorders and classify different symptoms within a given diagnosis. As an example, Kotov said that depression in the DSM is “treated as one thing. We know that depression is heterogeneous.”

Indeed, some people with depression may have lost their appetite and have trouble sleeping, while others may be eating and sleeping considerably more than they would if they weren’t depressed. “In some ways, these are opposite presentations, yet they get the same diagnosis” in the DSM, Kotov said.

HiTOP unpacks this variability into seven dimensions, which describe symptom types. That is helpful not only for a diagnosis but also for a treatment. HiTOP also goes beyond the binary description of the presence or absence of a particular symptom, offering clinicians a way of indicating the severity of a problem. At this point, HiTOP is a developing prototype and not a completed diagnostic tool. The scientists developing this tool have made inroads in four primary areas: anxiety and depression, substance use problems, personality problems and psychotic disorders.

“The HiTOP system currently is incomplete, as it primarily focuses on more common and widely studied forms of psychopathology,” Watson suggested, “but mental health professionals certainly could use it to assess/ diagnose a broad range of conditions.” Mental health professionals can view this new resource at the website https://medicine.stonybrookmedicine.edu/HITOP.

Kotov hopes this new paradigm will “focus on science and do everything we can to keep unpolitical, nonscientific considerations out of it,” he said. “We hope that it provides the most up-to-date alternative” to the DSM. The HiTOP approach, Kotov said, relies more heavily on scientific evidence, which can include genetic vulnerabilities, environmental risk factors and neurobiological abnormalities.

Kotov, who is working on several projects, said HiTOP takes about a quarter of his time. He is also involved with a long-term study of schizophrenia and bipolar disorders, which was started in the early 1990s, before he arrived at Stony Brook in 2006.

Kotov is following up on this cohort, looking at outcomes for treatment and analyzing risk factors and processes that determine the course of an illness. He is also leading a study on first responders to the 9-11 attack on the World Trade Center, which is exploring the physical and emotional consequences of participating in the response to the unprecedented attack.

Kotov and his collaborators are investigating the health of responders in their daily life using mobile technology. They are also studying how personalities affect their health, which may soon help guide personalized treatment.

Another project involves the study of children who are 14 to 17 years old and explores the emotional growth and personality development. This study includes reports, surveys and interviews. During those years, “much happens as far as personality development,” Kotov said.

Colleagues at Stony Brook praised Kotov’s scientific contributions. Kotov is a “rising star” and is “perhaps best known for his work on the role of personality in psychopathology and, increasingly, for work on classification of psychiatric disorders,” Daniel Klein, a distinguished professor in the Department of Psychology at Stony Brook, wrote in an email.

A resident of Port Jefferson, Kotov lives with his wife Tatiana, who is a controller for a small company in Manhattan. The couple has two young daughters. Kotov grew up in Russia in a small town near Moscow. He was always interested in science and developed a particular curiosity about psychology when a high school psychology teacher sparked his interest when he was 15.

As for the HiTOP effort, Kotov is convinced this endeavor will offer the mental health community a valuable tool. “We believe that describing patients more accurately, precisely and reliably will help provide better and more personalized care,” he said.

Ryan Madden from the Long Island Progressive Coalition leads a march calling for renewable energy in the form of wind. Photo from Ryan Madden

Scientists and politicians are relied upon to do the bulk of the work to reduce the effects and pace of climate change, but local activist organizations on Long Island are taking on the burden as well.

“I think it’s really important for grassroots and local solutions to tackle this crisis — to be at the forefront of the solutions,” Ryan Madden, with the Long Island Progressive Coalition said. “A lot of the problems we see in this country, in New York State and on Long Island, whether it’s rampant income inequality, access to education, just issues of local pollution and ailments related to the combustion of fossil fuels, all of this connects into a larger system that informs why climate change is a problem in the first place.”

The LIPC, a community-based grassroots organization that works on a range of issues related to sustainable development as well as achieving social, racial and economic justice, has a program for improving energy efficiency. The group helps low- to moderate-income homeowners take advantage of free energy assessments and obtain financial resources to be able to go through energy-efficient retrofits and ultimately help reduce carbon footprints. The organization also recently entered the solar arena.

Members of Sustainable Long Island’s youth-staffed farmers market in New Cassel. Photo from Gabrielle Lindau

“It’s part of a larger push to democratize our energy system so that communities have a say in the build out of renewable energy and have ownership or control over the systems themselves,” Madden said. “We’re pushing for constructive and far-reaching changes, which is what we think is needed in this time.”

Madden added he has fears about the future because of comments President Donald Trump (R) has made in the past regarding climate change and his previously stated belief it is a hoax. Trump signed an executive order March 28 that served as a rollback of the Clean Power Plan, an initiative meant to reduce carbon pollution from power plants. The order infringes on commitments to the Paris Agreement, a universal, legally binding global climate deal.

“We’re trying to meet that with really bold, visionary climate policy that has a wide range of economic transformative impacts, while also remaining on the ground helping homeowners and institutions make that switch through energy efficiency and renewable energy,” Madden said.

Other organizations like the Sierra Club, a nonprofit, are also focused on renewable energy, but in the form of offshore wind.

“Offshore wind is the best way to meet our need for large-scale renewable energy that can help us fight climate change and provide good jobs for New Yorkers, but we aren’t used to getting our energy this way in the United States,” Sierra Club organizer Shay O’Reilly said. “Instead, we’re used to relying on dirty fossil fuels, and our energy markets and production systems are centered on these ways of producing electricity.”

Gordian Raacke, with Renewable Energy Long Island also works on this front. He and his group advocated for and eventually convinced the Long Island Power Authority to do a study on offshore wind power.

“January of this year, LIPA agreed to sign a contract for New York’s first, and the country’s largest, offshore wind project,” he said.

New York Renews hosted a town hall to get community members together to talk about climate change issues. Photo from Ryan Madden

Deepwater Wind will build and operate the 90-megawatt project 30 miles east of Montauk Point in the Atlantic Ocean. The project will generate enough electricity to power 50,000 homes.

In 2012, the group also commissioned a study to evaluate whether Long Island could generate 100 percent of its annual electricity consumption from renewable energy sources. The study, The Long Island Clean Electricity Vision, showed that it would not only be possible, but also economically feasible.

Currently, the LIPC has a campaign to pass the Climate and Community Protection Act in New York State, which would decarbonize all sectors of New York’s economy by 2050, redirect 40 percent of all state funding to disadvantaged communities — which would decrease pollution over decades — and ensure a transition away from fossil fuels.

These topics and others are taught in classes at Stony Brook University under its Sustainability Studies Program. Areas of study include environmental humanities, anthropology, geology, chemistry, economy, environmental policies and planning. Students do hands-on and collaborative work and take on internships in the field. They also clear trails and develop businesses to help increase sustainability among other hands-on initiatives.

“Our mission is to develop students who become leaders in sustainability and help to protect the Earth,” Heidi Hutner, director of the program said. “Climate change and pollution is the most important issue facing us today. We have to find a way to live on this planet and not totally destroy it and all of its creatures. Our students are skilled in many different ways, going into nongovernmental or not-for-profit organizations, becoming law professors, lawyers, journalists, scientists, educators, but all focused on the environment. A former student of ours is the sustainability director at Harvard Medical School.”

Students from the program organized to march in the People’s Climate March in 2014, and will be doing so again April 29. The purpose of the march is to stand up to the Trump administration’s proposed environmental policies.

Students and staff at East Islip High School work with Sustainable Long Island to build a rain garden. Photo from Gabrielle Lindau

Undergraduates in the program also work closely with environmentally active local legislators like state Assemblyman Steve Englebright (D-Setauket), and county Legislators Kara Hahn (D-Setauket) and William “Doc” Spencer (D-Centerport). There is also a Sierra Club on campus.

The LIPC regularly hosts round tables to show other environmental groups what it’s up to and town halls to let community members share their stories and even visit assembly members to lobby for support. Sustainable Long Island, a nonprofit founded in 1998 that specialized in advancing economic development, environmental health and social equality for Long Island, also focuses on low-income communities through its programs.

Food equality and environmental health are the group’s biggest areas of concentration because according to Gabrielle Lindau, the group’s director of communications, the issues are tied to each other.

“There is a polarization here on Long Island,” she said. “We have extremely rich communities, and then we have extremely poor communities.”

According to Lindau, 283,700 people receive emergency food each year, so Sustainable LI builds community gardens and hosts youth-staffed farmers markets to combat the problem.

“It’s a game-changer for low income communities,” she said. “These communities gardens are great because they give people access to fresh, healthy food, and it also puts the power in their hands to find food and also, the learning skills to be able to grow that food. It’s also a paid program, so it’s giving them an opportunity to earn what they’re working toward.”

The youth-staffed farmers markets, which began in 2010, have been a real catalyst for change in communities like Farmingdale, Roosevelt, Freeport, Flanders, New Castle and Wyandanch where access to fresh food is not a given.

Children help Sustainable Long Island build a community garden. Photo from Gabrielle Lindau

“We have so much farming going on out east here on Long Island and I don’t think people who live here ever step back to look at all the food we have here in our own backyard,” Lindau said. “These markets are an incredible program because they’re not only teaching kids in communities about agriculture where they wouldn’t have necessarily had the opportunity to do that, but they’re also teaching them financial literacy skills, and, at the same time, they’re bringing in healthy food items to their neighbors.”

Shameika Hanson a New York community organizer on Long Island for Mothers Out Front, an organization that works to give women a voice for change — empowering and providing them with skills and resources to get decision makers and elected officials to act on their behalf — does specific work with climate change, also calling for the transition from fossil fuels to renewable energy. As a national organization, the topics range depending on the needs of an area from getting methane gas leaks plugged, to stopping oil trains for moving through the area, to getting involved in carbon offsets. Specifically on Long Island, women are creating a task force to ensure the drinking water quality across the island is standardized.

“Democracy doesn’t work without civic engagement,” Hanson said. “There’s a need for a conversation to happen that is united. Even though the water authorities are separate, the water isn’t.”

Sustainable Long Island also works on building rain gardens to reduce stormwater runoff into local waters.

“We’re in a dire situation here on Long Island when it comes to our aquifers,” Lindau said. “We have an intense amount of nitrogen that’s already going into the ground.”

The nonprofit works with the Environmental Resource Management Foundation and PSEG Foundation and builds rain gardens like the one at the Cove Animal Rescue in Glen Cove and others in East Islip and Long Beach.

“It’s about educating communities on the importance of the rain garden and why green infrastructure practices are pivotal for environmental health on Long Island moving forward,” Lindau said. “If we don’t have clean drinking water, we’re going to be in trouble, if we don’t have usable soil to plant in, we’re not going to have farms growing the produce we need to survive and if we don’t have that produce, then we’re not going to be able to bring food into these low-income communities for people who can’t get it otherwise. They’re all connected in a number of different ways and a lot of them root back to health.”

Students in Stony Brook University’s Sustainability Studies Program participate in the 2014 People’s Climate March in NYC. Photo from Heidi Hutner

Sustainable Long Island has done work with local municipalities following superstorms like Hurricane Sandy. They helped communities rebuild, hosted peer-to-peer education meetings to better prepare locals and business owners for another devastating storm and provided job training to bring businesses back.

“A big part of this is going into communities and educating them and helping to advocate in order to facilitate change,” Lindau said. “Working with other groups is extremely important as well. We’re not a lone wolf in the nonprofit world — we not only find it important to work with governments and other municipalities — but to connect with other nonprofits who have something unique to offer as well.”

Melanie Cirillo, with the Peconic Land Trust, reiterated the need for local organizations to team up. The Peconic Land Trust conserves open space like wetlands, woodlands and farmland. It keeps an eye on water quality and infrastructure like Forge River in Mastic, which is a natural sea sponge that absorbs storm surge.

“Wetlands are key in so many of our waterfront properties,” she said. “We have a finite amount of drinking water that we need to protect for our own health. The protection of land is integral to the protection of the water.”

She said although every organization may have a bit of a different focus, they’re all working under the same umbrella and premise, with the same goal in mind: maintaining the health of Long Island.

“I think it’s important for groups to have the ability to bring people together, especially because the impact of climate change affects people in a lot of different ways, whether it’s high energy costs, the impact of superstorms like Hurricane Sandy, sea level rise or coastal erosion, or ocean acidification that impacts people’s fishery and economic way of life,” Madden said. “We have to meet the immediate visceral needs of people — of communities and workers — but we also need to be thinking decades ahead on what it will take to decarbonize our entire economic system. It’s really important for groups to be oriented toward that long term focus, because this is an all hands on deck situation.”

This version corrects the spelling of Stony Brook University’s Sustainability Studies Program Director Heidi Hutner’s last name.

Scientists, like those who work out of the Stony Brook University School of Marine and Atmospheric Sciences’ Marine Sciences Center, are constantly asking questions, as the desire grows to find links between correlation and causation. File photo

Researchers often desire more data to help make the distinction between correlation — it rained the last three Tuesdays — and causation — dumping nitrogen into the lake caused the growth of algae that robbed the lake of oxygen.

Scientists don’t like to get ahead of their information, preferring to take the painstaking steps of going that extra mile to control for as many mitigating or confounding variables as they can.

Researchers are often “reluctant to say with certainty that they are correct,” Larry Swanson, the interim dean of the School of Marine and Atmospheric Sciences at Stony Brook University said.

This hesitation to indicate a certain conclusion can raise challenges for politicians, who would like to rely on scientific proof in developing plans for their constituents.

“Policy people want to create a law or regulation that is definitive and will have the desired outcome,” Swanson added.

File photo.

Since he began working in and around Long Island waters in 1960, he started his work collecting data at wetlands around New Haven, and has since studied hypoxia — the process through which oxygen levels are depleted in waterways.

Swanson urges a more extensive collection of data around Long Island.

“I believe we need to monitor the physical environment for changes not just for time series data, such as temperature, but in order to understand how ecological processes are being altered as a consequence of warming,” Swanson said.

Henry Bokuniewicz, a distinguished service professor of oceanography at Stony Brook, said there was a coastline monitoring program in place in 1995 after nor’easters and hurricanes in 1992, but that the effort petered out.

“This should be re-established if [New York State is] serious about coastal impact of shoreline changes,” he said.

Bokuniewicz also suggests measuring and recording waves that are close to shore, and water levels at the ocean coast and interior bays.

Stony Brook had an initiative for additional hires in a cluster for coastal engineering and management, but never completed the hires for budgetary reasons, Bokuniewicz said. “We could do much better with a new generation of scientists dedicated to the Long Island shore,” he said.

Scientists acknowledge that the study of climate change rarely involves establishing the kind of linear connection between action and reaction that turning up the thermostat in a house would provide.

Scientists distinguish between the weather — is it raining today, tomorrow or next week — and the climate — how does March in New York compare to March in North Carolina?

File photo

The climate, generally, remains consistent with a long-term outlook, even if Long Island might experience an unseasonably hot July, an unusually cool September and a heavier-than-normal snowfall in December.

With climate change, scientists collect as much data as they can to determine how the climate is shifting. That presents significant challenges: how do researchers pick data to feed into their models and the patterns to explore?

The broader trend in March could be that spring starts earlier, extending the growing season and creating opportunities for insects, plants or animals to affect the habitat. That could be slightly different this year, amid a cold snap that lasts more than a few days, or in the wake of an unexpected blizzard days before spring.

Indeed, until, and even after there is a scientific consensus, researchers debate long into the night about their interpretations, conclusions and simulation models.

More often than not, scientists crave more information to help them interpret evolving conditions.

“While we know in general why hypoxia will be bad, we can’t really predict it,” Swanson said. “When will it start? How long will it last? This is because we do not understand all the processes — things like the role of bacteria, phytoplankton and the blooming processes and water circulation.”

Science, as it turns out, is often more about collecting more information to ask better questions and developing more precise theories.

As researchers often point out, they can be wrong for the right reasons and right for the wrong ones, all of which, they hope, helps them understand more about the inevitable next set of questions. And, as scientists have offered, it’s a never-ending discussion, as the best answers lead to more questions.

Colleagues pay tribute to Peter Paul

Paul, second from right, in 2002 with colleagues David Fossan, Linwood Lee, Robert McGrath and Gene Sprouse; and Paul in a family photo. Photo from Gene Sprouse

For nearly 50 years, Setauket’s Peter Paul was a prominent member of the Department of Physics and Astronomy at Stony Brook University. With his death March 11 at the age of 84, the physicist left behind a legacy that will be remembered for years to come, especially by his former colleagues.

A native of Dresden, Germany, Paul received a Ph.D. from the University of Freiburg, and immigrated to the United States when he accepted a postdoctoral position at Stanford University. 

Linwood Lee, emeritus professor, recalled when he recruited Paul in the late 1960s. A former co-worker of Lee’s worked with Paul at Stanford University and told him how impressive the physicist was. Lee knew he had to hire him during a time when he called coming to Stony Brook University “an adventure” because the school was in its infancy.

Peter Paul. Photo from Stony Brook University

Lee said Paul was marvelous, and he’s grateful he recruited the professor.

“We established a laboratory here, and from the moment he got here, he was the driving force to make us all do better,” Lee said.

Paul was a professor at the university from 1967 to 2015 and later a distinguished service professor in the department and served as chairman twice during his tenure. One of Paul’s greatest achievements was building a first-class nuclear physics group along with his colleagues at Stony Brook.

In 1973, when the physicist spearheaded a small group to develop, design and construct Stony Brook’s superconducting linear for heavy ions, an improvement of the university’s existing Van de Graaff accelerator, it became the first such machine at a university lab.

Gene Sprouse, now a distinguished John S. Toll professor at SBU, was a graduate student at Stanford University when he met Paul. He later came to Stony Brook and worked on the accelerator project with him.

“That machine was really unique. It was a very powerful accelerator at a university,” Sprouse said.

Paul Grannis, another of Paul’s colleagues at SBU, said Paul was very proud of the accelerator project.

“It enabled research that had previously not been possible to be done, and it was quite a unique facility in the country,” Grannis said. “I know Peter was very proud of that and considered it one of his major achievements.”

Paul became a member of the Nuclear Science Advisory Committee in 1980, and as chair, led the development of the 1998 Nuclear Science Long Range Plan, which in turn led to the construction of the Relativistic Heavy Ion Collider at Brookhaven National Laboratory.

Paul was appointed deputy director for science and technology in 1998 at BNL, and when John Marburger was appointed as President George W. Bush’s scientific advisor in 2001, Paul stepped in as interim director at the laboratory until 2003. Under Paul’s direction, BNL made many advances, including starting the construction of Brookhaven’s Center for Functional Nanomaterials, and conceptualizing the electron-ion collider as a successor to RHIC.

Peter Paul with Stony Brook University President Samuel L. Stanley, M.D. Photo from Stony Brook University

Paul returned to SBU after serving as interim director at BNL, and his ongoing success was never a surprise to those who knew him.

“Peter was very energetic and driven,” Sprouse said. “He was always pushing for excellence.”

Sprouse described Paul as a visionary who helped to create the Stony Brook University people know today, especially the Department of Physics and Astronomy.

“Throughout his career he helped to build the nuclear physics groups at Stony Brook, he helped to build the department, and then he helped to build things at Brookhaven,” Sprouse said. “He always kept an eye out for putting in place instruments and institutes that could strengthen Stony Brook in particular and Brookhaven, too.”

Grannis echoed Sprouse’s praise of Paul.

“He was very motivated to do the best that he could in all of his scientific endeavors and to insist that all those who worked with him do so,” Grannis said.

Chang Kee Jung, a SUNY distinguished professor, said when Paul returned to Stony Brook after his time at BNL, he looked for a research program to be involved in. He said he was surprised when Paul knocked on his office door one day and told him he was interested in the projects he was working on at the time.

Jung said he was hesitant at first due to Paul’s extensive experience. However, Paul assured him he would never do anything to interfere. Jung said Paul was always curious to learn more in his field, and didn’t have an ego despite all of his successes. The professor said Paul was the perfect person to have on his team, and he became an advisor to Jung. The two worked together until Paul became the university’s associate vice president for Brookhaven affairs — a position he held until his retirement in 2015.

He also remembers Paul fondly on a personal level and said he was grateful for the opportunity to visit the professor at home a couple of weeks before his death.

“Among all the people I met at Stony Brook, he was the strongest supporter of me, personally,” Jung said. “For whatever reason he liked me and the projects I was doing.”

Lee added that like many professors, Paul was always proud of his students. Many left SBU for prestigious careers, including Michael Thoennessen, chair, APS division of nuclear physics at Michigan University. Thoennessen wrote in an email Paul was his Ph.D. adviser when he attended SBU in the late 1980s.

Peter Paul. Photo from Bryant Funeral Home

“In Germany the Ph.D. adviser is called the ‘Doktor Vater’ (Ph.D. Father) and that is exactly what Peter was to his students,” Thoennessen wrote. “In addition to being a brilliant scientist and a great administrator, Peter was an amazing mentor. I would not be where I am right now without Peter’s advice and guidance.”

Grannis added that despite a demanding career, Paul led a well-rounded life.

“He had a very broad range of interests not only in science but in music, in travel, in reading,” Grannis said. “He was very well-informed on many things.”

Paul was an ardent opera-goer and hiker, and Jung remembers the professor being in his 70s and still traveling upstate to go skiing. His career provided him the opportunity to travel extensively, too. Among his trips were vacations to his homeland of Germany.

In his lifetime, Paul received numerous awards including the American Physical Society Fellow, Institute of Physics Fellow, Sloane Research Fellow, Alexander von Humboldt Senior Scientist Award and the Order of Merit First Class from the German government. Paul is also an inductee in the Long Island Technology Hall of Fame. However, his greatest honor may be the legacy he leaves behind at Stony Brook University.

“Peter was one of the people that made us a better university,” Lee said. “He was active in associating us with Brookhaven, and he was always a booster of the university, and we always boosted Peter. It was hard to keep him because he was recognized as a top scientist. He turned down some very good offers to stay here.”

Sprouse said Paul inspired many to come to SBU and helped them, with his encouragement and leadership, to develop their careers.

“I just think that he was somebody that was really dedicated to the university and wanted to build it,” he said. “For those of us who were at Stony Brook, 40, 50 years ago, Stony Brook was kind of a dream, and Peter really made it a reality.”

Stony Brook softball player Danni Kemp died after a battle with cancer. Photo from SBU

The Stony Brook family is mourning the loss of student-athlete Danni Kemp, who passed away on the morning of March 10 surrounded by family following her battle with cancer.

The Seawolves, who had dedicated their softball season to the sophomore, 19, postponed March 10 games against Santa Clara and New Mexico in Albuquerque, New Mexico.

Danni Kemp up to bat for the Seawolves. Photo from SBU

“Our hearts are heavy today and our love goes out to Danni and her family,” Stony Brook softball coach Megan Bryant said. “In all too short of a young life, Danni touched so many in a beautiful way. She fought so hard against this terrible disease, and showed us what true courage is. May Danni only know peace now.”

In July, Kemp was hit in the head by a pitch while playing in a summer league game. When she began feeling dizzy, had trouble focusing and couldn’t keep her balance, doctors tested her for a concussion. An MRI revealed a cancerous brain tumor.

Due to the location, surgery was not an option, and Kemp began radiation therapy Aug. 29, receiving treatment Monday through Friday for a total of six weeks.

A GoFundMe page was created on behalf of the family Aug. 22, and in six months had raised nearly $130,000 of the $150,000 goal, with donations from 1,575 people.

“Danni is the toughest young woman we have all ever met,” wrote Bradley Taylor, who created the GoFundMe page. “Her strong and indomitable will has already proven to be more than enough to battle and beat a rare kidney disease while she was in high school. This will be a battle, but with so many people who know and love Danni and her family, they’ve got an army behind them.”

Since her death, hundreds more dollars have poured in from those touched by the loss of Kemp, even those who didn’t know her.

“I felt very sad when I read the story,” wrote John Colombo.

Janis Matton was also saddened upon hearing the news.

“I am so very sorry for your loss,” she wrote. “Danni was truly an inspiration to all. Prayers for your family.”

“We got an angel in the outfield behind us. Heavy hearts with a little something more to play for this season.”

—Kevin Kernan

Kemp hit .446 as a junior for J.A. Foran High School in Connecticut en route to All-Conference and first team All-State honors. In her first three seasons at Foran, she collected more than 100 hits and 40 stolen bases. She was also a member of the Connecticut Charmers, an Under-18 fast pitch showcase team coached by Neil Swanchak.

As a Seawolf, she scored her first career hit against Charlotte University Feb. 20 of last year; had a double and scored a run at Florida Atlantic University Feb. 26; had two hits, including a bases-clearing double in a win over Columbia University Feb. 27; walked twice and drove in a run at Manhattan College March 30; drew three walks in another contest; and walked and scored a run at the University of Massachusetts Lowell April 16.

Kemp’s death had an impact that reverberated beyond just her softball family. After news of her death spread around campus, many student-athletes took to social media.

Tiffany Zullo, a midfielder on the women’s lacrosse team from Connetquot High School, tweeted: “We all play for Danni and will forever be Danni Strong. Rest in peace to a beautiful soul.”

Kevin Kernan, a baseball pitcher, posted, “We got an angel in the outfield behind us. Heavy hearts with a little something more to play for this season.”

Details for services will be forthcoming once the Kemp family makes arrangements.

“Danni had her entire life in front of her,” Stony Brook athletic director Shawn Heilbron said. “I am devastated beyond words and heartbroken for her family and everyone who loved her. Her valiant fight over the past several months was an inspiration to all of us, and her impact on the Stony Brook Athletics family will be felt for many years to come.”

Miller Place art teacher Julia Vogelle helped form The Brick Studio and Gallery nonprofit. Photo from Julia Vogelle

Who better to bring vibrancy and revitalization to downtown Rocky Point than a group of local artists? With the support of elected officials, a new nonprofit organization is leading the charge to help enrich, educate and electrify the Rocky Point community and surrounding areas.

The Brick Studio and Gallery is an art collective of more than 20 local artists and instructors with aspirations to grow and develop into a full-fledged community studio and hub.

Spearheaded by Miller Place High School art teacher Julia Vogelle and professional ceramicist Justine Moody, the group blossomed around the time Stony Brook University’s Craft Center and ceramics studio closed for renovations in January 2016, leaving potters and artists without a space to do what they love.

Pottery making will be offered at The Brick Studio and Gallery. Photo from Julia Vogelle

Vogelle and Moody, who shared dreams of opening up a cooperative to bring art back into the community, met in the wake of the Craft Center shutdown and enlisted the help of the “homeless” artists to form the organization.

Since then, the project has grown, culminating in a Kickstarter campaign with an ambitious goal of $18,000 to turn a dream into a reality. With 120 backers, their goal has already been exceeded, raising a total of $18,150.

The money will cover the start-up costs to find a location and equip and supply the studio with 14 pottery wheels, two electric kilns, kiln shelves, clay, glazes and ceramic tools. According to the fundraiser page, the studio “has the potential to begin a renaissance in historic Rocky Point, with other artists and artisans joining in bringing life to other empty buildings” and plans to open in early spring.

“My vision is to have this cultural center energize and bring all the money back into the hamlet,” Vogelle said. “Rocky Point has a lot to offer. People 16 and up can come; we’d have services for students, seniors, veterans and anyone who would like to work. I want to look at Broadway in Rocky Point as ‘artist’s row.’”

In addition to pottery, glass and jewelry making, the studio will be a venue for documentary showings, live poetry, trivia nights and  live music.

Moody expanded on the grand vision.

“I think it’s going to become a destination place … I don’t know that Rocky Point has one, and there are a lot of towns here with a tremendous group of creatives who don’t really have a place to call their own,” Moody said.

She’s hoping it could be a place to attract locals during the summer to take lessons, and others from outside the community on Friday nights, saying she envisions big events on weekends and other pop-up events throughout the year.

Suffolk County Legislator Sarah Anker (D-Mount Sinai) believes The Brick has the potential to be a tourist attraction that could boost Rocky Point’s foot traffic and revenue — much-needed since the state built the bypass, which encourages traffic to go around the area, hitting downtown businesses especially hard.

“There are a lot of towns here with a tremendous group of creatives who don’t really have a place to call their own.”

— Justine Moody

“So many of our residents come in from the Long Island Expressway, from Sunrise Highway, and they look to go east from the North Fork, and my hope is that maybe they’ll turn left and go west to experience what Rocky Point and Shoreham have to offer,” Anker said. “There are so many high-level artists that live in the area and this will hopefully give them a way to stay local and promote their craft to the public.”

Anker has been involved in North Shore revitalization plans since 2011, participating with the Rails to Trails project and the clean-up of the Tesla Science Center at Wardenclyffe, and said that art is not just trendy.

“We underestimate how important art is, it needs to be cultivated,” she said. “It’s part of our culture and it has an educational component. It will definitely benefit downtown Rocky Point.”

Councilwoman Jane Bonner (C-Rocky Point), who contributed $100 to the art collective’s Kickstarter campaign, said she’s so excited about the studio and points to Vogelle and Moody’s hard work and dedication.

“They’re very dedicated and committed and they’re not looking for somebody else to solve their problem … grass isn’t growing under feet at all and it’s hard not to pay attention to that,” Bonner said.

As a 30-year Rocky Point resident, the councilwoman is hopeful that the artists can bring people back to downtown Rocky Point and trigger change.

Vogelle feels the same, stating that she believed that the art can bring value to homes and surrounding businesses.

“If you put art into a community, people want to move in,” she said. “If you put music in town, people want to gather around and enjoy it. A cultural center like this always connects with schools in the district and it will also help people realize there’s so much culture that’s hidden. And anyone can get hooked on ceramics — the elderly, veterans, teens. Once you touch mud, you never go back.”

Joseph Schwartz, right, with a collaborator, Daichi Shimbo, the director of the Translational Lab at the Center for Behavioral Cardiovascular Health at Columbia University Medical Center, in front of a poster they presented at an annual meeting of the American Society of Hypertension in New York City in 2013.Photo by John Booth, III

By Daniel Dunaief

The cardiovascular skies may be clear and sunny, but there could also be a storm lurking behind them. About one in eight people who get a normal reading for their blood pressure have what’s called masked hypertension.

That’s the finding in a recent study published in the American Journal of Epidemiology led by Joseph Schwartz, a professor of psychiatry and sociology at Stony Brook University and a lecturer of medicine at the Columbia University Medical Center. Schwartz said his research suggests that some people may need closer monitoring to pick up the kinds of warning signs that might lead to serious conditions.

“The literature clearly shows that those with masked hypertension are more likely to have subclinical disease and are at an increased risk of a future heart attack or stroke,” Schwartz explained in an email.

Tyla Yurgel, Schwartz’s lab manager from 2005 to 2016 who is now working in the Department of Psychiatry, wears the ambulatory blood pressure cuff that was a part of the study. Photo by Arthur Stone

Schwartz and his colleagues measured ambulatory blood pressure, in which test subjects wore a device that records blood pressure about every half hour, collecting a set of readings as a person goes about the ordinary tasks involved in his or her life. Through this reading, he was able, with some statistical monitoring, to determine that about 17 million Americans have masked hypertension, a term he coined in 2002.

Schwartz, who started studying ambulatory blood pressure in the late 1980s, has been actively exploring masked hypertension for over a decade. Ambulatory blood pressure monitoring is more effective at predicting subclinical disease such as left ventricular hypertrophy and the risk of future cardiovascular events, said Schwartz. “There was some rapidly growing evidence it was a better predictor of who would have a heart attack or stroke than in the clinic, even when the blood pressure in the clinic was properly measured,” he said.

To be sure, the expense of 24-hour monitoring of ambulatory blood pressure for everyone is unwieldy and unrealistic, Schwartz said. The list price for having an ambulatory blood pressure recording is $200 to $400, he said. Wearing the device is also a nuisance, which most people wouldn’t accept unless it was likely to be clinically useful or, as he suggested, they were paid as a research participant.

Schwartz said he used a model similar to one an economist might employ. Economists, he said, develop simulation models all the time. He said over 900 people visited the clinic three times as a part of the study. The researchers took three blood pressure readings at each visit. The average of those readings was more reliable than a single reading.

The study participants then provided 30 to 40 blood pressure readings in a day and averaged those numbers. He collected separate data for periods when people were awake or asleep. A patient close to the line for hypertension in the clinical setting was the most likely to cross the boundaries that define hypertension. “You don’t have that far to go to cross that boundary,” Schwartz said.

After analyzing the information, he came up with a rate of about 12.3 percent for masked hypertension of those with a normal clinic blood pressure. The rate was even higher, at 15.7 percent, when the researchers used an average of the nine readings taken during the patient’s first three study visits.

William White, a professor of medicine at the Calhoun Cardiology Center at the University of Connecticut School of Medicine in Farmington was a reviewer for one of these major studies. “They are excellent,” said White, who has known Schwartz for about a decade. “We should be monitoring blood pressure more outside of the clinical environment.”

Indeed, patients have become increasingly interested in checking their blood pressure outside of the doctor’s offices. “We have a 200 to 300 percent increase in requests for ambulatory blood pressure monitoring from our clinical lab during the last five to ten years — in all age groups, genders and ethnicities,” explained White.

The challenge, however, is that tracking hypertension closely for every possible patient is difficult clinically and financially. “There are no obvious clinical markers for masked hypertension other than unexpectedly high self-blood pressure or unexplained hypertensive target organ damage,” White added.

Schwartz himself has a family history that includes cardiovascular challenges. His father, Richard Schwartz, who conducted nonmedical research, has a long history of cardiovascular disease and had a heart attack at the age of 53. His grandfather had a fatal heart attack at the same age. When Schwartz reached 53, he said he had “second thoughts,” and wanted to get through that year without having a heart attack. He’s monitoring his own health carefully and is the first one in his family to take blood pressure medication.

Schwartz, who grew up in Ithaca, New York, came to Stony Brook University in 1987. He called his upbringing a “nonstressful place to grow up.” He now lives in East Setauket with his wife Madeline Taylor, who is a retired school teacher from the Middle Country school district. The couple has two children. Lia lives in Westchester and works at Graham Windham School and Jeremy lives in Chelsea and works for Credit Suisse.

As for his work, Schwartz said the current study on masked hypertension was a part of a broader effort to categorize and understand pre-clinical indications of heart problems and to track the development of hypertension.

Now that he has an estimate of how many people might have masked hypertension, he plans to explore the data further. That analysis will examine whether having masked hypertension puts a patient at risk of having cardiovascular disease or other circulatory challenges. “We are very interested in whether certain personality characteristics and/or circumstances (stressful work situation) makes it more likely that one will have masked hypertension,” he explained.