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An electroencephalogram (EEG) study of adolescents with autism spectrum disorder (ASD) identified a neural signal that may help explain the variation of how those with ASD perceive or understand the mental states of others (called “Theory of Mind”). Led by Matthew Lerner, PhD, of Stony Brook University, the study is published in Clinical Psychological Science.

While challenges with Theory of Mind have long been associated with ASD, it is now known that many people with ASD do not struggle with his sort of perspective-taking. For example, those with increased autism symptoms do not necessarily exhibit increased deficits in the understanding others socially, and vice versa. However, this variability in Theory of Mind is not well understood.

A total of 78 adolescents ages 11 to 17 participated in the study, most with ASD. With the EEG in place, the participants viewed Theory of Mind vignettes of social scenes and made mental state inferences on the characters’ behavior as their brain activity was recorded.

“We know the brains of those with ASD process social experiences differently, yet little work has linked these differences directly to Theory of Mind,” says Lerner, Associate Professor of Psychology, Psychiatry & Pediatrics in the Department of Psychology at Stony Brook. “In our study, we first identified an electrical brain-based marker that relates to Theory of Mind ability in typically-developing teens, and found that it does so in ASD, too. This marker, called the Late Positive Complex (LPC), seems to reflect one’s ability to hold and reflect an idea or situation in one’s mind.”

Lerner and his team found that LPC scores in ASD adolescents related to better Theory of Mind accuracy and fewer ASD symptoms. More importantly, The LPC statistically explained the relationship between ASD symptoms and Theory of Mind accuracy, suggesting that this EEG signal may explain why some individuals with ASD struggle with Theory of Mind.

“Essentially, if this marker is present in someone with ASD, they do not seem to have trouble with Theory of Mind, but if it is absent they do.”

The authors point out that evidence from the EEG study suggests that deficits in Theory of Mind reasoning in those with ASD occur relatively early in the brain process of perception, and stem from difficulties holding an idea or image in mind when it is no longer visible.

They conclude that “the current findings increase understanding of the neural mechanisms implicated in social-cognitive functioning in ASD and further inform clinical practice, research and theory involving social cognition in ASD.”

 

Coming Home

By Ellen Mason, Stony Brook

 

The view from my window,

Looking out to the street,

Brings anticipation

Of deliveries complete. 

 

From FedEx or postman

And sellers on eBay,

I await these small boxes

And how little they all weigh. 

 

My mission accomplished

Might seem foolish to some,

But I’m filled with delight

By these parcels that come. 

 

On eBay I found it,

And made it my mission:

To replace my old dollhouse, 

Furnished bedroom to kitchen. 

 

In primary colors

And precisely scaled detail,

This house from the fifties

Revives memories that were stale. 

 

A complete living room,

Molded from plastic,

With couch and TV.

Just so fantastic!

 

A sewing machine,

A phone and a vacuum,

Have movable parts,

Like commode in the bathroom. 

 

The biggest surprise

In daytime or night,

Is the Disney themed nursery,

Much to my delight.

 

Lithographed on the walls

And the yellow tin floor,

Are drawings of Mickey

And Donald and more. 

 

A two-car garage

And second floor terrace

Complete the good life for

A suburban heiress. 

 

I now have before me

My childhood dream,

Resurrected once more. 

I give thanks to the team

 

Of sellers on eBay,

Of which there are many,

Who sell vintage stuff. 

This was worth every penny. 

 

If nostalgia now calls you

Then, at my behest,

Perhaps you will tune

Into “Father Knows Best.

 

Dollhouse from the Marx Toy Company, accessories from Marx and Renwal.

 

Photo by Tom Caruso

BLAZE OF GLORY

Tom Caruso of Smithtown snapped this beautiful photo during a walk in Stony Brook Village on June 16. He writes, ‘My wife and I were walking down the road leading to the water when I saw these Orange Daylilies blazing in the light of the setting sun. I shot this image with my cell phone and was amazed at the contrast between the flowers and their surroundings.

Send your Photo of the Week to [email protected]

 

Photo from Heckscher Museum

The Heckscher Museum of Art, 2 Prime Ave., Huntington invites children ages 5 to 10 to stop by the museum on Thursdays from July 8 to Aug. 12 to take part in their Drop In & Create program from 11 to 11:30 a.m.

Create fun works of art in a variety of materials inspired by artwork in the Museum’s Collection! Each week’s project will be exciting and different! Held outside on the Museum Terrace, this program is weather-permitting. In the case of inclement weather, the program will be held the following day. Families are invited to come into the Museum following the program at 11:30 am to explore the galleries!

Fee is $10 per child, adults free payable at the door. No registration necessary.
Fee includes all art supplies and general admission to the museum from 11:30  to noon.

Rain dates are Fridays, July 9 to Aug. 13.

For more information, call 631-380-3230 or visit www.heckscher.org.

Above, microscopic image showing brown, antibody-based staining of keratin 17 (K17) in bladder cancer. Image from Shroyer Lab, Stony Brook University

By Daniel Dunaief

Detectives often look for the smallest clue that links a culprit to a crime. A fingerprint on the frame of a stolen Picasso painting, a shoe print from a outside a window of a house that was robbed or a blood sample can provide the kind of forensic evidence that helps police and, eventually, district attorneys track and convict criminals.

Kenneth Shroyer MD, PhD                  Photo from SBU

The same process holds true in the world of disease detection. Researchers hope to use small and, ideally, noninvasive clues that will provide a diagnosis, enabling scientists and doctors to link symptoms to the molecular markers of a disease and, ultimately, to an effective remedy for these culprits that rob families of precious time with their relatives.

For years, Ken Shroyer, the Marvin Kuschner Professor and Chair of Pathology at the Renaissance School of Medicine at Stony Brook University, has been working with a protein called keratin 17.

A part of embryological development, keratin 17 was, at first, like a witness who appeared at the scene of one crime after another. The presence of this specific protein, which is unusual in adults, appeared to be something of a fluke.

Until it wasn’t.

Shroyer and a former member of his lab, Luisa Escobar-Hoyos, who is now an Assistant Professor at Yale, recently published two papers that build on their previous work with this protein. One paper, which was published in Cancer Cytopathology, links the protein to pancreatic cancer. The other, published in the American Journal of Clinical Pathology, provides a potentially easier way to diagnose bladder cancer, or urothelial carcinoma.

Each paper suggests that, like an abundance of suspicious fingerprints at the crime scene, the presence of keratin 17 can, and likely does, have diagnostic relevance.

Pancreatic cancer

A particularly nettlesome disease, pancreatic cancer, which researchers at Stony Brook and Cold Spring Harbor Laboratory, including CSHL Cancer Center Director David Tuveson, have been studying for years, has a poor prognosis upon diagnosis.

During a process called surgical resection, doctors have been able to determine the virulence of pancreatic cancer by looking at a larger number of cells.

Shroyer and Escobar Hoyos, however, used a needle biopsy, in which they took considerably fewer cells, to see whether they could develop a k17 score that would correlate with the most aggressive subtype of the cancer.

“We took cases that had been evaluated by needle biopsy and then had a subsequent surgical resection to compare the two results,” Shroyer said. They were able to show that the “needle biopsy specimens gave results that were as useful as working with the whole tumor in predicting the survival of the patient.”

A needle biopsy, with a k17 score that reflects the virulence of cancer, could be especially helpful with those cancers for which a patient is not a candidate for a surgical resection.“That makes this type of analysis available to any patient with a diagnosis of pancreatic cancer, rather than limiting it to the small subset of cases that are able to undergo surgery,” Shroyer said. 

Ultimately, however, a k17 score is not the goal for the chairman of the pathology department.

Indeed, Shroyer would like to use that score as a biomarker that could differentiate patient subtypes, enabling doctors to determine a therapy that would prove most reliable for different groups of people battling pancreatic cancer.

The recently published report establishes the foundation of whether it’s possible to detect and get meaningful conclusions from a needle biopsy in terms of treatment options.

At this point, Shroyer isn’t sure whether these results increase the potential clinical benefit of a needle biopsy.

“Although this paper supports that hypothesis, we are not prepared yet to use k17 to guide clinical decision making,” Shroyer said.

Bladder cancer

Each year, doctors and hospitals diagnose about 81,000 cases of bladder cancer in the United States. The detection of this cancer can be difficult and expensive and often includes an invasive procedure.

Shroyer, however, developed a k17 protein test that is designed to provide a reliable diagnostic marker that labs can get from a urine sample, which is often part of an annual physical exam.

The problem with bladder cancer cytopathology is that the sensitivity and specificity aren’t high enough. Cells sometimes appear suggestive or indeterminate when the patient doesn’t have cancer.

“There has been interest in finding biomarkers to improve diagnostic accuracy,” Shroyer said. 

Shroyer applied for patent protection for a k17 assay he developed through the Stony Brook Technology Transfer office and is working with KDx Diagnostics. The work builds on “previous observations that k17 detects bladder cancer in biopsies,” Shroyer said. He reported a “high level of sensitivity and specificity” that went beyond that with other biomarkers.

Indeed, in urine tests of 36 cases confirmed by biopsy, 35 showed elevated levels of the protein.

KDx, a start up biotechnology company that has a license with The Research Foundation for The State University of New York, is developing the test commercially.

The Food and Drug Administration gave KDx a breakthrough device designation for its assay test for k17.

Additionally, such a test could reveal whether bladder cancer that appears to be in remission may have recurred.

This type of test could help doctors with the initial diagnosis and with follow up efforts, Shroyer said.“Do patients have bladder cancer, yes or no?” he asked. “The tools are not entirely accurate. We want to be able to give a more accurate answer to that pretty simple question.”

A scene from 'Breaking Boundaries'. Photo from Netflix

Reviewed by Jeffrey Sanzel

Netflix’s Breaking Boundaries: The Science of Our Planet explores the idea that humanity has pushed the planet beyond survival and sustainability. While ably hosted by the ever-reliable Sir David Attenborough, the dominant voice is Swedish Professor Johan Rockström, an informed and articulate scientist with a range of facts and concepts that he introduces over the one hour and fifteen-minute running time.

Swedish Professor Johan Rockström

There are few topics — if any — more important than the future of Earth. And while some make claims against it, climate change, global warming, and other man-driven destructions are real and present dangers, ones that seem to be growing geometrically. This documentary attempts to explain these issues by setting down a theory of boundaries. It then proceeds to explain how they are being crossed.

Breaking Boundaries opens with a discussion of the stability of Earth’s temperature and climate for 10,000 years; this allowed for the development of the modern world. The documentary then proceeds to cite examples of our destructive behaviors and how they have negatively impacted various ecosystems, including the Amazon, the Great Barrier Reef, etc. Rockström’s refrain is, “It is not about the planet. It is about us. About our future.” Perhaps he is trying to appeal to our self-centered nature rather than our desire to correct what we have broken. Unfortunately, his slightly skewed sense of humanity is probably well-founded.

The film starts with a glimmer of hope, but five minutes in, the bad news is announced: over the past fifty years, we have pushed ourselves out of the norm that existed the previous 10,000 years. And there may be no fix for this situation. 

Over the next fifty minutes, a disjointed narrative attempts to explain the nine planetary boundaries — the distance from the safe zone to the danger zone to the high risk/critical zone. Carbon dioxide in the atmosphere has caused droughts, heatwaves, forest fires, and flooding. Ocean acidification, the dangers of aerosols, and novel entities of human pollution are just some of the ideas introduced. Thus, there is an immediate need not just to reduce but to fossil-free within three decades.

‘Breaking Boundaries’. Photo from Netflix

Scientists meditate on the destruction of the icecaps, evaluate the reduction of flora and fauna to the point of extinction, and offer a great number of numbers that sometimes seem like … a great number of numbers. (Overwhelming statistics and an extraordinary list of theories make for a bit of confusion.) Finally, the film circles back to the four boundaries that have been crossed and possibly irrevocably (but maybe not?): climate, forest loss, nutrients, and biodiversity.

Every bit of this is important information. But the problem comes down to this: Breaking Boundaries is a documentary dealing with a life-and-death topic in a clumsy and wrong-headed approach. Director Jonathan Clay has underestimated his audience, deciding that an MTV assault is the only way to connect. As a result, the bells and whistles drown out the material. Yes, they are alarm bells and fire whistles, but this is an onslaught, not an explanation. 

One talking head goes so far as to refer to the “Mad Max future.” A drinking game based on the repetition of “tipping point” and “irreversible” would put the players out in under twenty minutes. There is probably truth in every statement and comment. But judicious editing would have allowed for a variety of tactics, rather than what comes across as a relentless, one-note attack. 

The effects are overwhelming and non-stop, with even the most sedate moments backgrounded with a strange light show. (Was this Mr. Clay’s first time with a green screen?) The graphics seem to be inspired by the 1980s’ Tron. Or perhaps Saturday Night Fever. Everything explodes on screen, making for restless, jittery filmmaking. The result wholly lessens the film’s integrity.

Many moments succeed in capturing the beauty of nature. If a bit generic, they serve as a strong reminder of what is being destroyed. Some disturbing images are not sensational but instead are telling: wild animals who now live close to settled and “civilized” areas are shown in droves on highways and the environs of cities. While we are always warned not to anthropomorphize, there is a palpable fear in their eyes.

‘Breaking Boundaries’. Photo from Netflix

There are two moments of resonating humanity. First, a scientist discussing the bleaching of the Great Barrier Reef becomes choked up, clearly a spontaneous and honest reaction to what he has seen. Second, a conservationist revisits one of the sites where she had studied birds before its incineration. The destruction of fifty million acres of Australian land caused the displacement or death of an estimated three billion animals. While she looks at the bleak landscape, she says, “This is an ecological catastrophe.” But this is also highly personal and, again, powerful in its simplicity. 

If only the director had trusted moments like these. Instead, he chose window dressing that makes the experience a late-night infomercial for the predictions of Nostradamus.

After fifty-nine minutes of apocalyptic prognostication, there are twelve minutes of “but-it-can-all-be-saved.” We need to bend the global curve of emissions, cutting 6 to 7% per year. We can draw down the carbon by planting more trees. Changing our diets to healthy foods will contribute to the saving of the planet. We can eliminate waste by turning the linear cycle into a circular one by recovering raw materials (and benefit the economy). Finally, we must turn towards renewable energy. “The window is still open.” Rockström believes that 2020 to 2030 is the decisive decade: what happens in these ten years will determine what happens over the coming centuries.

Perhaps there is no longer a way to make people listen — and more importantly, take action — without being sensationalist. However, this film will win no converts and will probably not engage the already aware and committed. The call is to act as “earth’s conscience — it’s brain — thinking and acting with one unified purpose — to ensure that our planet forever remains healthy and resilient — the perfect home.” It is not just a noble purpose but an essential one. There have been, and there will be many valuable examinations of this subject matter. Unfortunately, in the end, Breaking Boundaries is not one of them.

Legislator Nick Caracappa with Dr. Karen J. Lessler, President of the Middle Country Central School District’s Board of Education

At a recent Board of Education meeting for the Middle Country Central School District, Suffolk County Legislator Nick Caracappa was recognized and awarded with a Certificate of Appreciation.

The certificate was the Board of Ed’s way of thanking the Legislator for his efforts in successfully eliminating Stagecoach Elementary School in Selden as a polling location for general and special elections. Caracappa, a former Middle Country School Board member himself is currently in negotiations with the Suffolk County Board of Elections to eliminate polling locations from other schools in the district as well.

“Thank you Legislative Caracappa for following through on protecting our students by removing the voting from Stagecoach Elementary.  We certainly appreciate the partnership,” stated Middle Country School’s Board of Ed. President, Dr. Karen J. Lessler. Superintendent Dr. Roberta Gerold commented, “Middle Country thanks Legislator Caracappa for his commitment to the safety and security of our district – we appreciate him!”

“Our children’s safety is the number one priority in these efforts,” stated Legislator Caracappa. “I acted on this measure not only as an elected official, but as a father. I am humbled by the recognition for what was truly a community effort. My thanks go out to the Selden Fire Department, along with Brookhaven Town Supervisor Ed Romaine for providing alternate polling sites for voters. Additionally, I thank Dr. Lessler, Dr. Gerold, and the entire Board of Education for acknowledging me with this Certificate of Appreciation.”

Photo courtesy of Allied Foundation

Just before Father’s Day, the Allied Foundation Diaper Bank, headquartered in Melville,  held a special event at Flexible Systems in Hauppauge,  marking the collection, purchase and distribution of 1 million diapers to impact the lives of 40,000 low-income families across Long Island and regionally since the start of the COVID-19 pandemic.

“Reaching this extraordinary milestone and impacting the lives of so many families in need could not have been achieved without the help of our partners,” said Allied Foundation Executive Director Heather Edwards. “The diapers and supplies collected over the past year provide much-needed relief to young families across the New York regions and Long Island who are struggling with the need for diapers. More parents are facing this strain and are simply unable to afford them due to loss of employment or other hardship caused by the COVID-19 pandemic.”

The Allied Foundation collects packages of diapers and distributes them throughout Nassau, Suffolk, and Queens counties via 50 Agency Partners including Momma’s House, The Safe Center of Long Island, SCO Family of Services, St. Vincent de Paul of Long Island, WIC Programs in Brentwood, Riverhead, Stony Brook Wyandanch, The Association for Mental Health and Wellness, Family Service League, North Fork Spanish Apostolate, The Butterfly Effect Project and The INN among others.

During the past 12 months, donations have come in from the Long Island Community Foundation, The Claire Friedlander Family Foundation, SAR Family Fund, Yurman Family Fund, Robin Hood, All For The East End, Help Me Grow – Long Island, The JPB Foundation, Connecticut Children’s Medical Center, Docs for Tots, and Girl Scouts of Jericho-Syosset, Lower School at Friends Academy among others. The diapers will be distributed locally through the Allied Foundation Diaper Bank.

Even before the COVID-19 crisis, approximately one in three U.S. families experienced diaper need, a public health issue exacerbated by the growing economic and unemployment crisis caused by the pandemic.

“Diapers are a basic need no baby should ever have to go without. Babies and children in low-income families across Long Island are at greatest risk of suffering the effects of diaper need because many families simply cannot afford diapers. There are no state or federal child safety-net programs allocating dollars specifically for the purchase of diapers; however, thanks to the Allied Foundation Diaper Bank and the donations from our partners, friends and allies, diapers are able to get into the hands of financially strained families who need them most,” explained Scott Svitek, MD, Chair, Allied Foundation Board and Partner, Allied Physicians Group.

“Diapers are needed by many families who struggle to afford enough diapers to keep their babies clean, dry and healthy. This results with diapers being re-used or left on for longer periods of time that leave babies susceptible to painful rashes and infection that can ultimately lead to poor health outcomes. Clean, dry diapers are critical for ensuring good health and well-being for babies and their families,” said added Edwards.

Infants require up to 12 diapers a day and toddlers need about eight, making the cost as much as $80 per month, per child. The Allied Foundation Diaper Bank fills an important void in getting diapers to people facing financial struggles who cannot buy them when there are currently no programs that provide for this. Prices for diapers are forecasted to increase 10 percent or more in the coming months, making it more challenging for families.

Pictured from left to right at the celebration marking this milestone event are: Marty Schmitt, Partner with Flexible Systems (Donor to Allied Foundation), which donates Warehouse Space for Allied Foundation Diaper Bank; New York State Assemblywoman Kimberly Jean-Pierre (District 11); Kerry Fierstein, MD, CEO of Allied Physicians Group and Adjuvant.Health; Allied Foundation Board of Directors Executive Director Heather Edwards; Grecia Morea, Local Mother and recipient of 1 millionth diaper; Scott Svitek, MD, Chair of Allied Foundation Board of Directors; Jeannie DeMaio, representing the Long Island Community Foundation (Donor to Allied Foundation); Noel Raab, President, Five Star Advertising, Long Island Imagine Awards Committee Member (Donor to Allied Foundation); and Tommy DiMisa, Vanguard Insurance Agency, Long Island Imagine Awards Committee Member, Philanthropy in Phocus  (Donor to Allied Foundation) who is holding child Ian Morea (second to last from right).

The Allied Foundation is a not-for-profit organization founded by Allied Physicians Group, based in Melville, which distributes diapers to families in need across Long Island and beyond.

To learn more about the Allied Foundation and the Allied Diaper Bank of Long Island, please visit https://alliedfoundation.org/give/donate-diapers/ or call (631) 386-4185. For more information about Long Island Community Foundation, visit www.licf.org.

Photo courtesy of Allied Foundation

Pixabay photo

By David Dunaief, M.D.

Dr. David Dunaief

Many patients say they have been diagnosed with diverticulitis, but this is a misnomer. Diverticulitis is actually a consequence of diverticular disease, or diverticulosis, one of the most common maladies that affects us as we age. For instance, 35 percent of U.S. 50-year-olds are affected and, for those over the age of 60, approximately 58 percent are affected (1). Many will never experience symptoms.

The good news is that it is potentially preventable through modest lifestyle changes. My goal in writing this article is twofold: to explain simple ways to reduce your risk, while also debunking a myth that is pervasive — that fiber, or more specifically nuts and seeds, exacerbates the disease.

What is diverticular disease? 

It is a weakening of the lumen, or wall of the colon, resulting in the formation of pouches or out-pocketing referred to as diverticula. The cause of diverticula may be attributable to pressure from constipation. Its mildest form, diverticulosis may be asymptomatic. 

Symptoms of diverticular disease may include fever and abdominal pain, predominantly in the left lower quadrant in Western countries, or the right lower quadrant in Asian countries. It may need to be treated with antibiotics.

Diverticulitis affects 10 to 25 percent of those with diverticulosis. Diverticulitis is inflammation and infection, which may lead to a perforation of the bowel wall. If a rupture occurs, emergency surgery may be required.

Unfortunately, the incidence of diverticulitis is growing. As of 2010, about 200,000 are hospitalized for acute diverticulitis each year, and roughly 70,000 are hospitalized for diverticular bleeding (2).

How do you prevent diverticular disease and its complications? There are a number of modifiable risk factors, including fiber intake, weight and physical activity.

Fiber’s effects

In terms of fiber, there was a prospective (forward-looking) study published online in the British Medical Journal that extolled the value of fiber in reducing the risk of diverticular disease (3). This was part of the EPIC trial, involving over 47,000 people living in Scotland and England. The study showed a 31 percent reduction in risk in those who were vegetarian. 

But more intriguing, participants who had the highest fiber intake saw a 41 percent reduction in diverticular disease. Those participants in the highest fiber group consumed >25.5 grams per day for women and >26.1 grams per day for men, whereas those in the lowest group consumed less than 14 grams per day. Though the difference in fiber between the two groups was small, the reduction in risk was substantial. 

Another study, which analyzed data from the Million Women Study, a large-scale, population-based prospective UK study of middle-aged women, confirmed the correlation between fiber intake and diverticular disease, and further analyzed the impact of different sources of fiber (4). The authors’ findings were that reduction in the risk of diverticular disease was greatest with high intake of cereal and fruit fiber.

Most Americans get about 16 grams of fiber per day. The Institute of Medicine (IOM) recommends daily fiber intake for those <50 years old of 25-26 grams for women and 31-38 grams for men (5). Interestingly, their recommendations are lower for those who are over 50 years old.

Can you imagine what the effect is when people get at least 40 grams of fiber per day? This is what I recommend for my patients. Some foods that contain the most fiber include nuts, seeds, beans and legumes. In a study in 2009, specifically those men who consumed the most nuts and popcorn saw a protective effect from diverticulitis (6).

The role of obesity

Obesity plays a role, as well. In the large, prospective male Health Professionals Follow-up Study, body mass index played a significant role, as did waist circumference (7). Those who were obese (BMI >30 kg/m²) had a 78 percent increased risk of diverticulitis and a greater than threefold increased risk of a diverticular bleed compared to those who had a BMI in the normal range of <21 kg/m². For those whose waist circumference was in the highest group, they had a 56 percent increase risk of diverticulitis and a 96 percent increase risk of diverticular bleed. Thus, obesity puts patients at a much higher risk of the complications of diverticulosis.

Increasing physical activity

Physical activity is also important for reducing the risk of diverticular disease, although the exact mechanism is not yet understood. Regardless, the results are impressive. In a large prospective study, those with the greatest amount of exercise were 37 percent less likely to have diverticular disease compared to those with the least amount (8). Jogging and running seemed to have the most benefit. When the authors combined exercise with fiber intake, there was a dramatic 256 percent reduction in risk of this disease. 

Thus, preventing diverticular disease is based mostly on lifestyle modifications through diet and exercise.

References:

(1) www.niddk.nih.gov. (2) Clin Gastroenterol Hepatol. 2016; 14(1):96–103.e1. (3) BMJ. 2011; 343: d4131. (4) Gut. 2014 Sep; 63(9): 1450–1456. (5) Am J Lifestyle Med. 2017 Jan-Feb; 11(1): 80–85. (6) AMA 2008; 300: 907-914. (7) Gastroenterology. 2009;136(1):115. (8) Gut. 1995;36(2):276.  

Dr. David Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com. 

From left, Eleanor Lalima and Lisa Figueroa Filosa. Photo from Stony Brook Medicine

Two best friends on Long Island are now sharing a bond like no other, a set of kidneys.

Eleanor Lalima of Ronkonkoma and Lisa Figueroa Filosa of Deer Park have been best friends since they met in the 1st grade. Through getting married and having children of their own, the duo have stayed close throughout their more than 30 year friendship, so it wasn’t a surprise to anyone they knew when Lisa answered the call to help out when her friend needed her most.

Eleanor has been battling kidney disease since age 16. Not only did she face the disease, but she lost both her mother and her brother to kidney disease. While a patient at Stony Brook University Hospital (SBUH), Eleanor learned her next treatment option was receiving a kidney transplant. 

Soon after, Eleanor put out a call for help on Facebook. Several of Eleanor’s family and friends reached out right away to get tested including her lifelong best friend Lisa. Lisa was actually the first to get tested and called Eleanor to tell her she had a good match for a transplant.

“My mother was on the transplant list for over 8 years due to her rare blood type and she didn’t get the same chance I have now,” says Eleanor. “To get a kidney in such a short time is really amazing and it gives me a chance at a better life.”

Dr. Wayne Waltzer, Professor and Chairman of the Department of Urology and Director of Kidney Transplantation Program at Stony Brook University Hospital, and Dr. Frank Darras, Clinical/Medical Director of the Renal Transplantation Program at Stony Brook University Hospital, who cared for other members of her family, played a large role in Eleanor’s treatment at Stony Brook.

“Kidney disease can take a toll on an entire family. Being a transplant surgeon and being able to assist in restoring one’s quality of life is truly a rewarding experience,” said Dr. Darras. “But the true hero here is Lisa. Without her none of this would have been possible!”

On May 25, spirits were high as Eleanor and Lisa went in for surgery at SBUH. The surgery was a success and the friends were discharged within a week.

“Just when you think a lifelong friendship can’t be any stronger, you share a kidney,” said Lisa.

Kidney disease affects an estimated 37 million people in the U.S. (15% of the adult population; more than 1 in 7 adults). It is the leading cause of death in the U.S. according to the National Kidney Foundation, causing more deaths than breast cancer or prostate cancer.

For more information about Kidney Transplantation Services at Stony Brook Medicine, visit stonybrookmedicine.edu/patientcare/transplant.