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Christina Joselevitch

By Daniel Dunaief

Children knock on the door of 1313 Gluto Lane, a favorite house for Halloween. The resident, known for providing coveted confections at a rapid rate, immediately comes to the door, asks no questions about the Halloween costumes that might slow the process down and, with almost super-human speed, dumps candy into open bags and closes the door.

Word spreads about the house on Gluto Lane. Soon, the doorbell rings at a furious pace, with children eager to get the best candy of this difficult year and move on to the next house.

At first, with Trick or Treaters coming at a regular pace, the process works, but then, something goes awry, creepy music begins and the door doesn’t open.

That’s what’s happening in bipolar retinal cells in the goldfish Christina Joselevitch, a Postdoctoral Associate in the Neurobiology and Behavior Department at Stony Brook University’s Renaissance School of Medicine, is studying.

Known for their incredible speed at releasing neurotransmitters stored in circular vesicles, these bipolar retinal cells go through a depression in which they can’t release the neurotransmitter glutamate despite repeated signals for the release of the neurotransmitter.

“When you stimulate those cells very strongly, with two stimuli close apart, they suffer depression,” Joselevitch said. “Nobody knew why, if they’re able to signal constantly, they should suffer from depression.

To be sure, Joselevitch was working with extreme stimulation to probe the limits of the system and understand its underpinnings. This is not necessarily how these cells work. She said the researchers don’t know if retinal neurons experience synaptic depression under normal conditions and what function depression would have in bipolar cell physiology, in vision or in signaling processing in general.

In a recent publication in the Journal of Neuroscience, Joselevitch described at least two processes that contribute to this slowdown, which she describes as the rate limiting steps. The vesicles need to get to the membrane and they need to get ready to mature before they are release. Once vesicles move towards the cell membrane, they don’t immediately fuse and send their neurotransmitter into the synapse between cells. In some cells, such as the retinal photoreceptors and bipolar cells and in hair cells of the ear and lateral line in fish and in cells of the pineal gland, they gather in a ribbon close to calcium entry points.

Scientists have two theories of the ribbon function. The first is that it could act as a conveyor belt and speed up vesicle priming and delivery to the membrane and the second is that it could set a constant pace for vesicle delivery.

Joselevitch’s results suggest that the vesicles attach to the ribbon, where they go through a maturation process. These paired-pulse depressions don’t just occur in fish: they also affect the ability of mammalian cells to respond to a second stimulus.

These cellular phenomena show the limits of the system. Indeed, Joselevitch likened the process to a car that has reached its maximum speed. Pushing down harder or more on the accelerator won’t enable further acceleration.

The impact of this work is “broad,” she said. Studying this process could enable a stronger awareness of the steps in fast-acting processes in the nervous system. Such research could also provide an understanding about processes that go awry in various neurological diseases.

In an email, Professor Lonnie Wollmuth, who is the principal investigator for the Stony Brook lab in which Joselevitch works, described Joselevitch as “invaluable to our on-going efforts to study presynaptic mechanisms in the retina.” He wrote that she was an “outstanding and very careful scientist” who is “passionate” about her research and has served as a mentor for others in the lab.  Joselevitch has been working in Wollmuth’s lab for about 16 months.

Synaptic transmission is fundamental to all brain function, Wollmuth explained. “Changes in the strength of synaptic transmission underlie basic higher order brain functions like learning and memory,” the Stony Brook Professor wrote. Joselevitch’s experiments “reveal mechanisms of presynaptic vesicle release at all synapses and provide novel insights into the processing of vesicles at ribbon synapses.”

Based on Joselevitch’s work, Wollmuth’s lab has submitted a large National Institutes of Health grant to the National Eye Institute to study the molecular components of presynaptic release in the retina. She has also started to integrate her work with Alzheimer’s Disease, as proteins found in that disease disrupt the molecular machinery involved in presynaptic release.

A native of Brazil, Joselevitch has been at Stony Brook University since last July. She is on sabbatical with the University of São Paulo. She is hoping to participate in these studies in New York for a few more years.

She said she was “always a nerd,” and liked to study languages. With varying levels of proficiency, she speaks five languages: Portuguese, English, German, Dutch, and Spanish. At one point, she wanted to be an astronaut, but her mother Carmen dissuaded her from pursuing that interest.

Joselevitch had planned to return to Brazil to see her family in April, but had to cancel that plan because of a travel ban from the COVID-19 pandemic. She said her parents have been “good sports” and her father has bought a smartphone so he can talk through Skype or WhatsApp with his scientist daughter.

Joselevitch enjoys biking, hiking, singing and playing guitar and has been productive during the pandemic, writing papers and proposals. Stony Brook is nominating her work for consideration for the Warren Alpert Distinguished Scholar Award.

Wollmuth wrote that Joselevitch’s research forms “the foundation for future experiments to address the molecular components of vesicle dynamics.” Once they are identified, researchers can modulate and protect them in brain diseases.

Citing author James Joyce, Joselevitch explained her focus on neurons in the fish eye, which, she hopes, may lead to a broader understanding of neurology and disease. When asked why he wrote about Dublin when he could describe other places he’s visited, Joyce responded, “In the particular is contained the universal.”

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Get a flu shot now. 

While timing a flu shot can seem like timing the stock market — buying or selling a stock now might mean missing out on gains later — it’s not. A flu shot generally provides immunological coverage against the flu from about four weeks after the shot until six months later.

With a flu season that doesn’t follow a yearly calendar, residents sometimes try to balance between minimizing the possible effect of exposure to the flu in the next few weeks with exposure to the flu in the middle of the spring.

“It makes most health professionals very uncomfortable when people [suggest holding off on protection through the spring] as a reason to delay immunization, as it takes four weeks for protective antibodies to mature,” said Michael Grosso, Chief Medical Officer at Huntington Hospital. Influenza season can begin as early as November and sometimes earlier, so “any time now would be the right time.”

Medical professionals urged people to be even more proactive about getting a flu shot this year, as the pandemic continues to lurk in the shadows, on door knobs, and within six feet of an infected individual.

When people contract the flu along with other respiratory illnesses, the combination, as people might expect, can cause significant sickness.

“The novel coronavirus is just that, it’s novel,” Grosso said. “We don’t know exactly how it will interact with influenza. We do have significant prior experience with concurrent infections with other respiratory viruses. Individuals coinfected with one or more serious respiratory viruses frequently get sicker.”

That’s the case for both children and adults, Grosso added.

Getting an influenza vaccine could also reduce the confusion that will occur if people experience flu-like symptoms, which are also a hallmark of COVID-19 cases.

“Getting as much of the population immunized as possible is even more important than at other times,” Grosso said.

Each year, somewhere between 150,000 to 180,000 people are hospitalized from the flu and the death toll can range between 12,000 to 61,000 people per year in the U.S.

Doctors recommended that people who are 65 and older get a quadrivalent flu shot, which includes an additional influenza B strain.

In a trial of 30,000 people over 65, people who received the quadrivalent shot had 24% fewer illnesses compared to those who got the standard shot, according to the Centers for Disease Control and Prevention.

Susan Donelan, Medical Director of Healthcare Epidemiology at Stony Brook Medicine, said the side effects of the flu shot include an uncomfortable arm for a few days, a low grade fever and fatigue.

“The vast majority of people can easily manage the minor side effects for a day or two with Tylenol or Ibuprofen or a cold pack on their arm,” Dr. Donelan said.

Doctors said practices such as wearing a mask, social distancing and frequent hand washing, which are designed to reduce the spread of COVID-19, are also helpful in cutting down on the transmission of the flu.

Those measures will only help if residents exercise them correctly. Masks that fall below the nose of the wearer, which may make it easier to breathe, are not as effective at reducing the spread of these viruses, Dr. Donelan said.

 

By Melissa Arnold

It’s been a long year of Netflix binges and Zoom meetings for all of us, and these days, nothing feels better than getting out a little. You don’t have to go far to find interesting places to explore, either.

Most Long Island locals are probably familiar with the Suffolk County Vanderbilt Museum and Planetarium in Centerport, with its sprawling grounds, elaborate mansion and impressive collection of marine life. But be honest: When was your last visit? If it’s been a while — or even if it hasn’t — their 70th anniversary year is the perfect time to stop by.

“The Vanderbilt is unique, a don’t-miss slice of American history. When you take a guided tour of the mansion and its galleries, it’s a time machine trip to a remarkable era of privilege,” said Elizabeth Wayland-Morgan, executive director of the museum. “At one point in the past, there were more than 1,200 mansions on Long Island’s Gold Coast. This is one of the few that remains.”

The Vanderbilt Mansion as we know it today had relatively modest beginnings. William K. Vanderbilt II, a son of the famed Vanderbilt family, had just separated from his first wife in the early 1900s. “Willie K.,” as he’s affectionately known, was looking for a place to get a fresh start, away from the public eye. So he came to Centerport and purchased land, where he built a 7-room, English-style cottage along with some outbuildings.

The cottage, called Eagle’s Nest, was eventually expanded into a sprawling 24-room mansion in the Spanish Revival style. From 1910 to 1944, Eagle’s Nest was Vanderbilt’s summer hideaway. He and his second wife Rosamond hosted intimate gatherings of Vanderbilt family members and close friends, including the Duke and Duchess of Windsor, legendary golfer Sam Snead, and the Tiffanys.

Of course, that was just the beginning. According to Killian Taylor, the museum’s curatorial associate, Vanderbilt developed a fascination with all kinds of animals, the sea and the natural world from a young age. He had the opportunity to travel the world on his father’s yachts as a child, and longed to see more as he reached adulthood.

“Later, Willie K. inherited $20 million from his late father. One of the first things he did was purchase a very large yacht and hire a team of scientists and a crew,” Taylor explained. “With them, he began to travel and collect marine life, and by 1930, he had amassed one of the world’s largest private marine collections.”

With the help of scientists and experts from the American Museum of Natural History, Vanderbilt created galleries at the Estate to showcase his collections which contains more than 13,000 different marine specimens of all kinds and sizes, from the tiniest fish to a 32-foot whale shark, the world’s largest taxidermied fish, caught off Fire Island in 1935.

After Vanderbilt died in 1944, Rosamond continued to live in their Centerport mansion until her death in 1947. The 43-acre estate and museum – which remain frozen in time, exactly as they were in the late 1940s – opened to the public on July 6, 1950, following instructions left in Vanderbilt’s will. It was listed on the National Register of Historic Places in 1985.

The museum also features a 3,000-year-old mummy, which Vanderbilt purchased from an antique shop in Cairo, Egypt, Taylor said. The mummy even had an X-ray taken at nearby Stony Brook University Hospital, where they determined the remains are of a female around 25 years old.

“She doesn’t have a name out of respect for the fact that she was once a living woman with her own identity,” Taylor added.

The COVID-19 pandemic has brought its share of difficulties to every business, and while the museum has had to temporarily close some of its facilities, including the mansion’s living quarters and planetarium, they’ve also added new opportunities for visitors.

“Like many other museums, we had to get creative virtually very quickly,” said Wayland-Morgan. “Our Education Department created the ‘Explore’ series for children — fascinating facts about the lives of birds, butterflies, reptiles, and fish, with pictures to download and color. The Planetarium astronomy educators produced 11 videos on topics including How to Use a Telescope, Imagining Alien Life, Mars, Black Holes, and Fitness in Space. We’ve received very positive responses.” The planetarium also offers online astronomy classes.

The museum is also offering new outdoor programs on the grounds, including walking tours, sunset yoga, a popular series of bird talks by an ornithologist James MacDougall and are currently hosting the third annual Gardeners Showcase through September. On Fridays and Saturdays, movie-and-picnic nights are a popular draw at the outdoor, drive-in theater.

Even without a specific event to attend, the grounds are a perfect place to wander when cabin fever strikes.

“The best reason to visit right now is to stroll the grounds and gardens and visit the open galleries. We’ve also become a very popular picnic destination with a great view of Northport Bay,” Wayland-Morgan said. “We plan to reopen the mansion living quarters and planetarium later in the fall.”

The Suffolk County Vanderbilt Museum is located at 180 Little Neck Road, Centerport. As of Sept. 17, hours of operation are from noon to 5 p.m. on Tuesday, Friday, Saturday and Sunday. The mansion’s living quarters and the planetarium are currently closed. Please wear a mask and practice social distancing. Admission is $8 for adults, $5 for children under 12, and $7 for students and seniors. Children under 2 are admitted free. For questions and information, including movie night passes, visit www.vanderbiltmuseum.org or call 631-854-5579.

People from as far as Manhattan and as close as Centereach have been taking their vacations on Long Island, such as at the Fox & Owl Inn in Port Jefferson, instead of other states/countries where travel restrictions make it difficult. Photo from Rebecca Kassay

Residents of both Suffolk County and New York City have turned to local hotels and bed and breakfasts to enjoy time away from home amid limited travel options during the pandemic.

With out-of-state guests from numerous states limited in their travel to the area, corporate travel down considerably, and sports teams either shut down or playing without any fans, area hotels have still attracted guests from nearby towns and villages and from city residents disappointed with ongoing urban closures and eager to enjoy a natural setting.

People from as far as Manhattan and as close as Centereach have been taking their vacations on Long Island, such as at the Stony Brook Holiday Inn Express, instead of other states/countries where travel restrictions make it difficult. File photo

“It’s very different now,” said Jamie Ladone, sales executive at the Holiday Inn Express Stony Brook. “We’re not getting as many out-of-state guests,” but the hotel is finding people who are eager for a staycation.

Indeed, Emilie Zaniello and her family recently spent a weekend at the Holiday Inn, just 20 minutes from her home in Centereach

“We needed to get out of our element, to take a break from everyday life and the stresses right now,” said Zaniello, who stayed during a weekend with her husband John and their two children, 8-year-old Abigail, and 6-year-old John Robert.

The family felt “cooped up in the house” as their children didn’t have as much of an opportunity to do “normal, everyday things,” Zaniello said.

Abigail and John Robert enjoyed playing on the baseball field and the basketball court, while the family also booked time to go swimming.

“It just felt like a mini-vacation, where we didn’t have to go too far,” said Zaniello, who drove back and forth to her home to take care of the family’s two miniature dachshunds.

At the Holiday Inn, Suffolk residents have also enjoyed the indoor pool, outdoor patio, and volleyball and basketball courts, which families can use while maintaining social distancing, Ladone said. The hotel also has a putting green, horseshoes, and a baseball field and basketball court.

“We have people looking to spend quality time together like a family outdoors,” Ladone said.

The Holiday Inn has a meeting space upstairs with a seating capacity, under non-pandemic conditions, of 100. The hotel is hosting baby showers and corporate events outdoors on their patio.

The Holiday Inn has booked about 30 percent more outdoor parties than usual, Ladone said.

The Stony Brook hotel has also partnered with Spa Exotique, which offers massages or facials, and kayak packages with Stony Brook Harbor Kayak and Paddleboard.

Bed and Breakfast 

Bed and breakfasts in the area are also attracting attention from residents of Suffolk County and New York City.

At the Fox and Owl Inn in Port Jefferson, people are booking their rooms one to three weeks before they need them, reflecting the uncertainty about plans that might need to change amid fluid infection rates.

For the past two months, the Fox and Owl has been booking about 90 to 95 percent of their capacity, with a majority of the guests coming from New York City and Long Island rather than the usual far-flung locations across the country and world.

The bed and breakfast derived its name from “The Lord of the Rings” book series, which husband and wife owners Andrew Thomas and Rebecca Kassay enjoys. They each picked an animal that was native to the area and hoped to create a place that was akin to the respite the main characters felt when they visited an inn.

Kassay said the Inn has “kept up to date as far as the recommendations for cleaning and the response to the COVID-19.”

“It just felt like a mini-vacation, where we didn’t have to go too far.”

— Emilie Zaniello

The Fox and Owl is located in an 1850 Victorian home, which has large windows that Kassay keeps open as often as she can. Kassay and Thomas also use Lysol on surfaces regularly and ask their guests to wear masks in public.

While guests sit on sofas that are six feet apart, they have shared stories about their quarantine experiences and make predictions about what will happen next.

The Fox and Owl has three guest suites. Some family groups have booked the entire bed and breakfast, which is “really nice for families that are coming to visit other family members,” Kassay said. Groups of friends with similar quarantine habits who feel comfortable interacting with each other have also booked the entire Inn.

The Fox and Owl offers guests the use of a jacuzzi, which is complimentary with any booking. For an additional fee, the Inn provides S’Mores near the fire pit.

Kassay said she and Thomas appreciate that they can offer people an “escape and relief from the stress that everyone is handling.”

As the owner of a bed and breakfast, she said she has reflected on the challenge of remaining personable to guests even while wearing a mask. The daughter of a Sicilian mother, Kassay was raised to speak by using body language and by communicating with her hands as well as her words.

She noticed how guests have become “more expressive,” she said. “If you stop and look at people talking, there is more physicality to American’s interaction with one another.”

A resident of midtown, Mey, who preferred to use only her first name, said she and her boyfriend came to Port Jefferson to escape from the city and enjoy nature amid all the urban closures.

They planned to visit Port Jefferson for the day and wound up spending the night at the Fox and Owl Inn when they weren’t ready to drive back to Manhattan. Mey and her boyfriend enjoyed sitting on the porch, visiting a nearby park and eating ice cream.

“Port Jefferson has a lot of nature and the feeling of a vacation,” Mey said. The experience was “very chill.”

The Manhattanite enjoys attending Broadway shows when she is in the city, which are still closed.

The urban couple traveled to Long Island because they were “looking for something peaceful” and they “found it. Seeing green is better than seeing buildings.”

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People are using too much hand sanitizer. That’s one of several observations from Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital.

Sharon Nachman of SBU’s pediatrics department. Photo from SBU

Nachman suggests that sanitizer requires only a small amount on people’s hands. If, after applying it, someone has wet and sticky hands, they have overdone it.

“When I see people using hand sanitizer, they glop it on,” Nachman said in an interview. She recommends not using more than the standard volume, even amidst a return to school during the ongoing fallout from the COVID-19 pandemic.

In a wide-ranging conversation about the health of students who are returning to campus, Nachman urged students to pay closer attention to their health, to keep themselves and their classmates safe.

Students can tell if they’re too close to each other if they both reach out and can touch each other’s fingers.

The signs of COVID-19 in older teenagers and young 20-somethings are similar to the ones that occur in adults. They include fever, fatigue, feeling ill, loss of taste, and dry coughs. College students also have a high rate of being asymptomatic, which makes it difficult to find and isolate sick students.

While multi-symptom inflammatory disease in children, or MSI-C, cropped up during the worst of the pandemic in Suffolk County, the overall numbers of cases and infection rate on Long Island have fallen enough to reduce the likelihood of this COVID-related illness among children.

“Its all about how big the hit is in the community,” she said. “If you go to Texas or Florida, they are clearly seeing it. On Long Island, we aren’t seeing it” because of the way residents have helped flatten the infection curve among the population.

Nachman urged college students to be responsible when a contact tracer reaches out to them. In college campuses throughout the country, contact tracing will help mitigate the spread of the infection by quarantining people who might have been exposed to an active form of the virus. Isolating people will keep the spread of the virus in check.

Students, faculty and university administrators are well aware of the possibility that schools will need to return to an all-remote education model if infections reach a high enough level. Indeed, Nachman urged students to develop a plan for what they would pack and take home and where they would go if campuses closed. By being prepared for change, students can react to altered circumstances. High school students also need such preparation, in case any school that open need to close to protect students, faculty and staff.

As for the potential overlap of the flu and COVID, Nachman suggested students should get the flu shot by October, before the flu season begins.

Nachman is an advocate for masks.

“The smartest thing people can do is really wearing their masks,” she said. “Come to college prepared with enough masks that you can wash and wear them.”

The ideal number of masks is nothing fewer than two per day. She likes the washable ones, which are easy to put in the laundry and wash with the rest of a student’s clothing. The two-ply cloth masks work well and can be “personalized to reflect someone’s mood, to match clothing or to make a statement.”

Masks are important not only to protect other members of the student body, but also to protect the wearer.

“This idea that I’m wearing it to protect you is half right,” she said. “It’s protection for both of us.”

Colby Rowe and Roseanna Ryan making a delivery of over 100 iPads for patient-family communication. Photo by Scott Lamarsh

While Stony Brook University Hospital staff were taking care of the sickest residents in the midst of the pandemic in Suffolk County, residents did what they could to return the favor.

Colby Rowe’s truck is filled with 3M N95 masks. Photo by Colby Rowe

In addition to cheering for health care workers, first responders and essential employees each night at 7 p.m., numerous residents and businesses made donations of everything from lifesaving N95 masks to food to comfort care.

After 10 weeks of accepting donations from March through early June, Stony Brook had collected nearly one million pieces of personal protective equipment, including masks, gloves and head and food coverings, 33,500 comfort care items such as snacks, hand lotion, puzzles and coloring books, 18,000 meal donations, 575 video messages of support and 435 iPads for telemedicine.

These donations bolstered the spirits of the staff and provided vital comfort during everything from the process of conducting COVID-19 tests in the South P Lot to the recharging breaks doctors, nurses and hospital staff took after caring for patients.

“The comfort piece was a bit more striking for the patients and the staff,” said Roseanna Ryan, director of Patient Advocacy & Language Assistance Services at SBU Hospital. “The need for the staff to have a respite area to recharge during this extremely challenging time was something that we might not have initially anticipated. The donations we were able to use went such a long way.”

Indeed, even some of the smaller items helped the masked men and women health care heroes throughout the hospital system.

During testing, some of the medical professionals worked 12-hour shifts, administering test after test for reeling residents. Items such as breath mints, ChapStick and even eye coverings that would help health care workers take a nap in their car before returning for the next shift proved incredibly helpful, said Colby Rowe, Trauma Center Education & Prehospital outreach coordinator. Rowe worked with the emergency management team at the university, primarily coordinating the donation center.

“I received lots of text messages from people on the receiving end saying, ‘Thank you so much.’ They felt appreciated by the community, Rowe said.

Rowe added that the hospital performed ably in ensuring that the staff had sufficient PPE equipment to help them with their dangerous but important work.

The university took a wide range of assistance. Some donations, like snack food, found a home in the break room. Others, however, wound up helping people in different locations.

Stony Brook received more than 400 Easter baskets. Rowe was on the phone with a civilian friend from the U.S. Department of Defense, who told him that Fort Hamilton in Brooklyn had to postpone an Easter event.

Rowe loaded up his truck and drove the Easter baskets to Brooklyn. That’s not where the community spirit stopped. On the way, several baskets blew out of his truck on Route 347.

Snacks from the hospital break room at SBUH. Photo from Stony Brook University.

“I had about four cars pull over to help me” retrieve the boxes, Rowe said. “That’s a sign of the times.”
None of the boxes, which were donated to the children of soldiers, sustained any damage.

Rowe also said the university worked to make sure support staff, including housekeeping and the people moving the carts to usher patients around the hospital, benefited from these gifts.

The most consistent donated items were the three-dimensional printed face shields and hand sanitizer, which faculty who stayed to help frontline workers made on campus. In total, the university received more than 14,000 face shields and 509 gallons of hand sanitizer.

Ryan and Rowe said the hospital was grateful and humbled by each donation they received.
Several groups offered consistent gifts. The Three Village Coronavirus Forum Facebook group, which Three Village resident Michael Ehrlich led, raised hundreds each week through membership donations. They shopped at Target and Walmart to buy comfort care items.

Frito-Lay donated a couple of truckloads of chips to stock the respite room, while the Three Village Dads Foundation raised money to feed frontline workers.

The donations helped fill in some gaps during the year as well. National Nurses Week and National EMS week both occurred in May. While the hospital typically honors these professionals with gifts to show their appreciation, the response to COVID-19 was the priority during those times. The donations, however, provided material for care packages.

The pandemic triggered needs the hospital never had before, Ryan said.

“We had to identify different ways to allow our patients to communicate with their loved ones, while there was no visitation or limited visitation,” Ryan said. The hospital redeployed nursing staff into family liaison roles to provide friends and family with updates.

Rowe delivers Easter baskets to the families of soldiers at Fort Hamilton. Photo by Colby Rowe.

For the patients, the hospital put together comfort bags, which included activities like word searches, crossword puzzles, stress balls, aroma therapy, eye masks, and dry erase boards to allow patients who were able to write to communicate with nurses outside a door, which helped preserve PPE.

At this point, the university has some supplies left over, which it will likely use during the current, planned reopening of the university side of Stony Brook.

In addition to receiving donations from the community, Stony Brook also benefited from donations from people in other countries, including China, Korea and Germany.

“People sent really moving and emotional notes,” Rowe said. “We saw a lot of good in people” during a difficult time.

Ryan was also grateful for all the support from the university.

“The planning and preparation from senior leadership put us in a position where we were able to be successful in getting to the other side of this,” Ryan said. “Leadership at the state level also helped tremendously with that.”

Three Village Kids Lemonade Stand organizer Joseph Mastriano, bottom left, created a virtual R. C. Murphy Junior High School for a live streaming event Aug. 3. Image from Three Village Kids Lemonade Stand

With state guidelines mandating that events be kept to a reduced capacity or postponed due to the pandemic, the organizers of the Three Village Kids Lemonade Stand, Maddie and Joseph Mastriano, knew they would have to go about things differently this year.

For the eighth year in a row, the lemonade stand will raise money for the Stony Brook Children’s Hospital Child Life Program. However, this year there will be two events in one day.

Maddie Mastriano said she and her brother were hoping not to break their streak in having their annual lemonade stand.

“While it won’t be the same, we know this year more than ever finding a way to give back to our community is important,” Mastriano said. “COVID may have changed many things that we were used to doing, but we felt it very important to keep this summer tradition going. We made sure to take extra precautions in planning this time too, which is why we have two events planned on the same day. We really wanted to offer everyone an option to participate in a way they felt most comfortable doing so.”

A drive-through lemonade stand will take place at R.C. Murphy Junior High School Aug. 3 from 3 to 6 p.m. Mastriano said there will be a reduced number of volunteers this year and all of them will be wearing masks and gloves. Attendees will be required to stay in their cars, and tents will be staggered through the school’s bus circle.

The drive-through event will include prepackaged lemonade to go, do-it-yourself lemonade kits, raffles, sandwiches for sale by Chick-fil-A and a merchandise tent.

From 7:30 to 9:30 p.m. the same day, the young people will host a live virtual fundraiser on the streaming platform Twitch. During the virtual event, the raffle winners will be announced, and there will be an opportunity to donate directly to the GoFundMe page. District Lemonheads, which is the Three Village school that raises the most money for the cause, will also be announced.

Mastriano said they hope to have picture in picture during the stream, as they plan to be live on camera, air slideshows of past events and sponsor logos, as well as allow people to play along on a Minecraft server built by Joseph Mastriano and his friends. The Minecraft world will include a virtual lemonade stand that features the junior high school and game for participants to play.

Last year more than 500 attended the event at Murphy to buy 50-cent cups of lemonade, other treats and merchandise. Attendees played games, School of Rock students performed, and Stony Brook University athletes stopped by to visit. Sales from the 2019 lemonade stand exceeded the goal of $40,000 by the end of the day.

This year’s goal is $50,000 and nearly $6,000 has already been raised through the GoFundMe page.

The Three Village Kids Lemonade Stand username on Twitch is @3villagekidslemonadestand. R.C. Murphy Junior High School is located at 351 Oxhead Road, Stony Brook.

For more information, visit www.threevillagekidslemonadestand.com.

Photo from LIM
Grant will help fund new online educational programming

The Long Island Museum (LIM) announced on June 30 its award of a $59,713 grant from The National Endowment for the Humanities (NEH) to help fund the Museum’s new online educational programs that will be offered in the midst of the COVID-19 pandemic.

“We are thrilled and honored that the NEH is supporting our proposal of a new virtual educational program,” said Long Island Museum Executive Director Neil Watson.

“Since closing our doors in mid-March, the LIM staff has been working both creatively and tirelessly at meeting the needs of our community, particularly our school children and teachers,” he explained.

As so many of the museum’s standard offerings have transformed over these past four months, the need to dynamically adapt is ever apparent. After only a few weeks of their temporary closing, the LIM Launched the successful At Home With the LIM, a series of online family art and history activities, based on the Museum’s collection, historic buildings and grounds.

With school visits from many local districts in the fall likely to be greatly constrained, the LIM has since been making plans to redesign what they can offer schools with the use of technology.

“We believe objects from our collections provide uniquely visceral connections and learning opportunities,” said Joshua Ruff, Deputy Director, Director of Collections and Interpretations. “Realizing we are unable to bring school audiences to our collection, this project plans to bring the collection to them through remote field trips.”

The LIM will establish a “portable virtual classroom unit”, a mobile virtual studio with live streaming capability, to broadcast interactive classes from their unique historic buildings and museum galleries. To accommodate the virtual classrooms, the museum’s data network will be upgraded and expanded to teaching-critical areas museum wide by facilities/IT personnel.

Funds received from the NEH grant will enable the Museum’s Education Department to address the challenges schools will face in the 2020/2021 school year and allow the purchase and installation of essential upgrades to the data network of the LIM campus.

“In what is certain to be a school year filled with many firsts and changes, with this funding we can offer enriching new ways to make sure schools do not lose important connections to our museum,” said Lisa Unander, LIM’s Director of Education.

The Long Island Museum, located at 1200 Route 25A in Stony Brook, is one of 317 humanities projects in this round of funding. The $40.3 million in total grants nationwide will support vital research, education, and public programs in the humanities.

Marci Lobel. Photo from SBU

By Daniel Dunaief

Pregnant women with access to the outdoors are less stressed during the pandemic.

In fact, according to an unpublished finding that isn’t yet peer reviewed, pregnant women who had outdoor access were 67 percent less likely to worry about contracting the virus and 63 percent less likely to feel stress about being unprepared for the birth.

Lobel with a recent doctoral student, Jennifer Nicolo-SantaBarbara.

Stony Brook University recently awarded a project led by Dr. Heidi Preis in the Department of Psychology, with co-Principal Investigators Dr. Marci Lobel in the Department of Psychology and Dr. Brittain Mahaffey in the Department of Psychiatry and Behavioral Health that explored the link between stress and pregnancy. The researchers are hoping to identify what helps pregnant women and what may make them more vulnerable to the impacts of stress.

Stony Brook provided a total of $398,200 in seed funding to 17 research projects in response to the pandemic. Researchers at Stony Brook had put together 63 submissions, using a peer review process to choose the projects to fund, including the COVID-19 Pregnancy Experiences (or COPE) Study. The funding, which is for one year, is designed to provide the kind of seed funding that will lead to further research and that other funding agencies will support.

The COPE study tapped into a global network of collaborators that Lobel, who is the Director of the Stress and Reproduction Lab at SBU, established over the past 30 years to compare the different factors that mitigate or exacerbate stress for pregnant women in Spain, Israel, Italy, Germany Poland and Switzerland.

“The biological impact of COVID-19 is getting the lion’s share of attention, as it should,” said Lobel. “We don’t yet know enough about how the psychological impact will affect vulnerable groups, like pregnant women.”

Indeed, Lobel has spent three decades studying the effect of stress and related psychological factors on pregnancy. In other studies, major stressors, such as earthquakes, ice storms, and periods of warfare, confirm the toxic impact of prenatal stress, particularly for preterm births and low birth weight, she said.

Lobel and her colleagues created a self-report instrument called the Pandemic-Related Pregnancy Stress Scale, or PREPS, in which women report their specific concerns or anxieties caused by COVID-19.

Throughout the United States, the team sought responses from about 4,500 women recruited through social media at the end of April and the beginning of May.

Marci Lobel with her family at Yosemite in 2016. The photo credit is: Photo courtesy of Marci Lobel.

Among the women in the study, just over half of them were pregnant with their first child. In many studies that predated the current work, including some from her own research group, Lobel said women pregnant with their first child had higher levels of stress.

In some preliminary findings, 21.7 percent of pregnant women in the study reported severe levels of anxiety. “I think that is higher than what we typically would find in a population study of pregnant women,” Lobel said.

Women with a history of interpersonal violence also reported higher levels of stress and those whose prenatal appointments were canceled or altered were 1.78 times more likely to experience high stress related to a lack of preparedness and 1.49 times more likely to experience high stress related to worries about perinatal infection.

Some women in the study have found ways to reduce the accumulating stress about the health care crisis. The techniques that work for some women, Lobel said, may not work for others, suggesting that stress relief is specific to the individual and is usually determined by the situation itself.

“I don’t recommend any particular way of coping,” Lobel said. “What works for one may not work for another. It’s good to have a tool kit with lots of ways of coping.”

Indeed, some of the techniques pregnant women have found helpful include meditation, prayer, and faith-based practices. Pregnant women have also benefited from social support, which is particularly important during the pandemic when some women may feel “literally and figuratively isolated from others,” Lobel said.

Of all the research Lobel has done, the one that has received the most attention and landed her in the bible for pregnant women, “What to Expect When You’re Expecting,” was a study on optimism. She found that women who were more optimistic had better birth outcomes due in part to the better are they took of their health during pregnancy.

Coping with stress by avoidance predicts increases in emotional distress, Lobel explained. This corroborates much research which shows that avoidance is usually an ineffective way to cope with stress, except in limited cases such as when a stressful situation is brief and uncontrollable.

When people avoid the things that bother them, they can do it cognitively or through alcohol, which is especially dangerous for pregnant women and their developing fetuses. Avoidance can also involve excessive sleeping, as pregnant women may decide they don’t want to deal with life and stay in bed all day.

The scientists plan to collect a second set of data from these women, who were recruited through social media and who represent a diverse socioeconomic background, race and ethnicity, sexual orientation, and other factors, on July 15th.

Lobel said she already has some preliminary, unpublished findings from Poland, which are showing the same kinds of stressors and distress among pregnant women. Polish women have expressed stress related to worries about lack of preparation for birth during the pandemic and stress related to worries about infection.

Lobel said the researchers hope to explore a host of questions as they collect more information. They hope to look at obsessions and compulsions and would like to measure anger. They also will measure levels of depression and anxiety and will compare that to the norms for non-pregnant women.

On the other side of the stress meter, the group will study how being pregnant during the pandemic may help some women appreciate their pregnancy more. For some women, the pregnancy may give them strength to deal with the pandemic, as they focus on having a baby.

The researchers will also explore the level of control women feel over the outcome of their pregnancy and the health of their baby. Feeling in control can create a positive response associated with lower distress.

While Lobel and her colleagues won’t answer all these questions in a year, they hope their initial studies will lead to more funding and research. “Hopefully, we’ll get a [National Institutes of Health] grant to follow up these women for a couple of years to study them and their children to see if there are any developmental or mental or physical health effects” of the pandemic.

Gary Degrijze thanks healthcare heroes that cared for him at Stony Brook University Hospital. Photo from Stony Brook Medicine

Gary Degrijze, an Army veteran, has climbed out of a deep health hole caused by COVID-19.

Gary sees his wife Ana for the first time in over two months. He was admitted into Stony Brook University Hospital on March 22 and discharged on June 5. Photo from Stony Brook Medicine

A Bellport resident and father of four, Degrijze, 48, spent seven weeks on a ventilator at Stony Brook University Hospital, clinging to life.

“When he was in the [Intensive Care Unit], he lost his pulse at least two times,” Jerry Rubano, a doctor in Trauma/ Acute Care/ Surgical Critical Care in the Department of Surgery at Stony Brook Medicine, said in a press release. “His kidneys stopped working for about a month where he was on continuous dialysis and his lungs were probably some of the worst that we’ve seen. He was as sick as can be.”

The medical team at Stony Brook stayed in touch with Gary’s wife Ana Degrijze every day, providing updates on his health.

“I had a nurse calling me every day after the rounds were done,” Degrijze said in the release. “I thought that was so great.”

Degrijze had a tracheostomy and was taken off the ventilator on May 11. After he no longer needed the ventilator, he saw his wife and four children after two months.

“I don’t remember anything that happened while I was intubated,” Degrijze said..

Degrijze, who was discharged on June 5, is in rehab, where he will work on regaining motion in his arms. He would like to serve another five years in the Army Reserve and retire after 20 years of service.

Degrijze has “truly made a remarkable recovery,” Rubano said. “His determination and the dedication of the team taking care of him have made all the difference.”