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By Jeffrey Sanzel

Public radio personality and prolific author David Bouchier has gathered 122 essays in his newest collection, the charming “Out of Thin Air.” Divided into seven loose themes covering such topics as technology, politics and travel, Bouchier covers many of the same ideas but always from a different angle. As they are based on his well-known radio commentaries, each essay is a clever gem, rarely more than two pages, and makes for insightful and entertaining reading.

Author David Bouchier

In the Preface, Bouchier defines an essay as “the writer talking to you, one on one, about something that he or she finds interesting, annoying, bewildering, or funny.” This definitive statement guides the entire work. As we wend our way through his experiences, it is as if he is sitting across from us over a lively coffee. He is articulate and witty and, even when he is at his most hyperbolic, there is a sincerity that comes through.

Bouchier’s first essay, “Waiting for the End” appropriately deals with just that — the end of the world. He clearly gives us a sense of his life’s view and what will come in the ensuing pages: “The future is virgin territory, and any pessimist can claim it.” When writing of a cinematic look at the apocalypse: “The movie was two hours and thirty-eight minutes long. The actual end of the world needs to be snappier than that, or we will lose interest (average adult attention span: twenty minutes).” We now know who Bouchier is and can proceed in the full knowledge that we will laugh and be inspired in turns or, just as often, simultaneously.

Much of the book is taken up with issues of modern technology and the disenfranchisement of people of an earlier generation. What separates Bouchier from the usual curmudgeonly wheezes is that he has — albeit sometimes reluctantly — embraced not just the power of these changes but their necessity. Not that he doesn’t take many pointed and highly amusing shots at our slavish addiction to all things computer centric; he rails against them but still sees their value. “We are never alone unless the battery runs out.” He is not so much technophobic but “techno-wary.” Of cellphones, “I talk, therefore I am” is followed by his taking it a step further that this form of communication brings us closer to each other and yet isolates us from the world.

In his longest essay, “The Ghost in the Machine,” Bouchier makes the valid point that computers have rid us of the need for memory. With instant access, we have disconnected from ourselves and no actually living is done. We have become a society that survives in a virtual existence. While he is going to the extreme to make his point, there is a reality in his argument that demands we look inward.

“From Hardware to Software” is a laugh-out-loud equation of old-fashioned hardware stores with the heroic doctors of television drama with the dramatic of-course-it-can-be-saved. It reflects on a time when problems had solutions and mourns the loss of these kinder bastions of help and support and knowledge. In the same vein, the author writes a paean to the joy of the manual typewriter, gone the same way is these shops.

What helps enrich the pieces is that Bouchier is incredibly well-read and knowledgeable in a wide range of topics — literature (novels in particular), art and science to name a few. He encourages the reader to embrace science — even if you don’t understand it. He praises continuing education but never laments that education is wasted on the young. It gives a vast scope for interpretation and reference that enriches the depth of his exploration.

As stated, many subjects overlap (notably cellphones, computers and other contemporary gadgetry), but he manages to mine a different perspective with each vignette: He finds a singular awareness to highlight.

The topics that are covered are plentiful. The author’s thoughts touch on ideas from “selective forgetting” (a wonderfully accurate concept) to the danger of the smiley face. He pursues the danger of teaching fake history and the repercussions on young (and older) minds. Here, like so many places in his writing, he shifts easily from his acerbic and pithy quips to important concepts such as learning from history, not just ingest it.

Bouchier’s take on the opposite of procrastination — “pre-crastination” — is amusing and not a little disturbing; he finds that people who rush into things are not giving the proper thought. This leads to a siting of truly dangerous things that should give people pause: “double bacon cheeseburgers with fries, international wars, and marriage.” Even when taking aim at easy targets, his perceptions are both fresh and refreshing. Ultimately, in “We’ll Do This Later,” somehow he makes a strong case for procrastination. He is also adept at looking at two sides of a situation.

In “The Way We Were,” the author starts out with a pointedly ambivalent view of reunions but then comes to a much more introspective conclusion, finding the worth in the event. It is not just that he finds the two views but he is able to perceive multiple awarenesses.

“Worth Preserving” is a timely solution for maintaining historical sites. What is fascinating is that at first it seems like he is being tongue-in-cheek — and he might possibly be — but the concepts of preservation and accessibility are sound. It is this blend of humor and understanding that fuel his writing.

And yet, Bouchier’s take on nostalgia comes at the discussion from a different standpoint: “Every nation has its own tales of a glorious past that never existed.” He gives Downton Abbey as a prime example that the truth is much darker below stairs. Basically, the good old days that are glorified by film, television and novels never existed.

He laments the bookless bookstores that have become clothing emporiums — most notably university bookstores where books are screens “to goggle or Google at.” Clever word play is powerful and his succinctness is an arrow to the center, his dissections as swift and accurate as a scalpel.

“Losing stuff, like losing weight, is a lost cause.” We have too many things — we are saturated as “willing prisoners” of our acquisitions. Again, he turns his accusations inward and finds the positive in what has become a negative cliché — he finds the value in “stuff” as a connection to who we are related to from where we’ve come.

The author’s thoughts about wedding extravagance are really an exploration of marriage in the short and long term, calling to task the reality that in the modern age being average and fitting in trumps being Mozart. In the age of driverless cars, perhaps it is not the vehicles that should be recalled but the drivers themselves. In a flip on red-light cameras, he makes the case to reward good drivers for correct behavior.

The selfie as “a sudden plague of pathological vanity” is extreme — but not inaccurate, flying in the face of the cliché of a picture being worth a thousand words. The “Look at me, I’m here, I exist” is no more than a “flicker across the consciousness leaving no trace. They’re not worth a thousand words, they replace a thousand words.”

There is a great deal of strong advice in Bouchier’s writings. In “A Good Long Read,” he meditates on the transition from reading long books to embracing a series of books. This is a healthy and helpful suggestion to readers of desire but limited time.

An extended section on politics in the book should be made required reading in every school (and home, for that matter). The author’s view on the American system can be summed up in his observation that we have hundreds of choices for cereal but only two for president. He writes about the true heroes of our times and times past as well as a fascinating connection between clowns, Halloween and Election Day.

A discussion of a universal draft — men, woman, all ages an socioeconomic backgrounds — ultimately hints at broader ideas. He does the same thing with a darkly comic advocation of making everyone in the world an American. In his section on travel, Bouchier opens up with “Escape Attempts,” which hints at deeper themes — going from trips to war to marriage and children. He makes profound statements about the power of inner life, of reading versus travel. He points out that “to” is often less important than “from.” Style of travel from point of view as well as the unnecessary obsession with souvenirs all encourage us to look not just in the mirror but within ourselves.

The essay “The Business of America” is the smartest and most accurate assessment of the lack of values in our constant pursuit of meetings. In the “Right to Arm Bears,” Bouchier proposes leveling the hunting playing field by providing animals with guns. “Philosophy in the Slow Lane” meditates on life in the Long Island Expressway traffic jams, comparing it to the classic audio novels (Twain, Melville) he listens to when caught in the given congestion of our daily lives. All pithy statements; all with great truths beneath.

The best summation of Bouchier’s work would be in his own words: “What makes us different from bees and lemmings is that we can and do break away from the herd, and think our separate thoughts. We are bees with a perspective on the hive, which allows us to evolve and to create. It also gives us a headache.”

Thank you, Mr. Bouchier for the reminder of all the former. And your tag to this thought reminds us never to take ourselves too seriously.

‘Out of Thin Air’ is available online at www.amazon.com. Meet author David Bouchier at the Third Friday event at the Reboli Center for Art and History, 64 Main St., Stony Brook on Friday, Dec. 15 at 6 p.m. Bouchier will discuss his 25 years on public radio. The event is free.

LISCA performed at the Basilica of St. Francis of Assisi during a concert tour of Italy. Photo by Candice Foley

By Kevin Redding

A Stony Brook University-born singing ensemble is celebrating its 50th anniversary on a high note.

The Long Island Symphonic Choral Association (LISCA), formed in 1968, will take to St. James Roman Catholic Church in Setauket on Dec. 8 for its most grandiose performance yet. The nonprofit group, made up of roughly 70 diverse members ranging in age from early 20s to 80 who have put on concerts around the world, will deliver a program of works by Igor Stravinsky and Arvo Part, to name a few, in honor of its late, great founder Gregg Smith, an internationally renowned choral conductor and composer who died last year.

“We designed this to reflect the many different kinds of things we have sung over the 50 years of our existence,” said Norma Watson, a member since the group formed. “The mission has always been to present excellent performances of not frequently heard music. We’ve done premieres of great modern composers and sang the pieces of Renaissance masters. It’s been fun to go back and sing these songs again. I’ll never get tired of singing with this group. ”

Among the highlights of the upcoming concert, which will run about an hour and a half and culminate in a giant meet-and-greet reception in the church’s downstairs, are “Heilig” (Holy) by Felix Mendelssohn, “O Magnum Mysterium by Morten Lauridsen, “Ave Maria, “Pater Noster” and “Russian Credo” by Stravinsky, and the Long Island premiere of “A Mary Trilogy” composed by Smith himself.

Smith, who died of a heart attack at 84 in July 2016, served as LISCA’s conductor from 1968 until 2005. The mantle was then passed over to Thomas Schmidt, who conducted through 2016. Since January, the group has been led by 32-year-old Eric Stewart, a composer-in-residence at St. Peter’s Lutheran Church in New York City and conductor of the Tzu Chi Youth Chamber Orchestra on Long Island whose own work was recognized and encouraged by Smith.

As a Stony Brook University student and member of the University Community Chorus in the late 1960s, Watson met Smith when he arrived as director of choral music. Soon after being hired, the conductor — who established new standards of professional choral singing with the Gregg Smith Singers, a group founded in 1955 and famous for showcasing the music of contemporary American composers and not doing “the usual sort of choral programs,” as Smith told The New York Times in 1977 — changed the name of the college’s choir to LISCA to broaden the group’s ambitions and welcome collaborations with symphony orchestras.

Eric Stewart

“We weren’t really singing challenging stuff initially,” Watson said of the choir before Smith came on board. “What made me want to sing were the ambition he had to make us a really great choir and sing interesting pieces we weren’t used to singing.”

One of the group’s first concerts revolved around a major piece by Stravinsky, a composer Smith knew well who was in attendance to see their performance. Smith’s other acquaintances included Dave Brubeck and Elliott Carter, now legendary composers who watched the choir sing their charts. They have performed concerts in Spain, France, England, Ireland and Iceland.

“Gregg had such an exciting and unpredictable approach,” said Joe Dyro, the president of LISCA and a singer in the bass section since 1980. “He had a brilliant way of making things turn out right for the performance, helping us singers blend. I feel very honored to be part of a group that has such a large legacy.”

Dyro said he was singing while waiting to pay at a restaurant at the Smith Haven Mall when he got a tap on the shoulder from a member of LISCA, who extended an invite to join the group.

“I’m humbled because I know that many of the singers in the group are much better musicians and much more learned. I’m trying my best to keep up with the rest of the crowd,” Dyro said, laughing. “And Eric is a young, exciting conductor who, I think, is going to bring new vitality to the choir.”

Sidonie Morrison, a soprano in the choir since 1981, also spoke highly of LISCA’s new leader. “He’s very enthusiastic and fun to work with. We’re looking forward to a different kind of concert with him,” he said.

It will be an especially poignant night for Stewart, who made his LISCA debut when he conducted the group’s May concert. He points to Smith as the first person to seriously look at his original compositions when he first moved to New York City in 2010. Smith was so taken by the young musician’s work that he made sure to perform it with a professional ensemble.

“It’s because of him that I saw how amazing a choral ensemble could sound,” Stewart said. “He really opened up a whole new mode of expression for me as a composer and meant a lot to me on my path to becoming a professional musician. It’s truly an honor to pay tribute to him and his contributions with LISCA, with whom I’m extremely impressed. Some of these pieces are quite difficult and they’ve been able to take on the challenge. I’m quite excited about it.”

This year’s LISCA concert is in honor of the group’s late conductor, Gregg Smith, pictured above. Photo from LISCA

PROGRAM:

Felix Mendelssohn:

“Heilig” (Holy) for double choir

Arvo Part: “Magnificat”

Giovanni Gabrieli: “Beata es Virgo,” “Jubilate Deo” and “O Magnum Mysterium” for double chorus and brass Morten Lauridsen: “O Magnum Mysterium”

Gustav Holst: “Christmas Day” and “In the Bleak Midwinter”

Igor Stravinsky: “Ave Maria,” “Pater Noster” and “Russian Credo”

Gregg Smith: “A Mary Trilogy” and “Alleluia: Vom Himmel Hoch”

The concert begins at 8 p.m. at St. James Roman Catholic Church, 429 Route 25A in Setauket on Friday, Dec. 8. Tickets, which are available at the door and at www/lisca.org, are $25 adults, $20 for seniors, and free for students. For further information, please call 631-751-2743.

 

Above, Israel Kleinberg, right, with Mitch Goldberg, president of Ortek Therapeutics

By Daniel Dunaief

What if dentists could see developing cavities earlier? What if, once they discovered these potential problems, they could help their patients protect their teeth and avoid fillings? And, to top it off, what if they could do this without exposing their patients to radiation from X-rays?

The Electronic Cavity Detector

That’s exactly what Israel Kleinberg, a longtime Stony Brook University dental researcher and the founding director of the Division of Translational Oral Biology at SBU, recently developed. Called the electronic cavity detector, this new tool was recently approved by the Food and Drug Administration.

The device monitors mineral loss in enamel of molars and premolars. Powered by a battery, the handheld ECD uses electrical conductance to diagnose and monitor lesions. Tooth enamel does not conduct a signal. A lesion or crack in the enamel, however, will allow the ECD to record an early indication of a developing cavity.

“The ECD can detect lesions that are microscopic and [detect them] much sooner than X-rays,” Kleinberg explained in an email. Other research has shown that “X-rays are not very effective for diagnosing incipient enamel caries [cavities], though the technique is very useful for diagnosing deeper lesions.”

Ortek Therapeutics, a small company based in Roslyn Heights, supported the research to develop the technology over the last 10 years. Ortek is developing plans to commercialize the ECD, which could be available at a neighborhood dentist’s office by the middle of next year.

Mitch Goldberg, the president of Ortek, said the response to a positive reading on the ECD will depend on the dental practitioner. A very low conductance number could suggest a dentist pay further attention to the specific tooth. It might also lead a dentist to suggest improving oral care, brushing better or prescribing a fluoride rinse, among other options.“If the number is higher, the dentist will decide the appropriate treatment option, which could include minimally invasive procedures,” Goldberg said.

Goldberg, whose firm invested over $1 million in the work, is excited about the prospects for the ECD, for which Ortek filed and received a patent and then went through the FDA approval process. “It’s a painless” way to monitor teeth, Goldberg said. “There’s no radiation [involved].”

To be sure, he said the ECD won’t replace X-rays, particularly for teeth that already have a crown or other dental work or that are already known to have cracks or fissures. Still, Goldberg said this device could help monitor back teeth, where tiny lesions would not be causing a patient pain. The examination itself will require a short exam by either a hygienist or a dentist, who can put a probe in the bottom of a groove and gently move it along the tooth.

Any dental professional could be “trained on this in about 15 minutes,” Goldberg said. “They do similar types of work when they are probing and cleaning” teeth. Practitioners would likely understand the approach quickly, he said.

To operate the device, a dentist places a lip hook in the patient’s mouth. The dentist then puts a cotton roll between the tooth and the cheek, then air dries the tooth, Kleinberg explained in an email. The dentist lightly touches the tooth with the ECD probe and testing is completed in seconds.

Israel Kleinberg

Kleinberg, who has been developing this device for 14 years, suggested that the most common potential causes of false readings might be failure to dry the surface and operator error. The researcher developed this product with Stony Brook University Research Assistants Robi Chatterjee and Fred Confessore.

The partnership with Stony Brook has been a “win-win” for Ortek. Indeed, Kleinberg also developed a product called BasicBites. The chewable BasicBites provide a pH environment that supports healthy bacteria in the mouth. At the same time, BasicBites makes it harder for the bacteria that eats sugars and produces acids that wear away minerals on teeth to survive. The product make it tough for the acid-producing bacteria to eat food leftovers stuck between or around teeth.

Kleinberg, who has been with Stony Brook for 44 years, still works full time and shows no signs of slowing down. The researcher is the founding chairman of the Department of Oral Biology and Pathology. He stepped down from that position in 2009. Goldberg said he speaks with Kleinberg several times a week and calls his partner in cavity fighting an “inspiration,” adding that Kleinberg is considered the grandfather of oral biology.

Goldberg said he has a great sense of satisfaction when he goes to a pharmacy. “I take a glance at some of the products on store shelves that came out of Stony Brook and Ortek and it does give me tremendous pride,” he said.

Goldberg said he can’t disclose the market size for the ECD. He added that there are over 100,000 general dentists in the country who treat people of all ages. “There’s a tremendous opportunity for us,” he said, suggesting that dentists could check for any signs of early tooth decay before putting on a sealant.

Taking a similar approach to the BasicBites work, Kleinberg, with support from Ortek, is also researching skin-related technology for fighting MRSA-related infections and body odor. Goldberg said unwelcome bacteria often contribute to unpleasant smells that come off the skin. Ortek is also promoting the growth of healthy bacteria that reduce those scents.

While still in the early stages of development, Kleinberg has “developed a patented cutaneous or skin microbiome technology that promotes the growth of beneficial bacteria while crowding out harmful microbes,” Goldberg said. By exploring the microbiome, Kleinberg can promote the growth of better bacteria in the feet and under the arms.

MEET ZARA! What a beautiful name this little girl has! Meaning ‘princess’ in Russian and ‘star’ or ‘flower’ in Arabic, Zara is a 2-year-old Chihuahua mix who was just rescued from a high kill shelter in Texas and is safe now at Kent Animal Shelter. Although she’s only been there a short time, she is a favorite among the volunteers who have fallen in love with her sweet and friendly disposition and her beautiful brown eyes. By the time she is adopted, Zara will be spayed, microchipped and up to date on all her vaccines. Wouldn’t she be a lovely addition to your family for the holidays?

Kent Animal Shelter is located at 2259 River Road in Calverton. For more information on Zara and other adoptable pets at Kent, please call 631-727-5731 or visit www.kentanimalshelter.com.

Update: Zara has been adopted!

Interior designers, garden clubs deck the elegant halls

The Suffolk County Vanderbilt Museum’s holiday centerpiece is the mansion of William and Rosamond Vanderbilt, decorated each year by local designers and garden clubs. Their creative touch brings additional charm and magic to the spectacular, 24-room, Spanish-Revival house, which is listed on the National Register of Historic Places. Visitors can see the captivating results from now through January. The decorators create magic in the rooms with lighted trees, boughs, ornaments, wreaths, ribbons, garlands and elegantly wrapped faux gifts.

Decorating the mansion this year were the Asharoken, Dix Hills, Centerport, Honey Hills, Nathan Hale and Three Village (Old Field, Setauket and Stony Brook) garden clubs; Harbor Homestead & Co. Design of Centerport; and gardeners from the Cornell Cooperative Extension of Suffolk County.

Stephanie Gress, the museum’s director of curatorial affairs, said “Most of these garden clubs and designers have been decorating the mansion for more than 20 seasons. “We look forward to seeing them each year, and to how they use their creative skills to bring elegant holiday charm to the house.” Gress and the curatorial staff decorated the Windsor Guest Room, Breakfast Hallway, Lancaster Room and Northport Porch.

Christine Lagana and a group of friends from the Dix Hills Garden Club decorated the large tree in the mansion library and placed gifts beneath it. They also added garland and ornaments as well as white poinsettias and red ribbons to the mantelpiece over the large fireplace and artful groups of large, mirrored ornaments on side tables.

Mary Schlotter and her daughter, Krishtia McCord — who operate the Centerport design firm Harbor Homestead & Co. — decorated Rosamond Vanderbilt’s mirrored dressing room and the arcade that connects the nursery wing with the front entrance of the mansion. They decorated a live tree in the Sundial Garden off the arcade and hung icicles and silver-sprayed vines, harvested locally, from the arcade ceiling beams.

For Mrs. Vanderbilt’s dressing room, using a dress-form mannequin, they created a skirt with green boughs. “Our friend, dress designer Lorri Kessler-Toth of Couture Creations, created a fitted turquoise-blue velvet cover for the dress-form torso,” Schlotter said. “We added a necklace of chandelier crystals and a pendant and embellished the skirt with teal ornaments, champagne ribbon and filigreed poinsettia leaves. This is a dressing room, so we created a Christmas dress.”

Schlotter and McCord added chandelier crystals and champagne poinsettia leaves to the bough that decorates the mantelpiece on the marble fireplace. The crystals on the mantel complement those that hang from the sconces in the mirrored, hexagonal dressing room.

The Asharoken Garden Club, returning after many years, decorated Mrs. Vanderbilt’s bedroom with colors that reflect her love of pearls, Gress said, including copper, cream and gold. The Centerport club embellished the guest room of Sonja Henie (three-time Olympic skating champion, movie star, and family friend) and William Vanderbilt’s bedroom. The wreaths, garlands and large golden ornaments in Mr. Vanderbilt’s room were highlighted by pots of elegant red amaryllis, a stunning seasonal flower. They also placed garland and tall, thin trees, hung with ornaments, on the mantelpiece.

The Nathan Hale club, which decorated the Organ Room, clipped old-fashioned candles with brass holders and wax-catchers on the branches of the tree. Members added garland and cherubs to the carved mantelpiece and placed arrangements of gold-sprayed pine cones and scallop and whelk shells on tables.

In the Portuguese Sitting Room, in the original wing of the mansion, the Honey Hill club placed Tiffany packages beneath the tree and added small holiday touches around the room. The Cornell Cooperative Extension gardeners worked outside, adding flourishes to the mansion windows with live wreaths, trimmed with flowers, fruits and ribbons. “These generous volunteers use their time and talent to create an atmosphere of charming holiday grandeur and sophisticated living,” said Lance Reinheimer, executive director of the Vanderbilt Museum. “We’re grateful to them for bringing magic to this historic house.”

Visiting the Vanderbilt Museum:

Now that the Vanderbilt mansion and its halls are decked elegantly for the season, the public is invited to see the home at its most magical time. Guided tours of the decorated Vanderbilt mansion continue each Tuesday, Saturday and Sunday at 12:30, 1, 2, 3 and 4 p.m. — and on Tuesday, Dec. 26, through Saturday, Dec. 30. (Visitors pay the general admission fee plus $6 per person for a tour.)

Special Twilight Tours will be given for two days only: Wednesday and Thursday, Dec. 27 and 28, from 6 to 8 p.m. Admission is $10 for adults, $9 for students and seniors (62 and older) and $5 for children 12 and under.

The Vanderbilt Museum and Reichert Planetarium will be open from noon to 4 p.m. on Dec. 26 to 30 and will be closed on Christmas Eve, Christmas Day, New Year’s Eve and New Year’s Day.

The Suffolk County Vanderbilt Museum is located at 180 Little Neck Road in Centerport. For more information, call 631-854-5579 or visit www.vanderbiltmuseum.org.

 

On Dec. 3, legends and spies from history such as Culper Spy Ring members Major Benjamin Tallmadge and Caleb Brewster, prominent shipbuilder Jonas Smith and philanthropists Ward and Dorothy Melville joined Stony Brook and neighboring residents to ring in the holiday season.

The village’s 38th annual holiday festival featured the historic characters in giant puppet form, created by Processional Arts Workshop, during the event’s Puppets Processional led by The Jazz Loft owner Tom Manuel and his band. Santa was on hand to hear all the children’s’ wishes and take photos. Additional activities at the event organized by The Ward Melville Heritage Organization included live music with WALK Radio; a performance by Roseland School of Dance; carolers; a holiday train display at the Cultural Center; and Wiggs Optician’s holiday windows.

Joel Saltz. Photo from SBU

By Daniel Dunaief

In the battle against cancer, doctors and scientists use targeted drugs to treat the disease. They also employ radiation, starve it of the nutrients it might need to grow, block key metabolic pathways in its development and encourage the immune system to attack these genetically misdirected cells that grow out of control. A developing field in this battle includes the use of computers, artificial intelligence and math.

Joel Saltz, the Cherith Chair of Biomedical Informatics at Stony Brook University, recently teamed up with researchers from Emory University and the University of Arkansas and won an $8 million grant from the National Cancer Institute to coordinate radiology and pathology information in the battle against cancer.

“By gathering more information, researchers can understand better what’s happening, what might happen and how best to treat cancer,” Saltz said. The grant will be divided equally among the three institutions over the course of five years. Saltz will be collaborating with Ashish Sharma at Emory and Fred Prior at the University of Arkansas.

Saltz has been working with Sharma for several years, when the two were at Ohio State and then moved together to Emory. This is Saltz’s first major grant with Prior, although the two have also known each other for years and have been working in the same NCI program.

Prior has considerable expertise in radiology, while Saltz is adding his pathology background to the mix. Radiology has used digital imaging for a long time and, until recently, pathology data was collected on glass slides. Saltz is helping bring digital pathology to this effort.

“We had been on panels for many years with NCI saying we need to do this sort of” collaboration, Saltz added, and now the trio is putting that idea to work.

Yusuf Hannun, the director of the Cancer Center at Stony Brook, sees the potential for this type of collaboration. “This is a very important effort that builds on several areas of outstanding strength” at the Cancer Center, the director explained in an email.

Exploring information from digitized radiology and pathology samples will “allow us to understand individual cancers at a much higher level. It should improve accuracy in diagnosis [and offer an] ability to provide better informed prognosis” and individual therapy, Hannun continued.

Researchers on the current grant, which is part of the Information Technology for Cancer Research, plan to expand resources for integrative imaging studies, build on the capacity to acquire high-quality data collections, dedicate resources to support reproducible research and increase community engagement.

Saltz will use the portion of the Stony Brook funds to develop new software integration tools and curation and work with researchers to analyze and understand their patient data. Over time, he will also hire additional staff to build out this expertise. He has collaborated with Kenneth Shroyer, chair of the Department of Pathology at Stony Brook, on pancreatic and ovarian cancer and on breast cancer with pathology professor Patricia Thompson, who is also director of basic science at the Cancer Center. Shroyer “plays an important role” in all his research, Saltz said.

“Digital pathology will supplement that art of surgical pathology with quantitative data, to improve diagnostic accuracy,” Shroyer wrote in an email, which will “inform decisions on how to optimize therapeutic intervention for the treatment of cancer and many other diseases.”

Shroyer interviewed Saltz before Stony Brook hired its first bioinformatics chair. “Based on his research focus, including his pioneering efforts in digital pathology, he clearly stood out as my top choice.”

Saltz and Shroyer have generated maps of patterns for immune cells in tumors. “We and others have shown that these are related to how patients respond to treatment,” Saltz said. He described his work with these scientists as “basic clinical cancer research,” in which he develops and enhances technology to understand various types of cancer.

This particular grant is “more about technology and curation,” Saltz said. “People are developing new algorithms, in artificial intelligence and machine learning.” By making this information available, scientists from around the world who have insights into the specific types of cancer can use it to predict responses to treatment and develop and refine the algorithms that underlie the computer analysis.

Using specific cancers from radiology and pathology studies is akin to sitting in a football stadium and examining a blade of grass from the bleachers, Saltz suggested, borrowing from a phrase he’d heard at a recent panel discussion with Liron Pantanowitz from the Department of Pathology at the University of Pittsburgh Medical Center.

“What we do is we create catalogs of every blade of grass and every worm and weed,” Saltz added. “It’s a huge database problem” in which he is integrating software development.

Hannun, who has been working to help Stony Brook University earn a National Cancer Institute designation, suggested that this bioinformatics work is “a critical component of our plans” and represents an area of exceptional strength.”

Cancer bioinformatics is “one of the main pillars of our research program and it integrates well with our efforts in imaging, metabolomics, improved diagnostics and improved therapeutics,” Hannun explained.

As for his department, Saltz said Stony Brook will have its first biomedical informatics Ph.D. graduate at the end of 2017. Yanhui Liang joined Stony Brook when Assistant Professor Fusheng Wang came to Long Island from Emory. Xin Chen will graduate in May of 2018.

The doctoral program, which launched last year, has five current students and “we’re hoping to get a bigger class this year,” Saltz said. “Informatics involves making techniques for better health care,” Saltz said. People with medical degrees can do fellowship training in clinical informatics.

A resident of Manhasset, Saltz lives with his wife Mary, who is an assistant clinical professor of radiology at Stony Brook University. Over the course of the next five years, Saltz said he believes this grant will continue to allow him and his collaborators to develop tools that will help provide insights into cancer research and, down the road, into personalized cancer treatment.

TBR News Media proofreader John Broven, left, recently received an award for his work as a rhythm and blues researcher and author. Above, Broven is pictured with Cyril Vetter and Deacon John at the Nov. 16 awards ceremony. Photo by David Normand

The Three Village area is brimming with talented residents, including a renowned music researcher and author who received a prestigious award this month.

John Broven, an East Setauket resident and TBR News Media proofreader, received the Slim Harpo Music Award in the Legend category Nov. 16 in Baton Rouge, Louisiana. The awards are named after the late musician James Moore, whose stage name was Slim Harpo. The Louisiana swamp blues man’s first song was 1957’s “I’m a King Bee,” which was covered by the Rolling Stones. A few years later, Harpo had hits with “Rainin’ in My Heart” and “Baby Scratch My Back,” according to Broven, and other British bands covered his music including the Kinks and Them with Van Morrison.

“He became quite a figurehead of the British R&B boom in the early 1960s,” Broven said.

A native of Kent, England, Broven is the author of “Record Makers and Breakers,” “Rhythm & Blues in New Orleans” and “South to Louisiana: The Music of the Cajun Bayous.” In the latter two books, the author delved into Louisiana swamp blues, and in “South to Louisiana” he went into depth about Harpo’s career.

In the 1990s, while a consultant with Ace Records in London, Broven was responsible for transferring Harpo’s master tapes to CD which resulted in a three CD set release of the musician’s songs. The author said he never had the opportunity to meet Harpo due to the musician’s death at the age of 46 in 1970, a few months before Broven arrived in Baton Rouge to conduct research.

“The thousands of people who have read his books come in contact with Slim Harpo as a result of him and that is one of the reasons we chose him as our legend this year, because he’s been doing this sort of research for 40, 50 years now.”

— Johnny Palazzotto

“He was on the point of becoming an international star when he died in 1970,” Broven said.

The author said he was surprised when he was told that he was chosen for the award a few months ago.

“It’s great that Baton Rouge is preserving its history and keeping Slim’s name alive, and as far as I’m concerned, it’s an honor to be considered for this award,” he said.

Broven added that about 200 people attended the event, that also raises money for music education in schools and included a jam session with legendary rhythm and blues musicians such as Henry Gray, Carol Fran and Deacon John. Broven was introduced by Baton Rouge media entrepreneur Cyril Vetter.

Johnny Palazzotto, who is a member of the Slim Harpo Music Awards committee, said the board consists of nine members and includes Harpo’s stepson, William Gambler.

“We look for and search out people who have shown appreciation for his work, and not just for Slim’s, but Louisiana music in general,” Palazzotto said.

He said Broven was the ideal choice for the award, because the author is both a fan of Harpo’s work and Louisiana music.

“The thousands of people who have read his books come in contact with Slim Harpo as a result of him and that is one of the reasons we chose him as our legend this year, because he’s been doing this sort of research for 40, 50 years now,” Palazzotto said.

Broven is currently working on a revision of “South to Louisiana,” which will be released in 2018. The author said continuing to spread the word about regional roots music is important to him.

“The blues artists came out of the segregated South, and they did it by using their own talents,” Broven said. “It’s great to see this talent recognized not only by established musicians but also by young musicians who can learn so much from these first-generation artists.”

A recent study found that those who walk with more pace are more likely to decrease their mortality from all causes and increase their longevity.
Look beyond the number of steps you take
Dr. David Dunaief

By David Dunaief, M.D.

For most of us, exercise is not a priority during the winter months, especially during the holiday season. We think that it’s okay to let ourselves go and that a few more pounds will help insulate us from the anticipated cold weather, when we will lock ourselves indoors and hibernate. Of course I am exaggerating, but I am trying to make a point. During the winter, it is even more important to put exercise at the forefront of our consciousness, because we tend to gain the most weight during the Thanksgiving to New Year holiday season (1).

Many times we are told by the medical community to exercise, which of course is sage advice. It seems simple enough; however, the type, intensity level and frequency of exercise may not be well defined. For instance, any type of walking is beneficial, right? Well, as one study that quantifies walking pace notes, some types of walking are better than others, although physical activity is always a good thing compared to being sedentary.

We know exercise is beneficial for prevention and treatment of chronic disease. But another very important aspect of exercise is the impact it has on specific diseases, such as diabetes and osteoarthritis. Also, certain supplements and drugs may decrease the beneficial effects of exercise. They are not necessarily the ones you think. They include resveratrol and nonsteroidal anti-inflammatory drugs (such as ibuprofen). Let’s look at the evidence.

Walking with a spring in your step

While pedometers give a sense of how many steps you take on a daily basis, more than just this number is important. Intensity, rather than quantity or distance, may be the primary indicator of the benefit derived from walking.

In the National Walkers’ Health Study, results showed that those who walk with more pace are more likely to decrease their mortality from all causes and to increase their longevity (2). This is one of the first studies to quantify specific speed and its impact. In the study, there were four groups. The fastest group was almost jogging, walking at a mean pace of less than 13.5 minutes per mile, while the slowest group was walking at a pace of 17 minutes or more per mile.

The slowest walkers had a higher probability of dying, especially from dementia and heart disease. Those in the slowest group stratified even further: Those whose pace equaled 24-minute miles or greater had twice the risk of death compared to those who walked with greater speed. However, the most intriguing aspect of the study was that there were big differences in mortality reduction in the second slowest category compared to the slowest, which might only be separated by a minute-per-mile pace. So don’t fret: You don’t have to be a speed walker in order to get significant benefit.

Mind-body connection

The mind also plays a significant role in exercise. When we exercise, we tend to beat ourselves up mentally because we are disappointed with our results. The results of a new study say that this is not the best approach (3). Researchers created two groups. The first was told to find four positive phrases, chosen by the participants, to motivate them while on a stationary bike and repeat these phrases consistently for the next two weeks while exercising.

Members of the group who repeated these motivating phrases consistently, throughout each workout, were able to increase their stamina for intensive exercise after only two weeks, while the same could not be said for the control group, which did not use reinforcing phrases.

‘Longevity’ supplement may have negative impact

Resveratrol is a substance that is thought to provide increased longevity through proteins called Sirtuin 1. So how could it negate some benefit from exercise? Well, it turns out that we need acute inflammation to achieve some exercise benefits, and resveratrol has anti-inflammatory effects. Acute inflammation is short-term inflammation and is different from chronic inflammation, which is the basis for many diseases.

In a small randomized controlled study, treatment group participants were given 250 mg supplements of resveratrol and saw significantly less benefit from aerobic exercise over an eight-week period, compared to those who were in the control group (4). Participants in the control group had improvements in both cholesterol and blood pressure that were not seen in the treatment group. This was a small study of short duration, although it was well designed.

Impact on diabetes complications

Unfortunately, type 2 diabetes is on the rise, and the majority of these patients suffer from cardiovascular disease. Drugs used to control sugar levels don’t seem to impact the risk for developing cardiovascular disease.

So what can be done? In a recent prospective (forward-looking) observational study, results show that diabetes patients who exercise less frequently, once or twice a week for 30 minutes, are at a higher risk of developing cardiovascular disease and almost a 70 percent greater risk of dying from it than those who exercised at least three times a week for 30 minutes each session. In addition, those who exercised only twice a week had an almost 50 percent increased risk of all-cause mortality (5). The study followed more than 15,000 men and women with a mean age of 60 for five years. The authors stressed the importance of exercise and its role in reducing diabetes complications.

Fitness age

You can now calculate your fitness age without the use of a treadmill, according to the HUNT study [6]. A new online calculator utilizes basic parameters such as age, gender, height, weight, waist circumference and frequency and intensity of exercise, allowing you to judge where you stand with exercise health. This calculator can be found at www.ntnu.edu/cerg/vo2max. The results may surprise you.

Even in winter, you can walk and talk yourself to improved health by increasing your intensity while repeating positive phrases that help you overcome premature exhaustion. Frequency is important as well. Exercise can also have a significant impact on complications of chronic diseases, such as cardiovascular disease and resulting death with diabetes.

When the weather does become colder, take caution when walking outside to avoid black ice or use a treadmill to walk with alacrity. Getting outside during the day may also help you avoid the winter blues.

References: (1) N Engl J Med. 2000;342:861-867. (2) PLoS One. 2013;8:e81098. (3) Med Sci Sports Exerc. 2013 Oct. 10. (4) J Physiol Online. 2013 July 22. (5) Eur J Prev Cardiol Online. 2013 Nov. 13. (6) Med Sci Sports Exerc. 2011;43:2024-2030.

Dr. Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com or consult your personal physician.

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Euphorbia characias can be grown on Long Island with winter protection. Photo by Kyrnan Harvey

By Kyrnan Harvey

Alas, the allium are pretty well sold out, daffodils too I am afraid to report, from my mail-order sources like John Scheepers and Brent & Becky’s. However, if you still have the urge to invest some effort to procure some deer-proof color for spring, try the garden centers and the box stores. Possibly some choice varieties are still available, but be sure that they are not shriveled dry from a couple months of indoor heat.

With the leaves finally down, I make sure they are blown off the lawns. Lawn grasses thrive in cooler weather, so you don’t want to deprive them of a few weeks of prosperity with smothering damp leaf cover. Moreover, there is a modest pleasure derived from seeing your lawn all uniformly green again after gazing for weeks over the leafy litter, a refreshing counterpoint, more especially now, to the barren limbs of trees, the naked stems of deciduous shrubs and to the straw-colored ornamental grasses.

If you employ a lawn service, leaf blowers will typically trod over, through and onto eyes of Baptisia and peonies and Amsonia hubrichtii (commonly called blue star), blasting every scrap of humus and last May’s mulch out of the beds, exposing the naturalized and nestled-in forget-me-nots to killing exposure. In naturalistic and ecologically correct gardens it is preferable to leave fallen leaves in planted beds and where there is no lawn or paving. I even blow them into the beds, within reason, as nature’s natural mulch.

My diktat to clients, to pass onto their gardeners, is “Don’t blow the leaves in (else they will blow all of them in)” and “Don’t blow them out — of my plantings.” True, some leaves will be blown out by those arctic gusts into the lawns, and come spring cleanup you will have some work to do, removing leaves by hand where they have accumulated, but it beats the alternative of clodhoppers crushing the dormant crowns of coneflowers and columbines. I get many self-seeded perennials; but if you let your gardener blow out your beds, chances are they will blow out the baby with the bathwater.

Recently, my 10-year-old RedMax blower, a lightweight, handheld, gas-powered tool, developed carburetor issues. Rather than spend the money to have it fixed (or not), I bought a new Stihl, available at Ar-Jon Outdoor Power Equipment on Comsewogue Road in East Setauket. Very light, good power, $140.

While landscapers use the much heavier and noisier backpack blower, the Stihl is perfect for the homeowner, as indispensable to the lady gardener as to the lazy teen. If you have under a half-dozen oak trees, this is all you need. Gardeners should prefer control over leaf removal. If you have an incipient woodland garden, for example, blow all the leaves into it; they will prevent weed seeds from germinating and in two years will be earthworm-loving humus. Or blow them under the arching stems of the forsythia and into the hydrangeas.

Leaf mold is a most excellent compost. You could pile all your leaves in a hidden, out-of-the-way corner and start a large compost pile with which to annually amend your organic kitchen garden.

I have had, in a protected corner of a client’s garden, a Euphorbia characias. A common sight in sophisticated English gardens, it is an evergreen spurge native to the Mediterranean and thus not very hardy here. A year and a half ago I scattered its seeds in my home garden. Last spring they started germinating, albeit in an exposed location. The deer haven’t touched them because of the sticky sap. And this past month I have blown leaves into them, providing much needed insulation.

Kyrnan Harvey is a horticulturist and garden designer residing in East Setauket. For more information, visit www.boskygarden.com.