Stony Brook Children’s Hospital offers the most advanced pediatric specialty care in the region, which means that the smallest babies, the sickest children and the most complex pediatric traumas all get sent to Stony Brook Children’s.
Since 2010, when Stony Brook Children’s was first formed, we’ve been committed to the nearly half a million children in Suffolk County whose pediatric health care needs were underserved. Our goal was, and still is, to provide sophisticated pediatric care close to home for the many families who previously had to travel long distances.
Now with the completion and opening of our new building earlier this month, we are able to expand our capabilities to meet the growing health care needs of children and their families across Long Island.
More than 180 pediatric specialists
As the leading children’s hospital on Long Island with more than 180 pediatric specialists in more than 30 specialties, we offer a full range of medical services to support the physical, emotional and mental development of infants, children and young adults. We also can provide leading-edge care for just about every diagnosis — from a simple fracture to a kidney transplant.
Groundbreaking clinical trials
Stony Brook Children’s also provides cutting-edge research, child-sized technological innovations, clinical trials and breakthrough techniques to benefit pediatric patients as Long Island’s only children’s teaching hospital.
A child-first, family-first philosophy
The new hospital was designed with patients at the center of our thinking and planning, to promote their safety, well-being and healing. It’s the only children’s hospital on Long Island with all single-patient rooms, which allows us to combine the best practices in modern pediatric medicine with a child-first, family-first philosophy. The hospital’s design and amenities are supported by research that shows that a child-friendly environment contributes to better outcomes for children.
Each room of the new hospital includes patient, family and health care provider areas. State-of-the-art hospital beds capture and download patient information directly into the patients’ charts. Every room contains a proprietary security system, interactive televisions, in-room refrigerators, kid-focused menus as well as multicolored wall lights controlled by patients to give them a greater sense of control over their environment during what can be a frightening time for them and their families.
Other child-friendly features include separate child and teen playrooms, common areas, including an outdoor garden, and a classroom with Wi-Fi so students can keep up with their studies.
There’s also a new Ronald McDonald Family Room to offer a welcoming place for family respite, comfort and support.
Uplifting local artwork that soothes and inspires
We’ve enjoyed the support of Long Island’s artistic community in providing artwork with a Long Island nautical theme, complete with a play lighthouse and wall-sized live feed from the Long Island Aquarium. It’s truly an outstanding art collection for the entire community living in harmony with the building’s architecture and reflecting the healing mission of Stony Brook Children’s.
To learn more, visit www.stonybrookchildrens.org.
Dr. Margaret McGovern is the Knapp Chair in Pediatrics, dean for clinical affairs and Renaissance School of Medicine physician-in-chief at Stony Brook Children’s Hospital.
November is Mental Health Awareness Month and the Town of Smithtown is seizing it as an opportunity to implement a social media campaign that highlights simple activities that help boost personal resilience. From Nov. 18 to 22, the Town’s Horizons Counseling & Education Center, the Youth Bureau and the Response Crisis Center will share advice, tips and resources to Twitter, Facebook and Instagram using the hashtag #ResilientInSmithtown.
This campaign is designed to educate residents about four kinds of personal attributes that boost mental well-being: physical, mental, emotional and social.Strengthening these attributes contributes to living longer, happier lives, with a heightened ability to cope with life’s stressors.
“This is a wonderful opportunity for residents to learn how they can have more control over their own personal resiliencies and be able to guide and support family members and friends,” said Stacey Standers, Town of Smithtown Youth Bureau executive director.
Residents of all ages are encouraged to participate in the educational campaign, which relies upon easy and fun exercises that will help Smithtown residents build upon their own personal strengths.
Approximately one out of every five children in America has a diagnosable mental health disorder. Anxiety, depression and substance abuse are major issues impacting young people and their families, as well as schools and communities. Community education about the importance of bolstering one’s own personal resilience is beneficial at any age, town officials explain, and can be a vital component in maintaining mental health.
“There is a very clear and distinct correlation between childhood trauma and mental health issues and substance addiction,” said Matthew Neebe, director of Horizons Counseling & Education Center. “Problematic mental health issues experienced in childhood can very easily and often do follow individuals into maturity, creating a variety of long-term mental health issues that may cause self-medication through excessive drinking or substance abuse.”
The campaign promotes scientifically validated activities that contribute to personal well-being.
Physical resilience means the body can withstand more physical stress and heal itself faster. Mental resilience includes strengthening mental focus, discipline and will power, which is like a muscle that gets stronger the more it is exercised. Emotional resilience provokes powerful, positive emotions like curiosity or love, precisely when it’s needed the most. Social resilience strengthens from bonds with friends, family, neighbors and community.
Some of the recent posts include the following advice:
If you cannot change the situation, change your mind.
Once a situation is accepted for what it is, begin working on uncommon or creative solutions.
Humor can boost one’s mood, alleviate emotional distress and even buffer against depression. Laughter and humor improve immune response, enhance perceptual flexibility and offset the effects of stress.
Positive reframing allows you to take control of your response to a situation by reframing it into a potential growth experience.
The first step of a good plan is to define what success looks like.
The postings are part of an ongoing campaign and represent one part of this initiative.
Look for Smithtown Youth Bureau on Facebook to find the different exercises and more information about #ResilientInSmithtown.
Reducing inflammation can reduce disease risk. Stock photo
C-reactive protein can be measured to identify disease risk
By David Dunaief, M.D.
One of the most widely studied biomarkers for inflammation in our bodies is high-sensitivity C-reactive protein (hsCRP), also referred to as CRP. High sensitivity means that we can measure levels as low as 0.3 mg/L more accurately.
What is the significance of the different levels? Individuals who have levels lower than 1.0 mg/L are in the optimal range for low risk for a host of diseases that are indicated by high inflammation.
For example, with heart disease, levels of 1 to 3 mg/L represent the average risk range, and greater than 3.0 mg/L is a higher risk profile. Above 10.0 mg/L is more likely associated with other causes, such as infection and autoimmune diseases (1, 2). This biomarker is derived from the liver.
CRP is not specific to heart disease, nor is it definitive for risk of the disease. However, the upside is that it may be helpful with risk stratification, which helps us understand where we sit on a heart disease risk spectrum and with progression in other diseases, such as age-related macular degeneration, diabetic retinopathy, depression and autoimmune diseases. Let’s look at the evidence.
Stock photo
Age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness in patients over the age of 65 (3). Therefore, it is very important to help define risk stratification for this disease. In a prospective study, results showed that hsCRP levels were inversely associated with the risk of developing AMD. The group with an hsCRP greater than 3.0 mg/L had a 50 percent increased risk of developing overall AMD compared to the optimal group with hsCRP lower than 1.0 mg/L. But even more interestingly, the risk of developing neovascular, or wet, AMD increased to 89 percent in this high-risk group.
The significance of wet AMD is that it is one type of advanced-stage AMD that results in blindness. This study involved five studies where the researchers thawed baseline blood samples from middle-aged participants who had hsCRP levels measured. There were more than 2,000 participants with a follow-up as long as 20 years. According to the study’s authors, annual eye exams and lifestyle modifications, including supplements, may be able to stem this risk by reducing hsCRP.
These results reinforce those of a previous prospective study that showed that elevated hsCRP increased the risk of AMD threefold (4). This study utilized data from the Women’s Health Study, which involved over 27,000 participants. Like the study mentioned above, this one also defrosted blood samples from baseline and looked at follow-up incidence of developing AMD in initially healthy women.
The highest group had hsCRP levels over 5.2 mg/L. Additionally, when analyzing similar cutoffs for high- and low-level hsCRP, as the above trial used, those with hsCRP over 3.0 had an 82 percent increased risk of AMD compared to those with an hsCRP of lower than 1.0 mg/L.
Diabetic retinopathy
We know that diabetes affects just under 10 percent of the U.S. population and is continuing to rise. One of the complications of diabetes is diabetic retinopathy, which affects the retina (back of the eye) and is a leading cause of vision loss (5). One of the reasons for the vision loss is macular edema, or swelling, usually due to rupture of tiny blood vessels below the macula, a portion of the back of the eye responsible for central vision.
The Diabetes Control and Complications Trial (DCCT), a prospective study involving over 1,400 Type 1 diabetes patients, showed an 83 percent increased risk of developing clinically significant macular edema in the group with the highest hsCRP levels compared to those with the lowest (6). Although these results were with Type 1 diabetes, patients with Type 2 diabetes are at equal risk of diabetic retinopathy if glucose levels, or sugars, are not well controlled.
Depression
Depression is a very difficult disease to control and is a tremendous cause of disability.
Well, it turns out that inflammation is associated with depression. Specifically, in a prospective observational trial, rising levels of CRP had a linear relationship with increased risk of hospitalization due to psychological distress and depression (7). In other words, compared to levels of less than 1 mg/L, those who were 1 to 3 mg/L, 3 to 10 mg/L and greater than 10 mg/L had increased risk from 30 to 84 to 127 percent, respectively. This study involved over 70,000 patients.
How can you reduce inflammation?
This is the key question, since we now know that hsCRP is associated with systemic inflammation. In the Nurses’ Health Study, a very large, prospective observational study, the Dietary Approaches to Stop Hypertension (DASH) diet decreased the risk of both heart disease and stroke, which is impressive. The DASH diet also decreases the levels of hsCRP significantly, which was associated with a decrease in clinically meaningful end points of stroke and heart disease (8). The DASH diet is nutrient dense with an emphasis on fruits, vegetables, nuts, seeds, legumes and whole grains and a de-emphasis on processed foods, red meats, sodium and sweet beverages.
Conclusion
As the evidence shows with multiple diseases, hsCRP is a very valuable nonspecific biomarker for inflammation in the body. To stem the effects of inflammation, reducing hsCRP through lifestyle modifications and drug therapy may be a productive way of reducing risk, slowing progression and even potentially reversing some disease processes.
The DASH diet is a very powerful approach to achieving optimal levels of hsCRP without incurring potential side effects. This is a call to arms to have your levels measured, especially if you are at high risk or have chronic diseases such as heart disease, diabetes, depression and autoimmune diseases. HsCRP is a simple blood test with easy-to-obtain results.
Dr. Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com.
Enrico Scarda, owner of Danfords, with Jami Cohen at the fundraiser for her sister. Photo by Julianne Mosher
By Julianne Mosher
The Brookhaven Ballroom at Danfords was filled with hundreds of people to celebrate and support one of their own this week through the family’s bout with cancer.
Dara Cohen. photo from Dara’s GoFundMe health fund
Dara Cohen, originally of Dix Hills, has been living under the weight of cancer for years, battling Stage 4 breast, brain and lung cancer, and now friends said it has metastasized in her lower spinal cord. The actress and professional dancer works as a ballet teacher when she feels up to it, but the disease has had a lasting effect.
It was just a few months ago when Dara Cohen’s sister, Jami, who bartends at the hotel in PJ, came to work and asked her managers if they could help her create a fundraiser.
The goal was to raise $100,000 for the 46-year-old dancer, singer and actress.
“They immediately said yes,” Jami Cohen, of Port Jefferson, said. “I couldn’t ask for better people to work with.”
On Monday, Nov. 11, Danfords donated its space upstairs and an extensive menu at its buffet to the Cohen family.
“Obviously it’s an unbelievable cause,” Enrico Scarda, owner of Danfords, said, “And we do whatever we can to support our employees.”
Lamar Peters with Gail King and Shelly Cohen. Photo by Julianne Mosher
A DJ blasted music while people mingled. Lamar Peters, a tribute artist known for his Elvis, Johnny Cash and Buddy Holly impersonations, came out to play, and over 100 gifts were donated to the raffle table.
“All of us are here to unite and break course for Dara,” Dara’s father Shelly Cohen said. “We’re looking to make a difference and these people are coming out to help our daughter.”
Tickets were $40 for the three-hour event and the outcome was a huge success. Although Dara couldn’t be in attendance, she video-called in and was grateful for the response given in her honor.
Known for her popular social media posts chronicling her journey, Dara’s goal has been to help other people struggling as well.
“She’s an amazing person,” Dara’s mother Karen Deangelis, said. “Dara has made an impact on other people and has a tremendous amount of support … Hopefully we can help other people, too.”
Students and parents address the board during a standing-room only board meeting Nov. 7, after air quality issues have resurfaced at Northport Middle School. Photos by David Luces
A day that began with over 60 parents and children participating in a “sickout” protest in front of Northport Middle School ended with a public meeting later that night, where the seven-member board of education unanimously voted to begin soil testing at the school.
A packed crowd at the boarding meeting Nov. 7. Photos by David Luces
A crowd of concerned parents and community members packed into the standing room only public meeting at the William Brosnan School. Many parents voiced dissatisfaction about how the school district has been handling recent incidents with foul odors at the middle school, saying that soil and groundwater testing are long overdue.
Many people blamed illnesses, such as cancer, headaches, nosebleeds, mold infections and other serious diseases, on the school’s long history of air quality issues.
Board President David Badanes and Superintendent Robert Banzer both reiterated to the crowd that according to experts, the middle school is safe for operations.
“Since 2017, we have made major capital and personnel improvements to the school and have corrected issues found in a 65-year-old building, as well conducted environmental testing and engaged experts from the Department of Health, the Occupational and Environmental Medicine Center of Long Island and the Icahn School of Medicine,” Banzer said. “In their professional assessments, all have indicated that the middle school is safe for occupancy. Without the assurances of these professionals we would have not occupied the school.”
“In their professional assessments, all have indicated that the middle school is safe for occupancy. Without the assurances of these professionals we would have not occupied the school.”
– Robert Banzer
The district expects that soil testing and the creation of a subcommittee will quell any remaining concerns and help bring a divided community back together.
The subcommittee will be made up of 10 members, which will include board trustees, parents, district staff and professional experts. Together they will work on an analysis and come up with parameters of the soil testing.
The timetable for the subcommittee’s actions has already been established. On Dec. 12, recommendations will be given to the board identifying experts that will conduct soil testing and additional analysis. December through January, soil testing begins. January-February, assessment of soil testing results. By March, the district expects a final report, which will include recommendations given to the board.
Parent Lauren Handler called on the board to stop utilizing the services of Hauppauge-based firm J.C. Broderick, which has come under scrutiny for some of its previous reports and findings at the middle school.
She also asked for a comprehensive review of all previous testing done at the school, additional groundwater testing, cesspool testing, and investigating the environmental impact of the VA Hospital and Covanta among other things.
“If any part of this testing cannot be completed, or if testing is completed and the source of the result cannot be identified and remediated, than this building should be closed,” Handler said. “If this request cannot be met, I’m asking the superintendent and board members to step down.”
A number of speakers called on the board to consider appointing an independent broker to select the consultant and experts that will be on the committee.
Tammie Topel, a former board member who served for six years, said she previously brought up health concerns to the board.
A Northport Middle School student addresses the board Nov. 7. Photos by David Luces
“I am a former board member and when I was on the board two years ago, I requested for soil testing more than once,” she said. “Especially during one of my final board meetings, when I learned two former students had developed aplastic anemia.”
Topel, a nurse by profession, said proposals to approve soil testing at the middle school were voted down twice during her tenure.
“Why didn’t we do this two years ago?” she asked.
A number of parents also accused the board of not being up front with information about student illnesses at the school.
“I’m alarmed and disgusted by some of these things I just learned recently,” Michael Figeroura, an emergency medical technician for the New York City Fire Department and parent, said. “I find it disgusting when kids are complaining that they have headaches or smelling metallic things, they go to the nurse and all that gets done is that they check their temperature.” In addition, Figeroura criticized Timothy Hoss, Northport Middle School Principal, for his handling of the situation.
“Who tells them [the students] after he comes into the room that there’s nothing there … But miraculously 30 minutes later there’s an email, a text message and a phone call — that yes there was some type of smell in the air and that they are working on the ventilation systems,” he said. “I want something to be done, we absolutely need more testing now and later.”
He also called for better trained medical staff in the schools.
“For a nurse to check the temperature of a child after they complained about metallic smells, it is unacceptable,” Figeroura said.
Timothy Heck, an accountant and community member, was one of a number of individuals that proposed the idea of moving the middle school students to another building in the district, arguing that the district has the available space due to declining enrollment.
“I did a rough estimate myself and I figured from the administrative and operation costs, it costs around $2.5 to $5 million to keep one of the schools open,” he said. “What makes sense to me is that you could close one of the schools down and move the kids to this building or one of the grade schools.”
Heck cited a 2015 demographic study done by the district, where they projected that about 502 students were expected to be enrolled in the middle school in 2024 compared to 2007 when it had a peak of 908 students.
Similarly, at a board of education budget meeting in January, the district projected that the schools have lost nearly 1,165 students since the 2011-12 school year.
It’s unclear if board members are considering that option.
Three board of education trustees have been appointed to the committee: Vicky Buscareno, Larry Licopoli and Tom Loughran. If you are interested in being considered for the subcommittee please send an email to: [email protected].
Chronic obstructive pulmonary disease, or COPD, is the third leading cause of mortality in the United States, although it’s not highlighted much in the layman’s press (1).
COPD is an umbrella term that includes emphysema, chronic bronchitis of more than three months for two consecutive years and/or chronic obstructive asthma. It is an obstructive lung disease that limits airflow. The three most common symptoms of the disease involve shortness of breath, especially on exertion, production of sputum and cough. This disease affects 6.7 percent of the U.S. population (2).
It tends to be progressive, meaning more frequent and severe exacerbations over time. Since it is a devastating and debilitating chronic disease with no cure, anything that can identify and prevent COPD exacerbations, as well as comorbidities (associated diseases), is critically important.
What are the traditional ways to reduce the risk of and treat COPD exacerbations? The most important step is to stop smoking, since 80 percent of COPD is related to smoking. Supplemental oxygen therapy and medications, such as corticosteroids, bronchodilators (beta-adrenergic agonists and anticholinergics) and antibiotics help to alleviate symptoms (3).
One of the underlying components of COPD may be chronic inflammation (4). Therefore, reducing inflammation may help to stem COPD exacerbations. There are several inflammatory biomarkers that could potentially help predict exacerbations and mortality associated with this disease, such as interleukin-6 (IL-6), C-reactive protein (CRP), leukocyte (white blood cell) count and fibrinogen (a clotting factor of the blood).
How do we reduce inflammation, which may contribute to exacerbations of this disease? Some drugs, such as statins, work partially by reducing inflammation. They may have a role in COPD. Lifestyle changes that include a high-nutrient, anti-inflammatory diet and exercise may also be beneficial.
Let’s look at the evidence.
Biomarkers for inflammation
In a population-based study with over 60,000 participants, results show that as three biomarkers (CRP, leukocyte count and fibrinogen) were elevated, the risk of COPD exacerbation increased in a linear manner (5). In other words, the risk of frequent exacerbation increased 20, 70 and 270 percent within the first year as the number of elevated biomarkers increased from one to three, compared to patients who did not have biomarker elevations.
As time progressed beyond the first year of follow-up, risk exacerbation continued to stay high. Patients with all three biomarkers elevated for longer periods had a 150 percent increased risk of frequent exacerbations. These predictions were applicable to patients with stable and with mild COPD.
In an observational study, results showed that when the biomarker IL-6 was elevated at the start of the trial in stable COPD patients, the risk of mortality increased almost 2.7-fold (6). Also, after three years, IL-6 increased significantly. Elevated IL-6 was associated with a worsening of six-minute walking distance, a parameter tied to poor physical performance in COPD patients. However, unlike the previous study, CRP did not show correlation with increased COPD exacerbation risk. This was a small trial, only involving 53 patients. Therefore, the results are preliminary.
These biomarker trials are exciting for their potential to shape treatments based on level of exacerbation risk and mortality, creating more individualized therapies. Their results need to be confirmed in a randomized controlled trial (RCT). Many of these biomarkers mentioned in the two trials are identifiable with simple blood tests at major labs.
Statin effect
Statins have been maligned for their side effects, but their efficacy has been their strong suit. An observational trial showed that statins led to at least a 30 percent reduction in the risk of COPD exacerbations, with the effect based on a dose-dependent curve (7). In other words, as the dose increased, so did the benefit.
Interestingly, even those who had taken the statin previously saw a significant reduction in COPD exacerbation risk. The duration of statin use was not important; a short use of statins, whether presently or previously, had substantial benefit. However, the greatest benefit was seen in those who had been on a medium to high dose or were on the drug currently. The researchers believe that the mechanism of action for statins in this setting has to do with their anti-inflammatory and immune-modulating effects. This was a retrospective (backward-looking) study with over 14,000 participants. We will need a prospective (forward-looking) study and an RCT to confirm the results.
Exercise
stock photo
Exercise is beneficial for almost every circumstance, and COPD is no exception. But did you know that a pedometer might improve results? In a three-month study, those with mild COPD were much more successful at achieving exercise goals and reducing exacerbations and symptoms when they used pedometers, compared to the group given advice alone (8). Pedometers gave patients objective feedback on their level of physical activity, which helped motivate them to achieve the goal of walking 9,000 steps daily. This is a relatively easy way to achieve exercise goals and reduce the risk of COPD exacerbations.
When exercising, we are told to vary our exercise routines on regular basis. One study demonstrates that this may be especially important for COPD patients (9). Results show that nonlinear periodization exercise (NLPE) training is better than traditional routines of endurance and resistance training in severe COPD patients. The goal of NLPE is to regularly alter the time spent working out, the number of sets, the number of repetitions and the intensity of the workout on a regular basis.
This study was randomized, involved 110 patients and was three months in duration. Significantly more severe COPD patients achieved their exercise goals using NLPE than the traditional approach. The group that used NLPE also had an improved quality of life response. The researchers believe that compliance with an NLPE-type program is mostly likely going to be greater because patients seem to enjoy it more.
Chronic inflammation may play a central role in COPD exacerbation. Nonspecific inflammatory biomarkers are potentially valuable for providing more personalized approach to therapy. Drugs that can control inflammation, such as statins, show promise. But don’t forget the importance of lifestyle changes, such as quitting smoking and committing to an exercise regimen that is varied and/or involves the use of a pedometer. And potentially a high-nutrient, anti-inflammatory diet will also contribute positively to reducing the frequency and severity of COPD exacerbations.
References:
(1) Natl Vital Stat Rep. 2011 Dec.;59(10):1-126. (2) cdc.gov. (3) N Engl J Med. 2002;346:988-994. (4) www.goldcopd.org. (5) JAMA. 2013;309:2353-2361. (6) Respiratory Research. 2013;14:24. (7) Am J Med. 2013 Jul;126:598-606. (8) ATS 2013 International Conference: Abstract A1360. (9) Am J Respir Crit Care Med. 2013; online Feb. 28.
Dr. Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com.
After two years of extensive renovation and with generous support from New York State, Cold Spring Harbor Laboratory’s historic Demerec Laboratory was reborn as a state-of-the-art research facility. Governor Andrew Cuomo cut the ribbon for the building’s reopening on Oct. 30, celebrating how the state will benefit from this new chapter in CSHL research.
“It’s good for Long Island, it’s good for the economy, but also it is doing work that I believe will improve the quality of life for thousands and thousands of people. I believe this work will actually save lives and there is nothing more important than that,” Governor Cuomo said during his visit. “That is the work that the people in this facility are dedicated to and God bless them for that. The state is honored to be playing a small role today.”
The Demerec Laboratory, home to four Nobel laureates, has been both a bastion and compass point for genetics research in New York and the world. Its new research will focus on taking a more holistic approach to treating cancer and the disease’s impact on the entire body.
According to the CSHL’s website, the new center “will enable newly developed compounds to be refined by world-leading chemists to develop next-generation therapies. This research will form a basis for collaboration with private foundations and pharmaceutical companies, while advancing the development of new drugs.
In addition, the center will support ongoing research activities aimed to develop therapeutics for breast cancer, leukemia, autism, obesity, diabetes and lung cancer. The primary goal of such research activities will include the development of advanced drug compounds targeting underlying biological pathways.”
To prepare the Demerec building for 21st-century science, it had to be gutted, with extensive renovations of the basement and interior, while leaving the historic 1950s brutalist exterior largely unchanged.
“We really challenged ourselves to preserve the history of the building as much as possible,” said Centerbrook design firm architect Todd E. Andrews, who planned the renovation.
The result is a modern facility uniquely designed for a scientific approach that considers disease not as a stand-alone subject of study but as a complex system that focuses on the patient.
“Too often [scientists] are not looking at the patient and the system of the patient … even though there are obvious signs that we should be looking,” said Dr. Tobias Janowitz, one of the next generation of Demerec Lab scientists and research-clinicians dedicated to rethinking cancer medicine.
Other Demerec researchers will include Nicholas Tonks, who investigates relationships between diabetes, obesity and cancer, and Linda Van Aelst, a neuroscientist who is interested in how sleep and signals from the brain may be impacted by cancer. Semir Beyaz, who studies how a patient’s nutrition can affect cancer treatment, will also join the team.
While the Demerec Laboratory’s faculty hasn’t been finalized, the researchers will be working alongside the rest of the CSHL community — including 600 scientists, students and technicians — to create a distinctly collaborative and cross-disciplinary culture.
Governor Cuomo called the Demerec building and the larger CSHL campus “hallowed ground for scientific research,” after dedicating $25 million in 2017 toward the $75 million renovation and said he is confident the space and its scientists will deliver a new wave of scientific progress.
“We invested over $620 million statewide in life sciences with $250 million in Long Island alone in biotech. Why? Because we believe that is an economic cluster that is going to grow and that is going to create jobs and it already is,” the governor said. “I believe Long Island is going to be the next Research Triangle.“
Renovating a single research facility may seem like a small step toward the state’s goal, but this particular building has made Long Island a scientific hot spot once again.
“While the Demerec building is comparatively smaller than larger projects that the governor has initiated … it is arguably one of the most productive buildings in all of science,” said CSHL President and CEO Bruce Stillman. “This renovation allows us to really think about where the Lab will take things next. It will have, I hope, a global impact on the research community, especially in the biomedical sciences.
Community gathers at Northport Middle School for 'sickout' . Photo by Donna Deddy
November 7 should have been a normal school day at Northport Middle School, according to a letter that the district sent out to its families on Tuesday. However, community members organized a protest called a “sickout” Thursday morning because of ongoing concerns that date back decades with air quality issues in the building.
Most recently, a heating, ventilation and air-conditioning system installed in 2018 is being blamed for causing what the district calls “unpleasant odors” in certain wings of the building. That situation, the district states, has been addressed. After inspections, it found no visible cause for the problem. It has attributed the odor to heating elements being used for the first time and debris captured in drip plates on the building’s roof. No evidence of carbon monoxide, volatile organic compounds, airborne particulates or mold was found in its air sampling, the district said.
However, children were complaining of “dead animal smells” that caused headaches, coughing and vomiting, and after decades of ongoing health concerns, parents, retired teachers and other community members are calling for stronger action.
“The building needs to be closed,” Tara Mackey said. “No question about it.”
“The building needs to be closed, no question about it”
– Tara Mackey
Her child’s blood work, she said, identified a clear pattern of carbon monoxide exposure that spiked during school sessions and cleared during school vacations. The family ultimately moved last June in response to the concern after what she calls a two-and-a-half-year ordeal.
More than 600 students attend Northport Middle School on Middleville Road. The district did not respond to repeated requests for information on the number of students that have fallen ill from the latest air quality concerns at the school. People interviewed for this report and state on Facebook that their children in the past have suffered with nose bleeds, chronic coughs to the point of vomiting, asthma and headaches.
Parents, who have conducted their own informal study, have identified 18 students who were diagnosed over the last 10 years with leukemia, lymphoma and aplastic anemia, all rare diseases often caused by environmental exposures. Four children, they say, have died.
New York State Assemblyman Andrew Raia (R-East Northport) has asked the New York State Department of Health to conduct a longitudinal study in response to the concerns in a Nov. 1 letter. Earlier this year, lawmakers requested studies, when they learned that five recent Northport High School graduates from the same graduating class were diagnosed with blood cancers. That study is ongoing.
Northport Middle School renovated wings of its school in 2018 to address ongoing air quality issues. Photo from Northport-East Northport School District
“We are continuing our review of cancers reportedly developed among former students of the Northport-East Northport Union Free School District,” said Erin Hammond, press officer for the state health department. “We look forward to sharing our findings with the community in early 2020. Any further investigation will depend on the findings of the ongoing review. Again, genetics, lifestyle choices and environmental exposure histories are all potential contributing factors for cancer and are taken into consideration in incidence investigations.”
Former teachers have also reportedly fallen ill. John Kobel said that he has skin cancer, prostate cancer, heavy metal contamination and occupationally induced respiratory disease after working in the science classroom in the middle school, where he said chemicals were improperly stored in a closet cesspool. The sinks’ drains, he said, also lacked traps as code dictates. The former teacher surveyed about 200 to 300 staff members and learned that 33 former teachers also have cancer.
Government officials have said in telephone interviews that they want to avoid public hysteria.
But the lack of adequate oversight has been a concern. Some people say that there is a cover-up. They say that district officials have not completed shallow and deep soil and groundwater testing on-site or published copies of the inspection reports for two 4,000-gallon underground storage tanks that store the diesel fuel for the districts buses, which refuel at the same location. They also wonder, when prompted, why the district decided against comparing the reasons for health office visits at the district’s two middle schools. They worry about underground plumes and exhaust from idling buses at the district depot on-site. There’s also been concerns about mold in the building.
The site is also roughly two miles from the Covanta plant, a facility that burns 750 tons per day of municipal waste from residential, commercial and industrial sources. The facility, which began operations in 1991, also incinerates the combustible portion of construction and demolition (C&D) debris, light industrial waste, shredded tires, sewage treatment plant sludge and other nonhazardous industrial waste streams on-site as approved by the New York State Department of Environmental Conservation on a case by case basis.
Covanta Huntington, also known as the Huntington Resource Recovery Plant, is a major source of air emissions in the region and is considered among the largest in New York. The region’s air quality for oxides of nitrogen and VOCs exceed safe standards, which causes asthma and other respiratory ailments. But the facility’s emissions are within all permissible limits set for the plant by the DEC.
“It’s just not possible for Covanta to be a factor,” James Regan, media relations director. “Other schools, the Fifth Avenue School, Bellerose Avenue and Commack Union Free Schools are also close by, and they have no odor complaints there.”
Prevailing winds, Regan also said, blow its emissions in different directions. The company, he said, will gladly host a site tour to show community members how the facility works and cannot possibly be the cause.
The Suffolk County Department of Health states that schools fall under the state’s jurisdiction. The state department of health states that “local school districts are responsible for monitoring air quality in its schools.” The state health department added that it’s available for technical assistance, if requested.
Through its public relations firm, the district states that it has reached out to the state for assistance.
In the past year, the school has changed its refueling schedule for buses on site, renovated wings of the school, removed hazardous material stored on-site below classrooms and installed new ventilation equipment, among other actions taken.
The district stated in its Nov. 4 letter that the school board will discuss and approve more testing and form a committee to further review the situation at its Nov. 7 board meeting. The meeting will be held at 7 p.m. at W.J. Brosnan School, 158 Laurel Ave., Northport.
The district has documented the actions it’s taken and its correspondence with the public and teachers union on its website.
The Facebook page Close Northport Middle School Long Island, New York states that more than 50 people signed up to attend the “sickout.” They are calling on kids to wear blue to school, if they plan on attending classes to support the cause.
Lowering sodium intake may have far-reaching benefits, and it is certainly achievable. Stock photo
High sodium: potassium ratio increases cardiovascular risk
By David Dunaief, M.D.
Dr. David Dunaief
We need sodium in our diets in modest amounts; however, many Americans overconsume it. Meanwhile, potassium, which we also need, is underconsumed.
More than 90 percent of people consume far too much sodium, with salt being the primary culprit (1). Sodium is found in foods that don’t even taste salty. Bread and rolls are the primary offenders. Other foods with substantial amounts of sodium are cold cuts and cured meats, cheeses, pizza (which has both bread and cheese), fresh and processed poultry, soups, meat dishes, pastas and snack foods. Foods that are processed and those prepared by restaurants are where most of our consumption occurs (2).
By contrast, only about 2 percent of people get enough potassium from their diets (3). According to one study, we would need to consume about eight sweet potatoes or 10 bananas each day to reach appropriate levels. Why is it important to reduce sodium and increase potassium? A high sodium-to-potassium ratio increases the risk of cardiovascular disease by 46 percent, according to the study, which looked at more than 12,000 Americans over almost 15 years (4). In addition, both may have significant impacts on blood pressure and cardiovascular disease.
To improve our overall health, we need to tip the sodium-to-potassium scales, consuming less sodium and more potassium. Let’s look at the evidence.
Reduced sodium
Two studies illustrate the benefits of reducing sodium in high blood pressure and normotensive (normal blood pressure) patients, ultimately preventing cardiovascular disease, including heart disease and stroke.
The first used the prestigious Cochrane review to demonstrate that blood pressure is reduced by a significant mean of −4.18 mm Hg systolic (top number) and −2.06 mm Hg diastolic (bottom number) involving both normotensive and hypertensive participants (5). When looking solely at hypertensive patients, the reduction was even greater, with a systolic blood pressure reduction of −5.39 mm Hg and a diastolic blood pressure reduction of −2.82 mm Hg.
This was a meta-analysis (a group of studies) that evaluated data from randomized clinical trials, the gold standard of studies. There were 34 trials reviewed with more than 3,200 participants. Salt was reduced from 9 to 12 grams per day to 5 to 6 grams per day. These levels were determined using 24-hour urine tests. The researchers believe there is a direct linear effect with salt reduction. In other words, the more we reduce the salt intake, the greater the effect of reducing blood pressure. The authors concluded that these effects on blood pressure will most likely result in a decrease in cardiovascular disease.
In the second study, a meta-analysis of 42 clinical trials, there was a similarly significant reduction in both systolic and diastolic blood pressures (6). This meta-analysis included adults and children. Both demographics saw a reduction in blood pressure, though the effect, not surprisingly, was greater in adults. Interestingly, an increase in sodium caused a 24 percent increased risk of stroke incidence but, more importantly, a 63 percent increased risk of stroke mortality. The risk of mortality from heart disease was increased as well, by 32 percent.
In an epidemiology modeling study, the researchers projected that either a gradual or instantaneous reduction in sodium would save lives (7). For instance, a modest 40 percent reduction over 10 years in sodium consumed could prevent 280,000 premature deaths. These are only projections, but in combination with the above studies they may be telling. The bottom line: Decrease sodium intake by almost half and increase potassium intake from foods.
Potassium’s positive effects
When we think of blood pressure, sodium comes to mind, but not enough attention is given to potassium. The typical American diet doesn’t contain enough of this mineral.
In a meta-analysis involving 32 studies, results showed that as the amount of potassium was increased, systolic blood pressure decreased significantly (8). When foods containing 3.5 to 4.7 grams of potassium were consumed, there was an impressive −7.16 mm Hg reduction in systolic blood pressure with high blood pressure patients. Anything more than this amount of potassium did not have any additional benefit. Increased potassium intake also reduced the risk of stroke by 24 percent. This effect was important.
The reduction in blood pressure was greater with increased potassium consumption than with sodium restriction, although there was no head-to-head comparison done. The good news is that potassium is easily attainable in the diet. Foods that are potassium-rich include bananas, sweet potatoes, almonds, raisins and green leafy vegetables such as Swiss chard.
Lowering sodium intake may have far-reaching benefits, and it is certainly achievable. We need to reduce our intake and give ourselves a brief period to adapt — it takes about six weeks to retrain our taste buds, once we reduce our sodium intake. We can also improve our odds by increasing our dietary potassium intake, which also has a substantial beneficial effect, striking a better sodium-to-potassium balance.
Dr. Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com or consult your personal physician.
Community gathers at the Old First Church in Huntington to celebrate those who have conquered addiction and remembering those who have been lost.
The Town of Huntington Opioid and Addiction Task Force invited residents to join a special program Oct. 28 at the Old First Presbyterian Church in Huntington celebrating those who have conquered addiction and remembering those who have been lost.
The program, “A Recovery Event: Celebrating Hope in Huntington,” featured first-hand accounts from those who have conquered addiction, information about local prevention, treatment and recovery programs, and a stirring performance by the Old First Church Sanctuary Choir.Sharon Richmond shared her story about her son Vincent.The ceremony was dedicated to his honor. (See page A5 for her story.)
“Huntington, like every other community in America, has been hit hard by the opioid crisis,” said Huntington Councilman Mark Cuthbertson (D), who sponsored the program with the task force. “We created this event to show that there is a cause for hope and that in fact that there are thousands of local residents who have found a path to recovery,”
The event drew more than 100 people to the Old First Church. A highlight of the evening was a candlelight circle to celebrate, honor and remember those who were lost as a result of their addiction.
Created by a town board resolution in December 2017, the Opioid and Addiction Task Force includes local health care professionals, educators and community leaders. It works to unify, support and strengthen prevention, treatment and recovery efforts within the town. Its goals include reducing the incidence of substance abuse, promoting timely access to care for consumers and their families, creating environments conducive to recovery and reducing the stigma associated with substance use disorders.
“Many of our families have been greatly affected — their lives changed forever after losing a loved one to addiction,” Cuthbertson said. “We know that substance abuse is preventable, addiction is treatable and recovery works.”
The town is hanging resource information posters around town.
“Somebody is waiting for you to come to them,” said Stephen Donnelly, who has sponsored different opioid services in the past. He encourages people to ask people impacted:“How can I help you?”
For Treatment Referral List contact the 24/7 hotline 631-979-1700. Help is a phone call away.
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