CLOSE
Tags Posts tagged with "Covid 19"

Covid 19

by -
0 409
Tadanori Koga is the third from the right, Maya Endoh is the fourth from the right (all in the front row). Photo courtesy Elena Stephanie.

By Daniel Dunaief

Hoping to take a page out of nature’s playbook, a married couple in the Department of Materials Science and Chemical Engineering at Stony Brook University is studying a structure that could prevent the spread of pathogens on the surface.

Before the pandemic started, Research Professor Maya Endoh and Associate Professor Tadanori Koga were exploring how anti microbial coatings controlled pathogens on the molecular scale. With the pandemic, they became more focused on ways to prevent pathogens from causing infections after people came into contact with contaminated surfaces.

Working with researchers from Oak Ridge National Laboratory, North Carolina Agricultural and Technical State University and the University of Tennessee Health Science Center, the team received $12 million over three years as a part of the Department of Energy’s Biopreparedness Research Virtual Experiment initiative, which supports multidisciplinary research efforts designed to strengthen precautionary measures against infectious disease outbreaks. Koga and Endoh received a subcontract of $1.2 million from the Oak Ridge National Laboratory which runs until December 2026.

This kind of study, along with other funded research on the spread of pathogens, could be “important to prevent the next pandemic,” said Endoh. She added that this kind of work could not only help reduce the danger from another potential pandemic, but could also help cut down infections from other common health threats.

The research plans to explore the physical and chemical interactions that occur when bacteria come in contact with a material surface.

To develop surface coatings that might resist the spread of disease-carrying pathogens, Koga and Endoh are turning to an insect that will be even more abundant than usual this year. For the first time since 1803, the 13-year and 17-year cicadas will emerge at the same time.

Koga and Endoh, however, are less focused on their prevalence or their loud noises than they are on their wings, which resist bacteria and may also provide protection against viruses and fungi, as something about their nanostructure disables these pathogens.

“We want to learn from nature,” said Endoh. “As material scientists, we want to mimic this structure.”

Their method of killing bacteria is to facilitate bacterial attachment to nanopattern surfaces. They are targeting surfaces that are constantly and directly exposed to pathogens, such as medical devices, tools and sensors.

Their computational results suggest that a nanopatterned surface can puncture a bacterial outer membrane. These scientists can not specify the time range clearly, which is something they are pursuing with the awarded project.

“We are targeting the surfaces which are constantly and directly exposed to pathogens, such as medical devices, tools and sensors,” Koga and Endoh explained in an email.

Structural defense

The structure of the cicada wings have nanopillars that are about 100 nanometers tall and that are separated by about 100 nanometers from each other. The nanopillars they plan to use have a height of 10 nanometers, a diameter of 50 nanometers and a space between adjacent cylinders of 70 nanometers.

By creating a similar structure with polymers, the Stony Brook scientists will attempt to manufacture materials that provide the same resistance.

They will optimize the geometric parameters of the nanostructure, especially its height and interpillar spacing, to create different nano topographies, including nanopillars, nanowalls, nanospikes and nanodomes.

They are starting their work with the bacteria E. coli and will use computational approaches to optimize surface geometric parameters, bacteria-substrate interactions and bacterial wall stiffness to create a robust structure-guided antimicrobial surface.

They will use polystyrene block polymers and are planning to use different ingredients such as biopolymers. They believe the ingredients can be varied.

According to their recent molecular dynamics simulations mimicking experimental conditions, attractive interactions promote additional membrane attachment, pulling the membrane taut against the pillars and creating tension that ruptures the cell wall. The rupture occurs at the high curvature regions near the edge of the pillars.

Surfaces coated by polymers would likely require periodic coating applications. The scientists treat those polymers with a three-dimensional link to improve the mechanical property. They also apply atomic-thin scale metal layers to make the surface more durable.

In collaboration with Brookhaven National Laboratory, they are trying to determine how to make this kind of pattern with different substances.

“We don’t know what shape is the best [for various pathogens], what size is the best and what spacing is the best,” said Koga.

Benefits of collaboration

Koga and Endoh appreciate the opportunity to collaborate with a range of talented scientists at other institutions.

“Luckily, we have a lot of collaborators,” Endoh said.

Koga and Endoh became a part of a bigger collaboration when they worked with Jan-Michael Carrillo and Bobby Sumpter at Oak Ridge National Laboratory, who started this project.

“This is a nice step, but it’s not the end,” said Koga. The next step is to “create a real material.”

Lifelong collaboration

Koga and Endoh met in their native Japan. Koga is from Kyushu, while Endoh grew up in Sendai, which was the epicenter of the Tōhoku earthquake in 2011, which created the tsunami at the Fukushima nuclear power plant.

They came to the United States when Koga wanted to become a postdoctoral researcher for a two year assignment at Stony Brook. Over 27 years, and four children later, they are still at Stony Brook.

Over the years, Endoh juggled motherhood and a postponed PhD, which she eventually received from Kyoto University.

Koga enjoys watching Japanese players in Major League Baseball and is a fan of Dodgers superstar Shohei Ohtani. A “soccer mom,” Endoh enjoys cooking and playing the violin. The couple hikes in the summer and skis in the winter.

As for their own protective measures during the pandemic, Koga and Endoh regularly washed their hands, although they didn’t use Purell or other special wipes to clean any surfaces. 

by -
0 609
Photo from Deposit Photos

By Daniel Dunaief

In a nod to the herd immunity from a combination of illnesses and vaccinations in the population, the Centers for Disease Control and Prevention is widely expected to reduce the recommended number of days of isolation after a positive test to one day from five days.

Even as most of the population has returned to a normal life after the pandemic — toughing through colds with relatively mild symptoms at work and staying home, for the most part, when symptoms become severe — the CDC had urged Americans to remain isolated for five days.

“Covid has diminished as a real threat for the majority of people,” said Dr. Sharon Nachman, Chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital. “The responsiveness between vaccinations and multiple events [such as infections] is reasonable to prevent hospitalization and death in most people.”

In addition, Covid treatments, such as Pfizer’s Paxlovid, have become effective in reducing the severity and duration of symptoms.

The CDC likely couldn’t have provided such guidance a year ago, but, for most people, the consequence of contracting the virus that altered the course of life for people for several years, has been less problematic for their health, doctors said.

Despite ongoing illnesses and symptoms, people have become less likely to test for Covid.

“Insurance companies used to pay for eight per month, but now, people just buy one [test box] at a time,” said Michael DeAngelis, the owner of Village Chemist in Setauket.

Dr. Sunil Dhuper, chief medical officer at Port Jefferson’s St. Charles Hospital, understood the CDC’s decision, with an important warning.

“The rationale behind changing the timing of isolation guidelines is based on looking at the evolving severity of cases,” Dhuper said.

“People who are younger get more mild levels of illness and recover,” he added.

Concerns for the elderly

“The disease is beginning to behave more and more like other respiratory viruses, but we are not there yet,” Dr. Dhuper cautioned, particularly for those who are over 65.

Hospitalization for people who contract Covid is 11.2 per 100,000 for people over 65, compared with 6.9 per 100,000 in the week ending Feb. 10, according to data from the Centers for Disease Control and Prevention. 

The mortality for those over 65 from Covid is higher than for the flu, Dr. Dhuper said.

“We have to be a little cautious, sending a message to the community that you can continue to do what you want to do,” Dr. Dhuper said. “When they are around the elderly” people, particularly those who might have symptoms even if they haven’t been tested, should consider wearing masks or keeping their distance.

The incidence of Covid, among other illnesses, climbed after the December holidays and the start of 2024, as people traveled to visit with family or on vacations. Those numbers have come down, although the upcoming spring break from secondary schools and colleges raises the possibility that illnesses could climb again, doctors predicted.

Be careful of grandkids

While the public may not want to hear it, Dr. Dhuper expected that it might take another five years before Covid reaches a comparable level of potential risk to the elderly as the flu, which could also present a risk to people’s health.

Dr. Dhuper urged those who have symptoms to test themselves for Covid. Even if they don’t isolate themselves for more than 24 hours, they should be cautious around vulnerable groups.

Dr. Dhuper’s advice to grandparents is to “be careful when you’re around your grandkids, because they are like petri dishes, harboring tons of infections.”

While for many people in the community, Covid has become like white noise, it’s still causing medical problems and leading to some hospitalizations, the St. Charles doctor added.

Any change in isolation guidance from the CDC should come with an asterisk that “yes, we are changing the guidelines, but people should still exercise precautions,” Dr. Dhuper said.

Vaccination research

Amid discussions related to vaccines, Dr. Nachman added that several compelling papers have demonstrated that people who are up to date on their vaccines, including flu, are at lower risk for dementia.

The link between vaccinations and overall brain health is unclear, and it is possible that people who receive vaccines also have a lifestyle that reduces the risk of developing dementia.

“We have an aging population in New York, particularly on Long Island,” said Dr. Nachmman. “If we want to keep them healthier longer, getting appropriate medical care, including vaccines, is probably helpful.”

by -
0 517

By Daniel Dunaief

For the first time since May 2023, Brookhaven National Laboratory required masks on site at its facility starting on Jan. 8, as the rate of hospital admissions for the virus that caused the pandemic climbed.

Following the Safer Federal Workforce Task Force, BNL, which is a Department of Energy-sponsored site, reinstituted the mask policy once Covid admissions climbed above 20 per 100,000 people in the county, as determined by the Centers for Disease Control and Prevention data.

The CDC level rose to 24.8 on the evening of Jan. 5 and the lab re-implemented its mask requirement on the following Monday. Area doctors said they’ve seen an increase in illnesses tied to Covid, particularly after people traveled during the December holidays.

“We’ve seen a lot more Covid,” said Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital. 

Dr. Nachman said people who are talking to friends and neighbors are hearing regularly about those who are sick with Covid.

Stony Brook University Hospital is not requiring masking at all times. The hospital is recommending that people consider wearing masks. Medical staff entering patient rooms are wearing them.

People walking into the hospital will see “more people wearing masks” in general, she added. In addition to Covid, hospitals in the area are also seeing a “huge amount of flu,” Dr. Nachman said.

 

by -
0 390
METRO photo

By Leah S. Dunaief

Leah Dunaief

COVID got me again. This second time around makes me angry, which is probably irrational. I mean, really, I paid my dues, I succumbed like almost everyone else a couple of years ago, and I feel that should be that. Also, I did everything I was supposed to do. I was vaccinated again in the middle of October this past year and felt pretty immune, although I know the vaccine doesn’t prevent the disease, just makes it less severe if it hits. Still, I felt relatively protected and didn’t bother wearing a mask when in a group. I won’t make that mistake again.

I did take Paxlovid this time, as I had the first time, and perhaps my symptoms were less acute. This onset was a little different. Instead of the painful sore throat in the beginning, I developed a dripping nose and assumed I was getting a simple head cold. Then I got quite stuffy and began to cough and to run a low grade fever. I stayed out of the office, finally donned a mask and bought a test kit. The first test I took was negative, but the next day I tested positive, and I have been home since then.

I am sharing these details in the hope that they may be helpful for those who are experiencing COVID presently or who should be alerted now to the clear and present danger. Fortunately, I am again testing negative, but the weather is uncooperative at 17 degrees. The extreme cold and dry air is not recommended for a newly recovered respiratory system, and so I remain home for now. But I can reveal some more specifics that might be of interest.

Neurological aspects were less pronounced this second time around. The sore throat was less sore and lasted for a shorter period of time, I didn’t lose my sense of taste either time, and while the cough continues, it seems less frequent during this home stretch. But according to what I read, post COVID fatigue is worse, and I can confirm that. I haven’t slept this many hours each day since I was a teenager. Napping is also a help. I have craved hot soup, and little else, throughout these past few days. Blessings on my friends and neighbors, who have provided me with an endless supply, from homemade chicken broth to the store bought wonton variety. I am also drinking smoothies made up of fruits and especially dark green leafy vegetables, like bok choi and baby kale and arugula. This particularly helps ward off dehydration. And while I have lost a couple of pounds, this is not the preferred way to diet.

There are some studies on patients who have had COVID more than once. Experts are still unsure about how damaging that might be, if at all. New variants, like JN.1, and periodic upticks keep the virus a current threat. There are at least 1200 covid-related deaths each week, and in the last week of December, nearly 35,000 Americans were hospitalized with COVID. No one seems to know if repeated exposure to the coronavirus increases the risk of Long Covid.Those who were hospitalized with the first round of COVID were more likely to have a severe second bout. That is well established. Lingering symptoms, like fatigue, shortness of breath and brain fog may also persist, especially after a difficult first attack. But evidence is still unclear that links repeated infections with Long COVID.

So what to do next?

We should all forego our complacency, and actively try to avoid COVID-19, even though the disease appears to be less severe for most. We really don’t know the long term effects of repeated infection. That means going back to basics: washing hands often, avoiding crowds, if possible, staying home if ill, using Paxlovid, which has been highly successful in moderating the virus, and especially returning to wearing masks. No one wants to be mildly ill or to increase the health risk for others.

by -
0 443

Some parents had advocated to make the pandemic-era reprieve permanent

Public domain photo

Regents exam scores will account for 10% of student grades this year in Three Village Central School District, despite calls to extend a COVID-19 pandemic-era policy that only includes the scores when they improve student course grades.

The decision, which came after robust discussion and disagreement among board members at their Nov. 29 meeting, goes along with the recommendation of a district committee to include the scores at 10% of the final grade — down from the 12% that was policy before the pandemic reprieve.

Freshman board members Karen Roughley and David McKinnon spoke openly against including scores in all student grades, particularly because New York State does not mandate doing so for all districts, and they said it could disadvantage Three Village students who struggle with test anxiety, have special needs or experience a personal catastrophe before the test date.

“Using the Regents scores would decrease a student’s GPA and put them at a disadvantage against all the other students in the state who do not have it included, in applying for colleges and scholarships,” Roughley said.

The State Education Department’s website states it “does not require nor recommend the inclusion of Regents exam scores in the computation of final course averages,” and rather leaves it up to each district to decide.

McKinnon called this approach a failure of leadership. “The state doesn’t stand behind their test,” he said. “The state makes the test, they pass it out, they grade it, but then they have no effective policy on what we should do with that test.”

After parents — especially those of children with special needs — spoke out last spring, the previous board voted to extend the so-called Do No Harm policy through the end of the 2022-2023 school year with the caveat that a permanent decision should come this fall.

In recommending inclusion of Regents scores at 10%, the committee suggested students may not take the exams as seriously if the scores don’t count toward a course grade.

Trustee Vincent Vizzo, a former teacher and administrator who has a long affiliation with Three Village and said he was part of writing Regents exams in the past, admitted he was not a fan of the state tests and understands they can hurt students who do not do well. “I have very mixed opinions right now,” he said. “But if a committee of educators are saying that they want to keep the percentage, then I don’t think the board should micromanage and decide against what the committee is saying.”

Board president Susan Rosenzweig also expressed mixed feelings, saying she believes Do No Harm makes philosophical sense, but that there can be valuable information garnered from all students “meaningfully engaging in the assessments.”

When the remaining board members echoed Vizzo’s desire to defer to the committee of professional educators, Rosenzweig attempted to broker a compromise by suggesting the board include the scores at 5% instead of 10%, which she said was her “comfort level,” but only trustee Jeffrey Kerman expressed interest in changing the percentage, saying he would vote for either 5% or 10%.

Seeing no appetite for middle ground, Rosensweig cast the deciding vote with an audible sigh. “Because I guess it’s not going to go any other way,” she said.

by -
0 3471

Three Village school board discusses cell phones, including Regents exams in course grades

Public domain photo

District parents should not expect more information about the surprise reassignment and investigation of Ward Melville High School’s principal, according to Three Village Superintendent of Schools Kevin Scanlon.

Due to federal and state privacy laws, district representatives can’t discuss personnel matters  — and they won’t be able to even after the issue is resolved.

The board had an emergency meeting Wednesday, Nov. 8, after announcing the personnel change, with a public portion that lasted only a couple of minutes, time enough for the board to confirm the interim principal — Paul Gold, previously an assistant principal — and his compensation, as well as to vote to engage the services of Investigative Management Group.

District parent Qin Wu at the Nov. 15 board meeting spoke out in support of former principal William Bernhard and indicated parents were concerned for high school seniors.

“As a parent, I hope the investigation will be fair and transparent, and maybe even as soon as possible to resolve the issue and have everything come back to normal,” Wu said.

Scanlon told TBR News Media after the meeting that even though such transparency is not possible, Wu and other parents have nothing to worry about regarding their children’s education or the district’s reputation.

“I think the school is in good hands, and the acting administration is doing a wonderful job,” he said. “The educational system is still intact. Classes will remain, students will still go to college. No one’s going to be harmed that way,” adding, “If that is the fear that is being propagated, that’s wrong.”

Board president Susan Rosenzweig, a district parent herself, also spoke against percolating speculation and hearsay on social media. “Don’t buy in,” she advised. “Let due process take its place. It’s tough, I know.”

Regents exams as part of final grade

During the meeting, the board tabled any decision regarding the so-called “Do No Harm” rule, the policy of including Regents scores as part of a student’s final grade only if that score improves the grade.

The policy, which proponents say supports students who don’t test well, was instituted during the COVID-19 pandemic and temporarily extended last year after a group of parents petitioned the district.

Assistant Superintendent Brian Biscari shared the consensus recommendation that came after “tremendous discourse” by the district’s grading committee to include the exams at 10% — down from the 12% that has been the policy outside the reprieve of the last few years.

Biscari also took issue with the label “Do No Harm” since it implies acting in any other way will inflict harm on students, when part of the concern was that students may not take exams seriously if they don’t count toward final grades.

“It was a very student-centered conversation,” he said. “Never was the conversation about what the district is going to look like or how we’re going to present data. It was all in relation to students.”

But for freshman board member Karen Roughley, a long-time supporter of the policy, a 2% decrease is not enough. “There are many different ways to gauge a child’s understanding of the concepts than just sitting for one single test that means so much,” she said.

Biscari noted that some form of testing is required by the state, and removing any pressure from the Regents exam could backfire for students who need to take licensure exams or other higher-stakes tests in the future.

“We, as a district, would want to arm kids in how to address that anxiety and deal with it so they can effectively take tests, rather than eliminating that stress,” he said. “It’s almost an avoidance in some cases that we’re not teaching kids these skills that they are going to need in their lives.”

The board opted to wait on voting about the issue until it could hear forthcoming data from the state to see whether exam scores changed when students knew low scores would not be included in their final grade, and to learn more about how comparable Long Island districts are using Regents scores for classroom grades.

Cell phone policy

Scanlon also updated the board on the ongoing cell phone policy committee’s work, laying out the current thinking for parameters around student cell phone use in schools.

Currently the committee is ironing out how to best enforce the proposed new policy, though Scanlon emphasized that any consequences will be decided by building principals or the district, and will not be a one-size-fits-all consequence determined by a planning committee.

The board engaged the committee to look into changes after it became apparent that issues of use during instructional time, inconsistent enforcement across classes and cyberbullying were popping up at the secondary schools.

“It’s fully recognized by the teaching staff and the administration that cell phones are an issue, and then we heard loud and clear from the student representatives on the committee that yes, they agree, cell phones are an issue,” Scanlon said. “Everyone seemed to agree: We’ve got a problem.”

He said the final committee recommendations should be available for the Nov. 29 board meeting.

by -
0 266
Photo by Katja Fuhlert from Pixabay

The U.S. Food and Drug Administration has approved a new COVID-19 booster, which will protect against the virus’s circulating strain.

With hospitalizations and cases rising in Suffolk County and nationwide, single booster shots from Pfizer-BioNTech and Moderna should be available soon.

Local doctors recommended that people at the highest risk consider getting the shot.

That includes those with other medical issues, such as a 45-year-old smoker or a 65-year-old with diabetes.

Health care providers generally believe people who recently had COVID have at least three months of protection, although no definitive rule exists.

“If you had it in August, you probably don’t need to get a booster now,” said Dr. Sharon Nachman, chief of the division of pediatric infectious diseases at Stony Brook Children’s Hospital. “If you had it in January and you’re high risk, you should get it now.”

Nachman added that no study has indicated the age at which patients should get a booster shot.

People should consult their physicians to determine how their underlying health can affect the decision to get an updated vaccine.

“That gets back to the doctor-patient relationship,” Nachman said.

People who are 70 years old and planning a cruise that stops in several ports might want to get a shot at least two weeks before they travel because “the last thing you want happening is to be hospitalized in a foreign country,” Nachman said.

Nachman suggested that this vaccine, like the others that people have taken, won’t prevent illnesses but will keep people from shedding the virus and can reduce the symptoms and duration of an infection.

The FDA approval of the current vaccine is welcome news because it is a “good match” for the current strain, Nachman indicated.

It’s difficult to predict how much protection the current vaccine will provide for whatever strain might be circulating in February.

When a higher percentage of the population receives the vaccine, the likelihood of new variants declines, she added.

by -
0 325
As children return to school this fall, doctors in Suffolk County expect COVID-19 cases to rise. Photo by Ronny Sefria from Pixabay

People may think COVID-19 is out of sight and out of mind, but the virus, which is still around and is making people sick, doesn’t care. 

The new variant of COVID, EG.5, or “Eris,” is making people sick in the area, with hospital admissions and visits creeping up over the last few weeks.

Left, Dr. Gregson Pigott, commissioner of the Suffolk County Department of Health Services. Right, Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital. Left file photo; right file photo from Stony Brook Medicine

As of Aug. 9, 105 patients were hospitalized with COVID across the entire Northwell system, including 82 people on Long Island. That compares with 63 hospitalized patients on July 9, with 46 on Long Island exactly a month earlier.

That’s also the case for other area hospitals, doctors said.

“The numbers are definitely going up,” said Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital. “That’s probably a snapshot of what we expect in the fall and the winter.”

Dr. Gregson Pigott, commissioner of the Suffolk County Department of Health Services, explained that COVID-19 is “no longer an emergency” but is “still with us and we continue to see new variants.”

In an email, Pigott explained that the county has seen a “slight uptick in hospitalizations” that is still low in comparison to the earlier days of the pandemic.

He urged those at high risk to take precautions that could include avoiding crowded places, wearing a mask and meeting people at outdoor venues rather than indoors.

While the numbers of people sick with COVID are substantially lower than they were during the worst of the pandemic in 2020, health care professionals suggested that the fall and winter could be challenging for families, particularly as children return to school.

“The first two weeks of school, every kid is sick,” said Nachman. “Come November-ish, that’s when we see” that increase.

Dr. Bruce Hirsch, attending physician in Infectious Disease at Northwell Health, also anticipates a rise in COVID-19 cases coming this fall and early winter.

“I think there’s a very good chance that a lot of people will be having COVID,” he said.

Hirsch added that the symptoms for those people who don’t have underlying medical conditions, such as cardiac or lung-related problems, are likely to be considerably milder than they had been in the early stages of the disease, when no one had resistance.

“The sickness will not have the severity and mortality except in those of us who are unfortunate to have weak immune systems, other health problems or who are elderly or frail,” Hirsch said.

Pigott added that Eris, which is a subvariant of omicron, is not a variant of interest or concern, according to the World Health Organization.

Vaccine options

Doctors urged people to consider getting vaccines for COVID, the flu and respiratory syncytial virus for this coming fall.

The Centers for Disease Control and Prevention and the U.S. Food and Drug Administration are expected to approve the latest booster for COVID in late September or early October.

The newest booster, which should be available from Pfizer, Novavax and Moderna, should include protection against the latest COVID strain.

“The new booster formulation is much more similar and much more protective [against] the current strains,” Hirsch said. “The booster available now is protective against a couple of strains ago.”

Pigott urged people to get the new vaccines in the fall when they become available and before the holidays.

The vaccination may not prevent infection or all symptoms, but doctors suggested it would make illnesses shorter and less severe and could make the virus less infectious.

That could be particularly helpful for those who might otherwise develop more significant symptoms as their bodies attempt to fight off the virus.

Health care professionals suggested residents could receive several vaccines at the same time, enabling their immune systems to build resistance to a host of potential health threats.

“Our immune systems can chew gum and walk at the same time,” said Hirsch. “They are miraculous at reacting to all kinds of things every day anyway. The immune system is more than up to the challenge of handling two [shots] at the same time.”

Receiving several shots at once could give people a sore arm and a short-term fever that will likely respond to Tylenol, Nachman said.

“The science has shown that if you give a bunch of vaccines, you get a great response to everything,” Nachman added.

People who would prefer to get the vaccines in separate doses should space them out over several weeks, rather than getting one after another on consecutive days, she said.

Warning to pregnant women

Apart from viral infections, doctors warned pregnant women and those who might get pregnant  this winter about the ongoing shortage of a form of penicillin to treat syphilis.

Penicillin G benzathine, or Bicillin, is expected to be in short supply through the start of the summer of 2024.

The medicine is not only the only treatment recommended for pregnant people with syphilis, but is also the only one recommended for infants.

“We are prioritizing that medicine specifically only for that vulnerable population,” said Nachman.

The dangers of syphilis in pregnant women are significant, with the CDC estimating that about 40% of babies born to women with untreated syphilis can be stillborn or die from the infection.

Other dangers from syphilis include bone damage, anemia, enlarged liver and spleen, jaundice, nerve problems causing blindness or deafness, meningitis and skin rashes.

With cases of congenital syphilis more than tripling in recent years, the demand for Bicillin has exceeded the supply.

“It has been a concern for those in our Bureau of Sexually Transmitted Diseases,” Pigott explained. “They have been in consultation with the state. We defer to the state regarding supply.”

Locally, hospitals have been exploring other options without much success.

“We are looking for alternatives” to Bicillin, said Nachman, but “we are not necessarily finding them.”

Doctors urged pregnant women who think they might have syphilis to get tested to protect themselves and their unborn children.

by -
0 1069
Left, Dr. Daniel Jamorabo, gastroenterologist at Stony Brook Medicine and assistant professor of medicine in the Division of Gastroenterology and Hepatology at Stony Brook University’s Renaissance School of Medicine. Right, Dr. David Purow, chairman of Medicine-Gastroenterology at Huntington Hospital. Left by Stony Brook Medicine/Jeanne Neville; right from Northwell Health

No one rushes to make a reservation at a pre-colonoscopy restaurant with a cleansing and well-reviewed special of the day. 

In fact, for most people, the preparation for a potentially lifesaving diagnostic procedure is somewhere between unpleasant and unpalatable.

That, however, may have changed as the U.S. Food and Drug Administration recently approved another incremental improvement in the colonoscopy preparation that could make the preparation and the procedure — which can detect early signs of cancer — less bothersome.

Manufactured by Sebela Pharmaceuticals, Suflave is a low-volume preparation that tastes like a lemon-lime sports drink. It should be available in August.

“Patients really like” Suflave, with about 80 percent finding it palatable, said Dr. Daniel Jamorabo, a gastroenterologist at Stony Brook Medicine and assistant professor of medicine in the Division of Gastroenterology and Hepatology at Stony Brook University’s Renaissance School of Medicine. 

Jamorabo called it a “wonderful addition to the bowel preparations that are out there.”

Jamorabo said the ingredients in most preparations are the same: the difference in the Suflave preparation seems connected to the flavor.

The thinking in the gastrointestinal community is that “we need to find a preparation” that is more pleasant, said Dr. David Purow, chairman of Medicine-Gastroenterology at Huntington Hospital. “That will capture more people who are somewhat reluctant to have a colonoscopy.”

Colonoscopies are a “necessary screening procedure,” Purow added, and health care professionals in the field don’t want the discomfort during preparation to discourage people from getting the procedure.

Indeed, doctors have a much higher success rate with patients when they detect evidence of colon cancer early.

Getting it right

Doctors suggested that the success of preparing for a colonoscopy varies.

Jamorabo estimated that around 10% of patients may not take all the steps necessary to have the screening.

In those circumstances, these patients have to reschedule the procedure and go through drinking fluids that clear out their systems more effectively.

Gastroenterologists urged people to ask questions if they don’t understand any of the steps they need to take to prepare.

For some patients, the COVID-19 pandemic delayed their routine colonoscopy visits, as people stayed away from hospitals and medical care facilities during periods of highest viral infection.

Jamorabo added that colon cancers have started to show up in younger people.

In 2018, the American Cancer Society recommended lowering the age for screenings from 50 to 45.

“It’s showing up more” in people under 50, said Jamorabo. “It may even go lower.”

Doctors discovered stage three colon cancer in late actor Chadwick Boseman before he was 40.

“We don’t know yet” why it’s causing cancer in younger people, Jamorabo added, but “it’s not rare. It’s been going on for a couple of years. We can’t write it off as some statistical anomaly.”

Early symptoms

People can and should be on the lookout for symptoms that might indicate colon cancer.

Unintentional weight loss, such as losing 10 pounds or more in three to four months without changing diet or exercise regimen, could indicate a problem.

Blood in the stool, changes in bowel habits and ongoing constipation could also require medical attention.

More subtle signs, such as fatigue, shortness of breath or decreased appetite, could indicate that people are losing blood in their stool.

As for the overlap between COVID and colon cancer, Jamorabo believes that the ongoing inflammation from the SARS-CoV2 virus could predispose people to cancer.

“I don’t think enough time has elapsed” to know if there’s a link between the virus and colon cancer, he added.

With anxiety building over big-picture issues like global warming and an intensely divided population, people are likely increasingly worried about the state of the world.

“Most gastroenterologists are probably busier than they’ve ever been,” Purow said. “Some of that is probably due to the times in which we are living.”

Stress and anxiety can cause gastrointestinal symptoms that manifest in different ways.

Even with less concern about the pandemic, doctors are still seeing more people with alcoholic liver disease, as some turned to alcohol to relieve their ongoing anxiety.

“We’re trying to expand our network of dietitians and mental health professionals that we’re working with,” said Purow.

Information is power

An important tool in preventing colon cancer involves tracking the colon’s health through colonoscopies.

Having Suflave on the market could “lower the dread” of having a colonoscopy, Jamorabo noted. “We need to make the logistics of the preparation easier.”

by -
0 196
Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children's Hospital. File photo from Stony Brook Medicine

With COVID-19 pandemic restrictions in the rearview mirror, residents have been returning to the open road and the open skies, visiting places and people.

In addition to packing sunscreen, bathing suits and cameras, local doctors urge people to check the vaccination status for themselves and their children, which may have lapsed.

“During COVID, many people did not keep up with their vaccines,” said Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital. “That has led to a decrease in the amount of children who are vaccinated.”

Last week, the Centers for Disease Control and Prevention issued a health advisory to remind doctors and public health officials for international travelers to be on the lookout for cases of measles, with cases rising in the country and world.

As of June 8, the CDC has learned of 16 confirmed cases of measles across 11 jurisdictions, with 14 cases arising from international travel.

Measles, which is highly contagious and can range from relatively mild symptoms to deadly infections, can arise in developed and developing nations.

Measles can be aerosolized about 60 feet away, which means that “you could be at a train station and someone two tracks over who is coughing and sneezing” can infect people if they are not protected.

The combination of increasing travel, decreasing vaccinations and climbing levels of measles in the background creates the “perfect mixture” for a potential spread of the disease, Nachman said.

Typical first symptoms include cough, runny nose and conjunctivitis.

Conjunctivitis, which includes red, watery eyes, can be a symptom of numerous other infections.

“Many other illnesses give you red eyes,” Nachman said, adding, “Only when you start seeing a rash” do doctors typically confirm that it’s measles.

People are contagious for measles when they start to show these symptoms. Doctors, meanwhile, typically treat measles with Vitamin A, which can help ease the symptoms but is not an effective antiviral treatment.

As with illnesses like COVID, people with underlying medical conditions are at higher risk of developing more severe symptoms. Those with diabetes, hypertension, have organ transplants or have received anticancer drugs or therapies can have more problematic symptoms from measles.

In about one in 1,000 cases, measles can cause subacute sclerosing panencephalitis, or SSPE. About six to 10 years after contracting the virus, people can develop SSPE, which can lead to coma and death. 

In addition to children who need two doses of the measles vaccine, which typically is part of the measles, mumps and rubella vaccine, or MMR, doctors urge people born between 1957 and 1985 to check on their vaccination status. People born during those years typically received one dose of the vaccine. Two doses provide greater protection.

Two doses of the MMR vaccine provide 97% protection from measles. One dose offers 93% immunity, explained Dr. David Galinkin, infectious disease specialist at Port Jefferson-based St. Charles Hospital.

People born before 1957 likely had some exposure to measles, which can provide lifelong immunological protection.

Nachman also urged people to speak with their doctor about their vaccination status for measles and other potential illnesses before traveling. People are protected against measles about two weeks after they receive their vaccine.

Doctors suggested that the MMR vaccine typically causes only mild reactions, if any.

Tetanus, Lyme

In addition to MMR vaccines, doctors urged residents to check on their tetanus vaccination, which protects for 10 years.

“The last thing you want to do is look for a tetanus vaccination in an international emergency room,” Nachman added.

During the summer months, doctors also urged people to check themselves and their children, especially if they are playing outside in the grass or near bushes, for ticks.

Intermediate hosts for Lyme disease, a tick typically takes between 36 to 48 hours from the time it attaches to a human host to transmit Lyme disease.

Nachman suggested parents use a phone flashlight to search for these unwelcome parasites.



123...32Next Page 1 of 32
TBR News Media is your local news and entertainment website.
We provide you with the latest breaking news and information for your community.
Contact us: [email protected]

Most Viewed

©