Arts & Entertainment

Northport Scout Joseph Luft on the trail and steps he rebuilt on the Vanderbilt Estate. Photo from Vanderbilt Museum
Project enhanced beauty of estate and safety for visitor-hikers

Joseph Luft rebuilt the steps on a steep trail at the Suffolk County Vanderbilt Museum as part of his project to become an Eagle Scout.

Luft, a junior at Northport High School and member of Troop 41, reconstructed the hill and the steps leading from the Wishing Well Garden at the Vanderbilt Mansion down to the Boathouse on the waterfront. Jim Munson, the Vanderbilt’s operations supervisor, said the old steps had begun to fail and became a safety concern. On a Troop 41 trip to the Museum in 2020, Luft noticed the deterioration and decided he wanted to make the trail his Eagle project, Munson said.

Above right: Kyle Roelofs, Michael Monda, Connor Jorgensen, James Posillico, Joe Luft, Ryan Edebohls, Will Ponder, David Luft. Photo by Virginia Luft.

Elizabeth Wayland-Morgan, executive director of the Museum, said, “We’re grateful to Joe for his important contribution to the Vanderbilt. The rebuilt hill, steps, and trail are crucial not only to the beauty and accessibility of the estate grounds, but also to the enjoyment and safety of visitors who hike the trail.”

Luft, who chose the project because he loves hiking, started planning it a year ago. He began working on the trail in August and with help from his family, troop, and friends completed work on October 2. He thanked “14 incredible scouts” for helping him raise $1,324 by holding a car wash and for working with him to complete the trail.

“The most surprising aspect of the project,” Luft said, “was how willing people were to lend a hand whenever I needed help or volunteers. Whether it was purchasing supplies or scrubbing down cars, someone was always there with me to help make sure it was done right. The people at the Vanderbilt were incredibly flexible with timing and with occasionally lending us one of their golf carts to haul tools.”

Luft, who is about to complete the Eagle Scout requirements, said it felt “amazing” to finish the project. “It was a huge weight lifted off my shoulders, a lot of stress and work. But the project was finally done and all I could do was sit back and look at everything accomplished with a smile.”

He said he learned a lot about how to organize fundraisers and how to write emails in a professional manner. “I also learned something about time management and how strong a community Northport is when it comes to people supporting each other.”

By Melissa Arnold

Putting on a stage production is about so much more than actors and musicians. The staff working behind the scenes — stage managers, set builders, makeup artists and costume designers — are just as important, and their skills can make the difference between an excellent show and a mediocre one.

Costume designer Jason Allyn is all about going the extra mile to create the perfect outfit, down to the jewelry, fine detail work and sequins. He sat down recently to talk about the costume design process and his new stage home at Theatre Three in Port Jefferson.

When did you first become interested in costume design?

My mother took me to musicals when I was young, and she was also a seamstress. As for me, I’m a huge comic book nerd, a big Marvel and DC Comics nut. As a kid, I loved the stories and the heroes, but I also loved their costumes! Since I knew how to sew from my mom, I would make and recreate those outfits because I wanted to be them. But I never had the thought of wanting to be a costume designer, at least not at that time.

So when did you start thinking about making it your career?

I did both theater and sports when I was growing up, and even worked at Theatre Three in high school. I went to college for musical theater, and we had to spend a certain number of credit hours on different parts of the process — acting, lighting, design. I found myself doing a lot of costume hours because of my natural love for fashion, period movies and sewing. I got a job working at a local theater as a director, and ended up designing some things. It snowballed from there, becoming a real love.

Why is costume design so important to a production?

It’s a piece of art, just like any other aspect of the show. People know when you’re giving them a bad product, and they know when you’re giving it your best effort.

How did you start working at Theatre Three?

My last job ended around the same time as the pandemic began. It was such a dark time for so many of us in theater, and I wasn’t sure I was ever going to be able to find work again. I began considering going in a different direction with my career. But then my best friend asked me to work with her on costuming a production of The Nutcracker, and after such a long time focusing on directing, it really rekindled my love for costuming. 

I had borrowed a couple of pieces from Theatre Three, and when I went to the theater to return them I had a wonderful, two-hour conversation with [Theatre Three Executive Artistic Director] Jeffrey Sanzel. He ended up calling me some time later once the theater reopened and invited me to interview for their wardrobe supervisor position and I started work in August.

Tell us a bit about your process. How do you go about designing a costume?

First, I sit down and read the entire script, taking notes as I go. If it’s a musical, I listen to the original cast recording and sometimes try to find clips online to use as references. Some roles are very particular and iconic, like Maria’s white dress in West Side Story, which you really need to stick to. Other shows allow for the opportunity to design in the ways I feel would be most interesting. For example, I’m working on the costumes for Steel Magnolias right now for the spring, and the main character wears pink, but there is a lot of freedom there. 

Jeff and I will sit down and talk about each character and my ideas. Sometimes I’ll sketch or bring in pictures of other looks I enjoy, and he’ll make suggestions or changes. It’s a collaborative process. 

Where do you get the materials for the costumes?

Sometimes they are a part of my existing collection, other times we get them at thrift stores or I sew them. I dye pieces to get the right colors we need, and I love using wigs. I get my fabric from JoAnn’s, and the actors and staff are always excited to hear what I’m making next. With Barnaby Saves Christmas, I decided to use different styles for the boy and girl elves, with different colors and details to denote rank. It’s like creating an entire world.

Do you have a favorite fabric?

Cotton is great for children’s theater because it’s washable and doesn’t bleed — children’s shows are very active and so it’s important for the costumes to be durable and easy to care for. As for mainstage shows, it’s more about what would be appropriate for the period and setting of the show. I love confetti dot, as well as anything with sequins or a little glam. Sparkle really makes a costume pop and gives a great effect. There’s something about it as an audience member that’s exciting.

Do you have favorite shows you’ve done costuming for?

Nine the Musical, Dirty Rotten Scoundrels, The Wizard of Oz, Beauty and the Beast and  Cinderella are all on my list.

What do you love most about costuming?

Honestly, I love designing for women. Men are wonderful, but they’re simple — you put on a pair of pants and they’re good to go. But women come in so many different shapes, sizes and styles of dress. It’s all beautiful. There’s nothing that makes me happier than when a woman tries on her costume and says to me, “I feel so pretty!” or when a man says, “Wow, I feel great in this.” Everyone is gorgeous and deserves to feel that way. Each person is important and matters to me. 

Beyond that, it’s a joy for me to be in the audience and watch the faces of audience members, especially children, when a character comes onto the stage.

What are you enjoying about working at Theatre Three?

It’s such a loving work environment. Everyone is so supportive of everyone else, and it’s a joy to be a part of that. After the pandemic, I truly didn’t think I was going to be able to work again. Jeff is a wonderful director to exchange ideas with — he truly listens and gives me the freedom to be creative, and it means the world to me that he likes my work. 

I also love that I have my own workshop space there where I get to spread my wings and be creative. They even painted it purple for me and embrace how obsessive I am about organization. It’s my dream job!

METRO photo

By Michael Ardolino

Michael Ardolino

The new year is around the corner. Many homeowners yearning for a fresh look may think about renovating their homes or making small changes to their house. Here’s a piece of advice — always keep in mind that you will sell your home one day. With the market staying steady for sellers, it may be sooner than later.

Stay relevant

Even if you’re not thinking of selling your home currently, when painting, buying new fixtures, working on the outside, or making any change, stay up to date with the latest trends.

There are plenty of ways to find looks that are pleasing to you while you’re living in the house and still trendy. One day when you are ready to sell your home, you’ll be glad you did. It will mean less time and money to get it ready for market.

The first step is to check out popular social media apps such as Pinterest and some home decor websites or magazines. Some beautiful colors are trending for 2022. 

For those who like a bright pop of color, purple will be a hot one. It works best in pillows or select pieces and the color pairs well with neutrals or a jewel tone such as red. Green is becoming another popular choice. The color is an earthy tone that is ideal for walls, and just like taupe, warm browns and off-whites, it works well with various decors.

Be bold with furniture and home decor items and mix materials such as metal, stone, wood and different fabrics to add an inviting look to a room. 

Homes with kitchens that open into a living or family room are very popular. At the same time, today’s buyers like to see some definition between areas so consider a kitchen island or area rug in the dining room.

As you walk around your house, remember with more work-from-home options and many people still exercising at home, setting up a room or area that can be identified as office space, a study room or yoga studio is still big. Remember your ceilings when updating your home, too. Textured ceilings are dated so work on replacing popcorn, textured or stucco to freshen up your home.

Breath of fresh air

One of the biggest trends over the last couple of years has been the growing appreciation for the outdoors and fresh air. No matter what time of year it is, you can think about creating a yard that is an oasis for you and future occupants with luscious gardens, or fun additions such as fire pits and porch swings.

Takeaway

Many sellers who real estate professionals have staged or painted for often comment, “Why didn’t I do this sooner so I could have enjoyed it! Now I don’t want to move!”

You don’t have to be selling your house in the next few months to keep your home market-ready while still enjoying it yourself. You also never know when the opportunity to sell will arrive. Over the last couple of years, many people who weren’t even thinking of selling decided to do so to take advantage of the seller’s market or because a person or real estate professional reached out to them and asked them to consider selling.

Next year is going to be an exciting one in real estate, and I look forward to sharing with you more tips plus market news in this column during 2022. So, let’s talk.

Michael Ardolino is the Founder/Owner-Broker of Realty Connect USA.

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NSAIDs and acetaminophens are not risk-free

By David Dunaief, M.D.

Dr. David Dunaief

What’s in your medicine cabinet? If you’re like most people, you have your typical “go-tos” for pain relief, fever or inflammation. You might have aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) and acetaminophen (Tylenol). 

Familiar NSAIDs include ibuprofen (Advil, Motrin) and naproxen sodium (Aleve). Over 70 million prescriptions for NSAIDs are written each year in the U.S., and Americans consume more than 30 billion doses, once over-the-counter (OTC) use is factored in (1).

According to a poll of these regular users of OTC NSAIDs, a substantial number — 60 percent — were unaware of their dangerous side effects (2). Acetaminophen is used frequently, as well. On a weekly basis, one quarter of Americans take it. Unfortunately, many think of these drugs as relatively benign. In fact, I find that until I specifically ask about their use, most patients don’t include them in a list of their medications.

NSAID risks

Unfortunately, NSAIDs, according to the Centers for Disease Control and Prevention, are responsible for 7,600 deaths annually and 10 times that number in hospitalizations (3). These are not medications that should be taken lightly. 

NSAIDs increase the risk of several maladies, including heart attacks, gastrointestinal bleeds, exacerbation of diverticular disease, chronic arrhythmias (abnormal heartbeats) and erectile dysfunction. In some instances, the cardiovascular effects can be fatal.

These risks prompted the FDA to strengthen the warning labels on non-aspirin NSAID labels, advising that those taking NSAIDs should immediately seek medical attention if they experience chest pain, shortness of breath or trouble breathing, weakness in one part or side of their body, or slurred speech (4).

Adverse side effects of NSAIDs

In a case control study using the UK Primary Care Database, chronic users of NSAIDs between ages 40 and 89 had a significantly increased risk of a serious arrhythmia (abnormal heartbeat) called atrial fibrillation (5).

Interestingly, chronic users were defined as patients who took NSAIDs for more than 30 days. Those patients who used NSAIDs more than 30 days had a 57 percent increased risk of atrial fibrillation. A Danish study reinforces these results after the first month of use (6). This is not very long to have such a substantial risk. For patients who used NSAIDs longer than one year, the risk increased to 80 percent. 

Caution should be used when prescribing NSAIDs or when taking them OTC. Atrial fibrillation is not an easy disease to treat.

NSAIDs also increase the risk of mortality in chronic users. Older patients who have heart disease or hypertension (high blood pressure) and are chronic NSAIDs users are at increased risk of death, according to an observational study (7). Compared to those who never or infrequently used them over about 2.5 years, chronic users had a greater than twofold increase in death due to cardiovascular causes. High blood pressure was not a factor, since the chronic users actually had lower blood pressure. Yet I have seen with my patients that NSAID use can increase blood pressure. 

Is acetaminophen better?

Acetaminophen does not cause gastrointestinal bleeds, arrhythmias and deaths due to cardiovascular events that NSAIDs can. However, the Food & Drug Administration announced in 2011 that acetaminophen should not exceed 325 mg every four to six hours when used as a prescription combination pain reliever (4). The goal is to reduce and avoid severe injury to the liver, which can cause liver failure. 

There is an intriguing paradox with acetaminophen: Hospitals typically dispense regular-strength 325-mg doses of the drug, whereas OTC doses frequently are found in extra-strength 500-mg tablets, and often the suggested dose is two tablets, or 1 gram. At the FDA’s request, Tylenol lowered its recommended daily dosage for extra strength Tylenol to no more than 3 grams a day to lower the risk of liver damage.

I have patients who have exceeded this, thinking that, because it is OTC, this is “safe.” Unfortunately, this is not true and can be dangerous.

The FDA’s recommendations for limiting the dose result from a conglomeration of data. For instance, one study that showed acute liver failure was due primarily to unintentional overdoses of acetaminophen (8). Accidental overdosing is more likely to occur when taking acetaminophen at the same time as a combination sinus, cough or cold remedy that also contains acetaminophen. OTC and prescription cold medications can contain acetaminophen.

Of course, if you already suffer from liver damage or disease, you should consult with your physician before taking any medications.

In order to be aware of potentially adverse events, you have to be your own best advocate and read labels. Remember to tell your physician if you are taking OTC medications.

If you are a chronic user of NSAIDs or acetaminophen because of underlying inflammation, you may find an anti-inflammatory diet, which is usually plant-based, is an effective alternative.

References:

(1) Medscape.com, 2021 Oct 21 (emedicine.medscape.com/article/816117-overview). (2) J Rheumatol. 2005;32;2218-2224. (3) Annals of Internal Medicine, 1997;127:429-438. (4) fda.gov (5) Arch Intern Med. 2010;170(16):1450-1455. (6) BMJ 2011;343:d3450. (7) Am J Med. 2011 Jul;124(7):614-620. (8) Am J Gastroenterol. 2007;102:2459-2463. 

Dr. David Dunaief is a speaker, author and local lifestyle medicine physician focusing on the integration of medicine, nutrition, fitness and stress management. For further information, visit www.medicalcompassmd.com. 

A scene from 'Elf'

Comsewogue Public Library, 170 Terryville Road, Port Jefferson Station will screen a series of holiday movies from Dec. 27 to Dec. 30 at 2 p.m. Join them for Elf on Dec. 27, National Lampoon’s Christmas Vacation on Dec. 28, It’s a Wonderful Life on Dec. 29 and Miracle on 34th Street on Dec. 30. Open to all. Advance registration is required as seating is limited. To register, visit www.cplib.org or call 928-1212.

Pat Darling ran Santa's Workshop in Port Jefferson Village. File photo

By Allan Varela

The very successful 25th celebration of Port Jefferson’s Charles Dickens Festival has come to a close for this year, with energetic plans already in the works for the 26th celebration in 2022. Sadly, one of the many bright spots of the event, Santa’s Workshop, will not be returning. The historic Phillips Roe House, aka the Drowned Meadow House located on the corner of Barnum Avenue and West Broadway, which has played host to the workshop all these years, is officially becoming a year-round museum.

For the last seven Charles Dickens Festivals, Santa Claus and his elves came to life through the tireless work of the acclaimed confection artist Pat Darling. The whimsical workshop has welcomed both the young and young at heart to step back in time and reflect on the storybook charm of cherished memories of an era that has quietly faded. 

Snowflakes glistening high above the elaborate confection nutcrackers and giant turrets that have adorned the beautiful displays throughout the workshop area set the mood, while children were greeted by sugar trees and toy soldiers.

The wonderment continued into Hollyberry’s bedroom, an elaborate vignette that featured Hollyberry anticipating the night before Christmas as she busily wrapped presents. The nightscape background featured Santa in his sleigh high in the night sky, coming to visit the workshop. 

And visit he did, as the third room presented the real live Santa in all his glory, sitting in a giant arched chair as he greeted families. Smiles and happiness are the legacy of this special exhibit.

Pat Darling has charmed literally thousands of people over the years with her creative vision, inspiring execution and attention to detail that made Santa’s Workshop such a very special happening for the Dickens Festival. The workshop will be sorely missed, but the community at large will be eternally grateful for Ms. Darling’s resolute efforts.

Allan Varela serves as chair for the Greater Port Jefferson-Northern Brookhaven Arts Council which hosts the Port Jefferson Charles Dickens Festival.

Photo by Gerard Romano

SILVER BELLS

Gerard Romano of Port Jefferson Station was out with his camera on Dec. 17 ‘looking for something appropriate for the season’ when he spied these pretty bells adorning the door of the Belle Terre Village Hall and took the perfect shot. Happy Holidays!

Send your Photo of the Week to [email protected]

Chocolate Dipped Candied Orange Peels

                                                Recipe courtesy of Brandi Milloy on behalf of Sunkist

Chocolate Dipped Candied Orange Peels

Prep time: 5 minutes
Cook time: 1 hour
Servings: 4

Ingredients:

4 Sunkist Navel oranges
3 cups water
1 1/2 cups sugar
1 teaspoon vanilla extract or vanilla bean paste
1 cup dark chocolate, melted

Directions:

Rinse and dry oranges. Slice both ends off each orange. Using paring knife, carefully score each orange in quarters then remove peel from each section, trying not to get too much pith. Slice peels into 1/4-inch strips. Add to pot and cover with water and sugar; stir. Bring to boil. Turn heat to medium-low until water reaches soft simmer. Simmer 45 minutes. Add vanilla before turning off heat and stirring. Remove peels from syrup and cool on wire rack. Roll in sugar to coat. Dry at least 4 hours, or overnight. Dip candied orange peels one at a time in dark chocolate. Place on parchment paper to set up and harden. Store in airtight container.

See video here.

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It’s the season for giving.

New York Blood Center will hold its 9th annual blood drive at The Paramount, 370 New York Ave., Huntington on Sunday, Dec. 26 from 9 a.m. to 3 p.m.

Your donation will help to save up to THREE lives. Our community hospitals need your help! Please share this lifesaving gift.

All donors at The Paramount Blood Drive will also receive one (1) pair of tickets to any one of these upcoming shows…while they last!

*The Disco Nights – Friday, January 7th (DISCO), *Best of The Eagles – Thursday, January 14th (CLASSIC ROCK), *Jimmy Kenny & The Pirate Beach Band – Saturday, January 15th (TROP ROCK), *Scotty McCreery – Thursday, January 27th (COUNTRY), *Icons of Vinyl – Friday, January 28th (CLASSIC ROCK), *Voyage – Friday, February 4th (JOURNEY TRIBUTE), *Randy Houser – Thursday, February 10th (COUNTRY)

Eligibility Criteria:
• Bring ID with signature or photo.
• Minimum weight 110 lbs.
• Eat well (low fat) & drink fluids
• No tattoos for past 12 months
• Age 16 – 75 (16-year olds must have parental permission. Age 76 and over need doctor’s note)

For questions concerning medical eligibility call 1-800-688-0900 www.nybc.org.
For more information, please call The Paramount @ 631-673-7300.

Ramana Davuluri

By Daniel Dunaief

Ramana Davuluri feels like he’s returning home.

Davuluri first arrived in the United States from his native India in 1999, when he worked at Cold Spring Harbor Laboratory. After numerous other jobs throughout the United States, including as Assistant Professor at Ohio State University and Associate Professor and Director of Computational Biology at The Wistar Institute in Philadelphia, Davuluri has come back to Long Island. 

As of the fall of 2020, he became a Professor in the Department of Biomedical Informatics and Director of Bioinformatics Shared Resource at Stony Brook Cancer Center.

“After coming from India, this is where we landed and where we established our life. This feels like our home town,” said Davuluri, who purchased a home in East Setauket with his wife Lakshmi and their six-year-old daughter Roopavi.

Although Davuluri’s formal training in biology ended in high school, he has applied his foundations in statistics, computer programming and, more recently, the application of machine learning and deep algorithms to the problems of cancer data science, particularly for analyses of genomic and other molecular data.

Davuluri likens the process of the work he does to interpreting language based on the context and order in which the words appear.

The word “fly,” for example, could be a noun, as in an insect at a picnic, or a verb, as in to hop on an airplane and visit family for the first time in several years.

Interpreting the meaning of genetic sentences requires an understanding not only of the order of a genetic code, but also of the context in which that code builds the equivalent of molecular biological sentences.

A critical point for genetic sequences starts with a promoter, which is where genes become active. As it turns out, these areas have considerable variability, which affects the genetic information they produce.

“Most of the genetic variability we have so far observed in population-level genomic data is present near the promoter regions, with the highest density overlapping with the transcription start site,” he explained in an email.

Most of the work he does involves understanding the non-coding portion of genomes. The long-term goal is to understand the complex puzzle of gene-gene interactions at isoform levels, which means how the interactions change if one splice variant is replaced by another of the same gene.

“We are trying to prioritize variants by computational predictions so the experimentalists can focus on a few candidates rather than millions,” Davuluri added.

Most of Davuluri’s work depends on the novel application of machine learning. Recently, he has used deep learning methods on large volumes of data. A recent example includes building a classifier based on a set of transcripts’ expression to predict a subtype of brain cancer or ovarian cancer.

In his work on glioblastoma and high grade ovarian cancer subtyping, he has applied machine learning algorithms on isoform level gene expression data.

Davuluri hopes to turn his ability to interpret specific genetic coding regions into a better understanding not only of cancer, but also of the specific drugs researchers use to treat it.

He recently developed an informatics pipeline for evaluating the differences in interaction profiles between a drug and its target protein isoforms.

In research he recently published in Scientific Reports, he found that over three quarters of drugs either missed a potential target isoform or target other isoforms with varied expression in multiple normal tissues.

Research into drug discovery is often done “as if one gene is making one protein,” Davuluri said. He believes the biggest reason for the failure of early stage drug discovery resides in picking a candidate that is not specific enough.

Ramana Davuluri with his daughter Roopavi. Photo by Laskshmi Davuluri

Davuluri is trying to make an impact by searching more specifically for the type of protein or drug target, which could, prior to use in a clinical trial, enhance the specificity and effectiveness of any treatment.

Hiring Davuluri expands the bioinformatics department, in which Joel Saltz is chairman, as well as the overall cancer effort. 

Davuluri had worked with Saltz years ago when both scientists conducted research at Ohio State University.

“I was impressed with him,” Saltz said. “I was delighted to hear that he was available and potentially interested. People who are senior and highly accomplished bioinfomaticians are rare and difficult to recruit.”

Saltz cited the “tremendous progress” Davuluri has made in the field of transcription factors and cancer.

Bioinformatic analysis generally doesn’t take into account the way genes can be interpreted in different ways in different kinds of cancer. Davuluri’s work, however, does, Saltz said.

Developing ways to understand how tumors interact with non-tumor areas, how metastases develop, and how immune cells interact with a tumor can provide key advances in the field of cancer research, Saltz said. “If you can look at how this plays out over space and time, you can get more insights as to how a cancer develops and the different part of cancer that interact,” he said.

When he was younger, Davuluri dreamt of being a doctor. In 10th grade, he went on a field trip to a nearby teaching hospital, which changed his mind after watching a doctor perform surgery on a patient.

Later in college, he realized he was better in mathematics than many other subjects.

Davuluri and Lakshmi are thrilled to be raising their daughter, whose name is a combination of the words for “beautiful” and “brave” in their native Telugu.

As for Davuluri’s work, within the next year he would like to understand variants. 

“Genetic variants can explain not only how we are different from one another, but also our susceptibility to complex diseases,” he explained. With increasing population level genomic data, he hopes to uncover variants in different ethnic groups that might provide better biomarkers.